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The map label for this gene is aaeB [H]

Identifier: 77456399

GI number: 77456399

Start: 205566

End: 207629

Strand: Direct

Name: aaeB [H]

Synonym: Pfl01_0171

Alternate gene names: 77456399

Gene position: 205566-207629 (Clockwise)

Preceding gene: 77456398

Following gene: 77456400

Centisome position: 3.19

GC content: 63.71

Gene sequence:

>2064_bases
GTGAACGGGTTCTTTTCCGGCATGCCCCCCGCGCGGGACTGGTTCTACGGGATCCGCACGTTCGCGGCCTCGATGACCGC
GCTGTACATCGCCTTGCTCATGCAGATGCCGCGTCCGTACTGGGCGATGGCCACGGTGTACATCGTTTCCAGTCCGTTCC
TCGGCCCGACCAGTTCCAAGGCGCTGTATCGGGCGATCGGCACGTTTCTCGGTGCAGCGGCGGCGGTGCTGTTCGTGCCG
ATGTTCGTCCAGAGCCCGTACGTGCTGGTGGTGGTCATCGCCTTGTGGACGGGGATTCTGCTGTTCCTGTCCCTGCACCT
GCGCACCGCCAACAACTACGCGCTGATGCTGGCCGGCTACACCTTGCCGTTGATCGCTCTACCGGTGGTGGATAACCCGC
TGGCGGTGTGGGACGTGGCCGAGTCGCGAACTGAAGAGATCTTCCTCGGCATCGCCGTGGCGGCGGTGGTCGGTGCGATG
TTCTGGCCACGGCGCCTGGCACCGGTGTTCAACGATGCCGTGGGCAAATGGTTCGCCGACGCCACGACCTACAGCCTGAA
ATTCCTCAGCCGCGACGTGCAGCCCGAAGCGGTCGCAGCCCTGCGCATGGCAATGGTCGGCAGTTTCAACAGCCTGGAAT
TGATGATCGGCCAGTTGCCGCACGAAGGTGCGCGTCCGCAGACGGTGCGCAACACCAAGGAACTGCGCGGGCGGATGATC
CACCTGCTGCCGGTGATCGACGCCCTTGAAGACTCGCTTTACGCCCTCGAACGGCGCACGCCCGAGCTGGTGGAAAAGTT
CGCACCACTGCTCATCTCGACCCGCGAATGGCTTGGCCACAAAGACGCCGATCTGGAACGCTGGCAAGCGCTGCGGGATC
AGCTCGAAGCGCTGCAACCGAGCGCCGAAGCCCTCGAAGATCGCAAGCAGTTGCTGTTTTCCAACGCGCTGTATCGCCTC
GGCGAGTTCATCGATCTGTGGCAGGACTGCCGCAGCCTGCAGGACGCAATCCTGTGCGAGCGCCAGGACAGCTGGCGCGC
GGTCTATCGTCACTGGCGCCTCGGTCGCCTGACGCCATTCATCGACCGCGGGCTGATGTTGTATTCGGTGGCCTCGACCA
TCCTGGCGATCATCGTCGCTTCGGTACTGTGGATCCTGCTGGGCTGGACCGACGGCGGCAGCGCGGTGATTCTGGCGGCG
GTGTCGTGCAGTTTCTTCGCCTCGATGGACGACCCGGCGCCGCAGATCTACCGGTTCTTTTTCTGGACCGGGATGTCGGT
GCTGTTCGCCAGCCTGTACCTGTTTCTGGTGTTGCCGAACCTGCATGACTTTCCGATGCTGGTGCTGGCGTTCGCGGTGC
CGTTCATCTGTGTCGGCACCCTGACGGTGCAGCCCCGTTTCTACCTCGGCATGCTGCTGACGCTGGTCAACACCTCGTCG
TTCATCAGTATTTCCGGTGCTTACGACGCGGACTTCTTTGCCTTCGTCAATTCCAACCTGGCGGGCCCGATTGGGTTGTT
GTTCGCGTTTATCTGGACCCTGATCGCCCGGCCGTTCGGCGCCGAACTGGCGGCCAAACGCCTGACCCGTTTCAGCTGGA
AAGACATCGTCAGCATGACCGAACCGGCGAACCTCGCCGAACATCGACAACTCGGCGTGCAATTGCTCGACCGCCTGATG
CAGCACCTGCCGCGTCTGGCGCTGACCGGGCAGGACACCGGCATCGCCATGCGCGAAGTGCGCGTGGGGCTGAACCTGCT
CGACCTGCTCGCCTATACGCCGCGAGTGACGGGCGCGCCGAACGCGCTGCTCAAGCAAGTAGTGGCTGAGGTTGGCGAGT
ATTTCCGGGCCTGTCTCAAGGCCGGGGAACGCCTGCCGGCGCCGAGCGCCCTGCTGATGACCATGGATCGCACCCGCCGT
GCGCTCAGCGGCCACGGCGATGAAGACACCCGACTCAACCTGTTGCATGCCTTGAGCGGTTTGCGCCTGGCGCTGTTGCC
CGGCGTGGAATTCGTTTCCAACGCAGAGCCCGAAGAACCGCTGCCCGAAGGAGCGCCCCTATGA

Upstream 100 bases:

>100_bases
GTCATGAAGTGCTCGAAGGCATCGACCAGCGCGATCTGGAGGCTACGCTTCGAGTACTGAGAGCTTTCGAGGCGGCCACT
CCGCCAACGGTGATCAATCC

Downstream 100 bases:

>100_bases
TCGGTGATCTGGACATCAGCGGCATATTCCTGCCGACCCTGCTGGTGTTGATGGGCATCACTTATGTGCTGTTTGTGTTG
GTACACGGCGTGCTCACACG

Product: fusaric acid resistance protein

Products: NA

Alternate protein names: pHBA efflux pump protein B [H]

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MNGFFSGMPPARDWFYGIRTFAASMTALYIALLMQMPRPYWAMATVYIVSSPFLGPTSSKALYRAIGTFLGAAAAVLFVP
MFVQSPYVLVVVIALWTGILLFLSLHLRTANNYALMLAGYTLPLIALPVVDNPLAVWDVAESRTEEIFLGIAVAAVVGAM
FWPRRLAPVFNDAVGKWFADATTYSLKFLSRDVQPEAVAALRMAMVGSFNSLELMIGQLPHEGARPQTVRNTKELRGRMI
HLLPVIDALEDSLYALERRTPELVEKFAPLLISTREWLGHKDADLERWQALRDQLEALQPSAEALEDRKQLLFSNALYRL
GEFIDLWQDCRSLQDAILCERQDSWRAVYRHWRLGRLTPFIDRGLMLYSVASTILAIIVASVLWILLGWTDGGSAVILAA
VSCSFFASMDDPAPQIYRFFFWTGMSVLFASLYLFLVLPNLHDFPMLVLAFAVPFICVGTLTVQPRFYLGMLLTLVNTSS
FISISGAYDADFFAFVNSNLAGPIGLLFAFIWTLIARPFGAELAAKRLTRFSWKDIVSMTEPANLAEHRQLGVQLLDRLM
QHLPRLALTGQDTGIAMREVRVGLNLLDLLAYTPRVTGAPNALLKQVVAEVGEYFRACLKAGERLPAPSALLMTMDRTRR
ALSGHGDEDTRLNLLHALSGLRLALLPGVEFVSNAEPEEPLPEGAPL

Sequences:

>Translated_687_residues
MNGFFSGMPPARDWFYGIRTFAASMTALYIALLMQMPRPYWAMATVYIVSSPFLGPTSSKALYRAIGTFLGAAAAVLFVP
MFVQSPYVLVVVIALWTGILLFLSLHLRTANNYALMLAGYTLPLIALPVVDNPLAVWDVAESRTEEIFLGIAVAAVVGAM
FWPRRLAPVFNDAVGKWFADATTYSLKFLSRDVQPEAVAALRMAMVGSFNSLELMIGQLPHEGARPQTVRNTKELRGRMI
HLLPVIDALEDSLYALERRTPELVEKFAPLLISTREWLGHKDADLERWQALRDQLEALQPSAEALEDRKQLLFSNALYRL
GEFIDLWQDCRSLQDAILCERQDSWRAVYRHWRLGRLTPFIDRGLMLYSVASTILAIIVASVLWILLGWTDGGSAVILAA
VSCSFFASMDDPAPQIYRFFFWTGMSVLFASLYLFLVLPNLHDFPMLVLAFAVPFICVGTLTVQPRFYLGMLLTLVNTSS
FISISGAYDADFFAFVNSNLAGPIGLLFAFIWTLIARPFGAELAAKRLTRFSWKDIVSMTEPANLAEHRQLGVQLLDRLM
QHLPRLALTGQDTGIAMREVRVGLNLLDLLAYTPRVTGAPNALLKQVVAEVGEYFRACLKAGERLPAPSALLMTMDRTRR
ALSGHGDEDTRLNLLHALSGLRLALLPGVEFVSNAEPEEPLPEGAPL
>Mature_687_residues
MNGFFSGMPPARDWFYGIRTFAASMTALYIALLMQMPRPYWAMATVYIVSSPFLGPTSSKALYRAIGTFLGAAAAVLFVP
MFVQSPYVLVVVIALWTGILLFLSLHLRTANNYALMLAGYTLPLIALPVVDNPLAVWDVAESRTEEIFLGIAVAAVVGAM
FWPRRLAPVFNDAVGKWFADATTYSLKFLSRDVQPEAVAALRMAMVGSFNSLELMIGQLPHEGARPQTVRNTKELRGRMI
HLLPVIDALEDSLYALERRTPELVEKFAPLLISTREWLGHKDADLERWQALRDQLEALQPSAEALEDRKQLLFSNALYRL
GEFIDLWQDCRSLQDAILCERQDSWRAVYRHWRLGRLTPFIDRGLMLYSVASTILAIIVASVLWILLGWTDGGSAVILAA
VSCSFFASMDDPAPQIYRFFFWTGMSVLFASLYLFLVLPNLHDFPMLVLAFAVPFICVGTLTVQPRFYLGMLLTLVNTSS
FISISGAYDADFFAFVNSNLAGPIGLLFAFIWTLIARPFGAELAAKRLTRFSWKDIVSMTEPANLAEHRQLGVQLLDRLM
QHLPRLALTGQDTGIAMREVRVGLNLLDLLAYTPRVTGAPNALLKQVVAEVGEYFRACLKAGERLPAPSALLMTMDRTRR
ALSGHGDEDTRLNLLHALSGLRLALLPGVEFVSNAEPEEPLPEGAPL

Specific function: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1789636, Length=595, Percent_Identity=23.5294117647059, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1787933, Length=592, Percent_Identity=26.0135135135135, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 76402; Mature: 76402

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFFSGMPPARDWFYGIRTFAASMTALYIALLMQMPRPYWAMATVYIVSSPFLGPTSSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHH
ALYRAIGTFLGAAAAVLFVPMFVQSPYVLVVVIALWTGILLFLSLHLRTANNYALMLAGY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
TLPLIALPVVDNPLAVWDVAESRTEEIFLGIAVAAVVGAMFWPRRLAPVFNDAVGKWFAD
HHHHHEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATTYSLKFLSRDVQPEAVAALRMAMVGSFNSLELMIGQLPHEGARPQTVRNTKELRGRMI
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
HLLPVIDALEDSLYALERRTPELVEKFAPLLISTREWLGHKDADLERWQALRDQLEALQP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
SAEALEDRKQLLFSNALYRLGEFIDLWQDCRSLQDAILCERQDSWRAVYRHWRLGRLTPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH
IDRGLMLYSVASTILAIIVASVLWILLGWTDGGSAVILAAVSCSFFASMDDPAPQIYRFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
FWTGMSVLFASLYLFLVLPNLHDFPMLVLAFAVPFICVGTLTVQPRFYLGMLLTLVNTSS
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCCC
FISISGAYDADFFAFVNSNLAGPIGLLFAFIWTLIARPFGAELAAKRLTRFSWKDIVSMT
EEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
EPANLAEHRQLGVQLLDRLMQHLPRLALTGQDTGIAMREVRVGLNLLDLLAYTPRVTGAP
CCCCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
NALLKQVVAEVGEYFRACLKAGERLPAPSALLMTMDRTRRALSGHGDEDTRLNLLHALSG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
LRLALLPGVEFVSNAEPEEPLPEGAPL
CHHHHHCCHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNGFFSGMPPARDWFYGIRTFAASMTALYIALLMQMPRPYWAMATVYIVSSPFLGPTSSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHH
ALYRAIGTFLGAAAAVLFVPMFVQSPYVLVVVIALWTGILLFLSLHLRTANNYALMLAGY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
TLPLIALPVVDNPLAVWDVAESRTEEIFLGIAVAAVVGAMFWPRRLAPVFNDAVGKWFAD
HHHHHEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATTYSLKFLSRDVQPEAVAALRMAMVGSFNSLELMIGQLPHEGARPQTVRNTKELRGRMI
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
HLLPVIDALEDSLYALERRTPELVEKFAPLLISTREWLGHKDADLERWQALRDQLEALQP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
SAEALEDRKQLLFSNALYRLGEFIDLWQDCRSLQDAILCERQDSWRAVYRHWRLGRLTPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH
IDRGLMLYSVASTILAIIVASVLWILLGWTDGGSAVILAAVSCSFFASMDDPAPQIYRFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
FWTGMSVLFASLYLFLVLPNLHDFPMLVLAFAVPFICVGTLTVQPRFYLGMLLTLVNTSS
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCCC
FISISGAYDADFFAFVNSNLAGPIGLLFAFIWTLIARPFGAELAAKRLTRFSWKDIVSMT
EEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
EPANLAEHRQLGVQLLDRLMQHLPRLALTGQDTGIAMREVRVGLNLLDLLAYTPRVTGAP
CCCCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
NALLKQVVAEVGEYFRACLKAGERLPAPSALLMTMDRTRRALSGHGDEDTRLNLLHALSG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
LRLALLPGVEFVSNAEPEEPLPEGAPL
CHHHHHCCHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA