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The map label for this gene is ccmE1

Identifier: 77457808

GI number: 77457808

Start: 1769187

End: 1769642

Strand: Direct

Name: ccmE1

Synonym: Pfl01_1581

Alternate gene names: 77457808

Gene position: 1769187-1769642 (Clockwise)

Preceding gene: 77457807

Following gene: 77457809

Centisome position: 27.48

GC content: 61.62

Gene sequence:

>456_bases
GTGAATCCGCTGCGTAAAAAGCGTCTGATCATCATCCTGGCAATTCTGGTCGGGGTCGGCGCTGCCGTCGGCCTGGCCCT
GAGCGCCCTGCAGCAGAACATCAACCTGTTTTACACGCCGACCCAGATCGCCAACGGCGAAGCGCCGCAAGACACCCGCA
TCCGTGCCGGCGGCATGGTCGAGAAGGGCTCACTGCAACGCTCCACAGATTCGCTGGACGTCAAATTCGTGGTCACCGAT
TTCAACAAGTCCGTGACCATCACCTATCGCGGGATCCTGCCGGACCTGTTCCGCGAAGGGCAGGGCATCGTCGCGCTCGG
CAAGCTCAACGCCGATGGCGTGGTGGTCGCCGATGAAGTGCTGGCCAAGCACGACGAGAAATACATGCCGCCGGAAGTGA
CCAAAGCCCTGAAGGACAGCGGTCAATCCGCGCCAACCCCTGCGAAGGAGGGTTGA

Upstream 100 bases:

>100_bases
TCTGTCTGGCGGTACTGATCCTCAACGTGGCGGCGCCGATCGCGGCCCGCAAGCGTTATCTGCAACAAGAGGCGCGTCGT
CTGCGCCGGGAGAACGGCAA

Downstream 100 bases:

>100_bases
TCGATGACATCCAGCATTTTCATTCCTGAGTTGGGCCATCTGGCCATGATCCTGGCGCTGTGTTTCGCGCTGGTGCAGGC
GGTGGTGCCGTTGCTCGGTG

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E 1; Heme chaperone CcmE 1

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MNPLRKKRLIIILAILVGVGAAVGLALSALQQNINLFYTPTQIANGEAPQDTRIRAGGMVEKGSLQRSTDSLDVKFVVTD
FNKSVTITYRGILPDLFREGQGIVALGKLNADGVVVADEVLAKHDEKYMPPEVTKALKDSGQSAPTPAKEG

Sequences:

>Translated_151_residues
MNPLRKKRLIIILAILVGVGAAVGLALSALQQNINLFYTPTQIANGEAPQDTRIRAGGMVEKGSLQRSTDSLDVKFVVTD
FNKSVTITYRGILPDLFREGQGIVALGKLNADGVVVADEVLAKHDEKYMPPEVTKALKDSGQSAPTPAKEG
>Mature_151_residues
MNPLRKKRLIIILAILVGVGAAVGLALSALQQNINLFYTPTQIANGEAPQDTRIRAGGMVEKGSLQRSTDSLDVKFVVTD
FNKSVTITYRGILPDLFREGQGIVALGKLNADGVVVADEVLAKHDEKYMPPEVTKALKDSGQSAPTPAKEG

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=144, Percent_Identity=51.3888888888889, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME1_PSEPF (Q3KFY2)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_347313.1
- ProteinModelPortal:   Q3KFY2
- SMR:   Q3KFY2
- STRING:   Q3KFY2
- GeneID:   3716949
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_1581
- eggNOG:   COG2332
- HOGENOM:   HBG296631
- OMA:   HVEFAVH
- ProtClustDB:   PRK13254
- BioCyc:   PFLU205922:PFL_1581-MONOMER
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 16143; Mature: 16143

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: BINDING 124-124

Signals:

None

Transmembrane regions:

HASH(0xe9e263c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLRKKRLIIILAILVGVGAAVGLALSALQQNINLFYTPTQIANGEAPQDTRIRAGGMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEECCCCC
EKGSLQRSTDSLDVKFVVTDFNKSVTITYRGILPDLFREGQGIVALGKLNADGVVVADEV
CCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCHHHHHCCCCEEEEEEECCCCEEEHHHH
LAKHDEKYMPPEVTKALKDSGQSAPTPAKEG
HHHCCCCCCCHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure
MNPLRKKRLIIILAILVGVGAAVGLALSALQQNINLFYTPTQIANGEAPQDTRIRAGGMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEECCCCC
EKGSLQRSTDSLDVKFVVTDFNKSVTITYRGILPDLFREGQGIVALGKLNADGVVVADEV
CCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCHHHHHCCCCEEEEEEECCCCEEEHHHH
LAKHDEKYMPPEVTKALKDSGQSAPTPAKEG
HHHCCCCCCCHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA