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The map label for this gene is ligD

Identifier: 77458324

GI number: 77458324

Start: 2382341

End: 2384887

Strand: Direct

Name: ligD

Synonym: Pfl01_2097

Alternate gene names: NA

Gene position: 2382341-2384887 (Clockwise)

Preceding gene: 77458323

Following gene: 77458327

Centisome position: 37.0

GC content: 61.76

Gene sequence:

>2547_bases
ATGAGCAGGAATCTCGACGACTACAACCGGATGCGCGACTTTTCAGCGACCTCTGAACCGGCGGCTGGCCACCGCCGGGG
CAAGAAACCCGCCGGCGACCACGCCCTGCAGTTCTGCATACAAAAGCACGATGCCTCGCATCTGCATTACGACTTTCGCC
TCGAGCTCGACGGCGCGCTCAAGAGCTGGGCGGTGCCCAAGGGGCCGTCGCTGGATCCCAAGGTCAAGCGGCTGGCGGTG
CACGTTGAGGATCATCCGCTGGACTACGCGACGTTCGAGGGCAGCATTCCCGAGGGGCATTACGGCGCCGGCGATGTGAT
CGTCTGGGATCGTGGCGTGTGGATTCCGTTGGAAGACCCGGAGAAAGCCTACGCCAAGGGCAAGCTCAAATTCGAACTGC
AAGGCGAGAAGCTCGCCGGGGTGTGGAACCTGGTGCGCACCCACATGCCGGGCAAGAAAGAGCAGTGGTTTCTGATCAAG
CATCAGGACGGCGCCGCACGCCCGCAAAGCGATTACGACGTGCTGGTCGCCGAGCCCGACAGTGTGCTCAGCGAGCGCAC
GATCGTCGACAAACCCCGGCTTAGTGCGAAGCAGGTCAAACCCCTTCAAGGCCCGGCGAAAGCACCCCGCAAGTCGGCCT
CGGGCAAGCTCACCGGGGCGCACAAGGCCAAAATTCCCGCGCAGCTCAAACCTCAACTCGCCACCTTGGTGGAGAGCGCG
CCGGAGGGCGATTGGCAATACGAAATCAAGTTCGACGGTTATCGGATCATGGCGCGCATTGATCAGGACGAGGTGCAGTT
GTTCACCCGCAATGGCCATGACTGGACGCACAAGTTGCCAAAGCAGGCGCAAGCCCTGGCGGCGCTGGGCCTGGAGTCGG
CGTGGCTGGATGGTGAGATGGTCGTCGCCGATGCGGACGGCGTGCCTGATTTTCAGGCCCTGCAAAACGCGTTCGATTCG
GGACGCAGCGAAAACATCGTCTATTACCTGTTTGATCTGCCGTATCTGAACGGTGTCGACCTGCGCGAGGTGGCGGTGGA
GGAACGGCGCGCAGCGCTGGCCACCGTTCTGAAAACCCATCAAGACCCGCTGCTGCGTTTCTCCGAAGCGTTCGACGAAA
CCCCGCAGGCGTTGCTCAACAGCGCCTGTCAGATGCGCATGGAAGGCCTGATCGGCAAACGCCTCGGCTCGCCTTACGTG
TCGCGCCGCAGCAGCGACTGGATCAAGCTCAAGTGCAAGCATCGCCAGGAATTCGTGATCGTCGGCTACACCGATCCGAA
AGGCGCGCGCAGTTCGTTCGGCGCACTGTTGCTGGGTCTGCATGATCGTGACAGCGGCGAGTTGCGGTACGCCGGCAAGG
TCGGCACGGGATTCAATGAAACCACCCTCAAGAGCATCCTCGCGCAGCTCAAACCGTTGCGAGTGAAAAAACCGGCAGTG
GCCAACCCGCCCACAGGGTTCGAGGCCAAGGGTGTGCACTGGCTCAAACCGAGTCTGCTGGCGGAAGTGGCGTTCGCCGA
AATGACCCAGGATGGCTCGGTGCGCCATGCCGTGTTCCATGGCTTGCGCGAGGACAAACCGGCCAAGGACATCACCGAGG
AGCGCGCCAAACCCATGAACACTTCAAAGACTGAATCTACCGCCCCGTCCCAATCCGGGCTGGCCGACGGCAAGGTGCGG
ATCACTCATCCCGACCGGGTGATCGATGCCAGCAGTGGCACCACCAAAATGCAGCTGGCCGAGTATTACGCCAGCGTCGC
CGAATGGATTCTGCCGCAGCTCAAGGATCGCCCGGTGGCGCTGGTGCGCGCGCCGGACGGCATTGCCGGTGATCTGTTTT
TCCAGAAGAACGCCGAACACCTGGCGATCCCCGGCATCCGCACACTCGACAAGGAGCTGACCGGCCAGCCGGTGATGCTG
ATCAACAATGCCGAAGCCTTGATCGGCGCGGTGCAGATGAGCACGGTCGAACTGCACACCTGGAACGCCACCACGACGGA
TCTGGACAAGCCCGACCGCTTTGTCCTCGACCTCGACCCGGACCCGGCGCTGCCCTGGAAAAGCATGATCGAAGCCACGG
CACTCACCCTGACCGTGCTGGATGAACTGGGCCTCAAGGCGTTTCTCAAGACCAGCGGTGGCAAGGGCATTCATCTGGTG
GTGCCGCTGACCCGCAAGCATGGCTGGGACGAGGTCAAGGATTTCAGCCACGCCATCGTCACGCACATGGCGAAATTGTT
GCCGGAGCGTTTTTCTGCGGTGTCCGGGCCGAAAAACCGTGTGGGGCGGATCTTCATCGATTACCTGCGCAACGGGCTGG
GCGCCACCACCATTTGCGCCTACGCAGCGCGTACCCGCGAAGGATTACCGGTGTCGGTGCCGCTGTTTCGGGAAGAAGTC
GGCGAGATCAAAGGCGCCGATCAATGGAACGTACACAACGTTCACGAACGGCTCGCGGAAGTAGGCGATGAACCTTGGGC
GGACATCAAGAAAACCCGGCAAAGCATCACGGCCGAGATGCGCAAGCGGGTGGGCATGAAGAAATGA

Upstream 100 bases:

>100_bases
TTGGTGAAGAGTTGCTGAATCCAGGCTATCAGCGCGTCGACCGGATTGCCGTGGTCGCACTGACGGTGACTCGAACAGGC
TGAAACAAGGCAGGTGCAGG

Downstream 100 bases:

>100_bases
TCAGGTGCCGCGCAGCAAGTCGTGGGCGTTGAGCAGGTCGAAGGCGACTTGCGGATTGTTTTCCAGGCCACGGCGGATGG
CGGCGGGGATGGTTTTGCGA

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 848; Mature: 847

Protein sequence:

>848_residues
MSRNLDDYNRMRDFSATSEPAAGHRRGKKPAGDHALQFCIQKHDASHLHYDFRLELDGALKSWAVPKGPSLDPKVKRLAV
HVEDHPLDYATFEGSIPEGHYGAGDVIVWDRGVWIPLEDPEKAYAKGKLKFELQGEKLAGVWNLVRTHMPGKKEQWFLIK
HQDGAARPQSDYDVLVAEPDSVLSERTIVDKPRLSAKQVKPLQGPAKAPRKSASGKLTGAHKAKIPAQLKPQLATLVESA
PEGDWQYEIKFDGYRIMARIDQDEVQLFTRNGHDWTHKLPKQAQALAALGLESAWLDGEMVVADADGVPDFQALQNAFDS
GRSENIVYYLFDLPYLNGVDLREVAVEERRAALATVLKTHQDPLLRFSEAFDETPQALLNSACQMRMEGLIGKRLGSPYV
SRRSSDWIKLKCKHRQEFVIVGYTDPKGARSSFGALLLGLHDRDSGELRYAGKVGTGFNETTLKSILAQLKPLRVKKPAV
ANPPTGFEAKGVHWLKPSLLAEVAFAEMTQDGSVRHAVFHGLREDKPAKDITEERAKPMNTSKTESTAPSQSGLADGKVR
ITHPDRVIDASSGTTKMQLAEYYASVAEWILPQLKDRPVALVRAPDGIAGDLFFQKNAEHLAIPGIRTLDKELTGQPVML
INNAEALIGAVQMSTVELHTWNATTTDLDKPDRFVLDLDPDPALPWKSMIEATALTLTVLDELGLKAFLKTSGGKGIHLV
VPLTRKHGWDEVKDFSHAIVTHMAKLLPERFSAVSGPKNRVGRIFIDYLRNGLGATTICAYAARTREGLPVSVPLFREEV
GEIKGADQWNVHNVHERLAEVGDEPWADIKKTRQSITAEMRKRVGMKK

Sequences:

>Translated_848_residues
MSRNLDDYNRMRDFSATSEPAAGHRRGKKPAGDHALQFCIQKHDASHLHYDFRLELDGALKSWAVPKGPSLDPKVKRLAV
HVEDHPLDYATFEGSIPEGHYGAGDVIVWDRGVWIPLEDPEKAYAKGKLKFELQGEKLAGVWNLVRTHMPGKKEQWFLIK
HQDGAARPQSDYDVLVAEPDSVLSERTIVDKPRLSAKQVKPLQGPAKAPRKSASGKLTGAHKAKIPAQLKPQLATLVESA
PEGDWQYEIKFDGYRIMARIDQDEVQLFTRNGHDWTHKLPKQAQALAALGLESAWLDGEMVVADADGVPDFQALQNAFDS
GRSENIVYYLFDLPYLNGVDLREVAVEERRAALATVLKTHQDPLLRFSEAFDETPQALLNSACQMRMEGLIGKRLGSPYV
SRRSSDWIKLKCKHRQEFVIVGYTDPKGARSSFGALLLGLHDRDSGELRYAGKVGTGFNETTLKSILAQLKPLRVKKPAV
ANPPTGFEAKGVHWLKPSLLAEVAFAEMTQDGSVRHAVFHGLREDKPAKDITEERAKPMNTSKTESTAPSQSGLADGKVR
ITHPDRVIDASSGTTKMQLAEYYASVAEWILPQLKDRPVALVRAPDGIAGDLFFQKNAEHLAIPGIRTLDKELTGQPVML
INNAEALIGAVQMSTVELHTWNATTTDLDKPDRFVLDLDPDPALPWKSMIEATALTLTVLDELGLKAFLKTSGGKGIHLV
VPLTRKHGWDEVKDFSHAIVTHMAKLLPERFSAVSGPKNRVGRIFIDYLRNGLGATTICAYAARTREGLPVSVPLFREEV
GEIKGADQWNVHNVHERLAEVGDEPWADIKKTRQSITAEMRKRVGMKK
>Mature_847_residues
SRNLDDYNRMRDFSATSEPAAGHRRGKKPAGDHALQFCIQKHDASHLHYDFRLELDGALKSWAVPKGPSLDPKVKRLAVH
VEDHPLDYATFEGSIPEGHYGAGDVIVWDRGVWIPLEDPEKAYAKGKLKFELQGEKLAGVWNLVRTHMPGKKEQWFLIKH
QDGAARPQSDYDVLVAEPDSVLSERTIVDKPRLSAKQVKPLQGPAKAPRKSASGKLTGAHKAKIPAQLKPQLATLVESAP
EGDWQYEIKFDGYRIMARIDQDEVQLFTRNGHDWTHKLPKQAQALAALGLESAWLDGEMVVADADGVPDFQALQNAFDSG
RSENIVYYLFDLPYLNGVDLREVAVEERRAALATVLKTHQDPLLRFSEAFDETPQALLNSACQMRMEGLIGKRLGSPYVS
RRSSDWIKLKCKHRQEFVIVGYTDPKGARSSFGALLLGLHDRDSGELRYAGKVGTGFNETTLKSILAQLKPLRVKKPAVA
NPPTGFEAKGVHWLKPSLLAEVAFAEMTQDGSVRHAVFHGLREDKPAKDITEERAKPMNTSKTESTAPSQSGLADGKVRI
THPDRVIDASSGTTKMQLAEYYASVAEWILPQLKDRPVALVRAPDGIAGDLFFQKNAEHLAIPGIRTLDKELTGQPVMLI
NNAEALIGAVQMSTVELHTWNATTTDLDKPDRFVLDLDPDPALPWKSMIEATALTLTVLDELGLKAFLKTSGGKGIHLVV
PLTRKHGWDEVKDFSHAIVTHMAKLLPERFSAVSGPKNRVGRIFIDYLRNGLGATTICAYAARTREGLPVSVPLFREEVG
EIKGADQWNVHNVHERLAEVGDEPWADIKKTRQSITAEMRKRVGMKK

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=353, Percent_Identity=27.4787535410765, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71985269, Length=308, Percent_Identity=30.1948051948052, Blast_Score=89, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320038, Length=350, Percent_Identity=26.2857142857143, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24762424, Length=326, Percent_Identity=26.0736196319018, Blast_Score=84, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 94073; Mature: 93942

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNLDDYNRMRDFSATSEPAAGHRRGKKPAGDHALQFCIQKHDASHLHYDFRLELDGAL
CCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCH
KSWAVPKGPSLDPKVKRLAVHVEDHPLDYATFEGSIPEGHYGAGDVIVWDRGVWIPLEDP
HHCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCCCEEEECCEEEEECCCC
EKAYAKGKLKFELQGEKLAGVWNLVRTHMPGKKEQWFLIKHQDGAARPQSDYDVLVAEPD
HHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCH
SVLSERTIVDKPRLSAKQVKPLQGPAKAPRKSASGKLTGAHKAKIPAQLKPQLATLVESA
HHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
PEGDWQYEIKFDGYRIMARIDQDEVQLFTRNGHDWTHKLPKQAQALAALGLESAWLDGEM
CCCCEEEEEEECCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHCCCCEE
VVADADGVPDFQALQNAFDSGRSENIVYYLFDLPYLNGVDLREVAVEERRAALATVLKTH
EEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHC
QDPLLRFSEAFDETPQALLNSACQMRMEGLIGKRLGSPYVSRRSSDWIKLKCKHRQEFVI
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCEEE
VGYTDPKGARSSFGALLLGLHDRDSGELRYAGKVGTGFNETTLKSILAQLKPLRVKKPAV
EEECCCCCCHHCCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEECCCCC
ANPPTGFEAKGVHWLKPSLLAEVAFAEMTQDGSVRHAVFHGLREDKPAKDITEERAKPMN
CCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCC
TSKTESTAPSQSGLADGKVRITHPDRVIDASSGTTKMQLAEYYASVAEWILPQLKDRPVA
CCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
LVRAPDGIAGDLFFQKNAEHLAIPGIRTLDKELTGQPVMLINNAEALIGAVQMSTVELHT
EEECCCCCEECEEEECCCCEEECCCHHHHHHHHCCCCEEEEECHHHHHEEEEEEEEEEEE
WNATTTDLDKPDRFVLDLDPDPALPWKSMIEATALTLTVLDELGLKAFLKTSGGKGIHLV
CCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCHHEEHCCCCCCEEEEE
VPLTRKHGWDEVKDFSHAIVTHMAKLLPERFSAVSGPKNRVGRIFIDYLRNGLGATTICA
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHH
YAARTREGLPVSVPLFREEVGEIKGADQWNVHNVHERLAEVGDEPWADIKKTRQSITAEM
HHHHCCCCCCEECHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RKRVGMKK
HHHCCCCC
>Mature Secondary Structure 
SRNLDDYNRMRDFSATSEPAAGHRRGKKPAGDHALQFCIQKHDASHLHYDFRLELDGAL
CCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCH
KSWAVPKGPSLDPKVKRLAVHVEDHPLDYATFEGSIPEGHYGAGDVIVWDRGVWIPLEDP
HHCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCCCEEEECCEEEEECCCC
EKAYAKGKLKFELQGEKLAGVWNLVRTHMPGKKEQWFLIKHQDGAARPQSDYDVLVAEPD
HHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCH
SVLSERTIVDKPRLSAKQVKPLQGPAKAPRKSASGKLTGAHKAKIPAQLKPQLATLVESA
HHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
PEGDWQYEIKFDGYRIMARIDQDEVQLFTRNGHDWTHKLPKQAQALAALGLESAWLDGEM
CCCCEEEEEEECCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHCCCCEE
VVADADGVPDFQALQNAFDSGRSENIVYYLFDLPYLNGVDLREVAVEERRAALATVLKTH
EEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHC
QDPLLRFSEAFDETPQALLNSACQMRMEGLIGKRLGSPYVSRRSSDWIKLKCKHRQEFVI
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCEEE
VGYTDPKGARSSFGALLLGLHDRDSGELRYAGKVGTGFNETTLKSILAQLKPLRVKKPAV
EEECCCCCCHHCCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEECCCCC
ANPPTGFEAKGVHWLKPSLLAEVAFAEMTQDGSVRHAVFHGLREDKPAKDITEERAKPMN
CCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCC
TSKTESTAPSQSGLADGKVRITHPDRVIDASSGTTKMQLAEYYASVAEWILPQLKDRPVA
CCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
LVRAPDGIAGDLFFQKNAEHLAIPGIRTLDKELTGQPVMLINNAEALIGAVQMSTVELHT
EEECCCCCEECEEEECCCCEEECCCHHHHHHHHCCCCEEEEECHHHHHEEEEEEEEEEEE
WNATTTDLDKPDRFVLDLDPDPALPWKSMIEATALTLTVLDELGLKAFLKTSGGKGIHLV
CCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCHHEEHCCCCCCEEEEE
VPLTRKHGWDEVKDFSHAIVTHMAKLLPERFSAVSGPKNRVGRIFIDYLRNGLGATTICA
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHH
YAARTREGLPVSVPLFREEVGEIKGADQWNVHNVHERLAEVGDEPWADIKKTRQSITAEM
HHHHCCCCCCEECHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RKRVGMKK
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]