BacMap

Definition	Pseudomonas fluorescens Pf0-1 chromosome, complete genome.
Accession	NC_007492
Length	6,438,405

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The map label for this gene is fabG [H]

Identifier: 77456651

GI number: 77456651

Start: 482728

End: 483456

Strand: Reverse

Name: fabG [H]

Synonym: Pfl01_0423

Alternate gene names: 77456651

Gene position: 483456-482728 (Counterclockwise)

Preceding gene: 77456652

Following gene: 77456650

Centisome position: 7.51

GC content: 63.37

Gene sequence:

>729_bases
ATGACTGAATCCATCCTGGTCACCGGCTCCAGCCGTGGCATCGGCCGCGCCATCGCCCTGCGCCTGGCCAGCGCCGGCCA
CGATATCGTCCTGCATTGCCGCAGCGGCGTGACGGAAGCACAAGCAGTGAAAGCCGAAGTCGAAGCCCTCGGCCGCACCG
CGCGCATCCTGCAATTCGACGTGGCGGATCGCGAAACCTGCAAAGCCATCCTCGAAGCCGACGTTGAAGCCCACGGTGCC
TACTACGGCGTGGTGCTCAATGCCGGGCTGACCCGCGACGGTGCCTTTCCGGCCCTGAGCGACGATGACTGGGACGTAGT
GCTGCGCACCAACCTCGACGGTTTCTACAACGTCCTGCACCCGGTGATGATGCCGATGATCCGCCGCCGCGCCGCTGGTC
GCATCGTTTGCATCACCTCGGTTTCGGGGCTGATCGGCAACCGTGGCCAAGTCAATTACAGCGCCTCGAAGGCCGGCGTG
ATCGGCGCGGCAAAGGCGTTGGCGATCGAACTGGCCAAGCGCAAAATCACGGTGAATTGCGTCGCGCCCGGTCTGATCGA
TACCGCCATGCTCGATGAAAACGTGCCGGTGGAAGAACTGCTGAAAATGATCCCCGCACAACGCATGGGCACGCCTGAAG
AGGTGGCCGGTGCGGTGAATTTCCTGATGTCGGCGGAAGCGTCGTACATCACCCGCCAGGTGCTGGCGGTCAACGGAGGC
TTGTGCTGA

Upstream 100 bases:

>100_bases
TGCCATATCAATGCGCCCGGCATCGAGGCCAGCGCCCGGTTGAACGTGTTCCGCCCGCCCCAGGCAGCGGACTATCTGGA
ACAATCCAAGGAGTCGAACG

Downstream 100 bases:

>100_bases
TGAAGCGCGTCGTCGTCACCGGCATGGCCGGCATTACCTCGCTGGGCAGCGACTGGGACACCATCGCCGGCAATTTCGCC
GCCAACCGCAGCGGCATCCG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTESILVTGSSRGIGRAIALRLASAGHDIVLHCRSGVTEAQAVKAEVEALGRTARILQFDVADRETCKAILEADVEAHGA
YYGVVLNAGLTRDGAFPALSDDDWDVVLRTNLDGFYNVLHPVMMPMIRRRAAGRIVCITSVSGLIGNRGQVNYSASKAGV
IGAAKALAIELAKRKITVNCVAPGLIDTAMLDENVPVEELLKMIPAQRMGTPEEVAGAVNFLMSAEASYITRQVLAVNGG
LC

Sequences:

>Translated_242_residues
MTESILVTGSSRGIGRAIALRLASAGHDIVLHCRSGVTEAQAVKAEVEALGRTARILQFDVADRETCKAILEADVEAHGA
YYGVVLNAGLTRDGAFPALSDDDWDVVLRTNLDGFYNVLHPVMMPMIRRRAAGRIVCITSVSGLIGNRGQVNYSASKAGV
IGAAKALAIELAKRKITVNCVAPGLIDTAMLDENVPVEELLKMIPAQRMGTPEEVAGAVNFLMSAEASYITRQVLAVNGG
LC
>Mature_241_residues
TESILVTGSSRGIGRAIALRLASAGHDIVLHCRSGVTEAQAVKAEVEALGRTARILQFDVADRETCKAILEADVEAHGAY
YGVVLNAGLTRDGAFPALSDDDWDVVLRTNLDGFYNVLHPVMMPMIRRRAAGRIVCITSVSGLIGNRGQVNYSASKAGVI
GAAKALAIELAKRKITVNCVAPGLIDTAMLDENVPVEELLKMIPAQRMGTPEEVAGAVNFLMSAEASYITRQVLAVNGGL
C

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=37.5, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=39.2561983471074, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=36.3636363636364, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4504505, Length=226, Percent_Identity=34.070796460177, Blast_Score=103, Evalue=9e-23,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=33.2, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI126723750, Length=244, Percent_Identity=32.7868852459016, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI5031737, Length=239, Percent_Identity=31.3807531380753, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI66933014, Length=169, Percent_Identity=31.3609467455621, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI59889578, Length=190, Percent_Identity=32.6315789473684, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=31.9371727748691, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=32.4022346368715, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=29.9595141700405, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=184, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=28.8557213930348, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503301, Length=228, Percent_Identity=27.6315789473684, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI223718074, Length=217, Percent_Identity=30.4147465437788, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=42.7385892116183, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=34.7107438016529, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=32.9218106995885, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1789208, Length=239, Percent_Identity=33.4728033472803, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=29.6296296296296, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=29.3388429752066, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=33.6099585062241, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=30.4, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=29.4605809128631, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786701, Length=198, Percent_Identity=30.8080808080808, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787526, Length=228, Percent_Identity=28.5087719298246, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=37.2950819672131, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=35.4166666666667, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=32.0158102766798, Blast_Score=106, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17568967, Length=186, Percent_Identity=32.258064516129, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=31.2757201646091, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=29.3877551020408, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=28.8617886178862, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=28.0487804878049, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=244, Percent_Identity=28.6885245901639, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=30.2564102564103, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=27.7992277992278, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=198, Percent_Identity=26.2626262626263, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=243, Percent_Identity=27.5720164609054, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=256, Percent_Identity=26.5625, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=25.6809338521401, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=199, Percent_Identity=28.643216080402, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=255, Percent_Identity=29.0196078431373, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=213, Percent_Identity=26.7605633802817, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=213, Percent_Identity=26.7605633802817, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=27.0833333333333, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=245, Percent_Identity=29.7959183673469, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324126, Length=190, Percent_Identity=30, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=202, Percent_Identity=28.7128712871287, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=36.2139917695473, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=34.7107438016529, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=31.0204081632653, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=32.3770491803279, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=32.3770491803279, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=31.9672131147541, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=31.25, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=32.8042328042328, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI116007236, Length=230, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17737361, Length=251, Percent_Identity=31.0756972111554, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25633; Mature: 25502

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESILVTGSSRGIGRAIALRLASAGHDIVLHCRSGVTEAQAVKAEVEALGRTARILQFD
CCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHEEEEEE
VADRETCKAILEADVEAHGAYYGVVLNAGLTRDGAFPALSDDDWDVVLRTNLDGFYNVLH
CCCHHHHHHHHHHCHHHCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHH
PVMMPMIRRRAAGRIVCITSVSGLIGNRGQVNYSASKAGVIGAAKALAIELAKRKITVNC
HHHHHHHHHHHCCCEEEEEECHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHEEEEEE
VAPGLIDTAMLDENVPVEELLKMIPAQRMGTPEEVAGAVNFLMSAEASYITRQVLAVNGG
ECCCHHHHHHHCCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LC
CC
>Mature Secondary Structure 
TESILVTGSSRGIGRAIALRLASAGHDIVLHCRSGVTEAQAVKAEVEALGRTARILQFD
CCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHEEEEEE
VADRETCKAILEADVEAHGAYYGVVLNAGLTRDGAFPALSDDDWDVVLRTNLDGFYNVLH
CCCHHHHHHHHHHCHHHCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHH
PVMMPMIRRRAAGRIVCITSVSGLIGNRGQVNYSASKAGVIGAAKALAIELAKRKITVNC
HHHHHHHHHHHCCCEEEEEECHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHEEEEEE
VAPGLIDTAMLDENVPVEELLKMIPAQRMGTPEEVAGAVNFLMSAEASYITRQVLAVNGG
ECCCHHHHHHHCCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LC
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]