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The map label for this gene is aroC [H]

Identifier: 77457949

GI number: 77457949

Start: 1915571

End: 1916662

Strand: Direct

Name: aroC [H]

Synonym: Pfl01_1722

Alternate gene names: 77457949

Gene position: 1915571-1916662 (Clockwise)

Preceding gene: 77457946

Following gene: 77457950

Centisome position: 29.75

GC content: 64.1

Gene sequence:

>1092_bases
ATGTCCGGCAATACCTACGGCAAGCTGTTCACTGTCACCACCGCGGGCGAAAGCCATGGTCCGGCGTTGGTCGCCATTGT
CGACGGCTGCCCGCCGGGCCTGGAGATTTCCCTTGAAGATCTGCAACGCGACCTCGACCGTCGCAAGCCGGGCACCAGCC
GCCACACCACCCAGCGCCAGGAAGCCGACGAAGTCGAAATCCTTTCCGGCGTGTTCGAGGGCCGCACCACCGGCTGCTCC
ATTGGCCTGCTGATTCGCAACACCGACCAGAAGTCCAAGGACTACTCGGCGATCAAGGACCTGTTCCGCCCGGCCCACGC
CGACTACACCTACCACCACAAATACGGCGAGCGCGATTATCGCGGCGGCGGTCGCAGCTCCGCGCGGGAAACCGCCATGC
GCGTCGCGGCTGGCGCCATCGCCAAGAAGTACCTGGCCAGCCAAGGCATCGTCATTCGCGGCTACATGAGCCAGCTCGGC
CCGATCGAAATCCCGTTCAAGACCTGGGAATCGGTCGAGCAGAATGCCTTCTTCAGCCCGGACCCGGACAAAGTGCCGGA
GCTGGAAGCTTATATGGATCAGTTGCGCCGCGATCAGGATTCCGTCGGGGCGAAGATCACCGTGGTTGCCGAAGGCGTGA
TGCCGGGCCTGGGCGAGCCGATCTTCGACCGTCTCGATGCCGAACTGGCCCATGCGCTGATGAGCATCAACGCGGTCAAA
GGTGTGGAAATCGGCGCCGGTTTCGCCTGCGTCGCCCAGCGCGGCACCGAACACCGTGACGAGCTGACCCCGGAAGGTTT
CCTCAGCAACAACGCGGGCGGCATCCTTGGCGGGATCTCTTCGGGGCAGCCGATCGTCGCGCACCTGGCCTTGAAGCCGA
CCTCGAGCATCACCACCCCGGGCCGTTCGATCGACATCGATGGCAACCCGGTCGATGTCATTACCAAGGGCCGTCACGAC
CCATGTGTCGGTATCCGCGCCACGCCGATTGCCGAGGCGATGATGGCCATCGTGTTGATGGATCACCTGCTGCGCCACCG
TGGCCAGAACGCCGATGTGCGCGTGAGCACCCCGGTGCTGGGTCAGCTTTGA

Upstream 100 bases:

>100_bases
ACTCACCCGCACCGCTAAGGTTCGAGGATGAACTACTCGGTTAGCCTGCGTATACTGGCGCGCATCACGAATCTGGGTTC
GATTTCACGGAGCGTCCTGC

Downstream 100 bases:

>100_bases
TGGGTGATCTCAAAGCCGCCGCGGTCTGACCGTGGCGGCGCTCCCGTACTGGCGGCTGTCCAGTTTCTATCTGTTCTATT
TCGCCTTGCTCGGTTCGACG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSGNTYGKLFTVTTAGESHGPALVAIVDGCPPGLEISLEDLQRDLDRRKPGTSRHTTQRQEADEVEILSGVFEGRTTGCS
IGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGERDYRGGGRSSARETAMRVAAGAIAKKYLASQGIVIRGYMSQLG
PIEIPFKTWESVEQNAFFSPDPDKVPELEAYMDQLRRDQDSVGAKITVVAEGVMPGLGEPIFDRLDAELAHALMSINAVK
GVEIGAGFACVAQRGTEHRDELTPEGFLSNNAGGILGGISSGQPIVAHLALKPTSSITTPGRSIDIDGNPVDVITKGRHD
PCVGIRATPIAEAMMAIVLMDHLLRHRGQNADVRVSTPVLGQL

Sequences:

>Translated_363_residues
MSGNTYGKLFTVTTAGESHGPALVAIVDGCPPGLEISLEDLQRDLDRRKPGTSRHTTQRQEADEVEILSGVFEGRTTGCS
IGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGERDYRGGGRSSARETAMRVAAGAIAKKYLASQGIVIRGYMSQLG
PIEIPFKTWESVEQNAFFSPDPDKVPELEAYMDQLRRDQDSVGAKITVVAEGVMPGLGEPIFDRLDAELAHALMSINAVK
GVEIGAGFACVAQRGTEHRDELTPEGFLSNNAGGILGGISSGQPIVAHLALKPTSSITTPGRSIDIDGNPVDVITKGRHD
PCVGIRATPIAEAMMAIVLMDHLLRHRGQNADVRVSTPVLGQL
>Mature_362_residues
SGNTYGKLFTVTTAGESHGPALVAIVDGCPPGLEISLEDLQRDLDRRKPGTSRHTTQRQEADEVEILSGVFEGRTTGCSI
GLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGERDYRGGGRSSARETAMRVAAGAIAKKYLASQGIVIRGYMSQLGP
IEIPFKTWESVEQNAFFSPDPDKVPELEAYMDQLRRDQDSVGAKITVVAEGVMPGLGEPIFDRLDAELAHALMSINAVKG
VEIGAGFACVAQRGTEHRDELTPEGFLSNNAGGILGGISSGQPIVAHLALKPTSSITTPGRSIDIDGNPVDVITKGRHDP
CVGIRATPIAEAMMAIVLMDHLLRHRGQNADVRVSTPVLGQL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=71.5877437325905, Blast_Score=498, Evalue=1e-142,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=41.0326086956522, Blast_Score=270, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39097; Mature: 38966

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNTYGKLFTVTTAGESHGPALVAIVDGCPPGLEISLEDLQRDLDRRKPGTSRHTTQRQ
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCCCCCHHH
EADEVEILSGVFEGRTTGCSIGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGERDY
HHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLASQGIVIRGYMSQLGPIEIPFKTWESVEQNAFFSP
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCEECCHHHHHHHHHCCCCCC
DPDKVPELEAYMDQLRRDQDSVGAKITVVAEGVMPGLGEPIFDRLDAELAHALMSINAVK
CCCCCCHHHHHHHHHHCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GVEIGAGFACVAQRGTEHRDELTPEGFLSNNAGGILGGISSGQPIVAHLALKPTSSITTP
CEECCCCHHHHHHCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCC
GRSIDIDGNPVDVITKGRHDPCVGIRATPIAEAMMAIVLMDHLLRHRGQNADVRVSTPVL
CCEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHH
GQL
CCC
>Mature Secondary Structure 
SGNTYGKLFTVTTAGESHGPALVAIVDGCPPGLEISLEDLQRDLDRRKPGTSRHTTQRQ
CCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCCCCCHHH
EADEVEILSGVFEGRTTGCSIGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGERDY
HHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLASQGIVIRGYMSQLGPIEIPFKTWESVEQNAFFSP
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCEECCHHHHHHHHHCCCCCC
DPDKVPELEAYMDQLRRDQDSVGAKITVVAEGVMPGLGEPIFDRLDAELAHALMSINAVK
CCCCCCHHHHHHHHHHCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GVEIGAGFACVAQRGTEHRDELTPEGFLSNNAGGILGGISSGQPIVAHLALKPTSSITTP
CEECCCCHHHHHHCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCC
GRSIDIDGNPVDVITKGRHDPCVGIRATPIAEAMMAIVLMDHLLRHRGQNADVRVSTPVL
CCEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHH
GQL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA