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The map label for this gene is dctB1 [H]

Identifier: 76818694

GI number: 76818694

Start: 1908805

End: 1910736

Strand: Direct

Name: dctB1 [H]

Synonym: BURPS1710b_A1572

Alternate gene names: 76818694

Gene position: 1908805-1910736 (Clockwise)

Preceding gene: 76819268

Following gene: 76819086

Centisome position: 59.99

GC content: 67.13

Gene sequence:

>1932_bases
ATGAGGCTGCGCGGCATCCGGCGGCTGCACCGGCCGGCGGCGGTGCTCGCCGTGATCGCGTGCTGCGTGGCGACGGCCTG
GCTCGGCTATTCGGTCGCGCTGCGCTACTACTTCCGCGCCCACATGAACGAGGTGGCGCAGCGCTCGTCGCTGTACGCGC
TGACGCTCGAATCGCAACTCGCGCGTTACGAATCGATTCCCCGCATCGCCGCGCTCGAGCCGGTGCTGTCGCGCCTCTTG
AACGATCCGGGCGAGCGCGCGCTGCGCGACGAGGCGAATGCGTATCTCAACGCGGTGCAGAAGAACGCCGAGCTGTCCGC
CGCGTATGTGATGAACGCTCGCGGCGAGACGCTCGCCGCGAGCAACAGCAATGAGCCGGGCAGCTTCGTCGGCTCGAACT
ACGCGTTTCGACCATACTTCGCCGACGCGATGAAGCGCGGATTCGGCCGCTTCTATGGCGTCGGCAATACCACCGGGCAG
GCCGGCTACTTTCTGGCCGTGCCGATCCGTAATCCGGGCCAGCCCGCGCGCGCGCCCATCGGCGTCGTCGCGATCAAGGC
GTCGCTCGATCGATACGAAGCCGCGTTGACGAAGAGCGGGGATGTCGTGTTGCTCGTCGACCGGGACGGCGTGGCGTTTC
TGTCGTCCGTCGCAAGCTGGCGCTATCGCACGCTGACGCCGATTCCCGCCGCGACGCTTCGCAAGCTCGCCGCGACGAGG
CAGTACGGCGACGCCGCGCTGGAGCCGTTGTCGGACACGCCGCCCGCGCCCGCCGGAGCGGGCCGTTCGTCGACGCAGGC
CGACTCCGCGCCGACTCCCGAATCGCTCCATCTGTCTTTATCCGGCGGGCGGCCCGCGTGGTATCACGTCGTCTATCGTG
CGGCCGGCCCGCTCGGCTGGAGGGTCGCGGTCCTCGTCGATTCCACCGACGACGAGCGCCGGGCGCTGTTCGCCTCCGGC
GGCGTGGCGGCGGCCACCGCTCTCGTATTCGCGCTCATCATGGTCGCATGGCTTCGCCATAGCCGCGAAAAGGAACGGCA
GCGCGCGAGAACGGCGCTTCTGGCGGCGCAGCGGGATCTGGAGCGCCGGATCGCCGAGCGGACCGCCGAGCTGACCGCTG
CGAACGCGGCGCTCGAAGAGAAGGTCGATGCGCTCGACGCCGCGCGCCGCATACTGCGCGACACGCGGGACACGGCGATA
CAGGCCGGCAAGCTCGCGGCGCTCGGGCAAATGGCGGCGGGCATCACCCACGAGCTGAATCAGCCGCTGGCCGCGATCAT
GACGCTATCGAGCAATGCCGTGCGCATGGCTGCCCTCGGCCGTTCGGCCGATCTCACGCGCAACCTGGAGCTCGTCAACG
ATCTGGCGGGGCGAATGGGCAAGATCGTCGCTCACATGAAAGGGTTCGCCCGCCACGAATCGGTCAGCCGGGAAGCCGTT
TCGATATCCGAAGCATTGCAGCAGGCGCTGACGTTGATCGAGGCGCATCGAAAGGCCGCGAAAGTATCCGTTCGCGTCGA
GCCGGTGCCTGGGCAAGGCATCGTGCTGGCCAGTTCGATCCGCATCGAGCAGCTTCTCGTGAATTTGCTGACCAACGCGA
TCGACGCGAGCGCCGCGGGTATGGACAATCGGCAGGTCGTGGTGACGACGGACGTGGCGGGCGATATCGTTCGCATCAGC
GTGGCGGACAGCGGCAAGGGCATTCCCGCCGACGTCATGCCACGGCTTTTCGAACCCTTCTTCACGACGAAGCAAACGGG
CAAGGGCCTGGGGCTGGGGCTCGCGATATCGCAGGCGATCGTCGACGAATTCGGCGGGCGGCTGCACGCGAGAAACGGCA
GCGGTGTCGAGCCCGAGTTGGGCGGCGCCGTTTTCATCGTCGAATTGCACCGCGTATCGAGAAAGTTTTCTTCCCATGAT
GAACGCAGATAA

Upstream 100 bases:

>100_bases
TACGTATGCATGCGGGATACCGGGAAGCACTCGCTGATCAAGGATTGATGGCGCCGGCCGCCACCGTGCCGACGGCGCCC
GCGCACGAGGATGCCGCGCG

Downstream 100 bases:

>100_bases
CGCTTATGGCCGCGAGGCCGTCTATGTGATCGAGGACGACGCGGCCGTGCGGTTGGGATGTTCGCAGGCGCTCGCGCTCG
AAGGCATCGGCGTGCGGGAG

Product: C4-dicarboxylate transport sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MRLRGIRRLHRPAAVLAVIACCVATAWLGYSVALRYYFRAHMNEVAQRSSLYALTLESQLARYESIPRIAALEPVLSRLL
NDPGERALRDEANAYLNAVQKNAELSAAYVMNARGETLAASNSNEPGSFVGSNYAFRPYFADAMKRGFGRFYGVGNTTGQ
AGYFLAVPIRNPGQPARAPIGVVAIKASLDRYEAALTKSGDVVLLVDRDGVAFLSSVASWRYRTLTPIPAATLRKLAATR
QYGDAALEPLSDTPPAPAGAGRSSTQADSAPTPESLHLSLSGGRPAWYHVVYRAAGPLGWRVAVLVDSTDDERRALFASG
GVAAATALVFALIMVAWLRHSREKERQRARTALLAAQRDLERRIAERTAELTAANAALEEKVDALDAARRILRDTRDTAI
QAGKLAALGQMAAGITHELNQPLAAIMTLSSNAVRMAALGRSADLTRNLELVNDLAGRMGKIVAHMKGFARHESVSREAV
SISEALQQALTLIEAHRKAAKVSVRVEPVPGQGIVLASSIRIEQLLVNLLTNAIDASAAGMDNRQVVVTTDVAGDIVRIS
VADSGKGIPADVMPRLFEPFFTTKQTGKGLGLGLAISQAIVDEFGGRLHARNGSGVEPELGGAVFIVELHRVSRKFSSHD
ERR

Sequences:

>Translated_643_residues
MRLRGIRRLHRPAAVLAVIACCVATAWLGYSVALRYYFRAHMNEVAQRSSLYALTLESQLARYESIPRIAALEPVLSRLL
NDPGERALRDEANAYLNAVQKNAELSAAYVMNARGETLAASNSNEPGSFVGSNYAFRPYFADAMKRGFGRFYGVGNTTGQ
AGYFLAVPIRNPGQPARAPIGVVAIKASLDRYEAALTKSGDVVLLVDRDGVAFLSSVASWRYRTLTPIPAATLRKLAATR
QYGDAALEPLSDTPPAPAGAGRSSTQADSAPTPESLHLSLSGGRPAWYHVVYRAAGPLGWRVAVLVDSTDDERRALFASG
GVAAATALVFALIMVAWLRHSREKERQRARTALLAAQRDLERRIAERTAELTAANAALEEKVDALDAARRILRDTRDTAI
QAGKLAALGQMAAGITHELNQPLAAIMTLSSNAVRMAALGRSADLTRNLELVNDLAGRMGKIVAHMKGFARHESVSREAV
SISEALQQALTLIEAHRKAAKVSVRVEPVPGQGIVLASSIRIEQLLVNLLTNAIDASAAGMDNRQVVVTTDVAGDIVRIS
VADSGKGIPADVMPRLFEPFFTTKQTGKGLGLGLAISQAIVDEFGGRLHARNGSGVEPELGGAVFIVELHRVSRKFSSHD
ERR
>Mature_643_residues
MRLRGIRRLHRPAAVLAVIACCVATAWLGYSVALRYYFRAHMNEVAQRSSLYALTLESQLARYESIPRIAALEPVLSRLL
NDPGERALRDEANAYLNAVQKNAELSAAYVMNARGETLAASNSNEPGSFVGSNYAFRPYFADAMKRGFGRFYGVGNTTGQ
AGYFLAVPIRNPGQPARAPIGVVAIKASLDRYEAALTKSGDVVLLVDRDGVAFLSSVASWRYRTLTPIPAATLRKLAATR
QYGDAALEPLSDTPPAPAGAGRSSTQADSAPTPESLHLSLSGGRPAWYHVVYRAAGPLGWRVAVLVDSTDDERRALFASG
GVAAATALVFALIMVAWLRHSREKERQRARTALLAAQRDLERRIAERTAELTAANAALEEKVDALDAARRILRDTRDTAI
QAGKLAALGQMAAGITHELNQPLAAIMTLSSNAVRMAALGRSADLTRNLELVNDLAGRMGKIVAHMKGFARHESVSREAV
SISEALQQALTLIEAHRKAAKVSVRVEPVPGQGIVLASSIRIEQLLVNLLTNAIDASAAGMDNRQVVVTTDVAGDIVRIS
VADSGKGIPADVMPRLFEPFFTTKQTGKGLGLGLAISQAIVDEFGGRLHARNGSGVEPELGGAVFIVELHRVSRKFSSHD
ERR

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=32.034632034632, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=28, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=216, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=26.6375545851528, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=29.7413793103448, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69061; Mature: 69061

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRGIRRLHRPAAVLAVIACCVATAWLGYSVALRYYFRAHMNEVAQRSSLYALTLESQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHH
ARYESIPRIAALEPVLSRLLNDPGERALRDEANAYLNAVQKNAELSAAYVMNARGETLAA
HHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEC
SNSNEPGSFVGSNYAFRPYFADAMKRGFGRFYGVGNTTGQAGYFLAVPIRNPGQPARAPI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCCCCCCCCE
GVVAIKASLDRYEAALTKSGDVVLLVDRDGVAFLSSVASWRYRTLTPIPAATLRKLAATR
EEEEEEHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHH
QYGDAALEPLSDTPPAPAGAGRSSTQADSAPTPESLHLSLSGGRPAWYHVVYRAAGPLGW
HCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCE
RVAVLVDSTDDERRALFASGGVAAATALVFALIMVAWLRHSREKERQRARTALLAAQRDL
EEEEEEECCCCHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERRIAERTAELTAANAALEEKVDALDAARRILRDTRDTAIQAGKLAALGQMAAGITHELN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QPLAAIMTLSSNAVRMAALGRSADLTRNLELVNDLAGRMGKIVAHMKGFARHESVSREAV
CHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SISEALQQALTLIEAHRKAAKVSVRVEPVPGQGIVLASSIRIEQLLVNLLTNAIDASAAG
HHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCC
MDNRQVVVTTDVAGDIVRISVADSGKGIPADVMPRLFEPFFTTKQTGKGLGLGLAISQAI
CCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VDEFGGRLHARNGSGVEPELGGAVFIVELHRVSRKFSSHDERR
HHHHCCEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRLRGIRRLHRPAAVLAVIACCVATAWLGYSVALRYYFRAHMNEVAQRSSLYALTLESQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHH
ARYESIPRIAALEPVLSRLLNDPGERALRDEANAYLNAVQKNAELSAAYVMNARGETLAA
HHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEC
SNSNEPGSFVGSNYAFRPYFADAMKRGFGRFYGVGNTTGQAGYFLAVPIRNPGQPARAPI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCCCCCCCCE
GVVAIKASLDRYEAALTKSGDVVLLVDRDGVAFLSSVASWRYRTLTPIPAATLRKLAATR
EEEEEEHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHH
QYGDAALEPLSDTPPAPAGAGRSSTQADSAPTPESLHLSLSGGRPAWYHVVYRAAGPLGW
HCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCE
RVAVLVDSTDDERRALFASGGVAAATALVFALIMVAWLRHSREKERQRARTALLAAQRDL
EEEEEEECCCCHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERRIAERTAELTAANAALEEKVDALDAARRILRDTRDTAIQAGKLAALGQMAAGITHELN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QPLAAIMTLSSNAVRMAALGRSADLTRNLELVNDLAGRMGKIVAHMKGFARHESVSREAV
CHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SISEALQQALTLIEAHRKAAKVSVRVEPVPGQGIVLASSIRIEQLLVNLLTNAIDASAAG
HHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCC
MDNRQVVVTTDVAGDIVRISVADSGKGIPADVMPRLFEPFFTTKQTGKGLGLGLAISQAI
CCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VDEFGGRLHARNGSGVEPELGGAVFIVELHRVSRKFSSHDERR
HHHHCCEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]