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The map label for this gene is yegD [H]

Identifier: 77456804

GI number: 77456804

Start: 668400

End: 669674

Strand: Reverse

Name: yegD [H]

Synonym: Pfl01_0576

Alternate gene names: 77456804

Gene position: 669674-668400 (Counterclockwise)

Preceding gene: 77456807

Following gene: 77456800

Centisome position: 10.4

GC content: 62.67

Gene sequence:

>1275_bases
ATGAAAGACGCCTCTCCAGCCCGTGCCTGCGGCATCGACTTCGGCACGTCCAACTCCACCGTCGGCTGGCTGCGCCCCGG
CATGGAAACGATGATCGCGCTGGAAGACGACAAGATCACCCTGCCATCGGTGGTCTTTTTCAATATCGAAGAGCGCCGTC
CGGTATACGGCCGTCTGGCGCTGCACGAGTACCTGGAAGGCTACGAAGGCCGACTGATGCGCTCGCTCAAGAGCCTGCTC
GGTTCCAAGCTGATCAAGCACGACACCAGCGTTCTCGGCACCGCAATGCCGTTCAAGGACCTGCTCGGGCTGTTCATCGG
CCAGCTCAAGAGCCGCGCCGAAGCCGCCGCCGGTCGGGAGTTCGAGCAGGTGGTGCTGGGCCGCCCGGTGTTCTTCGTCG
ACGACGATCCGCTGGCCGACCAGGAAGCCGAAGACACCCTGGTGGAAGTGGCGCGCAAACTCGGTTTCAAGGACGTGTCG
TTCCAGTACGAGCCGATTGCCGCGGCCTTCGACTACGAGTCGACCATCGAAAAGGAAGAACTGGTGCTGATCGTCGACAT
CGGCGGTGGTACGTCGGACTTCTCGCTGGTGCGCCTGTCGCCCGAGCGTCGTGGTGTGGATAATCGCCACGACGACATCC
TCGCCACCGGCGGCGTGCACATCGGCGGGACCGACTTCGACAAACAGTTGAGCCTGCAAGGCCTGATGCCGCTGTTCGGC
TACGGCAGCCGGATGAAAAGCGGCGCGTTCATGCCGACCAGCCACCACATGAACCTGGCGACCTGGCACACCATCAACTC
GGTGTACTCGCAGAAATCGACCCTGGCCCTGGGCAGCATGCGCTACGACATCGAAGACACCGGCGGCATCGACCGTCTGT
TCAAGCTGATCGAACAGCGCGCCGGCCATTGGCTGGCGATGGAAGTGGAAGAAACCAAGATCCACCTGACCCACAACGAC
AGCCGCCATGTGCCGCTGGATCGCATCGAGCCGGGCCTGAGCGTGGAACTGACCCGGGCGCTGTTCGAATCGGCGATCGA
GTCGCAGCTCGAGCGCGTGCGCGGCAGCGTCACCCAGTTGCTGGCGGACGCCAATGTGGCGGTGGGTCAGGTCGATACGG
TGTTCTTCACCGGTGGTTCGAGCGGCATTCCGGCACTGCGCAACAGCGTCTCGGCGATGCTGCCGAACGCGCGGCATGTG
GAAGGGAATATTTTTGGCAGCATTGGTAGCGGTCTGGCGATTGAGGCCATGAAACGTTACGGCTCGGTGAACTGA

Upstream 100 bases:

>100_bases
CAAGCAAGCTTAGTCGTGAAATAGCAGATGACCGGCCTTCGAATCTGTCGCGCACTGACATACACTGCGCGGCCGTTTTT
TTGACCGGAACCGAAAGACC

Downstream 100 bases:

>100_bases
CACTGCACTGATGATCGTTCCCACGCTCTGCGTGGGAATGCCGCAATGGACGCTCTGCGTCCGCTGTTGAAGCTGTGACG
CGGAGCGTCACGGGATGCAT

Product: heat shock protein YegD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MKDASPARACGIDFGTSNSTVGWLRPGMETMIALEDDKITLPSVVFFNIEERRPVYGRLALHEYLEGYEGRLMRSLKSLL
GSKLIKHDTSVLGTAMPFKDLLGLFIGQLKSRAEAAAGREFEQVVLGRPVFFVDDDPLADQEAEDTLVEVARKLGFKDVS
FQYEPIAAAFDYESTIEKEELVLIVDIGGGTSDFSLVRLSPERRGVDNRHDDILATGGVHIGGTDFDKQLSLQGLMPLFG
YGSRMKSGAFMPTSHHMNLATWHTINSVYSQKSTLALGSMRYDIEDTGGIDRLFKLIEQRAGHWLAMEVEETKIHLTHND
SRHVPLDRIEPGLSVELTRALFESAIESQLERVRGSVTQLLADANVAVGQVDTVFFTGGSSGIPALRNSVSAMLPNARHV
EGNIFGSIGSGLAIEAMKRYGSVN

Sequences:

>Translated_424_residues
MKDASPARACGIDFGTSNSTVGWLRPGMETMIALEDDKITLPSVVFFNIEERRPVYGRLALHEYLEGYEGRLMRSLKSLL
GSKLIKHDTSVLGTAMPFKDLLGLFIGQLKSRAEAAAGREFEQVVLGRPVFFVDDDPLADQEAEDTLVEVARKLGFKDVS
FQYEPIAAAFDYESTIEKEELVLIVDIGGGTSDFSLVRLSPERRGVDNRHDDILATGGVHIGGTDFDKQLSLQGLMPLFG
YGSRMKSGAFMPTSHHMNLATWHTINSVYSQKSTLALGSMRYDIEDTGGIDRLFKLIEQRAGHWLAMEVEETKIHLTHND
SRHVPLDRIEPGLSVELTRALFESAIESQLERVRGSVTQLLADANVAVGQVDTVFFTGGSSGIPALRNSVSAMLPNARHV
EGNIFGSIGSGLAIEAMKRYGSVN
>Mature_424_residues
MKDASPARACGIDFGTSNSTVGWLRPGMETMIALEDDKITLPSVVFFNIEERRPVYGRLALHEYLEGYEGRLMRSLKSLL
GSKLIKHDTSVLGTAMPFKDLLGLFIGQLKSRAEAAAGREFEQVVLGRPVFFVDDDPLADQEAEDTLVEVARKLGFKDVS
FQYEPIAAAFDYESTIEKEELVLIVDIGGGTSDFSLVRLSPERRGVDNRHDDILATGGVHIGGTDFDKQLSLQGLMPLFG
YGSRMKSGAFMPTSHHMNLATWHTINSVYSQKSTLALGSMRYDIEDTGGIDRLFKLIEQRAGHWLAMEVEETKIHLTHND
SRHVPLDRIEPGLSVELTRALFESAIESQLERVRGSVTQLLADANVAVGQVDTVFFTGGSSGIPALRNSVSAMLPNARHV
EGNIFGSIGSGLAIEAMKRYGSVN

Specific function: Unknown

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Escherichia coli, GI87082035, Length=449, Percent_Identity=29.3986636971047, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1788875, Length=245, Percent_Identity=29.7959183673469, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17507981, Length=412, Percent_Identity=25, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17534015, Length=412, Percent_Identity=24.0291262135922, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534013, Length=412, Percent_Identity=24.0291262135922, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534771, Length=440, Percent_Identity=23.8636363636364, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322426, Length=436, Percent_Identity=24.5412844036697, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322505, Length=413, Percent_Identity=23.4866828087167, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320950, Length=412, Percent_Identity=24.7572815533981, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320805, Length=446, Percent_Identity=22.4215246636771, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641406, Length=444, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641408, Length=444, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641402, Length=444, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641404, Length=444, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 46523; Mature: 46523

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDASPARACGIDFGTSNSTVGWLRPGMETMIALEDDKITLPSVVFFNIEERRPVYGRLA
CCCCCCCCEECCCCCCCCCCCEEECCCCEEEEEECCCCEECCEEEEEEECCCCCHHHHHH
LHEYLEGYEGRLMRSLKSLLGSKLIKHDTSVLGTAMPFKDLLGLFIGQLKSRAEAAAGRE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
FEQVVLGRPVFFVDDDPLADQEAEDTLVEVARKLGFKDVSFQYEPIAAAFDYESTIEKEE
HHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCEEEECCCHHHCCCCC
LVLIVDIGGGTSDFSLVRLSPERRGVDNRHDDILATGGVHIGGTDFDKQLSLQGLMPLFG
EEEEEECCCCCCCCEEEEECHHHCCCCCCCCCEEEECCEEECCCCCCHHHHHHHCCHHHC
YGSRMKSGAFMPTSHHMNLATWHTINSVYSQKSTLALGSMRYDIEDTGGIDRLFKLIEQR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHEEECCEEECCCCCCCHHHHHHHHHHH
AGHWLAMEVEETKIHLTHNDSRHVPLDRIEPGLSVELTRALFESAIESQLERVRGSVTQL
CCCEEEEEEEEEEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LADANVAVGQVDTVFFTGGSSGIPALRNSVSAMLPNARHVEGNIFGSIGSGLAIEAMKRY
HHCCCCEECCEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCEEEECCCCCHHHHHHHHC
GSVN
CCCC
>Mature Secondary Structure
MKDASPARACGIDFGTSNSTVGWLRPGMETMIALEDDKITLPSVVFFNIEERRPVYGRLA
CCCCCCCCEECCCCCCCCCCCEEECCCCEEEEEECCCCEECCEEEEEEECCCCCHHHHHH
LHEYLEGYEGRLMRSLKSLLGSKLIKHDTSVLGTAMPFKDLLGLFIGQLKSRAEAAAGRE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
FEQVVLGRPVFFVDDDPLADQEAEDTLVEVARKLGFKDVSFQYEPIAAAFDYESTIEKEE
HHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCEEEECCCHHHCCCCC
LVLIVDIGGGTSDFSLVRLSPERRGVDNRHDDILATGGVHIGGTDFDKQLSLQGLMPLFG
EEEEEECCCCCCCCEEEEECHHHCCCCCCCCCEEEECCEEECCCCCCHHHHHHHCCHHHC
YGSRMKSGAFMPTSHHMNLATWHTINSVYSQKSTLALGSMRYDIEDTGGIDRLFKLIEQR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHEEECCEEECCCCCCCHHHHHHHHHHH
AGHWLAMEVEETKIHLTHNDSRHVPLDRIEPGLSVELTRALFESAIESQLERVRGSVTQL
CCCEEEEEEEEEEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LADANVAVGQVDTVFFTGGSSGIPALRNSVSAMLPNARHVEGNIFGSIGSGLAIEAMKRY
HHCCCCEECCEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCEEEECCCCCHHHHHHHHC
GSVN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7940673; 7984428 [H]