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The map label for this gene is ptrB [H]

Identifier: 77457626

GI number: 77457626

Start: 1570199

End: 1572253

Strand: Reverse

Name: ptrB [H]

Synonym: Pfl01_1399

Alternate gene names: 77457626

Gene position: 1572253-1570199 (Counterclockwise)

Preceding gene: 77457630

Following gene: 77457625

Centisome position: 24.42

GC content: 62.87

Gene sequence:

>2055_bases
ATGCCCGTATCCGCCAACGTCATCAGCGCCCCGATTGCCCACAAGGCCGCCGGTCACGACCCGTACGCCTGGCTGCAGGA
ACGCGACACCGACGCGGTGCTCGACTACCTCAAGGCTGAAAACGACTATCAGCAGGCGCAGACCGCCGATCAGGCCGAAC
TGCGTGAAACCCTGTTCGAAGAGATCAAGGGCCGGATCCTCGAAACCGACCTGTCGCTGCCATCGCCATGGGGCCCGTAC
CTGTATTACACCCGCACCACAGCGGGTGACGAATACGCCCGCCACTACCGCTGCCCGCGTCCGGCCGACGACAGCCTGAC
CCTCGACGAAAGCCGCGAACAATTGCTGCTCGACCCGAACGCCCTGGCCAATGGCGGCTTTTTCTCCCTGGGCGCGTTCA
GCATCAGCCCGGATCACCAGCGTCTGGCCTACAGCGTCGATGCCTCGGGCGACGAGATTTACACGCTGTTCGTGAAGGAA
TTGTCCAGCGAGCGCGTCAGCGAACTGGAATTCCAGGACTGCGACGGCAGCATGACCTGGGCCAACGACAGCCTCACGCT
GTTCTTCGGCGTGCTCGACGACACCCACCGCCCGCACAAACTGTTCCGCTACCGCCTGGACGGCACCGCCGCCGAAGAGG
TGTTCCACGAGCCGGACGGGCGTTTCTTCCTGCATTGCTACCGCGCCAGCTCCGAGCAGCAATTGCTGTTGTCCCTGGGC
AGCAAGACCACCAGCGAAGTCTGGGCGCTGGATGCCAATCAGCCGCAGCAGCCATTCACTTGCCTGGCGCCACGGGTCGA
GGATCACGAGTACGACGTCGATCACGGCAAGCTCGATGGCGAATGGACCTGGTTCATCCGCACCAACCGCGACGGCATCA
ACTTCGCCCTGTATCAGGCGCCGGACACCGGTATTGCACCGAGCGAAGCCGACTGGCAGAACCTGATTCCGCACAGTGAT
TCGGTGATGCTCGATGGCGTGACCCTCAACGCCGAAGCCCTGACCCTGAGCCTGCGCGAGGGTGGTCTGCCAATCATCGA
AGTTCGACCACACGGTCTGGCGCCTTATCGCGTGCAACTACCGGACGCGGCCTACAGCCTCTACGTGCAAAACAGCCTGG
AATTCGAAAGTGACCGCATTCGCCTGCGCTATGAAGCGCTGAATCGTCCGGCTCAGGTTCGGCAACTGATCCTCGCCACC
GGCGAGCAGACTGTGCTCAAGGAAACCCCGGTGCTCGGCCCGTTCGACGCCGACGCCTACGTCAGCCAGCGCCTGTGGGC
GACCGCGCCGGACGGCACCCAGGTGCCGATCAGTCTGGTGATGAAACGGGAAATGGTCGGCAAAGCGGTGCCGCTGTACC
TGTACGGTTACGGCGCCTACGGCTCAAGCCTCGACCCGTGGTTCTCCCACGCCCGCCTGAGTCTGCTGGATCGCGGCATG
GCGTTCGCCATCGCCCATGTGCGCGGCGGCGGTGAACTGGGCGAAGCCTGGTACCGCGCCGGCAAGCAGGAGCACAAGCA
CAACACGTTCAGCGACTTCATTGCCTGCGCCGAATTCCTGATCCTCAACGGCATCACCACCGCGCCACAGCTGGCGATCA
GTGGCGGCAGCGCTGGTGGTTTGCTGATCGGTGCGGTGCTCAACCAGCGTCCGGATCTGTTCGGTGTGGCGATTGCCGAA
GTGCCGTTCGTCGACGTGCTCAATACCATGCTCGACCCGGACCTGCCGCTGACCGTCACTGAATACGACGAGTGGGGCAA
TCCCGAAGAGCCGGAGGTCTACGAGCGGATCAAGGCCTACGCGCCGTACGAAAACGTCACCGCGCAGGCCTATCCCGCAA
CGTTGGTGATCGCCGGCTACAACGACAGCCGCGTGCAGTATTGGGAAGCGGCCAAGTGGGTGGCGAAATTGCGCGCGACC
AAGACCGATGACAATCCGCTGCTGCTCAAGACTGAACTGGGCGCCGGCCACGGTGGCATGAGCGGGCGTTATCAGGGATT
ACGTGACGTAGCGCTCGAATATGCATTTGTTTTCAAGGTTCTGGGCATTGTCTGA

Upstream 100 bases:

>100_bases
TGGCAAGGCAGGCAAATAGGCGCTTATAGTAACGACTTTTCGCACGTCAGGCTTCCCCGCCGTCCGTGCGGCCCTTATTT
GTCATGTCCGAGAGCTTTCC

Downstream 100 bases:

>100_bases
GGAACTCCGCCGGTCAGTCAGGTCTTAATTCCGGGCACCGGGAGCCGATAAGCAGATCGGCCCCCGGTGGCGAGCCTGCC
ACCCGACACAACAAAAAGAT

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MPVSANVISAPIAHKAAGHDPYAWLQERDTDAVLDYLKAENDYQQAQTADQAELRETLFEEIKGRILETDLSLPSPWGPY
LYYTRTTAGDEYARHYRCPRPADDSLTLDESREQLLLDPNALANGGFFSLGAFSISPDHQRLAYSVDASGDEIYTLFVKE
LSSERVSELEFQDCDGSMTWANDSLTLFFGVLDDTHRPHKLFRYRLDGTAAEEVFHEPDGRFFLHCYRASSEQQLLLSLG
SKTTSEVWALDANQPQQPFTCLAPRVEDHEYDVDHGKLDGEWTWFIRTNRDGINFALYQAPDTGIAPSEADWQNLIPHSD
SVMLDGVTLNAEALTLSLREGGLPIIEVRPHGLAPYRVQLPDAAYSLYVQNSLEFESDRIRLRYEALNRPAQVRQLILAT
GEQTVLKETPVLGPFDADAYVSQRLWATAPDGTQVPISLVMKREMVGKAVPLYLYGYGAYGSSLDPWFSHARLSLLDRGM
AFAIAHVRGGGELGEAWYRAGKQEHKHNTFSDFIACAEFLILNGITTAPQLAISGGSAGGLLIGAVLNQRPDLFGVAIAE
VPFVDVLNTMLDPDLPLTVTEYDEWGNPEEPEVYERIKAYAPYENVTAQAYPATLVIAGYNDSRVQYWEAAKWVAKLRAT
KTDDNPLLLKTELGAGHGGMSGRYQGLRDVALEYAFVFKVLGIV

Sequences:

>Translated_684_residues
MPVSANVISAPIAHKAAGHDPYAWLQERDTDAVLDYLKAENDYQQAQTADQAELRETLFEEIKGRILETDLSLPSPWGPY
LYYTRTTAGDEYARHYRCPRPADDSLTLDESREQLLLDPNALANGGFFSLGAFSISPDHQRLAYSVDASGDEIYTLFVKE
LSSERVSELEFQDCDGSMTWANDSLTLFFGVLDDTHRPHKLFRYRLDGTAAEEVFHEPDGRFFLHCYRASSEQQLLLSLG
SKTTSEVWALDANQPQQPFTCLAPRVEDHEYDVDHGKLDGEWTWFIRTNRDGINFALYQAPDTGIAPSEADWQNLIPHSD
SVMLDGVTLNAEALTLSLREGGLPIIEVRPHGLAPYRVQLPDAAYSLYVQNSLEFESDRIRLRYEALNRPAQVRQLILAT
GEQTVLKETPVLGPFDADAYVSQRLWATAPDGTQVPISLVMKREMVGKAVPLYLYGYGAYGSSLDPWFSHARLSLLDRGM
AFAIAHVRGGGELGEAWYRAGKQEHKHNTFSDFIACAEFLILNGITTAPQLAISGGSAGGLLIGAVLNQRPDLFGVAIAE
VPFVDVLNTMLDPDLPLTVTEYDEWGNPEEPEVYERIKAYAPYENVTAQAYPATLVIAGYNDSRVQYWEAAKWVAKLRAT
KTDDNPLLLKTELGAGHGGMSGRYQGLRDVALEYAFVFKVLGIV
>Mature_683_residues
PVSANVISAPIAHKAAGHDPYAWLQERDTDAVLDYLKAENDYQQAQTADQAELRETLFEEIKGRILETDLSLPSPWGPYL
YYTRTTAGDEYARHYRCPRPADDSLTLDESREQLLLDPNALANGGFFSLGAFSISPDHQRLAYSVDASGDEIYTLFVKEL
SSERVSELEFQDCDGSMTWANDSLTLFFGVLDDTHRPHKLFRYRLDGTAAEEVFHEPDGRFFLHCYRASSEQQLLLSLGS
KTTSEVWALDANQPQQPFTCLAPRVEDHEYDVDHGKLDGEWTWFIRTNRDGINFALYQAPDTGIAPSEADWQNLIPHSDS
VMLDGVTLNAEALTLSLREGGLPIIEVRPHGLAPYRVQLPDAAYSLYVQNSLEFESDRIRLRYEALNRPAQVRQLILATG
EQTVLKETPVLGPFDADAYVSQRLWATAPDGTQVPISLVMKREMVGKAVPLYLYGYGAYGSSLDPWFSHARLSLLDRGMA
FAIAHVRGGGELGEAWYRAGKQEHKHNTFSDFIACAEFLILNGITTAPQLAISGGSAGGLLIGAVLNQRPDLFGVAIAEV
PFVDVLNTMLDPDLPLTVTEYDEWGNPEEPEVYERIKAYAPYENVTAQAYPATLVIAGYNDSRVQYWEAAKWVAKLRATK
TDDNPLLLKTELGAGHGGMSGRYQGLRDVALEYAFVFKVLGIV

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=706, Percent_Identity=25.9206798866856, Blast_Score=205, Evalue=9e-53,
Organism=Homo sapiens, GI284172420, Length=521, Percent_Identity=30.3262955854127, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI284172413, Length=521, Percent_Identity=30.3262955854127, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI70778815, Length=521, Percent_Identity=30.3262955854127, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI284172438, Length=521, Percent_Identity=30.3262955854127, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI284172431, Length=521, Percent_Identity=30.3262955854127, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI108860686, Length=217, Percent_Identity=40.0921658986175, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI108860692, Length=210, Percent_Identity=40, Blast_Score=138, Evalue=2e-32,
Organism=Escherichia coli, GI1788150, Length=687, Percent_Identity=39.5924308588064, Blast_Score=459, Evalue=1e-130,
Organism=Drosophila melanogaster, GI24583414, Length=711, Percent_Identity=26.1603375527426, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI221510989, Length=688, Percent_Identity=25.8720930232558, Blast_Score=193, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 76167; Mature: 76036

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSANVISAPIAHKAAGHDPYAWLQERDTDAVLDYLKAENDYQQAQTADQAELRETLFE
CCCCCCHHCCCHHHHCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHH
EIKGRILETDLSLPSPWGPYLYYTRTTAGDEYARHYRCPRPADDSLTLDESREQLLLDPN
HHCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCEECCCCCCEEEECCC
ALANGGFFSLGAFSISPDHQRLAYSVDASGDEIYTLFVKELSSERVSELEFQDCDGSMTW
CCCCCCCEEEEEEEECCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCEEE
ANDSLTLFFGVLDDTHRPHKLFRYRLDGTAAEEVFHEPDGRFFLHCYRASSEQQLLLSLG
ECCCEEEEEEECCCCCCCCHHEEEECCCCHHHHHHHCCCCCEEEEEEECCCHHHHHHHHC
SKTTSEVWALDANQPQQPFTCLAPRVEDHEYDVDHGKLDGEWTWFIRTNRDGINFALYQA
CCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEC
PDTGIAPSEADWQNLIPHSDSVMLDGVTLNAEALTLSLREGGLPIIEVRPHGLAPYRVQL
CCCCCCCCCCCHHHCCCCCCCEEEEEEEECCEEEEEEEECCCCCEEEECCCCCCCEEEEC
PDAAYSLYVQNSLEFESDRIRLRYEALNRPAQVRQLILATGEQTVLKETPVLGPFDADAY
CCCEEEEEEECCCCCCCCCEEEEEHHHCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHH
VSQRLWATAPDGTQVPISLVMKREMVGKAVPLYLYGYGAYGSSLDPWFSHARLSLLDRGM
HHHHHEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCC
AFAIAHVRGGGELGEAWYRAGKQEHKHNTFSDFIACAEFLILNGITTAPQLAISGGSAGG
EEEEEEECCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCC
LLIGAVLNQRPDLFGVAIAEVPFVDVLNTMLDPDLPLTVTEYDEWGNPEEPEVYERIKAY
HHHHHHHCCCCCEEEEEHHHCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHC
APYENVTAQAYPATLVIAGYNDSRVQYWEAAKWVAKLRATKTDDNPLLLKTELGAGHGGM
CCCCCCCCEECCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCC
SGRYQGLRDVALEYAFVFKVLGIV
CCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVSANVISAPIAHKAAGHDPYAWLQERDTDAVLDYLKAENDYQQAQTADQAELRETLFE
CCCCCHHCCCHHHHCCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHH
EIKGRILETDLSLPSPWGPYLYYTRTTAGDEYARHYRCPRPADDSLTLDESREQLLLDPN
HHCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCEECCCCCCEEEECCC
ALANGGFFSLGAFSISPDHQRLAYSVDASGDEIYTLFVKELSSERVSELEFQDCDGSMTW
CCCCCCCEEEEEEEECCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCEEE
ANDSLTLFFGVLDDTHRPHKLFRYRLDGTAAEEVFHEPDGRFFLHCYRASSEQQLLLSLG
ECCCEEEEEEECCCCCCCCHHEEEECCCCHHHHHHHCCCCCEEEEEEECCCHHHHHHHHC
SKTTSEVWALDANQPQQPFTCLAPRVEDHEYDVDHGKLDGEWTWFIRTNRDGINFALYQA
CCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEC
PDTGIAPSEADWQNLIPHSDSVMLDGVTLNAEALTLSLREGGLPIIEVRPHGLAPYRVQL
CCCCCCCCCCCHHHCCCCCCCEEEEEEEECCEEEEEEEECCCCCEEEECCCCCCCEEEEC
PDAAYSLYVQNSLEFESDRIRLRYEALNRPAQVRQLILATGEQTVLKETPVLGPFDADAY
CCCEEEEEEECCCCCCCCCEEEEEHHHCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHH
VSQRLWATAPDGTQVPISLVMKREMVGKAVPLYLYGYGAYGSSLDPWFSHARLSLLDRGM
HHHHHEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCC
AFAIAHVRGGGELGEAWYRAGKQEHKHNTFSDFIACAEFLILNGITTAPQLAISGGSAGG
EEEEEEECCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCC
LLIGAVLNQRPDLFGVAIAEVPFVDVLNTMLDPDLPLTVTEYDEWGNPEEPEVYERIKAY
HHHHHHHCCCCCEEEEEHHHCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHC
APYENVTAQAYPATLVIAGYNDSRVQYWEAAKWVAKLRATKTDDNPLLLKTELGAGHGGM
CCCCCCCCEECCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCC
SGRYQGLRDVALEYAFVFKVLGIV
CCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]