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The map label for this gene is yocS [H]

Identifier: 77457894

GI number: 77457894

Start: 1858496

End: 1859461

Strand: Reverse

Name: yocS [H]

Synonym: Pfl01_1667

Alternate gene names: 77457894

Gene position: 1859461-1858496 (Counterclockwise)

Preceding gene: 77457895

Following gene: 77457893

Centisome position: 28.88

GC content: 63.98

Gene sequence:

>966_bases
ATGCGCGCACTGGCTGCACTGAGTCGTTTTGTCGGCAATACCTTCGCTTACTGGGTTCTGATTTTCGCGGTGATCGCGTT
CCTGCAACCGGCCTGGTTCCTCGGTCTGAAAGGCGCGATCGTGCCACTGCTCGGGCTGGTGATGTTCGGCATGGGCCTGA
CCCTCAAGCTCGACGACTTCGCCGCCGTCGCCCGCCATCCGTGGCGTGTGGCGCTGGGGGTCGTCGCGCATTTCGTGATC
ATGCCGGGGATGGCGTGGCTGCTGTGCCAGATCTTTCATTTGCCGCCGGAAATCGCCGTCGGCGTGATTCTGGTCGGTTG
CTGCCCGAGCGGCACCTCCTCGAACGTCATGACCTGGCTGGCCCGTGGCGACCTGGCGCTGTCGGTGGCGATCGCCGCCG
TCACCACCCTCCTCGCCCCGTTGCTGACGCCGGCGCTGATCTGGCTGCTGGCCTCGGCCTGGTTGCCGGTTTCGTTCATG
GAATTGTTCTGGTCGATCCTGCAAGTGGTGCTGCTGCCGATCGTCCTCGGCGTGGTCGCGCAACGTGTGCTCGGTGACAA
GGTGCGCCACGCGGTGGAAGTGTTGCCGCTGGTGTCGGTGATCAGCATCGTGATCATCGTCGCCGCCGTGGTTGCCGCCA
GTCAGGCAAAAATCGCCGAATCCGGCCTGCTGATCATGGCCGTGGTGATGCTGCACAACAGCTTCGGCTATTTGCTGGGT
TATTTCACCGGGCGCCTGTTCGGCCTGCCGCTGCCGCAGCGCAAGTCCCTGGCGCTGGAAGTCGGCATGCAGAACTCGGG
GTTGGGGGCTGCGCTGGCCAGTGCGCACTTCTCGCCGCTGGCGGCGGTGCCGAGCGCGTTGTTCAGTGTGTGGCACAACA
TTTCCGGGGCACTGCTTTCGACGTACTTCCGGCGGATGAGCGAAAAACAAGACAGTGAAACGCTGGCGCAACAGGCGGCC
GACTGA

Upstream 100 bases:

>100_bases
GCGAAGAGACACCGCAGGGGATCTAAGCCTCTGCGCAGTCTTTGGGTTATCTTCAAACGCCACCGCTTCGGTGGCGTTTT
CACATAATAAGGAACAGGCC

Downstream 100 bases:

>100_bases
TTCCGGATCGCGGTGCGGCGCACATTTTTAGGTAGTATGTGCGCCACGCGGGGACGACCCTGCGGCTCAATCGAGTTTTC
AATCTGGGGACGGCCCCGTC

Product: bile acid:sodium symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MRALAALSRFVGNTFAYWVLIFAVIAFLQPAWFLGLKGAIVPLLGLVMFGMGLTLKLDDFAAVARHPWRVALGVVAHFVI
MPGMAWLLCQIFHLPPEIAVGVILVGCCPSGTSSNVMTWLARGDLALSVAIAAVTTLLAPLLTPALIWLLASAWLPVSFM
ELFWSILQVVLLPIVLGVVAQRVLGDKVRHAVEVLPLVSVISIVIIVAAVVAASQAKIAESGLLIMAVVMLHNSFGYLLG
YFTGRLFGLPLPQRKSLALEVGMQNSGLGAALASAHFSPLAAVPSALFSVWHNISGALLSTYFRRMSEKQDSETLAQQAA
D

Sequences:

>Translated_321_residues
MRALAALSRFVGNTFAYWVLIFAVIAFLQPAWFLGLKGAIVPLLGLVMFGMGLTLKLDDFAAVARHPWRVALGVVAHFVI
MPGMAWLLCQIFHLPPEIAVGVILVGCCPSGTSSNVMTWLARGDLALSVAIAAVTTLLAPLLTPALIWLLASAWLPVSFM
ELFWSILQVVLLPIVLGVVAQRVLGDKVRHAVEVLPLVSVISIVIIVAAVVAASQAKIAESGLLIMAVVMLHNSFGYLLG
YFTGRLFGLPLPQRKSLALEVGMQNSGLGAALASAHFSPLAAVPSALFSVWHNISGALLSTYFRRMSEKQDSETLAQQAA
D
>Mature_321_residues
MRALAALSRFVGNTFAYWVLIFAVIAFLQPAWFLGLKGAIVPLLGLVMFGMGLTLKLDDFAAVARHPWRVALGVVAHFVI
MPGMAWLLCQIFHLPPEIAVGVILVGCCPSGTSSNVMTWLARGDLALSVAIAAVTTLLAPLLTPALIWLLASAWLPVSFM
ELFWSILQVVLLPIVLGVVAQRVLGDKVRHAVEVLPLVSVISIVIIVAAVVAASQAKIAESGLLIMAVVMLHNSFGYLLG
YFTGRLFGLPLPQRKSLALEVGMQNSGLGAALASAHFSPLAAVPSALFSVWHNISGALLSTYFRRMSEKQDSETLAQQAA
D

Specific function: Unknown

COG id: COG0385

COG function: function code R; Predicted Na+-dependent transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:bile acid symporter family [H]

Homologues:

Organism=Homo sapiens, GI4506973, Length=244, Percent_Identity=29.5081967213115, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI37537552, Length=290, Percent_Identity=26.551724137931, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4506971, Length=299, Percent_Identity=25.0836120401338, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI58219066, Length=236, Percent_Identity=28.8135593220339, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI24308414, Length=244, Percent_Identity=30.7377049180328, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004710
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 34276; Mature: 34276

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALAALSRFVGNTFAYWVLIFAVIAFLQPAWFLGLKGAIVPLLGLVMFGMGLTLKLDDF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHHHCCCCEEEEHHH
AAVARHPWRVALGVVAHFVIMPGMAWLLCQIFHLPPEIAVGVILVGCCPSGTSSNVMTWL
HHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHEECCCCCCCCHHHHHH
ARGDLALSVAIAAVTTLLAPLLTPALIWLLASAWLPVSFMELFWSILQVVLLPIVLGVVA
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
QRVLGDKVRHAVEVLPLVSVISIVIIVAAVVAASQAKIAESGLLIMAVVMLHNSFGYLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
YFTGRLFGLPLPQRKSLALEVGMQNSGLGAALASAHFSPLAAVPSALFSVWHNISGALLS
HHHHHHHCCCCCCCCCHHHEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TYFRRMSEKQDSETLAQQAAD
HHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure
MRALAALSRFVGNTFAYWVLIFAVIAFLQPAWFLGLKGAIVPLLGLVMFGMGLTLKLDDF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHHHCCCCEEEEHHH
AAVARHPWRVALGVVAHFVIMPGMAWLLCQIFHLPPEIAVGVILVGCCPSGTSSNVMTWL
HHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHEECCCCCCCCHHHHHH
ARGDLALSVAIAAVTTLLAPLLTPALIWLLASAWLPVSFMELFWSILQVVLLPIVLGVVA
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
QRVLGDKVRHAVEVLPLVSVISIVIIVAAVVAASQAKIAESGLLIMAVVMLHNSFGYLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
YFTGRLFGLPLPQRKSLALEVGMQNSGLGAALASAHFSPLAAVPSALFSVWHNISGALLS
HHHHHHHCCCCCCCCCHHHEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TYFRRMSEKQDSETLAQQAAD
HHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]