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The map label for this gene is mtnD [H]

Identifier: 77457952

GI number: 77457952

Start: 1918494

End: 1919099

Strand: Direct

Name: mtnD [H]

Synonym: Pfl01_1725

Alternate gene names: 77457952

Gene position: 1918494-1919099 (Clockwise)

Preceding gene: 77457951

Following gene: 77457953

Centisome position: 29.8

GC content: 59.08

Gene sequence:

>606_bases
ATGCAGTGCCCGACCGGTCTCGAAGAACCGGACGGCAAGGCCGATACCGAGGAATGCCCCATGAGCAGCCTGTCCGTCTA
TCACGTTTCCAGCCCCGAGATTCCGAACAAGGTGCTGACCCATTTCGAAGACATCGCTTCGACCCTGGCCGAGCAGGGCG
TGCGCTTCGACCGTTGGCAAGCCGCCGCGAAGATCCAGCCCGGCGCCAGCCAGGAAGAAGTGATCGGTGCTTATAAAGAG
CAGATCGACAAACTGATGACTGAGCGCGGCTACATCACGGTCGACGTGATCAGCCTCAACAGCGACCACCCACAAAAAGC
CGAATTGCGCGCCAAGTTCCTCGAAGAACATCGGCATGGCGAAGACGAAGTACGCTTCTTCGTTGCCGGTCGCGGTCTGT
TTACCCTGCACATCGACGATTACGTCTACGCCGTGCTGTGCGAGAAGAACGACCTGATTTCGGTGCCGGCCGGTACCAAG
CATTGGTTCGATATGGGCGAGAACCCGCATTTCGTGGCGATCCGTCTGTTCAACAACCCTGAAGGCTGGGTCGCCAACTT
CACCGGCGAAGACATCGCCGGTCGCTTCCCGCGTCTGGAGGACTGA

Upstream 100 bases:

>100_bases
ATCGAGGCCTTTGAATTCCTGTTTGAATGCGAGTTGAAGACCCGCAGCGTCATGAACCGCCAAGGCTGACTTCACCAGAA
CCAGCCCCTTTGCCCGATGA

Downstream 100 bases:

>100_bases
GCGATGTCGATCAAGGTCATTCTCACCGACATCGAAGGCACCACCAGCGCGGTGAGTTTTGTGTTCGACGTGCTGTTCCC
ATATGCCGCCAAACACCTGC

Product: acireductone dioxygenase, ARD

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MQCPTGLEEPDGKADTEECPMSSLSVYHVSSPEIPNKVLTHFEDIASTLAEQGVRFDRWQAAAKIQPGASQEEVIGAYKE
QIDKLMTERGYITVDVISLNSDHPQKAELRAKFLEEHRHGEDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTK
HWFDMGENPHFVAIRLFNNPEGWVANFTGEDIAGRFPRLED

Sequences:

>Translated_201_residues
MQCPTGLEEPDGKADTEECPMSSLSVYHVSSPEIPNKVLTHFEDIASTLAEQGVRFDRWQAAAKIQPGASQEEVIGAYKE
QIDKLMTERGYITVDVISLNSDHPQKAELRAKFLEEHRHGEDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTK
HWFDMGENPHFVAIRLFNNPEGWVANFTGEDIAGRFPRLED
>Mature_201_residues
MQCPTGLEEPDGKADTEECPMSSLSVYHVSSPEIPNKVLTHFEDIASTLAEQGVRFDRWQAAAKIQPGASQEEVIGAYKE
QIDKLMTERGYITVDVISLNSDHPQKAELRAKFLEEHRHGEDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTK
HWFDMGENPHFVAIRLFNNPEGWVANFTGEDIAGRFPRLED

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family [H]

Homologues:

Organism=Homo sapiens, GI171460928, Length=107, Percent_Identity=33.6448598130841, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710 [H]

Pfam domain/function: PF03079 ARD [H]

EC number: =1.13.11.54; =1.13.11.53 [H]

Molecular weight: Translated: 22679; Mature: 22679

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCPTGLEEPDGKADTEECPMSSLSVYHVSSPEIPNKVLTHFEDIASTLAEQGVRFDRWQ
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
AAAKIQPGASQEEVIGAYKEQIDKLMTERGYITVDVISLNSDHPQKAELRAKFLEEHRHG
HHEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCC
EDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTKHWFDMGENPHFVAIRLFNNP
CCCEEEEEECCCEEEEEECCEEEEEEECCCCEEECCCCCCHHHCCCCCCCEEEEEEEECC
EGWVANFTGEDIAGRFPRLED
CCEEEECCCCCHHCCCCCCCC
>Mature Secondary Structure
MQCPTGLEEPDGKADTEECPMSSLSVYHVSSPEIPNKVLTHFEDIASTLAEQGVRFDRWQ
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
AAAKIQPGASQEEVIGAYKEQIDKLMTERGYITVDVISLNSDHPQKAELRAKFLEEHRHG
HHEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCC
EDEVRFFVAGRGLFTLHIDDYVYAVLCEKNDLISVPAGTKHWFDMGENPHFVAIRLFNNP
CCCEEEEEECCCEEEEEECCEEEEEEECCCCEEECCCCCCHHHCCCCCCCEEEEEEEECC
EGWVANFTGEDIAGRFPRLED
CCEEEECCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA