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The map label for this gene is kgtP [H]

Identifier: 76819268

GI number: 76819268

Start: 1906848

End: 1908752

Strand: Direct

Name: kgtP [H]

Synonym: BURPS1710b_A1571

Alternate gene names: 76819268

Gene position: 1906848-1908752 (Clockwise)

Preceding gene: 76817253

Following gene: 76818694

Centisome position: 59.93

GC content: 61.89

Gene sequence:

>1905_bases
ATGTTTTCTCCCTTTATCCAGTCAAGCATGGGGGTCAATATAGCGGGTAATAAGAAATTTTCAAGAATATCGTGGGACCG
GACATCGAATTTTCGCCGGCGGGCGATGCGCATTGCACTTCGCGGGGGTCCATTTTCGGGATCGCGCGATGTTCGTGCAA
TGCTCGTCGTCGCGGCGCAATCGGATTGCGGGCAGCGCGCATTCAGGCAGGATGCCCGGTACACGTTTGCGGCCGGATAT
TGTTCTTGCCCCTCTGATCCTTCCGATTCCCGCAGCCCTTTTCGCGCGGCGGCGTTTTGGCCGGCATTGCGGCCGGCATT
GCAACCAGCCAGCGGGCGAAGCGCGACGCGGCGCCGTTGCGGTCATCCGCACACGCGAGGCCCGGAATTCCGGAGATCCG
CACAACGGATTGCGGCGTGTTTCGTCCGCTTTAAAAAAAGGCCATACAAACCAGAGGCTTATGAAGGGCTCGACAGATCG
GCTCGTTGGCACTGTTGTTGCAAGAGGATGGCACCGCATCGAGCGGCATTCGACAAAACACCAGGAGACGCCATGGAGCC
GACCTTTACCGAAACCGGCGCGCGGGCGAGCGAGCCCCACGCAACAACGCTTGCCGGCCGAGCCGCATCGTCCGGCGATA
AGCTGCAACGCCTGAAGTCGATCTTCTCCGCATCGGCGGGCAATCTGATCGAGTGGTACGACTGGTACGTGTATTCGGCC
TTTGCGCTGTACTTCGCGCATTCGTTTTTTCCGGCCGGCAACCAGACCGCGCAACTGCTCAACACGGCCGCCGTCTTCGC
GGTGGGCTTTCTGGCGCGCCCCGTCGGCGGCTGGCTGATGGGGATCTACGCGGATCGCTACGGCCGCCGTCCGGCCTTGC
TCGTATCGGTCGTGCTGATGTGCGTGGGCTCGCTCATCATCGCCCTCTGCCCGGGGTATGACGTGATCGGCACGGCCGCG
CCTGTCCTGCTCGTCGTCGCCCGCCTGCTGCAGGGCTTGAGCGTCGGGGGCGAATACGGCACGTCGGCGACCTATCTCAG
CGAAGTCGCGACCGCCCGCGATCGCGGCTTCTACTCCAGCTTTCAGTACGTCACGCTGGTTGCCGGCCAACTCGTCGCGT
TGGCGCTGCTGATCGTCCTGCAGCAATTCGTGCTGACGACACAGCAGCTCGAAAGCTGGGGGTGGAGAATTCCGTTCTTC
ATCGGCGCGGCGTGCGCGCTGGCCGCCATGCGCCTGCGCTCGTCGATGGAGGAAACGGGCGAATTCAAGCGGACCTTAAA
CGCCCGGGACAAGCGCGGCACGCTCGCGGAACTGAGCAAGCATCCGCGCGCGGTCCTGACCGTGGTCGGCCTGACGATGG
GCGGCACGATCGCGTTCTACACCTACTCGATCTACATGCAGAAATTCCTCGTGAACACCGTCGGCATGAGCAAACATGAT
GCGACCCTGGTATCCGCCGCGTCGCTCGCCCTGTTCGCGATCTTGCAGCCGATCGTCGGCTCGATCTCCGATCGCATCGG
CCGTCGCCCCGTGCTGATCGCGTTCGGCGTGCTCGGCACGTTGTTCACCGTGCCGATCATGACGGCCATCAGCCGGACTC
ATGACGTTTGGACCGCGTTCTTCCTCAACATGGCGGCGCTGGTGATCGTGTCGGGGTATACCTCGATCAACGCAGTCGTG
AAGGCGGAATTGTTCCCTGCGAAAATCCGTGCACTGGGCGTCGGCTTTCCGTATGCACTCACCGTGTCGATCTTCGGCGG
CACGGCGGAGTATCTGGCGCTCTGGCTCAAGCAGGCTGGCCACGAATCGCTGTTCTATTGGTACGTGACAGCCGCCATAT
TCTGTTCGTTGCTCGTCTACGTATGCATGCGGGATACCGGGAAGCACTCGCTGATCAAGGATTGA

Upstream 100 bases:

>100_bases
GCGAACTTCCTTCAAGACCGTCTCGAGTTCCGAGCGTCTCGCTTCTTCTGCCTGACGCAGGATCTCATCGGCTTTGGCTT
TCAATTCGAGATAAGTACTC

Downstream 100 bases:

>100_bases
TGGCGCCGGCCGCCACCGTGCCGACGGCGCCCGCGCACGAGGATGCCGCGCGATGAGGCTGCGCGGCATCCGGCGGCTGC
ACCGGCCGGCGGCGGTGCTC

Product: alpha-ketoglutarate permease

Products: Proton [Cytoplasm]; 2-oxoglutarate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MFSPFIQSSMGVNIAGNKKFSRISWDRTSNFRRRAMRIALRGGPFSGSRDVRAMLVVAAQSDCGQRAFRQDARYTFAAGY
CSCPSDPSDSRSPFRAAAFWPALRPALQPASGRSATRRRCGHPHTRGPEFRRSAQRIAACFVRFKKRPYKPEAYEGLDRS
ARWHCCCKRMAPHRAAFDKTPGDAMEPTFTETGARASEPHATTLAGRAASSGDKLQRLKSIFSASAGNLIEWYDWYVYSA
FALYFAHSFFPAGNQTAQLLNTAAVFAVGFLARPVGGWLMGIYADRYGRRPALLVSVVLMCVGSLIIALCPGYDVIGTAA
PVLLVVARLLQGLSVGGEYGTSATYLSEVATARDRGFYSSFQYVTLVAGQLVALALLIVLQQFVLTTQQLESWGWRIPFF
IGAACALAAMRLRSSMEETGEFKRTLNARDKRGTLAELSKHPRAVLTVVGLTMGGTIAFYTYSIYMQKFLVNTVGMSKHD
ATLVSAASLALFAILQPIVGSISDRIGRRPVLIAFGVLGTLFTVPIMTAISRTHDVWTAFFLNMAALVIVSGYTSINAVV
KAELFPAKIRALGVGFPYALTVSIFGGTAEYLALWLKQAGHESLFYWYVTAAIFCSLLVYVCMRDTGKHSLIKD

Sequences:

>Translated_634_residues
MFSPFIQSSMGVNIAGNKKFSRISWDRTSNFRRRAMRIALRGGPFSGSRDVRAMLVVAAQSDCGQRAFRQDARYTFAAGY
CSCPSDPSDSRSPFRAAAFWPALRPALQPASGRSATRRRCGHPHTRGPEFRRSAQRIAACFVRFKKRPYKPEAYEGLDRS
ARWHCCCKRMAPHRAAFDKTPGDAMEPTFTETGARASEPHATTLAGRAASSGDKLQRLKSIFSASAGNLIEWYDWYVYSA
FALYFAHSFFPAGNQTAQLLNTAAVFAVGFLARPVGGWLMGIYADRYGRRPALLVSVVLMCVGSLIIALCPGYDVIGTAA
PVLLVVARLLQGLSVGGEYGTSATYLSEVATARDRGFYSSFQYVTLVAGQLVALALLIVLQQFVLTTQQLESWGWRIPFF
IGAACALAAMRLRSSMEETGEFKRTLNARDKRGTLAELSKHPRAVLTVVGLTMGGTIAFYTYSIYMQKFLVNTVGMSKHD
ATLVSAASLALFAILQPIVGSISDRIGRRPVLIAFGVLGTLFTVPIMTAISRTHDVWTAFFLNMAALVIVSGYTSINAVV
KAELFPAKIRALGVGFPYALTVSIFGGTAEYLALWLKQAGHESLFYWYVTAAIFCSLLVYVCMRDTGKHSLIKD
>Mature_634_residues
MFSPFIQSSMGVNIAGNKKFSRISWDRTSNFRRRAMRIALRGGPFSGSRDVRAMLVVAAQSDCGQRAFRQDARYTFAAGY
CSCPSDPSDSRSPFRAAAFWPALRPALQPASGRSATRRRCGHPHTRGPEFRRSAQRIAACFVRFKKRPYKPEAYEGLDRS
ARWHCCCKRMAPHRAAFDKTPGDAMEPTFTETGARASEPHATTLAGRAASSGDKLQRLKSIFSASAGNLIEWYDWYVYSA
FALYFAHSFFPAGNQTAQLLNTAAVFAVGFLARPVGGWLMGIYADRYGRRPALLVSVVLMCVGSLIIALCPGYDVIGTAA
PVLLVVARLLQGLSVGGEYGTSATYLSEVATARDRGFYSSFQYVTLVAGQLVALALLIVLQQFVLTTQQLESWGWRIPFF
IGAACALAAMRLRSSMEETGEFKRTLNARDKRGTLAELSKHPRAVLTVVGLTMGGTIAFYTYSIYMQKFLVNTVGMSKHD
ATLVSAASLALFAILQPIVGSISDRIGRRPVLIAFGVLGTLFTVPIMTAISRTHDVWTAFFLNMAALVIVSGYTSINAVV
KAELFPAKIRALGVGFPYALTVSIFGGTAEYLALWLKQAGHESLFYWYVTAAIFCSLLVYVCMRDTGKHSLIKD

Specific function: Uptake of alpha-ketoglutarate across the boundary membrane with the concomitant import of a cation (symport system) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788942, Length=429, Percent_Identity=51.5151515151515, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1790550, Length=442, Percent_Identity=31.447963800905, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1788292, Length=410, Percent_Identity=30.2439024390244, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1789941, Length=426, Percent_Identity=29.5774647887324, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI87082231, Length=218, Percent_Identity=31.651376146789, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082404, Length=378, Percent_Identity=24.0740740740741, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 69472; Mature: 69472

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSPFIQSSMGVNIAGNKKFSRISWDRTSNFRRRAMRIALRGGPFSGSRDVRAMLVVAAQ
CCCCHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECC
SDCGQRAFRQDARYTFAAGYCSCPSDPSDSRSPFRAAAFWPALRPALQPASGRSATRRRC
CHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHC
GHPHTRGPEFRRSAQRIAACFVRFKKRPYKPEAYEGLDRSARWHCCCKRMAPHRAAFDKT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHCCCCHHHCCCC
PGDAMEPTFTETGARASEPHATTLAGRAASSGDKLQRLKSIFSASAGNLIEWYDWYVYSA
CCCCCCCCHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FALYFAHSFFPAGNQTAQLLNTAAVFAVGFLARPVGGWLMGIYADRYGRRPALLVSVVLM
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
CVGSLIIALCPGYDVIGTAAPVLLVVARLLQGLSVGGEYGTSATYLSEVATARDRGFYSS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHH
FQYVTLVAGQLVALALLIVLQQFVLTTQQLESWGWRIPFFIGAACALAAMRLRSSMEETG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EFKRTLNARDKRGTLAELSKHPRAVLTVVGLTMGGTIAFYTYSIYMQKFLVNTVGMSKHD
HHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCH
ATLVSAASLALFAILQPIVGSISDRIGRRPVLIAFGVLGTLFTVPIMTAISRTHDVWTAF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLNMAALVIVSGYTSINAVVKAELFPAKIRALGVGFPYALTVSIFGGTAEYLALWLKQAG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCC
HESLFYWYVTAAIFCSLLVYVCMRDTGKHSLIKD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFSPFIQSSMGVNIAGNKKFSRISWDRTSNFRRRAMRIALRGGPFSGSRDVRAMLVVAAQ
CCCCHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECC
SDCGQRAFRQDARYTFAAGYCSCPSDPSDSRSPFRAAAFWPALRPALQPASGRSATRRRC
CHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHC
GHPHTRGPEFRRSAQRIAACFVRFKKRPYKPEAYEGLDRSARWHCCCKRMAPHRAAFDKT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHCCCCHHHCCCC
PGDAMEPTFTETGARASEPHATTLAGRAASSGDKLQRLKSIFSASAGNLIEWYDWYVYSA
CCCCCCCCHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FALYFAHSFFPAGNQTAQLLNTAAVFAVGFLARPVGGWLMGIYADRYGRRPALLVSVVLM
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
CVGSLIIALCPGYDVIGTAAPVLLVVARLLQGLSVGGEYGTSATYLSEVATARDRGFYSS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHH
FQYVTLVAGQLVALALLIVLQQFVLTTQQLESWGWRIPFFIGAACALAAMRLRSSMEETG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EFKRTLNARDKRGTLAELSKHPRAVLTVVGLTMGGTIAFYTYSIYMQKFLVNTVGMSKHD
HHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCH
ATLVSAASLALFAILQPIVGSISDRIGRRPVLIAFGVLGTLFTVPIMTAISRTHDVWTAF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLNMAALVIVSGYTSINAVVKAELFPAKIRALGVGFPYALTVSIFGGTAEYLALWLKQAG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCC
HESLFYWYVTAAIFCSLLVYVCMRDTGKHSLIKD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 2-oxoglutarate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 2-oxoglutarate [Periplasm] = Proton [Cytoplasm] + 2-oxoglutarate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2118499; 9205837; 9278503; 1709493; 2190187; 2053984; 8419306 [H]