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The map label for this gene is bepC [H]

Identifier: 77456362

GI number: 77456362

Start: 161000

End: 162352

Strand: Direct

Name: bepC [H]

Synonym: Pfl01_0134

Alternate gene names: 77456362

Gene position: 161000-162352 (Clockwise)

Preceding gene: 77456359

Following gene: 77456363

Centisome position: 2.5

GC content: 60.31

Gene sequence:

>1353_bases
ATGCGTTCGCACCTGTTCAAGGCTCTACCCTTCGCTCTCGCCGCGTCTTTCGTACAAGCACAATCCTTACCAGAAGCCAT
GCAGCAGGCGCTGGATGTCCATCCGGAAATCCAGGCAGGGGTCAACAGCCGACTGGCCGCGGATTATCAGTTAAAGGCTG
CAAAAGGTGGATACCTGCCCAAGGTCGATCTGCTGGGCGGTTATGGCCGTGAAGGCACCGACAGCGTCACCACCCGCGCC
AATGGTGGCGGCAATCACTGGGAAACCCTGAACCGCAGCGAGTCAAGTTTGCGTCTGTCGCAAATGGTTTTTGACGGTTT
TGCGACGTCCAGCGAAGTCGGGCGTCAACAAGCCACCGTCAACTCCCGCGCCTATTCCTTGCTCGGCACTTCCGAACGCA
CCGCGCTGACCGTGGCCCAGGTTTATCTGGATGTGCTGACCCGTCGCGAATTCGTGCGTCTGGCCGAAGAAAACCTCAAG
AGCCACCAGCGCATCTACGACCAGATCCAGCTGCGCACCCAGCGCGGCGTCGGCAGCGGTGCCGACCTCGATCAGGCCGA
AGCGCGGATGGCCCAGGCCCGCAACAACCTGATCACCGAGCAGACCAACCTCGCCGACTCGGAAACCAACTTCCTCAGCG
CCGTCGGCCAGATGCCCGATCAACTGGAGCGTCCGGCGCCGTTCATGGCGATGATGCCGGCCAACCTGAATGAAGCGCGC
CAGCAGATGCTGGAAAACAGCCCGATCCTGCGTTCGGCCGAGTCCGACATCGCCGCGGCCGAGAAGCAATACGAGACTGC
CAAGTCGACCTTCTACCCGCGCTTCGACGCCGAGCTGGGCCGCACCGCCGACAACGATCTCGACGGCCAGAACGGTCACA
ACAACGAATGGCAGGCCATGCTGCGCATGCGCTTCAACCTGTATTCGGGCGGCAGCAACAAGGCGGACCTGGAGTCCAAG
TCCTACCTGTCGAACCAGGCGCTGGACATCCGCAACAACGCCTTGCGCCAATTGAATGAAGAACTGGGCCTGGCCTGGAA
CGCCCTGAACAACGCCAACGCCCAAGTGCCGATCGCTCAGCAGTACGTTGATCACAGCACCTCGGTGCGCACCGCTTACC
AGCGTCAGTTCAGCCTCGGCGAACGCACCCTGCTGGATTTGCTCGACAGTGAAAACGAGCTGTTCACCGCTTCGCGCCGT
CTGGCCGAGATCAAAAACATTCAGTTATTTACTCAGTATCGAATCAAGGCGACCATGGGCGAGTTACTCAAGAGCCAGGG
AGTGGTCGCACCCTTGGCATCCGTTGTGCAGAACGACGTGAAGCCCAAGGTCCAGCTGCCTGGGATGAATTGA

Upstream 100 bases:

>100_bases
TTTTAAACTTTCCGACATACGGTCATTCCGGTTGCCATCTTCCGACGCAGCTCACTAATTTGCTGTGATTCAAGACAAGA
AGTTCTGGGAAATCTTTACC

Downstream 100 bases:

>100_bases
GTTGTCCCTTTTCAACTGCTAAAGAGTGTCGAGCGTGGAATCAGAAGTCAGTCGAGTTCATCTCAGTCATGATCCACGCG
CGTTGCACGACGATCCGTTA

Product: Type I secretion outer membrane protein, TolC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MRSHLFKALPFALAASFVQAQSLPEAMQQALDVHPEIQAGVNSRLAADYQLKAAKGGYLPKVDLLGGYGREGTDSVTTRA
NGGGNHWETLNRSESSLRLSQMVFDGFATSSEVGRQQATVNSRAYSLLGTSERTALTVAQVYLDVLTRREFVRLAEENLK
SHQRIYDQIQLRTQRGVGSGADLDQAEARMAQARNNLITEQTNLADSETNFLSAVGQMPDQLERPAPFMAMMPANLNEAR
QQMLENSPILRSAESDIAAAEKQYETAKSTFYPRFDAELGRTADNDLDGQNGHNNEWQAMLRMRFNLYSGGSNKADLESK
SYLSNQALDIRNNALRQLNEELGLAWNALNNANAQVPIAQQYVDHSTSVRTAYQRQFSLGERTLLDLLDSENELFTASRR
LAEIKNIQLFTQYRIKATMGELLKSQGVVAPLASVVQNDVKPKVQLPGMN

Sequences:

>Translated_450_residues
MRSHLFKALPFALAASFVQAQSLPEAMQQALDVHPEIQAGVNSRLAADYQLKAAKGGYLPKVDLLGGYGREGTDSVTTRA
NGGGNHWETLNRSESSLRLSQMVFDGFATSSEVGRQQATVNSRAYSLLGTSERTALTVAQVYLDVLTRREFVRLAEENLK
SHQRIYDQIQLRTQRGVGSGADLDQAEARMAQARNNLITEQTNLADSETNFLSAVGQMPDQLERPAPFMAMMPANLNEAR
QQMLENSPILRSAESDIAAAEKQYETAKSTFYPRFDAELGRTADNDLDGQNGHNNEWQAMLRMRFNLYSGGSNKADLESK
SYLSNQALDIRNNALRQLNEELGLAWNALNNANAQVPIAQQYVDHSTSVRTAYQRQFSLGERTLLDLLDSENELFTASRR
LAEIKNIQLFTQYRIKATMGELLKSQGVVAPLASVVQNDVKPKVQLPGMN
>Mature_450_residues
MRSHLFKALPFALAASFVQAQSLPEAMQQALDVHPEIQAGVNSRLAADYQLKAAKGGYLPKVDLLGGYGREGTDSVTTRA
NGGGNHWETLNRSESSLRLSQMVFDGFATSSEVGRQQATVNSRAYSLLGTSERTALTVAQVYLDVLTRREFVRLAEENLK
SHQRIYDQIQLRTQRGVGSGADLDQAEARMAQARNNLITEQTNLADSETNFLSAVGQMPDQLERPAPFMAMMPANLNEAR
QQMLENSPILRSAESDIAAAEKQYETAKSTFYPRFDAELGRTADNDLDGQNGHNNEWQAMLRMRFNLYSGGSNKADLESK
SYLSNQALDIRNNALRQLNEELGLAWNALNNANAQVPIAQQYVDHSTSVRTAYQRQFSLGERTLLDLLDSENELFTASRR
LAEIKNIQLFTQYRIKATMGELLKSQGVVAPLASVVQNDVKPKVQLPGMN

Specific function: Involved in the efflux of toxic and relatively hydrophobic compounds. Influences survival inside the host [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=433, Percent_Identity=24.0184757505774, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 49911; Mature: 49911

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHLFKALPFALAASFVQAQSLPEAMQQALDVHPEIQAGVNSRLAADYQLKAAKGGYLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHCCCEEEEECCCCCCC
KVDLLGGYGREGTDSVTTRANGGGNHWETLNRSESSLRLSQMVFDGFATSSEVGRQQATV
CCHHCCCCCCCCCCCCEECCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
NSRAYSLLGTSERTALTVAQVYLDVLTRREFVRLAEENLKSHQRIYDQIQLRTQRGVGSG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ADLDQAEARMAQARNNLITEQTNLADSETNFLSAVGQMPDQLERPAPFMAMMPANLNEAR
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCEEEECCCCHHHHH
QQMLENSPILRSAESDIAAAEKQYETAKSTFYPRFDAELGRTADNDLDGQNGHNNEWQAM
HHHHHCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHHH
LRMRFNLYSGGSNKADLESKSYLSNQALDIRNNALRQLNEELGLAWNALNNANAQVPIAQ
HHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHH
QYVDHSTSVRTAYQRQFSLGERTLLDLLDSENELFTASRRLAEIKNIQLFTQYRIKATMG
HHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLKSQGVVAPLASVVQNDVKPKVQLPGMN
HHHHHCCCHHHHHHHHHHCCCCCEECCCCC
>Mature Secondary Structure
MRSHLFKALPFALAASFVQAQSLPEAMQQALDVHPEIQAGVNSRLAADYQLKAAKGGYLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHCCCEEEEECCCCCCC
KVDLLGGYGREGTDSVTTRANGGGNHWETLNRSESSLRLSQMVFDGFATSSEVGRQQATV
CCHHCCCCCCCCCCCCEECCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
NSRAYSLLGTSERTALTVAQVYLDVLTRREFVRLAEENLKSHQRIYDQIQLRTQRGVGSG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ADLDQAEARMAQARNNLITEQTNLADSETNFLSAVGQMPDQLERPAPFMAMMPANLNEAR
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCEEEECCCCHHHHH
QQMLENSPILRSAESDIAAAEKQYETAKSTFYPRFDAELGRTADNDLDGQNGHNNEWQAM
HHHHHCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHHH
LRMRFNLYSGGSNKADLESKSYLSNQALDIRNNALRQLNEELGLAWNALNNANAQVPIAQ
HHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHH
QYVDHSTSVRTAYQRQFSLGERTLLDLLDSENELFTASRRLAEIKNIQLFTQYRIKATMG
HHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLKSQGVVAPLASVVQNDVKPKVQLPGMN
HHHHHCCCHHHHHHHHHHCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]