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The map label for this gene is dctD [H]

Identifier: 76819086

GI number: 76819086

Start: 1910648

End: 1912066

Strand: Direct

Name: dctD [H]

Synonym: BURPS1710b_A1573

Alternate gene names: 76819086

Gene position: 1910648-1912066 (Clockwise)

Preceding gene: 76818694

Following gene: 76817692

Centisome position: 60.05

GC content: 66.38

Gene sequence:

>1419_bases
GTGTCGAGCCCGAGTTGGGCGGCGCCGTTTTCATCGTCGAATTGCACCGCGTATCGAGAAAGTTTTCTTCCCATGATGAA
CGCAGATAACGCTTATGGCCGCGAGGCCGTCTATGTGATCGAGGACGACGCGGCCGTGCGGTTGGGATGTTCGCAGGCGC
TCGCGCTCGAAGGCATCGGCGTGCGGGAGTTCGAGGACGCCGAGAGCGCCCTCGCCGCGCTCAAGCGCGACCCGCCTGCG
GCGATCGTCAGTGACGTCAGGCTGCCCGGCATGGGCGGCCTCGCGCTGCTCGACAGCATGAAGGCCCACCCCCGGGACGC
CGACATACCGGTCATCCTGATGACGGGGCATGGCGACGTGGCGATGGCCGTGGGGGCGATGCGCTGCGGCGCGTACGATT
TCATCGAGAAGCCGTTTCATTCCGATCGGCTCGTCGACACGGTCCGCCGCGCGTTGGAGCACCGCAAGCTCGTGATCGAG
AATCGCAGTCTTCGCGCGCAACTGAGCGGCGAGCGGCCGTTGCTCGGGAGCGCGCCCGCGATGCAGCGCGTCCATGCGCT
CATCGACGCTATCGGCCCCACCAGCGCCGATGTCCTGATCATCGGCGAGACCGGGACGGGAAAGGAGGTGCTGGCGCGGG
CGCTGCACGCGGCGAGCCGCCGCACCGGGCCGTTCGTGGCGCTCAATTGCGCCGCGCTGCCCGAGGCCGTGTTCGAGAGC
GAGATCTTCGGGCATGAGCCCGGGGCTTTCACCGGCGCTCAGCAGCGGCGCATCGGCAAGTTCGAATACGCAAGCGGCGG
CACGCTGTTCCTCGACGAGCTCGAGTCGATGCCTTTGTCGCTTCAGGCCAAGCTCTTGCGCGCGCTTCAGGAGCGCAGCA
TCGAGCGGCTCGGCAGCAATGTCTCCGTCGCCGTCGACGTGCGGGTGATCGCCGCGGTCAAGCAGGACCTGAAACAGCTC
GCCGCCGACGGCCTGTTCCGGTCCGATCTGTATTTCCGGCTGAACGTGGCGTCGATCGAGCTGCCGCCGTTGCGCCGGCG
CACGGACGATATCCCGGAGCTCTTCAGTCATTTCCTCCGCGCCGCCGCCGTCAGGTTCGAAAAGCCTGAACCGGTCTGGA
CGCAGGAAGACATGATGCGTTGGCAGCTTTACGACTGGCCGGGCAACGTGCGCGAGCTGAAAAACACGGCGGAGCGGTTT
TGCCTCGGTCTCGAAGACGGCTTGCCGCGCTCGCCGGCCGGATTCGATTCGCTCGCGTCGCGTATGGTCAGCGCCGAGCG
CGCGTATATCGAGGAAGCGCTTCGCAACGCGGGCGGGCAGGTGGCCAAGGCGGCCGAGTTGCTCGGGCTGCCGCGTAAAA
CGCTATACGACAAGATCACGCGGCATGGCATCGATATGACGGCGTTTCGCTGCACGTGA

Upstream 100 bases:

>100_bases
ACGACGAAGCAAACGGGCAAGGGCCTGGGGCTGGGGCTCGCGATATCGCAGGCGATCGTCGACGAATTCGGCGGGCGGCT
GCACGCGAGAAACGGCAGCG

Downstream 100 bases:

>100_bases
CGCGTTTCGCGACGCGCGTCGATGGGGCGGGCGCGAAACCCGTTCGCCGCGATGCGGCGGACGGGGTATGGCCGAGCGCC
GTCCGTCGCGGCGAGAGTTG

Product: C4-dicarboxylate transport transcriptional response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSSPSWAAPFSSSNCTAYRESFLPMMNADNAYGREAVYVIEDDAAVRLGCSQALALEGIGVREFEDAESALAALKRDPPA
AIVSDVRLPGMGGLALLDSMKAHPRDADIPVILMTGHGDVAMAVGAMRCGAYDFIEKPFHSDRLVDTVRRALEHRKLVIE
NRSLRAQLSGERPLLGSAPAMQRVHALIDAIGPTSADVLIIGETGTGKEVLARALHAASRRTGPFVALNCAALPEAVFES
EIFGHEPGAFTGAQQRRIGKFEYASGGTLFLDELESMPLSLQAKLLRALQERSIERLGSNVSVAVDVRVIAAVKQDLKQL
AADGLFRSDLYFRLNVASIELPPLRRRTDDIPELFSHFLRAAAVRFEKPEPVWTQEDMMRWQLYDWPGNVRELKNTAERF
CLGLEDGLPRSPAGFDSLASRMVSAERAYIEEALRNAGGQVAKAAELLGLPRKTLYDKITRHGIDMTAFRCT

Sequences:

>Translated_472_residues
MSSPSWAAPFSSSNCTAYRESFLPMMNADNAYGREAVYVIEDDAAVRLGCSQALALEGIGVREFEDAESALAALKRDPPA
AIVSDVRLPGMGGLALLDSMKAHPRDADIPVILMTGHGDVAMAVGAMRCGAYDFIEKPFHSDRLVDTVRRALEHRKLVIE
NRSLRAQLSGERPLLGSAPAMQRVHALIDAIGPTSADVLIIGETGTGKEVLARALHAASRRTGPFVALNCAALPEAVFES
EIFGHEPGAFTGAQQRRIGKFEYASGGTLFLDELESMPLSLQAKLLRALQERSIERLGSNVSVAVDVRVIAAVKQDLKQL
AADGLFRSDLYFRLNVASIELPPLRRRTDDIPELFSHFLRAAAVRFEKPEPVWTQEDMMRWQLYDWPGNVRELKNTAERF
CLGLEDGLPRSPAGFDSLASRMVSAERAYIEEALRNAGGQVAKAAELLGLPRKTLYDKITRHGIDMTAFRCT
>Mature_471_residues
SSPSWAAPFSSSNCTAYRESFLPMMNADNAYGREAVYVIEDDAAVRLGCSQALALEGIGVREFEDAESALAALKRDPPAA
IVSDVRLPGMGGLALLDSMKAHPRDADIPVILMTGHGDVAMAVGAMRCGAYDFIEKPFHSDRLVDTVRRALEHRKLVIEN
RSLRAQLSGERPLLGSAPAMQRVHALIDAIGPTSADVLIIGETGTGKEVLARALHAASRRTGPFVALNCAALPEAVFESE
IFGHEPGAFTGAQQRRIGKFEYASGGTLFLDELESMPLSLQAKLLRALQERSIERLGSNVSVAVDVRVIAAVKQDLKQLA
ADGLFRSDLYFRLNVASIELPPLRRRTDDIPELFSHFLRAAAVRFEKPEPVWTQEDMMRWQLYDWPGNVRELKNTAERFC
LGLEDGLPRSPAGFDSLASRMVSAERAYIEEALRNAGGQVAKAAELLGLPRKTLYDKITRHGIDMTAFRCT

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=40.1766004415011, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1790299, Length=472, Percent_Identity=40.6779661016949, Blast_Score=308, Evalue=7e-85,
Organism=Escherichia coli, GI1790437, Length=442, Percent_Identity=41.8552036199095, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1788905, Length=451, Percent_Identity=37.2505543237251, Blast_Score=279, Evalue=3e-76,
Organism=Escherichia coli, GI87082117, Length=337, Percent_Identity=43.9169139465875, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1789087, Length=338, Percent_Identity=44.3786982248521, Blast_Score=238, Evalue=6e-64,
Organism=Escherichia coli, GI1789233, Length=227, Percent_Identity=47.136563876652, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1786524, Length=437, Percent_Identity=34.5537757437071, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87082152, Length=227, Percent_Identity=47.5770925110132, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI87081872, Length=228, Percent_Identity=46.0526315789474, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787583, Length=313, Percent_Identity=36.4217252396166, Blast_Score=175, Evalue=7e-45,
Organism=Escherichia coli, GI87081858, Length=294, Percent_Identity=33.3333333333333, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789828, Length=238, Percent_Identity=37.8151260504202, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1786599, Length=170, Percent_Identity=28.8235294117647, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51662; Mature: 51531

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4 ; PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPSWAAPFSSSNCTAYRESFLPMMNADNAYGREAVYVIEDDAAVRLGCSQALALEGIG
CCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEECCCHHHHHCCCC
VREFEDAESALAALKRDPPAAIVSDVRLPGMGGLALLDSMKAHPRDADIPVILMTGHGDV
CCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCH
AMAVGAMRCGAYDFIEKPFHSDRLVDTVRRALEHRKLVIENRSLRAQLSGERPLLGSAPA
HHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCCCCHH
MQRVHALIDAIGPTSADVLIIGETGTGKEVLARALHAASRRTGPFVALNCAALPEAVFES
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
EIFGHEPGAFTGAQQRRIGKFEYASGGTLFLDELESMPLSLQAKLLRALQERSIERLGSN
HHCCCCCCCCCCHHHHHCCCEEECCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
VSVAVDVRVIAAVKQDLKQLAADGLFRSDLYFRLNVASIELPPLRRRTDDIPELFSHFLR
CEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
AAAVRFEKPEPVWTQEDMMRWQLYDWPGNVRELKNTAERFCLGLEDGLPRSPAGFDSLAS
HHHHHCCCCCCCCCHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
RMVSAERAYIEEALRNAGGQVAKAAELLGLPRKTLYDKITRHGIDMTAFRCT
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure 
SSPSWAAPFSSSNCTAYRESFLPMMNADNAYGREAVYVIEDDAAVRLGCSQALALEGIG
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEECCCHHHHHCCCC
VREFEDAESALAALKRDPPAAIVSDVRLPGMGGLALLDSMKAHPRDADIPVILMTGHGDV
CCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCH
AMAVGAMRCGAYDFIEKPFHSDRLVDTVRRALEHRKLVIENRSLRAQLSGERPLLGSAPA
HHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCCCCHH
MQRVHALIDAIGPTSADVLIIGETGTGKEVLARALHAASRRTGPFVALNCAALPEAVFES
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
EIFGHEPGAFTGAQQRRIGKFEYASGGTLFLDELESMPLSLQAKLLRALQERSIERLGSN
HHCCCCCCCCCCHHHHHCCCEEECCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
VSVAVDVRVIAAVKQDLKQLAADGLFRSDLYFRLNVASIELPPLRRRTDDIPELFSHFLR
CEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
AAAVRFEKPEPVWTQEDMMRWQLYDWPGNVRELKNTAERFCLGLEDGLPRSPAGFDSLAS
HHHHHCCCCCCCCCHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
RMVSAERAYIEEALRNAGGQVAKAAELLGLPRKTLYDKITRHGIDMTAFRCT
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]