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The map label for this gene is cysC [H]

Identifier: 77456711

GI number: 77456711

Start: 560254

End: 560865

Strand: Direct

Name: cysC [H]

Synonym: Pfl01_0483

Alternate gene names: 77456711

Gene position: 560254-560865 (Clockwise)

Preceding gene: 77456710

Following gene: 77456712

Centisome position: 8.7

GC content: 63.89

Gene sequence:

>612_bases
ATGAATGAGGCGCTGCACAGTCTGGCGACAACGCCCGCCATCAGCCCCTATAACCTGGCGCTGCCGCGCCAGGCCCGGGC
CGCGCTCAACGGGCAGCGGCCGCGTTGCCTGTGGCTGACCGGATTATCCGGCGCCGGCAAGTCGACCCTGGCCAATTCGC
TGGAGCTGCACCTGCATCAATTCGGGCGGCACACCTTTCTGCTCGATGGCGACAACGTGCGCAATGGCCTGTGCCGGGAC
CTGGGTATGGACGATGCCGGTCGCCGGGAAAACATCCGGCGCATGGCCGAAGTCGCCCGGCTGATGGTCGATGCCGGGCT
GATCGTCATCGTTGCGGCGATTTCCCCGTTTCGAGCCGAACGGGATGCTGCGCGGCGACTGTTTGCCGAGGGCGACTTCG
TCGAAGTGCATGTGAGCACTTCGCTCACGGTGTGCGAGCGCCGTGATCCGAAAGGTTTGTATCAGGCGGTGCGTCAGGGT
CGTATCCAGCATTTCACGGGCATCGACAGTCCTTACGAGGCTCCGCTGGCGGCGGAATGCCGTATCGACACGGAAGAGAT
CGAGCCAAGCGAGGCCTGCGAACGGCTGGCGGCTTTGCTGCTTGAAAAATGA

Upstream 100 bases:

>100_bases
TCGCGGCAACGTCAACCACTGAAGGCGCGGGAGTTCTGCTCGGCGCGAACCCGTCGGCTGGTGCGTCGGGCCTATCAGCG
CGACTACGAGTTGCTCGGTT

Downstream 100 bases:

>100_bases
GCAAAAAAGCCAGCTGTTTCATCCTGTTGCAGCCACCGCACAAGCCTTCGCCAACCCTGTGTTAATATCGCGCCCCTGTT
CATTTTGTATGTGGGTTGCT

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MNEALHSLATTPAISPYNLALPRQARAALNGQRPRCLWLTGLSGAGKSTLANSLELHLHQFGRHTFLLDGDNVRNGLCRD
LGMDDAGRRENIRRMAEVARLMVDAGLIVIVAAISPFRAERDAARRLFAEGDFVEVHVSTSLTVCERRDPKGLYQAVRQG
RIQHFTGIDSPYEAPLAAECRIDTEEIEPSEACERLAALLLEK

Sequences:

>Translated_203_residues
MNEALHSLATTPAISPYNLALPRQARAALNGQRPRCLWLTGLSGAGKSTLANSLELHLHQFGRHTFLLDGDNVRNGLCRD
LGMDDAGRRENIRRMAEVARLMVDAGLIVIVAAISPFRAERDAARRLFAEGDFVEVHVSTSLTVCERRDPKGLYQAVRQG
RIQHFTGIDSPYEAPLAAECRIDTEEIEPSEACERLAALLLEK
>Mature_203_residues
MNEALHSLATTPAISPYNLALPRQARAALNGQRPRCLWLTGLSGAGKSTLANSLELHLHQFGRHTFLLDGDNVRNGLCRD
LGMDDAGRRENIRRMAEVARLMVDAGLIVIVAAISPFRAERDAARRLFAEGDFVEVHVSTSLTVCERRDPKGLYQAVRQG
RIQHFTGIDSPYEAPLAAECRIDTEEIEPSEACERLAALLLEK

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=182, Percent_Identity=45.0549450549451, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI62912492, Length=182, Percent_Identity=45.0549450549451, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI34447231, Length=182, Percent_Identity=45.0549450549451, Blast_Score=149, Evalue=2e-36,
Organism=Escherichia coli, GI1789107, Length=164, Percent_Identity=57.9268292682927, Blast_Score=195, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17542422, Length=170, Percent_Identity=50, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322852, Length=184, Percent_Identity=45.6521739130435, Blast_Score=156, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24667032, Length=172, Percent_Identity=44.7674418604651, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24667028, Length=172, Percent_Identity=44.7674418604651, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24667036, Length=172, Percent_Identity=44.7674418604651, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI116007838, Length=172, Percent_Identity=44.7674418604651, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24667044, Length=172, Percent_Identity=44.7674418604651, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24667040, Length=172, Percent_Identity=44.7674418604651, Blast_Score=148, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 22414; Mature: 22414

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEALHSLATTPAISPYNLALPRQARAALNGQRPRCLWLTGLSGAGKSTLANSLELHLHQ
CCHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
FGRHTFLLDGDNVRNGLCRDLGMDDAGRRENIRRMAEVARLMVDAGLIVIVAAISPFRAE
CCCEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
RDAARRLFAEGDFVEVHVSTSLTVCERRDPKGLYQAVRQGRIQHFTGIDSPYEAPLAAEC
HHHHHHHHCCCCEEEEEECCCEEEECCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCEEEE
RIDTEEIEPSEACERLAALLLEK
ECCHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNEALHSLATTPAISPYNLALPRQARAALNGQRPRCLWLTGLSGAGKSTLANSLELHLHQ
CCHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
FGRHTFLLDGDNVRNGLCRDLGMDDAGRRENIRRMAEVARLMVDAGLIVIVAAISPFRAE
CCCEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
RDAARRLFAEGDFVEVHVSTSLTVCERRDPKGLYQAVRQGRIQHFTGIDSPYEAPLAAEC
HHHHHHHHCCCCEEEEEECCCEEEECCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCEEEE
RIDTEEIEPSEACERLAALLLEK
ECCHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]