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The map label for this gene is dsbD [H]

Identifier: 75910027

GI number: 75910027

Start: 4759735

End: 4760475

Strand: Direct

Name: dsbD [H]

Synonym: Ava_3823

Alternate gene names: 75910027

Gene position: 4759735-4760475 (Clockwise)

Preceding gene: 75910022

Following gene: 75910028

Centisome position: 74.77

GC content: 44.67

Gene sequence:

>741_bases
ATGCTAGAGACTCTGCAAACCCAAATTTACCAACTAGAAAAATTTGCTAACACCCTTGTCTCTTACCAACTGACACACCT
GAGTTTGCTGAGTATTGGGATCATTTTTGCCGCAGGGTTACTCACTAGCCTCACACCCTGTATGCTGTCCATGTTGCCAA
TTACTATTGGCTACATCGGTGGTTATGAAGCCAAAAGTCGTTGGCAAGCAGCAGCCCAATCAACTTGGTTTGCCTTGGGA
TTGGCGACTACCCTAGCAGGACTAGGCGTGGTAGCTGCTTTGGTTGGCAAAGTCTACGGTCAGATAGGTATTGGTTTACC
GATTATTGTCAGTATCATTGCTATCTTGATGGGGCTAAACTTACTAGAAGCTTTACCTCTGCAACTTCCATCTTTTGGTG
ATACTAATTGGATTCCCCAAGACTTGCCTTCAGGGGTGCGTTCCTACGGTATTGGCTTAACTTTCGGCTTGGTCGCCTCC
CCTTGTAGTACTCCTGTGTTAGCCAGTCTACTAGGTTGGGTTGCCAACACACAAGATTTAATTTTAGGCGCTGTTTTGTT
GATTTCTTATACAGCAGGCTATGTAACTCCCTTGATTTTGGCGGGTACTTTCACAGCATCAATTAAAAAGTTGCTGGAAC
TGCGTCGCTGGTCTGGTTGGATAAATCCAGTTAGCGGTGCATTATTGGTAGGATTTGGCGTATTTTCTCTAATTTCTCGG
ATTCCTCTAGGCAGTTTTTAA

Upstream 100 bases:

>100_bases
TCGTATAAGCGCATCCTCAGTTCTGAAGTCACCCCAACGCCGCAGCCCAAAATAAGCTAAAATTCAAGCAGATTAAGCAT
TTCGCCCTCAGTAATCCCCC

Downstream 100 bases:

>100_bases
GCAATGACTACAGACAATTCAGCCCCCACAGCATCCCCTTGGTGGTCGCTACCAGGAAAATTTTTGCGACGAGAGTTTTT
ACCTGTACTGACAGATTTAC

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MLETLQTQIYQLEKFANTLVSYQLTHLSLLSIGIIFAAGLLTSLTPCMLSMLPITIGYIGGYEAKSRWQAAAQSTWFALG
LATTLAGLGVVAALVGKVYGQIGIGLPIIVSIIAILMGLNLLEALPLQLPSFGDTNWIPQDLPSGVRSYGIGLTFGLVAS
PCSTPVLASLLGWVANTQDLILGAVLLISYTAGYVTPLILAGTFTASIKKLLELRRWSGWINPVSGALLVGFGVFSLISR
IPLGSF

Sequences:

>Translated_246_residues
MLETLQTQIYQLEKFANTLVSYQLTHLSLLSIGIIFAAGLLTSLTPCMLSMLPITIGYIGGYEAKSRWQAAAQSTWFALG
LATTLAGLGVVAALVGKVYGQIGIGLPIIVSIIAILMGLNLLEALPLQLPSFGDTNWIPQDLPSGVRSYGIGLTFGLVAS
PCSTPVLASLLGWVANTQDLILGAVLLISYTAGYVTPLILAGTFTASIKKLLELRRWSGWINPVSGALLVGFGVFSLISR
IPLGSF
>Mature_246_residues
MLETLQTQIYQLEKFANTLVSYQLTHLSLLSIGIIFAAGLLTSLTPCMLSMLPITIGYIGGYEAKSRWQAAAQSTWFALG
LATTLAGLGVVAALVGKVYGQIGIGLPIIVSIIAILMGLNLLEALPLQLPSFGDTNWIPQDLPSGVRSYGIGLTFGLVAS
PCSTPVLASLLGWVANTQDLILGAVLLISYTAGYVTPLILAGTFTASIKKLLELRRWSGWINPVSGALLVGFGVFSLISR
IPLGSF

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 25998; Mature: 25998

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure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CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA