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The map label for this gene is tldD [H]

Identifier: 77457072

GI number: 77457072

Start: 996019

End: 997461

Strand: Direct

Name: tldD [H]

Synonym: Pfl01_0845

Alternate gene names: 77457072

Gene position: 996019-997461 (Clockwise)

Preceding gene: 77457071

Following gene: 77457074

Centisome position: 15.47

GC content: 63.2

Gene sequence:

>1443_bases
ATGAGCGAGTTGTTGTCCTCAGTCAGTGATCACCTGTTGGCGCCCGGCGGCGTGACGATCGAGAGTCTGCAAGGCGTGCT
CGGTGATCTGGCGGGTCCAGGCATCGATGCGGCCGACCTGTATTTCCAGGGGCAGATTTCCGAGTCCTGGTCGCTGGAAG
ACGGCATCGTCAAGGAAGGCAGTTTCAACCTCGACCAGGGCGTCGGCGTGCGTGCGCAGTCCGGCGAAAAAACCGGTTTC
GCCTACAGCAACGCGATCACCCTCGAAGCCCTCGGCGCAGCGGCCCGTGCGGCCCGTTCGATTTCCCGCGCCGGGCAGAA
CGGCACAGTGCAGGCTTTCAGCAGCCAGGACGTCGCCCAGTTGTATGCGCCGGACAACCCGCTGGAAGTCCTGAGCCGCG
CTGAAAAAGTCGAACTGCTCAAACGCATCGACGTGGCGACCCGCGCCCTCGACCCGCGTATCCAGCAGGTCAGCGTAAGC
ATGGCCGGGGTCTGGGAGCGAATTCTGGTGGCCTCGACTGACGGTGGCCTGGCTGCCGATGTGCGTCCGCTGGTGCGTTT
CAACGTCAGTGTGATCGTCGAACAGAACGGCCGTCGCGAACGCGGTGGTCATGGCGGCGGCGGGCGTACCGACTACCGTT
ATTTCCTCGCCGAAGACCGAGCCATGGGCTATGCCCGTGAAGCGTTGCGTCAGGCGCTGGTGAATCTGGAGGCGATTCCG
GCACCGGCCGGCACCTTGCCGGTGGTTCTGGGCTCGGGCTGGTCCGGCGTGTTGCTGCATGAAGCGGTCGGTCACGGTCT
GGAAGGCGATTTCAACCGCAAGGGCAGCTCTGCCTACAGCGGTCGCATGGGCGAAATGGTTGCTTCGAAACTCTGCACCA
TAGTCGATGACGGCACCCTGAGCGGTCGTCGCGGTTCCCTTAGCGTCGACGACGAAGGCACTCCGACCGAGTGCACCACG
CTGATCGAAAACGGTGTGCTCAAGGGCTACATGCAGGACAAGCTGAATGCGCGGCTGATGGGCGTGGCCCGCACCGGCAA
CGGTCGTCGCGAATCCTACGCGCACCTGCCGATGCCGCGGATGACCAATACCTACATGCTCGGCGGCCAGAGCGATCCGG
CGGAAATCATCGCGTCGGTGAAGAAGGGTATCTACTGCGCCAACCTCGGTGGCGGTCAGGTCGATATCACCAGCGGCAAG
TTCGTGTTTTCCACCAGTGAGGCTTATCTGATCGAGGACGGCAAGATCACCGCGCCAGTCAAAGGCGCAACGTTGATCGG
CAACGGTCCGGAAGCGATGAGCCGAGTGTCGATGGTCGGTAACGATCTGGCGCTGGACAGCGGTGTGGGCACATGCGGCA
AGGACGGGCAGTCGGTACCGGTGGGTGTCGGTCAGCCGACGCTGAAAATCGATGCGATCACCGTGGGTGGCACGGGCGCG
TAA

Upstream 100 bases:

>100_bases
CGTCCATCCGGGCGCGAATGCCGGTGACGGGTCATCGGCGGTTTTTTTCGCAGGGCGCACAGCGACCTGCTTCAGAACAC
GAATTTAAGGCGTAAAACCT

Downstream 100 bases:

>100_bases
GAAGGGATGGAGCTTCGGGTGGCGCGCGGTGCGGCCACCCGGTGACGAATATCAACGCAGACCGCGTTGAGTCTCGTCCA
GCTCACGGATGTACTTGAAG

Product: microcin-processing peptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MSELLSSVSDHLLAPGGVTIESLQGVLGDLAGPGIDAADLYFQGQISESWSLEDGIVKEGSFNLDQGVGVRAQSGEKTGF
AYSNAITLEALGAAARAARSISRAGQNGTVQAFSSQDVAQLYAPDNPLEVLSRAEKVELLKRIDVATRALDPRIQQVSVS
MAGVWERILVASTDGGLAADVRPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLAEDRAMGYAREALRQALVNLEAIP
APAGTLPVVLGSGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRMGEMVASKLCTIVDDGTLSGRRGSLSVDDEGTPTECTT
LIENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPRMTNTYMLGGQSDPAEIIASVKKGIYCANLGGGQVDITSGK
FVFSTSEAYLIEDGKITAPVKGATLIGNGPEAMSRVSMVGNDLALDSGVGTCGKDGQSVPVGVGQPTLKIDAITVGGTGA

Sequences:

>Translated_480_residues
MSELLSSVSDHLLAPGGVTIESLQGVLGDLAGPGIDAADLYFQGQISESWSLEDGIVKEGSFNLDQGVGVRAQSGEKTGF
AYSNAITLEALGAAARAARSISRAGQNGTVQAFSSQDVAQLYAPDNPLEVLSRAEKVELLKRIDVATRALDPRIQQVSVS
MAGVWERILVASTDGGLAADVRPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLAEDRAMGYAREALRQALVNLEAIP
APAGTLPVVLGSGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRMGEMVASKLCTIVDDGTLSGRRGSLSVDDEGTPTECTT
LIENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPRMTNTYMLGGQSDPAEIIASVKKGIYCANLGGGQVDITSGK
FVFSTSEAYLIEDGKITAPVKGATLIGNGPEAMSRVSMVGNDLALDSGVGTCGKDGQSVPVGVGQPTLKIDAITVGGTGA
>Mature_479_residues
SELLSSVSDHLLAPGGVTIESLQGVLGDLAGPGIDAADLYFQGQISESWSLEDGIVKEGSFNLDQGVGVRAQSGEKTGFA
YSNAITLEALGAAARAARSISRAGQNGTVQAFSSQDVAQLYAPDNPLEVLSRAEKVELLKRIDVATRALDPRIQQVSVSM
AGVWERILVASTDGGLAADVRPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLAEDRAMGYAREALRQALVNLEAIPA
PAGTLPVVLGSGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRMGEMVASKLCTIVDDGTLSGRRGSLSVDDEGTPTECTTL
IENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPRMTNTYMLGGQSDPAEIIASVKKGIYCANLGGGQVDITSGKF
VFSTSEAYLIEDGKITAPVKGATLIGNGPEAMSRVSMVGNDLALDSGVGTCGKDGQSVPVGVGQPTLKIDAITVGGTGA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=478, Percent_Identity=65.2719665271967, Blast_Score=615, Evalue=1e-177,
Organism=Escherichia coli, GI1790682, Length=438, Percent_Identity=23.7442922374429, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50051; Mature: 49920

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELLSSVSDHLLAPGGVTIESLQGVLGDLAGPGIDAADLYFQGQISESWSLEDGIVKEG
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEECCCCCCCCCCCCCCCC
SFNLDQGVGVRAQSGEKTGFAYSNAITLEALGAAARAARSISRAGQNGTVQAFSSQDVAQ
CCCCCCCCCCEECCCCCCCEEECCEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHH
LYAPDNPLEVLSRAEKVELLKRIDVATRALDPRIQQVSVSMAGVWERILVASTDGGLAAD
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEEECCCCCCCC
VRPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLAEDRAMGYAREALRQALVNLEAIP
CHHHHEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
APAGTLPVVLGSGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRMGEMVASKLCTIVDDGTL
CCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCC
SGRRGSLSVDDEGTPTECTTLIENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEECCCCCC
MTNTYMLGGQSDPAEIIASVKKGIYCANLGGGQVDITSGKFVFSTSEAYLIEDGKITAPV
CCCEEEECCCCCHHHHHHHHHCCEEEEECCCCEEEEECCEEEEECCCEEEEECCEEECCC
KGATLIGNGPEAMSRVSMVGNDLALDSGVGTCGKDGQSVPVGVGQPTLKIDAITVGGTGA
CCCEEECCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCC
>Mature Secondary Structure 
SELLSSVSDHLLAPGGVTIESLQGVLGDLAGPGIDAADLYFQGQISESWSLEDGIVKEG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEECCCCCCCCCCCCCCCC
SFNLDQGVGVRAQSGEKTGFAYSNAITLEALGAAARAARSISRAGQNGTVQAFSSQDVAQ
CCCCCCCCCCEECCCCCCCEEECCEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHH
LYAPDNPLEVLSRAEKVELLKRIDVATRALDPRIQQVSVSMAGVWERILVASTDGGLAAD
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEEECCCCCCCC
VRPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLAEDRAMGYAREALRQALVNLEAIP
CHHHHEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
APAGTLPVVLGSGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRMGEMVASKLCTIVDDGTL
CCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCC
SGRRGSLSVDDEGTPTECTTLIENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEECCCCCC
MTNTYMLGGQSDPAEIIASVKKGIYCANLGGGQVDITSGKFVFSTSEAYLIEDGKITAPV
CCCEEEECCCCCHHHHHHHHHCCEEEEECCCCEEEEECCEEEEECCCEEEEECCEEECCC
KGATLIGNGPEAMSRVSMVGNDLALDSGVGTCGKDGQSVPVGVGQPTLKIDAITVGGTGA
CCCEEECCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]