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The map label for this gene is rio2 [H]

Identifier: 77456886

GI number: 77456886

Start: 772874

End: 773770

Strand: Direct

Name: rio2 [H]

Synonym: Pfl01_0658

Alternate gene names: 77456886

Gene position: 772874-773770 (Clockwise)

Preceding gene: 77456884

Following gene: 77456887

Centisome position: 12.0

GC content: 62.76

Gene sequence:

>897_bases
ATGAAGACTCCAAAACGCATTGAACCCCTGATCGAGGACGGTCTGGTCGACGAAGTGCTGCGTCCACTCATGAGTGGCAA
AGAAGCAGCTGTTTATGTGGTGCGCTGCGGCAATCAGTTACGTTGCGCAAAGGTCTACAAGGAGGCGAACAAACGCAGTT
TCCGCCAGGCGGCCGAGTATCAGGAAGGCCGCAAGGTTCGCAACAGCCGACAGGCCCGGGCGATGGCCAAGGGCTCCAAG
TTCGGGCGCAAGGAAGCCGAAGACGCCTGGCAGAATGCCGAAGTCGCGGCGCTGTTCCGCCTGGCCAATGCCGGAGTGCG
TGTGCCCAAGCCGTACGACTTCCTCGAGGGCGTGCTGCTGATGGAGCTGGTGGCCGACGAATACGGCGATGCCGCGCCGC
GTCTGAACGACGTGGTGCTGGAGCCGGATCAGGCCCGCGAATATCACGCGTTCCTGATTTCGCAGATCGTGCTGATGTTG
TGTACCGGTCTGGTGCACGGTGACCTCTCCGAGTTCAACGTGCTGCTGACGCCAACCGGCCCGGTCATCATCGACCTGCC
GCAAGCGGTGGACGCCGCCGGCAACAACCACGCGTTCAGCATGCTGGAACGTGACGTCGGCAACATGGCTTCGTACTTCG
GTCGCTTCGCCCCGGAGTTGAAGAAGACCAAATACGCCAAGGAAATGTGGGCGCTGTACGAAGCGGGTACGTTGCACCCG
GCCAGCGTGCTGACTGGCGAGTTCGACGATCCCGAGGACCTGGCCGATGTCGGCGGGGTGCTGCGCGAGATCGAAGCGGC
GCGTCTGGATGAGGAGCGCAAGCAAGCCATCCGCGCGGCGGACGACGAGCCCAAGGGCAAGTCCGACGAACCGCCTCCGC
CACCGTGGATGCAGTGA

Upstream 100 bases:

>100_bases
TCAGGTTCACAGGTCGGCAACCCCTCCCCGCGATGCGAGGATTGCCGTATAACGAGTGACATTCGCGTGTTTGGTAATAA
AGGACCCACAATAAAAGCTG

Downstream 100 bases:

>100_bases
GCATCTGAAAAAGAAAACCCGGCTTCGGCCGGGTTTTACACATTCAAGGATTGATTGTGACCACCACCTCCCGCAATGCC
CGGCTGATCATCACGGCCCG

Product: hypothetical protein

Products: NA

Alternate protein names: AfRio2 [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNQLRCAKVYKEANKRSFRQAAEYQEGRKVRNSRQARAMAKGSK
FGRKEAEDAWQNAEVAALFRLANAGVRVPKPYDFLEGVLLMELVADEYGDAAPRLNDVVLEPDQAREYHAFLISQIVLML
CTGLVHGDLSEFNVLLTPTGPVIIDLPQAVDAAGNNHAFSMLERDVGNMASYFGRFAPELKKTKYAKEMWALYEAGTLHP
ASVLTGEFDDPEDLADVGGVLREIEAARLDEERKQAIRAADDEPKGKSDEPPPPPWMQ

Sequences:

>Translated_298_residues
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNQLRCAKVYKEANKRSFRQAAEYQEGRKVRNSRQARAMAKGSK
FGRKEAEDAWQNAEVAALFRLANAGVRVPKPYDFLEGVLLMELVADEYGDAAPRLNDVVLEPDQAREYHAFLISQIVLML
CTGLVHGDLSEFNVLLTPTGPVIIDLPQAVDAAGNNHAFSMLERDVGNMASYFGRFAPELKKTKYAKEMWALYEAGTLHP
ASVLTGEFDDPEDLADVGGVLREIEAARLDEERKQAIRAADDEPKGKSDEPPPPPWMQ
>Mature_298_residues
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNQLRCAKVYKEANKRSFRQAAEYQEGRKVRNSRQARAMAKGSK
FGRKEAEDAWQNAEVAALFRLANAGVRVPKPYDFLEGVLLMELVADEYGDAAPRLNDVVLEPDQAREYHAFLISQIVLML
CTGLVHGDLSEFNVLLTPTGPVIIDLPQAVDAAGNNHAFSMLERDVGNMASYFGRFAPELKKTKYAKEMWALYEAGTLHP
ASVLTGEFDDPEDLADVGGVLREIEAARLDEERKQAIRAADDEPKGKSDEPPPPPWMQ

Specific function: Unknown

COG id: COG1718

COG function: function code TD; Serine/threonine protein kinase involved in cell cycle control

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI23510356, Length=210, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17556977, Length=218, Percent_Identity=30.7339449541284, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24662811, Length=212, Percent_Identity=32.0754716981132, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356879, Length=212, Percent_Identity=32.0754716981132, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR018934
- InterPro:   IPR015285
- InterPro:   IPR000687
- InterPro:   IPR008266 [H]

Pfam domain/function: PF01163 RIO1; PF09202 Rio2_N [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33144; Mature: 33144

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS01245 RIO1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNQLRCAKVYKEANKRSFRQAAEY
CCCCHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
QEGRKVRNSRQARAMAKGSKFGRKEAEDAWQNAEVAALFRLANAGVRVPKPYDFLEGVLL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
MELVADEYGDAAPRLNDVVLEPDQAREYHAFLISQIVLMLCTGLVHGDLSEFNVLLTPTG
HHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEECCCC
PVIIDLPQAVDAAGNNHAFSMLERDVGNMASYFGRFAPELKKTKYAKEMWALYEAGTLHP
CEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ASVLTGEFDDPEDLADVGGVLREIEAARLDEERKQAIRAADDEPKGKSDEPPPPPWMQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTPKRIEPLIEDGLVDEVLRPLMSGKEAAVYVVRCGNQLRCAKVYKEANKRSFRQAAEY
CCCCHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
QEGRKVRNSRQARAMAKGSKFGRKEAEDAWQNAEVAALFRLANAGVRVPKPYDFLEGVLL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
MELVADEYGDAAPRLNDVVLEPDQAREYHAFLISQIVLMLCTGLVHGDLSEFNVLLTPTG
HHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEECCCC
PVIIDLPQAVDAAGNNHAFSMLERDVGNMASYFGRFAPELKKTKYAKEMWALYEAGTLHP
CEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ASVLTGEFDDPEDLADVGGVLREIEAARLDEERKQAIRAADDEPKGKSDEPPPPPWMQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]