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The map label for this gene is mtnC

Identifier: 77457953

GI number: 77457953

Start: 1919103

End: 1919786

Strand: Direct

Name: mtnC

Synonym: Pfl01_1726

Alternate gene names: 77457953

Gene position: 1919103-1919786 (Clockwise)

Preceding gene: 77457952

Following gene: 77457955

Centisome position: 29.81

GC content: 60.09

Gene sequence:

>684_bases
ATGTCGATCAAGGTCATTCTCACCGACATCGAAGGCACCACCAGCGCGGTGAGTTTTGTGTTCGACGTGCTGTTCCCATA
TGCCGCCAAACACCTGCCGGACTTCGTCCGTCAGAACGCCCAGCGCGCCGACGTTGCCGAGCAACTGGATGCCGTGCGCC
GCGACAGCAACGAACCGCAGGCTGACGTCGAGCGAGTCGTGGAAATTCTGCTGGCCTGGATCGCCGAAGACCGCAAAGCC
ACGCCGCTGAAAGCGTTGCAAGGCATGGTCTGGGAGCAGGGTTATCAGGCCGGGCAGTTGAAAGGCCATGTTTACCCGGA
CGCTGTTGAAGCGCTCCAGCGCTGGCATCAGGCCGGTTATCAACTTTTTGTTTATTCGTCCGGTTCGATCCAGGCGCAGA
AGCTGATTTTCGGCTGCTCGGAAGCAGGAGATCTGACGCCGTTGTTCAGTGGCTACTTCGACACCACGTCGGGCCCCAAG
CGCGAGCCGCAGTCATATACCAATATCCAGCAGGCCATCGGAGTCGAACCGCAGGAAATCCTGTTCCTCTCCGACATCGT
CCAGGAACTCGACGCCGCCCAGTCAGCCGGCCTGCAAACCTGCGGCCTGGCTCGTGAGGGCGGGGAGCTGGAAGGTCATG
TGACCGTCGACAGCTTCACTGGGATCGAACCCGAAGCGTTCTGA

Upstream 100 bases:

>100_bases
TTTCGTGGCGATCCGTCTGTTCAACAACCCTGAAGGCTGGGTCGCCAACTTCACCGGCGAAGACATCGCCGGTCGCTTCC
CGCGTCTGGAGGACTGAGCG

Downstream 100 bases:

>100_bases
GTTCACACAATCGCCGCGCAAAAAAACAGGCCGTGAAGCGAAAGCTCCACGGCCTGTCTGTTTATACGGTGTTCGAATTA
CATCGAGTGATAAGTCGGCA

Product: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSIKVILTDIEGTTSAVSFVFDVLFPYAAKHLPDFVRQNAQRADVAEQLDAVRRDSNEPQADVERVVEILLAWIAEDRKA
TPLKALQGMVWEQGYQAGQLKGHVYPDAVEALQRWHQAGYQLFVYSSGSIQAQKLIFGCSEAGDLTPLFSGYFDTTSGPK
REPQSYTNIQQAIGVEPQEILFLSDIVQELDAAQSAGLQTCGLAREGGELEGHVTVDSFTGIEPEAF

Sequences:

>Translated_227_residues
MSIKVILTDIEGTTSAVSFVFDVLFPYAAKHLPDFVRQNAQRADVAEQLDAVRRDSNEPQADVERVVEILLAWIAEDRKA
TPLKALQGMVWEQGYQAGQLKGHVYPDAVEALQRWHQAGYQLFVYSSGSIQAQKLIFGCSEAGDLTPLFSGYFDTTSGPK
REPQSYTNIQQAIGVEPQEILFLSDIVQELDAAQSAGLQTCGLAREGGELEGHVTVDSFTGIEPEAF
>Mature_226_residues
SIKVILTDIEGTTSAVSFVFDVLFPYAAKHLPDFVRQNAQRADVAEQLDAVRRDSNEPQADVERVVEILLAWIAEDRKAT
PLKALQGMVWEQGYQAGQLKGHVYPDAVEALQRWHQAGYQLFVYSSGSIQAQKLIFGCSEAGDLTPLFSGYFDTTSGPKR
EPQSYTNIQQAIGVEPQEILFLSDIVQELDAAQSAGLQTCGLAREGGELEGHVTVDSFTGIEPEAF

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family

Homologues:

Organism=Homo sapiens, GI10864017, Length=226, Percent_Identity=34.9557522123894, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI115533232, Length=242, Percent_Identity=38.8429752066116, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6320797, Length=212, Percent_Identity=41.5094339622642, Blast_Score=145, Evalue=6e-36,
Organism=Drosophila melanogaster, GI281360080, Length=216, Percent_Identity=46.2962962962963, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24644163, Length=216, Percent_Identity=46.2962962962963, Blast_Score=187, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNC_PSEPF (Q3KFI7)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_347458.1
- HSSP:   P32626
- ProteinModelPortal:   Q3KFI7
- SMR:   Q3KFI7
- STRING:   Q3KFI7
- GeneID:   3716677
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_1726
- eggNOG:   COG4229
- HOGENOM:   HBG294242
- OMA:   TTDLNFI
- ProtClustDB:   CLSK866737
- BioCyc:   PFLU205922:PFL_1726-MONOMER
- HAMAP:   MF_01681
- InterPro:   IPR005834
- InterPro:   IPR010041
- InterPro:   IPR023214
- InterPro:   IPR005833
- Gene3D:   G3DSA:3.40.50.1000
- PANTHER:   PTHR20371
- PRINTS:   PR00413
- TIGRFAMs:   TIGR01691

Pfam domain/function: PF00702 Hydrolase; SSF56784 SSF56784

EC number: =3.1.3.77

Molecular weight: Translated: 24939; Mature: 24808

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKVILTDIEGTTSAVSFVFDVLFPYAAKHLPDFVRQNAQRADVAEQLDAVRRDSNEPQ
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCH
ADVERVVEILLAWIAEDRKATPLKALQGMVWEQGYQAGQLKGHVYPDAVEALQRWHQAGY
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
QLFVYSSGSIQAQKLIFGCSEAGDLTPLFSGYFDTTSGPKREPQSYTNIQQAIGVEPQEI
EEEEEECCCCCHHHHHEECCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHH
LFLSDIVQELDAAQSAGLQTCGLAREGGELEGHVTVDSFTGIEPEAF
HHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SIKVILTDIEGTTSAVSFVFDVLFPYAAKHLPDFVRQNAQRADVAEQLDAVRRDSNEPQ
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCH
ADVERVVEILLAWIAEDRKATPLKALQGMVWEQGYQAGQLKGHVYPDAVEALQRWHQAGY
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
QLFVYSSGSIQAQKLIFGCSEAGDLTPLFSGYFDTTSGPKREPQSYTNIQQAIGVEPQEI
EEEEEECCCCCHHHHHEECCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHH
LFLSDIVQELDAAQSAGLQTCGLAREGGELEGHVTVDSFTGIEPEAF
HHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA