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The map label for this gene is hcaT [H]

Identifier: 77457950

GI number: 77457950

Start: 1916694

End: 1917839

Strand: Direct

Name: hcaT [H]

Synonym: Pfl01_1723

Alternate gene names: 77457950

Gene position: 1916694-1917839 (Clockwise)

Preceding gene: 77457949

Following gene: 77457951

Centisome position: 29.77

GC content: 62.13

Gene sequence:

>1146_bases
GTGGCGGCGCTCCCGTACTGGCGGCTGTCCAGTTTCTATCTGTTCTATTTCGCCTTGCTCGGTTCGACGGCGCCGTTTCT
GGCGCTGTACTTCGATCACCTCGGTTTCAGTGCCGCGCGGATCGGCGAACTGGTGGCGATCCCGATGCTGATGCGCTGCG
TAGCACCGAACATCTGGGGTTGGCTTGGCGATTACACCGGCAGGCGCCTGGCCATCGTGCGCTTCGGCGCGGTGTGCACG
CTGCTGACGTTCTCATTGATTTTCGTCAGCAAGACCTACGCCTGGCTGGCGATGGTCATGGCCTTGCACGCGTTTTTCTG
GCACGCGGTGCTGCCGCAGTTCGAAGTCATCACTCTGGCGCATTTGCAGGGCCAGACCTCCCGCTACAGTCAGATTCGCC
TGTGGGGCTCGATCGGTTTCATCATCACCGTGGTCGCCCTCGGTCGCCTGTTCGAATGGCTCAGCCTCGACATCTACCCG
GCGGCGCTGGTGTTGATCATGGCCGGCATCGTCCTCAGCAGTCTGTGGGTGCCGAATGCGCAACCGCCTCAGGGCAACCG
TCCGACGGGCGAGGGCTTTCTCAAACAGTTGCGCAATCCCGGGGTGCTGGCGTTTTACGGTTGCGTGGCGCTGATGCAGA
TGAGTCACGGGCCGTATTACACGTTTTTGACCCTGCACCTCGAACGACTGGGCTACAGCCGCGGCGTGATCGGCATGCTC
TGGGCGGTCGGCGTGGTGGCGGAAGTGCTGATGTTCATGGCCATGAGCCGGATCCTCGCGCGTTTTTCCCTGCGGCGGGT
GTTGATGGCGAGTTTTCTGCTGGCGGCGTTGCGCTGGTTGCTGCTAGGTTCGTTCGCCGAGTTCCTGTGGGTCTTGCTGT
TTGCCCAGGTGCTGCACGCGGCGACGTTCGGCAGCTTTCATGCGGCTGCCATCGCGTTCGTGCAACGTAGCTTCGGCGCG
CGTCAGCAAGGGCAGGGTCAGGCGTTGTATGCCGCGCTGGCTGGCACCGGTGGTGCGCTCGGCGCGTTGTATTCCGGCTA
CAGCTGGAATGCCCTCGGCGCGACATTGACCTTTAGTATTGCCAGTCTCGCAGCGCTCGCCGCTGCCGTTATCATTGCCA
TTCGAATGCAAGAGGACAGGCCATGA

Upstream 100 bases:

>100_bases
CACCTGCTGCGCCACCGTGGCCAGAACGCCGATGTGCGCGTGAGCACCCCGGTGCTGGGTCAGCTTTGATGGGTGATCTC
AAAGCCGCCGCGGTCTGACC

Downstream 100 bases:

>100_bases
GCCTTACCCGTGAACAGCTTGCCCAGCAAATTGTCGACGCCGGGCGTTTTCTTTATGGTCGCGGCTGGTCGCCGGCCACC
AGCAGCAATTACTCGACGCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MAALPYWRLSSFYLFYFALLGSTAPFLALYFDHLGFSAARIGELVAIPMLMRCVAPNIWGWLGDYTGRRLAIVRFGAVCT
LLTFSLIFVSKTYAWLAMVMALHAFFWHAVLPQFEVITLAHLQGQTSRYSQIRLWGSIGFIITVVALGRLFEWLSLDIYP
AALVLIMAGIVLSSLWVPNAQPPQGNRPTGEGFLKQLRNPGVLAFYGCVALMQMSHGPYYTFLTLHLERLGYSRGVIGML
WAVGVVAEVLMFMAMSRILARFSLRRVLMASFLLAALRWLLLGSFAEFLWVLLFAQVLHAATFGSFHAAAIAFVQRSFGA
RQQGQGQALYAALAGTGGALGALYSGYSWNALGATLTFSIASLAALAAAVIIAIRMQEDRP

Sequences:

>Translated_381_residues
MAALPYWRLSSFYLFYFALLGSTAPFLALYFDHLGFSAARIGELVAIPMLMRCVAPNIWGWLGDYTGRRLAIVRFGAVCT
LLTFSLIFVSKTYAWLAMVMALHAFFWHAVLPQFEVITLAHLQGQTSRYSQIRLWGSIGFIITVVALGRLFEWLSLDIYP
AALVLIMAGIVLSSLWVPNAQPPQGNRPTGEGFLKQLRNPGVLAFYGCVALMQMSHGPYYTFLTLHLERLGYSRGVIGML
WAVGVVAEVLMFMAMSRILARFSLRRVLMASFLLAALRWLLLGSFAEFLWVLLFAQVLHAATFGSFHAAAIAFVQRSFGA
RQQGQGQALYAALAGTGGALGALYSGYSWNALGATLTFSIASLAALAAAVIIAIRMQEDRP
>Mature_380_residues
AALPYWRLSSFYLFYFALLGSTAPFLALYFDHLGFSAARIGELVAIPMLMRCVAPNIWGWLGDYTGRRLAIVRFGAVCTL
LTFSLIFVSKTYAWLAMVMALHAFFWHAVLPQFEVITLAHLQGQTSRYSQIRLWGSIGFIITVVALGRLFEWLSLDIYPA
ALVLIMAGIVLSSLWVPNAQPPQGNRPTGEGFLKQLRNPGVLAFYGCVALMQMSHGPYYTFLTLHLERLGYSRGVIGMLW
AVGVVAEVLMFMAMSRILARFSLRRVLMASFLLAALRWLLLGSFAEFLWVLLFAQVLHAATFGSFHAAAIAFVQRSFGAR
QQGQGQALYAALAGTGGALGALYSGYSWNALGATLTFSIASLAALAAAVIIAIRMQEDRP

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=370, Percent_Identity=29.1891891891892, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788415, Length=331, Percent_Identity=24.1691842900302, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 41935; Mature: 41804

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AALPYWRLSSFYLFYFALLGSTAPFLALYFDHLGFSAARIGELVAIPMLMRCVAPNIWG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHH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HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]