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The map label for this gene is mlrA [H]

Identifier: 77457121

GI number: 77457121

Start: 1039043

End: 1040002

Strand: Direct

Name: mlrA [H]

Synonym: Pfl01_0894

Alternate gene names: 77457121

Gene position: 1039043-1040002 (Clockwise)

Preceding gene: 77457114

Following gene: 77457124

Centisome position: 16.14

GC content: 58.96

Gene sequence:

>960_bases
ATGCCTGTGATCACAGACGTTCGCCCTGCTTCGCAGGAATCTGTTGCGCTGGAGCGCGAGGATCTTTTCCCTATACGTGA
AGTGGCGCGCCTGACCGGGGTGAACCCGGTGACATTGCGCGCATGGGAGCGGCGATACGGATTGATCCAGCCAACGCGCA
CCGAGAGTGGGCATCGCCTGTATTCGATGACCGATATCGAGCGTGTTCGCAGCATCGTCGACTGGATCGACCGGGGTGTT
GCCGTGAGCAAGGTGGGCAAGATCCTGGCCAAGACCGAGCCGATGAAGGTGCTGGCTCATCTGATTCCCGATGACCTGGT
GCACGCGGACTATATCCAGTGGCAGGAGCAGGTTAAGCAGGCGGTCAGCACTTTCGACGATCAGTTGCTTGATCGGGTCT
ACGGTCAGATTTTCTCTTCCTATGCTTTGCCCGTGGTGTTTCAGGACATCCTGATGCCGCTGTGGCTGCAAATGCTGCAG
CGTCAGGATGCATTCGGGCAAACCAGTGAGTGGTTGTTCTTCGATGGTTTTCTGAGAGCCAAGGTGCTGCAGCGCATTGT
CGTGCTGCGTGGCTCGCAACCGCGCAAGGTAATTGTCAGCGCGCTGGCCGGTCAATGTCGCGAGCTCGAATTGCTGGTGG
CGGCGCTGTTCCTCAGTGGCAATGACGCGGGCGTTCGTGTGCTCACGACCGGTCAGCCGTTCGATGAGCTGACGCTGGTG
TGCGAAAAGATCAAACCTCAAGCCCTCGTGCTTTTTTCCAATCACGCACCGACTGCCGAGCTTCCAAGGCGGCTGAACCG
GTTGGCGCTGAGTCTGGATTGTCAGTTGCTGCTGGCGGGCGATGCGGCCGATCTGGCCCAGGACAGCCTGGCGGGATCAT
CGGTCGGCTGTCTGGGCAATGAAGGTTCGACAATGCGCCAGCGAATGAATCAGTTTCTGGCGGGGACGCTGGATACCTGA

Upstream 100 bases:

>100_bases
GACGAACCCGAGACTTTCGTTCCATTTGATCGCTTGAACCTTCATGGGGCATCAGGAGTAGAATGGATCCAACTTTGCCA
ACAAGGACGTGTCCGCACCA

Downstream 100 bases:

>100_bases
GTATCAGGTGTGCAGGGCAGGGTGGGTCAGACGATGCTGTTGCAGAATGAACTGGCGCAGACGCTCGGTTTCGTCGGCAT
CGCTCTGGCTCAGCTCGTAA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: MerR-like regulator A [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MPVITDVRPASQESVALEREDLFPIREVARLTGVNPVTLRAWERRYGLIQPTRTESGHRLYSMTDIERVRSIVDWIDRGV
AVSKVGKILAKTEPMKVLAHLIPDDLVHADYIQWQEQVKQAVSTFDDQLLDRVYGQIFSSYALPVVFQDILMPLWLQMLQ
RQDAFGQTSEWLFFDGFLRAKVLQRIVVLRGSQPRKVIVSALAGQCRELELLVAALFLSGNDAGVRVLTTGQPFDELTLV
CEKIKPQALVLFSNHAPTAELPRRLNRLALSLDCQLLLAGDAADLAQDSLAGSSVGCLGNEGSTMRQRMNQFLAGTLDT

Sequences:

>Translated_319_residues
MPVITDVRPASQESVALEREDLFPIREVARLTGVNPVTLRAWERRYGLIQPTRTESGHRLYSMTDIERVRSIVDWIDRGV
AVSKVGKILAKTEPMKVLAHLIPDDLVHADYIQWQEQVKQAVSTFDDQLLDRVYGQIFSSYALPVVFQDILMPLWLQMLQ
RQDAFGQTSEWLFFDGFLRAKVLQRIVVLRGSQPRKVIVSALAGQCRELELLVAALFLSGNDAGVRVLTTGQPFDELTLV
CEKIKPQALVLFSNHAPTAELPRRLNRLALSLDCQLLLAGDAADLAQDSLAGSSVGCLGNEGSTMRQRMNQFLAGTLDT
>Mature_318_residues
PVITDVRPASQESVALEREDLFPIREVARLTGVNPVTLRAWERRYGLIQPTRTESGHRLYSMTDIERVRSIVDWIDRGVA
VSKVGKILAKTEPMKVLAHLIPDDLVHADYIQWQEQVKQAVSTFDDQLLDRVYGQIFSSYALPVVFQDILMPLWLQMLQR
QDAFGQTSEWLFFDGFLRAKVLQRIVVLRGSQPRKVIVSALAGQCRELELLVAALFLSGNDAGVRVLTTGQPFDELTLVC
EKIKPQALVLFSNHAPTAELPRRLNRLALSLDCQLLLAGDAADLAQDSLAGSSVGCLGNEGSTMRQRMNQFLAGTLDT

Specific function: Transcriptional activator of the csg genes required for production of the curli (AgF) [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788448, Length=76, Percent_Identity=57.8947368421053, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787409, Length=70, Percent_Identity=52.8571428571429, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 35642; Mature: 35510

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVITDVRPASQESVALEREDLFPIREVARLTGVNPVTLRAWERRYGLIQPTRTESGHRL
CCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEE
YSMTDIERVRSIVDWIDRGVAVSKVGKILAKTEPMKVLAHLIPDDLVHADYIQWQEQVKQ
EEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
AVSTFDDQLLDRVYGQIFSSYALPVVFQDILMPLWLQMLQRQDAFGQTSEWLFFDGFLRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
KVLQRIVVLRGSQPRKVIVSALAGQCRELELLVAALFLSGNDAGVRVLTTGQPFDELTLV
HHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
CEKIKPQALVLFSNHAPTAELPRRLNRLALSLDCQLLLAGDAADLAQDSLAGSSVGCLGN
HHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHCCCCCCCCCCC
EGSTMRQRMNQFLAGTLDT
CCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PVITDVRPASQESVALEREDLFPIREVARLTGVNPVTLRAWERRYGLIQPTRTESGHRL
CCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEE
YSMTDIERVRSIVDWIDRGVAVSKVGKILAKTEPMKVLAHLIPDDLVHADYIQWQEQVKQ
EEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
AVSTFDDQLLDRVYGQIFSSYALPVVFQDILMPLWLQMLQRQDAFGQTSEWLFFDGFLRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
KVLQRIVVLRGSQPRKVIVSALAGQCRELELLVAALFLSGNDAGVRVLTTGQPFDELTLV
HHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
CEKIKPQALVLFSNHAPTAELPRRLNRLALSLDCQLLLAGDAADLAQDSLAGSSVGCLGN
HHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHCCCCCCCCCCC
EGSTMRQRMNQFLAGTLDT
CCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11489123; 9278503 [H]