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The map label for this gene is mtnB

Identifier: 77457951

GI number: 77457951

Start: 1917836

End: 1918462

Strand: Direct

Name: mtnB

Synonym: Pfl01_1724

Alternate gene names: 77457951

Gene position: 1917836-1918462 (Clockwise)

Preceding gene: 77457950

Following gene: 77457952

Centisome position: 29.79

GC content: 62.2

Gene sequence:

>627_bases
ATGAGCCTTACCCGTGAACAGCTTGCCCAGCAAATTGTCGACGCCGGGCGTTTTCTTTATGGTCGCGGCTGGTCGCCGGC
CACCAGCAGCAATTACTCGACGCGCCTGTCGCCGAGCGAAGCGCTGCTGACCGTGTCCGGCAAGCACAAGGGCCAGTTGG
GCCTGGACGACGTGCTCGCCACCGATCTGTCCGGCAACAGCCTGGAACCCGGCAAAAAACCGTCCGCCGAAACCCTGCTG
CACACCCAGCTCTACAGCTGGCGGCCGGAAATCGGCGCGGTGTTGCACACCCACTCGGTGAACGCCACGGTGCTGTCGCG
CCTGACGCCGCAAGACTTCATCGAGTTCGAAGACTACGAACTGCAAAAAGCCTTCAGCGGCGTCTCGACCCACGAATCCC
GGGTGCGCGTGCCGATCTTCGACAACGATCAGGACATTGCACGCCTCGCTGCCAAGGTGCAGCCTTGGCTCGAGGCCCAT
CCCGATTGCGTGGGTTATCTGATTCGCGGCCACGGCCTCTACACCTGGGGCGCGCAGATGAGCGACGCGTTGCGCCAGAT
CGAGGCCTTTGAATTCCTGTTTGAATGCGAGTTGAAGACCCGCAGCGTCATGAACCGCCAAGGCTGA

Upstream 100 bases:

>100_bases
GCTGGAATGCCCTCGGCGCGACATTGACCTTTAGTATTGCCAGTCTCGCAGCGCTCGCCGCTGCCGTTATCATTGCCATT
CGAATGCAAGAGGACAGGCC

Downstream 100 bases:

>100_bases
CTTCACCAGAACCAGCCCCTTTGCCCGATGAATGCAGTGCCCGACCGGTCTCGAAGAACCGGACGGCAAGGCCGATACCG
AGGAATGCCCCATGAGCAGC

Product: methylthioribulose-1-phosphate dehydratase

Products: NA

Alternate protein names: MTRu-1-P dehydratase

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSLTREQLAQQIVDAGRFLYGRGWSPATSSNYSTRLSPSEALLTVSGKHKGQLGLDDVLATDLSGNSLEPGKKPSAETLL
HTQLYSWRPEIGAVLHTHSVNATVLSRLTPQDFIEFEDYELQKAFSGVSTHESRVRVPIFDNDQDIARLAAKVQPWLEAH
PDCVGYLIRGHGLYTWGAQMSDALRQIEAFEFLFECELKTRSVMNRQG

Sequences:

>Translated_208_residues
MSLTREQLAQQIVDAGRFLYGRGWSPATSSNYSTRLSPSEALLTVSGKHKGQLGLDDVLATDLSGNSLEPGKKPSAETLL
HTQLYSWRPEIGAVLHTHSVNATVLSRLTPQDFIEFEDYELQKAFSGVSTHESRVRVPIFDNDQDIARLAAKVQPWLEAH
PDCVGYLIRGHGLYTWGAQMSDALRQIEAFEFLFECELKTRSVMNRQG
>Mature_207_residues
SLTREQLAQQIVDAGRFLYGRGWSPATSSNYSTRLSPSEALLTVSGKHKGQLGLDDVLATDLSGNSLEPGKKPSAETLLH
TQLYSWRPEIGAVLHTHSVNATVLSRLTPQDFIEFEDYELQKAFSGVSTHESRVRVPIFDNDQDIARLAAKVQPWLEAHP
DCVGYLIRGHGLYTWGAQMSDALRQIEAFEFLFECELKTRSVMNRQG

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily

Homologues:

Organism=Homo sapiens, GI166235186, Length=195, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18859685, Length=196, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNB_PSEPF (Q3KFI9)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_347456.1
- ProteinModelPortal:   Q3KFI9
- STRING:   Q3KFI9
- GeneID:   3716675
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_1724
- eggNOG:   COG0235
- HOGENOM:   HBG337716
- OMA:   EFLFECE
- ProtClustDB:   PRK09220
- BioCyc:   PFLU205922:PFL_1724-MONOMER
- HAMAP:   MF_01677
- InterPro:   IPR001303
- InterPro:   IPR017714
- Gene3D:   G3DSA:3.40.225.10
- TIGRFAMs:   TIGR03328

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: =4.2.1.109

Molecular weight: Translated: 23235; Mature: 23104

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTREQLAQQIVDAGRFLYGRGWSPATSSNYSTRLSPSEALLTVSGKHKGQLGLDDVLA
CCCCHHHHHHHHHHHCCEEECCCCCCCCCCCCCEECCCCCEEEEECCCCCCCCCHHHHHH
TDLSGNSLEPGKKPSAETLLHTQLYSWRPEIGAVLHTHSVNATVLSRLTPQDFIEFEDYE
HCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHEEEECCCCHHHHHHCCHHHHHCCCCHH
LQKAFSGVSTHESRVRVPIFDNDQDIARLAAKVQPWLEAHPDCVGYLIRGHGLYTWGAQM
HHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCHHH
SDALRQIEAFEFLFECELKTRSVMNRQG
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLTREQLAQQIVDAGRFLYGRGWSPATSSNYSTRLSPSEALLTVSGKHKGQLGLDDVLA
CCCHHHHHHHHHHHCCEEECCCCCCCCCCCCCEECCCCCEEEEECCCCCCCCCHHHHHH
TDLSGNSLEPGKKPSAETLLHTQLYSWRPEIGAVLHTHSVNATVLSRLTPQDFIEFEDYE
HCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHEEEECCCCHHHHHHCCHHHHHCCCCHH
LQKAFSGVSTHESRVRVPIFDNDQDIARLAAKVQPWLEAHPDCVGYLIRGHGLYTWGAQM
HHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCHHH
SDALRQIEAFEFLFECELKTRSVMNRQG
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA