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The map label for this gene is yhdA [C]

Identifier: 77456359

GI number: 77456359

Start: 142534

End: 144480

Strand: Direct

Name: yhdA [C]

Synonym: Pfl01_0131

Alternate gene names: 77456359

Gene position: 142534-144480 (Clockwise)

Preceding gene: 77456358

Following gene: 77456362

Centisome position: 2.21

GC content: 63.17

Gene sequence:

>1947_bases
ATGTCTTTGTTCAAACAGCTGTTGATCGCTATCTGTCTGTTCCTGGTGGTCGCCTTCACCGGCAGCTTCATGGTCAGTCT
GGAGAGCTCGCGCACCCAGTACGTCAACCAGTTGCGCTCCCACGCCCAGGATGCGGCCACGGCGCTGGCGCTGTCGTTGA
CGCCGAACATCGATGACCCGGCGATGGTCGAGTTGCTGGTCAGTTCGATCTTCGACAGCGGTTATTACTCGAGCATCCGC
GTGGTCGATCTGAAGACCGACCAGACCATCGTCGAGCGCAACGGCATTCCGGCGGTCACCAACGTGCCCGACTGGTTCGT
CAAACTGATCGGCCTGGAACCGGCCGGTGGCGATGCGCTGGTCAGCCGTGGCTGGGAGCAGGCGGCACGGGTCGAGGTAG
TCAGCCACCCGATGTTCGCTTTGGCCAAACTCTGGCAGAGCGCACTGGGCAGCCTGGGCTGGTTGCTGGTCTGCGGCGCG
GTGAGTGCGGTGCTGGGCGCGTTGTTGTTGCGTCGGCAATTGAAGCCGCTCGATTACATGGTCAAGCAATCCCACGCCAT
CGCTCGTCGTGAGTTCCTGAGTCTGCCGGACCTGCCGCGCACGCCTGAATTGCGCCGCGTAGTGCTGGCGATGAACCAGA
TGGTCGAGAAGCTCAAGGCACTGTTCCAGGAGCAGGCCGAGCGCAGTGAAAAACTGCGTACCGAGTCCTACCAGGACAAC
CTCACAGGGTTGGCCAACCGGCGTTATTTCGAGATGCAGCTGAATGCGCGGGTGAGCAACCCGGAGCAGGCCAGTTCCGG
TTATCTGCTGCTGTTGCGGGTCAAGGATCTGGCCGGGCTGAACCAGCGCCTTGGCGGTCAGCGCACCGATGAATTGTTGA
AAGCGGTCGGCGAGCAACTGTCCCGCGAGTGCGCCAAATATCCGGAAACCCAGAACCTCGTCACCCGGATTCGCGGTGGT
GAATTCGCCGTGCTGGCGCCGGGGATGACCCGCGAAGAGGCGCTGCAACTGGCGCAGAGTCTCGACAGTGCCCTGAGCAG
CCTGTACGCGACGGGTGCCACCGACGTGGCCGCCGTGGCTTCTATCGGCCTGGCACCGTTCGCTCACGGCGATTCGCCGC
AAGCGGTCCTCAGCCTCGGCGATCAGGCGCTGGCCCAGGCCGAAGGGCAGGGCGAGCAGAACTGGGCGTGCCTCGATCAG
AGCCTGGTGGCAGACGTCGGTGACGATCACCACGCCTGGCATCGCCTGCTCGATCAGGCGTTGAATCAGCGGCGTTTCGA
GCTGTTCTTCCAGCCGGTGGTGGCGGCGCAGGACACGCAACTGGTGCTGCATTACAAGGTGCTGTCGCGCTTGCTCGACG
AGCAGGGTCAGACCATTCCCGCCGGGCGCTTCCTGCCCTGGCTGGAGCGCTTCGGCTGGACCGCGCGACTGGACCGGTTG
ATGCTCGAGCGGGTGCTGGAGCAGATGGCCGGACATGAAGAATCTTTGGCGCTGAACCTGTCCTCGGCGACCCTGGCCGA
TCCGCAGGCGTTGAACAAAGTGTTCGAGATTCTGCGGGCGCATTCCAACCTCGGAGCACGCCTGACCCTGGAAATCGGCG
AGGAACAATTGCCGGAGCAAGCGGTGCTGGAACAGCTGACCCGGCGCCTGCGCGAGCTCGGTTTCTCCCTGAGCCTGCAG
CGCTTCGGCGGACGCTTCAGCATGATCGGCAACCTGGCGCGGCTGGGGCTGGCGTACCTGAAGATCGATGGCAGCTACAT
CCGGGCGATCGATCAGGAAAGCGACAAGCGGCTGTTCATCGAAGCGATCCAGCGTGCGGCGCACAGCATCGATCTGCCGT
TGATTGCCGAACGGGTCGAGACGGAAGGGGAATTGTCGGTGATTCGCGAGATGGGGTTGTATGGGGTTCAGGGGCAGCTG
TTCGGTGAGCCAAAACCCTGGGGCTGA

Upstream 100 bases:

>100_bases
TCGGTGACACCAAACGCCTGTCACGCTGGCAGGATGTGTTGAAGAAAATGCAGGCCGAAGGATTTCCGGTCGAGACGACT
AACTAGGAGCACGCGCTCAG

Downstream 100 bases:

>100_bases
CTGATCTTTCCCACGCTCCGCGTGGGAAAGATCCAACGGATCAGATCAACCCGCCCTCATCCTCATCGATCAACTGGCTC
AACCCGCCCAGCGCTTCCCG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MSLFKQLLIAICLFLVVAFTGSFMVSLESSRTQYVNQLRSHAQDAATALALSLTPNIDDPAMVELLVSSIFDSGYYSSIR
VVDLKTDQTIVERNGIPAVTNVPDWFVKLIGLEPAGGDALVSRGWEQAARVEVVSHPMFALAKLWQSALGSLGWLLVCGA
VSAVLGALLLRRQLKPLDYMVKQSHAIARREFLSLPDLPRTPELRRVVLAMNQMVEKLKALFQEQAERSEKLRTESYQDN
LTGLANRRYFEMQLNARVSNPEQASSGYLLLLRVKDLAGLNQRLGGQRTDELLKAVGEQLSRECAKYPETQNLVTRIRGG
EFAVLAPGMTREEALQLAQSLDSALSSLYATGATDVAAVASIGLAPFAHGDSPQAVLSLGDQALAQAEGQGEQNWACLDQ
SLVADVGDDHHAWHRLLDQALNQRRFELFFQPVVAAQDTQLVLHYKVLSRLLDEQGQTIPAGRFLPWLERFGWTARLDRL
MLERVLEQMAGHEESLALNLSSATLADPQALNKVFEILRAHSNLGARLTLEIGEEQLPEQAVLEQLTRRLRELGFSLSLQ
RFGGRFSMIGNLARLGLAYLKIDGSYIRAIDQESDKRLFIEAIQRAAHSIDLPLIAERVETEGELSVIREMGLYGVQGQL
FGEPKPWG

Sequences:

>Translated_648_residues
MSLFKQLLIAICLFLVVAFTGSFMVSLESSRTQYVNQLRSHAQDAATALALSLTPNIDDPAMVELLVSSIFDSGYYSSIR
VVDLKTDQTIVERNGIPAVTNVPDWFVKLIGLEPAGGDALVSRGWEQAARVEVVSHPMFALAKLWQSALGSLGWLLVCGA
VSAVLGALLLRRQLKPLDYMVKQSHAIARREFLSLPDLPRTPELRRVVLAMNQMVEKLKALFQEQAERSEKLRTESYQDN
LTGLANRRYFEMQLNARVSNPEQASSGYLLLLRVKDLAGLNQRLGGQRTDELLKAVGEQLSRECAKYPETQNLVTRIRGG
EFAVLAPGMTREEALQLAQSLDSALSSLYATGATDVAAVASIGLAPFAHGDSPQAVLSLGDQALAQAEGQGEQNWACLDQ
SLVADVGDDHHAWHRLLDQALNQRRFELFFQPVVAAQDTQLVLHYKVLSRLLDEQGQTIPAGRFLPWLERFGWTARLDRL
MLERVLEQMAGHEESLALNLSSATLADPQALNKVFEILRAHSNLGARLTLEIGEEQLPEQAVLEQLTRRLRELGFSLSLQ
RFGGRFSMIGNLARLGLAYLKIDGSYIRAIDQESDKRLFIEAIQRAAHSIDLPLIAERVETEGELSVIREMGLYGVQGQL
FGEPKPWG
>Mature_647_residues
SLFKQLLIAICLFLVVAFTGSFMVSLESSRTQYVNQLRSHAQDAATALALSLTPNIDDPAMVELLVSSIFDSGYYSSIRV
VDLKTDQTIVERNGIPAVTNVPDWFVKLIGLEPAGGDALVSRGWEQAARVEVVSHPMFALAKLWQSALGSLGWLLVCGAV
SAVLGALLLRRQLKPLDYMVKQSHAIARREFLSLPDLPRTPELRRVVLAMNQMVEKLKALFQEQAERSEKLRTESYQDNL
TGLANRRYFEMQLNARVSNPEQASSGYLLLLRVKDLAGLNQRLGGQRTDELLKAVGEQLSRECAKYPETQNLVTRIRGGE
FAVLAPGMTREEALQLAQSLDSALSSLYATGATDVAAVASIGLAPFAHGDSPQAVLSLGDQALAQAEGQGEQNWACLDQS
LVADVGDDHHAWHRLLDQALNQRRFELFFQPVVAAQDTQLVLHYKVLSRLLDEQGQTIPAGRFLPWLERFGWTARLDRLM
LERVLEQMAGHEESLALNLSSATLADPQALNKVFEILRAHSNLGARLTLEIGEEQLPEQAVLEQLTRRLRELGFSLSLQR
FGGRFSMIGNLARLGLAYLKIDGSYIRAIDQESDKRLFIEAIQRAAHSIDLPLIAERVETEGELSVIREMGLYGVQGQLF
GEPKPWG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=668, Percent_Identity=21.8562874251497, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI87081921, Length=445, Percent_Identity=25.3932584269663, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787541, Length=446, Percent_Identity=23.7668161434978, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=24.8945147679325, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788849, Length=236, Percent_Identity=27.1186440677966, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI226510982, Length=532, Percent_Identity=24.4360902255639, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI87082096, Length=233, Percent_Identity=26.6094420600858, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=25.1046025104602, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=26.0330578512397, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788502, Length=241, Percent_Identity=26.1410788381743, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786507, Length=250, Percent_Identity=21.6, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 71787; Mature: 71656

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50885 HAMP ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFKQLLIAICLFLVVAFTGSFMVSLESSRTQYVNQLRSHAQDAATALALSLTPNIDDP
CCHHHHHHHHHHHHHHHHHCCHHEEEECHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCH
AMVELLVSSIFDSGYYSSIRVVDLKTDQTIVERNGIPAVTNVPDWFVKLIGLEPAGGDAL
HHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHCCCCCCCHHH
VSRGWEQAARVEVVSHPMFALAKLWQSALGSLGWLLVCGAVSAVLGALLLRRQLKPLDYM
HHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VKQSHAIARREFLSLPDLPRTPELRRVVLAMNQMVEKLKALFQEQAERSEKLRTESYQDN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGLANRRYFEMQLNARVSNPEQASSGYLLLLRVKDLAGLNQRLGGQRTDELLKAVGEQL
HHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEEEHHHHCHHHHHCCCCHHHHHHHHHHHH
SRECAKYPETQNLVTRIRGGEFAVLAPGMTREEALQLAQSLDSALSSLYATGATDVAAVA
HHHHHHCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SIGLAPFAHGDSPQAVLSLGDQALAQAEGQGEQNWACLDQSLVADVGDDHHAWHRLLDQA
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
LNQRRFELFFQPVVAAQDTQLVLHYKVLSRLLDEQGQTIPAGRFLPWLERFGWTARLDRL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHH
MLERVLEQMAGHEESLALNLSSATLADPQALNKVFEILRAHSNLGARLTLEIGEEQLPEQ
HHHHHHHHHCCCCHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHCCHH
AVLEQLTRRLRELGFSLSLQRFGGRFSMIGNLARLGLAYLKIDGSYIRAIDQESDKRLFI
HHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHEEECCHHHHHHCCCCCHHHHH
EAIQRAAHSIDLPLIAERVETEGELSVIREMGLYGVQGQLFGEPKPWG
HHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLFKQLLIAICLFLVVAFTGSFMVSLESSRTQYVNQLRSHAQDAATALALSLTPNIDDP
CHHHHHHHHHHHHHHHHHCCHHEEEECHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCH
AMVELLVSSIFDSGYYSSIRVVDLKTDQTIVERNGIPAVTNVPDWFVKLIGLEPAGGDAL
HHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHCCCCCCCHHH
VSRGWEQAARVEVVSHPMFALAKLWQSALGSLGWLLVCGAVSAVLGALLLRRQLKPLDYM
HHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VKQSHAIARREFLSLPDLPRTPELRRVVLAMNQMVEKLKALFQEQAERSEKLRTESYQDN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGLANRRYFEMQLNARVSNPEQASSGYLLLLRVKDLAGLNQRLGGQRTDELLKAVGEQL
HHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEEEHHHHCHHHHHCCCCHHHHHHHHHHHH
SRECAKYPETQNLVTRIRGGEFAVLAPGMTREEALQLAQSLDSALSSLYATGATDVAAVA
HHHHHHCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SIGLAPFAHGDSPQAVLSLGDQALAQAEGQGEQNWACLDQSLVADVGDDHHAWHRLLDQA
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
LNQRRFELFFQPVVAAQDTQLVLHYKVLSRLLDEQGQTIPAGRFLPWLERFGWTARLDRL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHH
MLERVLEQMAGHEESLALNLSSATLADPQALNKVFEILRAHSNLGARLTLEIGEEQLPEQ
HHHHHHHHHCCCCHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHCCHH
AVLEQLTRRLRELGFSLSLQRFGGRFSMIGNLARLGLAYLKIDGSYIRAIDQESDKRLFI
HHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHEEECCHHHHHHCCCCCHHHHH
EAIQRAAHSIDLPLIAERVETEGELSVIREMGLYGVQGQLFGEPKPWG
HHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]