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The map label for this gene is trxB [H]

Identifier: 77457114

GI number: 77457114

Start: 1034817

End: 1035779

Strand: Direct

Name: trxB [H]

Synonym: Pfl01_0887

Alternate gene names: 77457114

Gene position: 1034817-1035779 (Clockwise)

Preceding gene: 77457111

Following gene: 77457121

Centisome position: 16.07

GC content: 61.79

Gene sequence:

>963_bases
ATGTCTGAATTCCGTCATTCGCGAGTGATCATCCTCGGTTCCGGCCCTGCCGGTTACAGCGCTGCCGTCTACGCTGCCCG
CGCCAACCTCAAGCCGCTGCTGATCACCGGCATGCAGGCCGGCGGTCAACTGACCACCACCACCGAAGTCGACAACTGGC
CGGGCGACGTCCATGGTCTGACCGGCCCGGTGCTGATGGAGCGCATGCGCGAGCACGCCGAGCGTTTTGAAACCGAGATC
GTGTTCGATCACATCAATGCTGTGGACTTCGCTTCCAAGCCATACAGCCTGACCGGCGACAGCGGCACCTACACCTGCGA
CGCGCTGATCATCGCCACTGGCGCAAGCGCTCGTTACCTGGGCCTGCCTTCGGAAGAAGCGTTCATGGGCAAAGGCGTTT
CCGCCTGTGCGACCTGCGACGGTTTCTTCTATCGCAACAAGCCGGTGGCCGTGGTCGGTGGCGGCAACACCGCTGTCGAG
GAAGCCCTGTACCTGGCCAATATCGCCAGCAAGGTCACCCTGATCCACCGTCGCGAAACCTTCCGCGCCGAGAAGATCCT
GATCGACAAGCTCAACGCCCGTGTGGCCGAAGGCAAGATCGAGCTGAAACTGAACGCGACCCTGGACGAAGTGCTGGGCG
ACAACATGGGCGTGACCGGTGCGCGTCTGAAGAACAACGACGGCAGCTTCGACGAAATCAAGGTCGACGGCGTGTTCATC
GCGATCGGCCACACTCCGAACACCTCGCTGTTCGAAGGTCAGCTGGAATTGAAAGACGGCTACTTGGTCGTTCAGGGTGG
CCGTGAAGGTAACGCCACTGCGACCAGCGTCGAAGGCATCTTCGCTGCCGGTGACGTGGCCGACCACGTTTACCGTCAGG
CCATCACCTCGGCCGGCGCCGGCTGCATGGCGGCACTGGACACCGAGCGTTACCTGGACGGTTTGCAGAACGCTTCGTTC
TAA

Upstream 100 bases:

>100_bases
GAGCTCACGCCTTCCCCAAGGTTATCCACAGTCCTTTTTTATTCCCGCCGGCAGTCCGGCGTCCGGCCAGGTGTCTTGGC
CGGTCAACAGGAGCAGGTTC

Downstream 100 bases:

>100_bases
GATCGCGGAAACGAAAAAACCGGCCACGTGGCCGGTTTTTTCATGCCTGCGATTCGCTGGGGAATCAGCGGCGGGTCAGC
GGTTGCGCTTCGAATTTCAC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSEFRHSRVIILGSGPAGYSAAVYAARANLKPLLITGMQAGGQLTTTTEVDNWPGDVHGLTGPVLMERMREHAERFETEI
VFDHINAVDFASKPYSLTGDSGTYTCDALIIATGASARYLGLPSEEAFMGKGVSACATCDGFFYRNKPVAVVGGGNTAVE
EALYLANIASKVTLIHRRETFRAEKILIDKLNARVAEGKIELKLNATLDEVLGDNMGVTGARLKNNDGSFDEIKVDGVFI
AIGHTPNTSLFEGQLELKDGYLVVQGGREGNATATSVEGIFAAGDVADHVYRQAITSAGAGCMAALDTERYLDGLQNASF

Sequences:

>Translated_320_residues
MSEFRHSRVIILGSGPAGYSAAVYAARANLKPLLITGMQAGGQLTTTTEVDNWPGDVHGLTGPVLMERMREHAERFETEI
VFDHINAVDFASKPYSLTGDSGTYTCDALIIATGASARYLGLPSEEAFMGKGVSACATCDGFFYRNKPVAVVGGGNTAVE
EALYLANIASKVTLIHRRETFRAEKILIDKLNARVAEGKIELKLNATLDEVLGDNMGVTGARLKNNDGSFDEIKVDGVFI
AIGHTPNTSLFEGQLELKDGYLVVQGGREGNATATSVEGIFAAGDVADHVYRQAITSAGAGCMAALDTERYLDGLQNASF
>Mature_319_residues
SEFRHSRVIILGSGPAGYSAAVYAARANLKPLLITGMQAGGQLTTTTEVDNWPGDVHGLTGPVLMERMREHAERFETEIV
FDHINAVDFASKPYSLTGDSGTYTCDALIIATGASARYLGLPSEEAFMGKGVSACATCDGFFYRNKPVAVVGGGNTAVEE
ALYLANIASKVTLIHRRETFRAEKILIDKLNARVAEGKIELKLNATLDEVLGDNMGVTGARLKNNDGSFDEIKVDGVFIA
IGHTPNTSLFEGQLELKDGYLVVQGGREGNATATSVEGIFAAGDVADHVYRQAITSAGAGCMAALDTERYLDGLQNASF

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=71.0280373831776, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI87081763, Length=316, Percent_Identity=33.2278481012658, Blast_Score=139, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=47.2222222222222, Blast_Score=280, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6321898, Length=325, Percent_Identity=45.2307692307692, Blast_Score=268, Evalue=6e-73,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34050; Mature: 33919

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFRHSRVIILGSGPAGYSAAVYAARANLKPLLITGMQAGGQLTTTTEVDNWPGDVHGL
CCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPVLMERMREHAERFETEIVFDHINAVDFASKPYSLTGDSGTYTCDALIIATGASARYL
CHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEECCCCCEEEEEEEEEECCCEEEE
GLPSEEAFMGKGVSACATCDGFFYRNKPVAVVGGGNTAVEEALYLANIASKVTLIHRRET
CCCCCHHHHCCCCCHHEECCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHEEEEEHHHH
FRAEKILIDKLNARVAEGKIELKLNATLDEVLGDNMGVTGARLKNNDGSFDEIKVDGVFI
HHHHHHHHHHHCCEEECCEEEEEECCCHHHHCCCCCCCCCEEEECCCCCCCEEEEEEEEE
AIGHTPNTSLFEGQLELKDGYLVVQGGREGNATATSVEGIFAAGDVADHVYRQAITSAGA
EEECCCCCCEEECEEEEECCEEEEECCCCCCCEEEEECEEEECCHHHHHHHHHHHHHCCC
GCMAALDTERYLDGLQNASF
CCEEEECHHHHHHHHHCCCC
>Mature Secondary Structure 
SEFRHSRVIILGSGPAGYSAAVYAARANLKPLLITGMQAGGQLTTTTEVDNWPGDVHGL
CCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPVLMERMREHAERFETEIVFDHINAVDFASKPYSLTGDSGTYTCDALIIATGASARYL
CHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEECCCCCEEEEEEEEEECCCEEEE
GLPSEEAFMGKGVSACATCDGFFYRNKPVAVVGGGNTAVEEALYLANIASKVTLIHRRET
CCCCCHHHHCCCCCHHEECCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHEEEEEHHHH
FRAEKILIDKLNARVAEGKIELKLNATLDEVLGDNMGVTGARLKNNDGSFDEIKVDGVFI
HHHHHHHHHHHCCEEECCEEEEEECCCHHHHCCCCCCCCCEEEECCCCCCCEEEEEEEEE
AIGHTPNTSLFEGQLELKDGYLVVQGGREGNATATSVEGIFAAGDVADHVYRQAITSAGA
EEECCCCCCEEECEEEEECCEEEEECCCCCCCEEEEECEEEECCHHHHHHHHHHHHHCCC
GCMAALDTERYLDGLQNASF
CCEEEECHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]