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The map label for this gene is phoB [H]

Identifier: 75908963

GI number: 75908963

Start: 3391972

End: 3392427

Strand: Direct

Name: phoB [H]

Synonym: Ava_2751

Alternate gene names: 75908963

Gene position: 3391972-3392427 (Clockwise)

Preceding gene: 75908955

Following gene: 75908964

Centisome position: 53.28

GC content: 37.72

Gene sequence:

>456_bases
ATGTATCTAACCAATTCATTCATAAGTGATAACAAGAAGCACTACTCTCAGCAGCCTTTAGTTTTGGCAGTTGAAGATCA
CGATGACAGTCTTTTGCTGATTAGTTATGCCCTTGAGTCAATTGGTTGTAGATTCATTTGCCAAAAAGACAGTTCTGCAA
CTGTATTGGTGGCAAAAGAGTATCAGCCTGATTTAATTATGTTAGATATTTTATTACCTGGTTTAAATGGGCTGGAGGTT
GTACGTCATCTGAAAGAAGAACCTCTGACTCAGGAAATCCCCGTAATCGCTGTGACAGCGTTAGCTACAAAGGAAGACCA
AAACAAGATTATGAAGGCAGGCTTTGATGAATACATCTGCAAACCATACATGATTGAAGACTTAGAAGCAGTTATACACA
GAATTTTGTGCGGTAAATTTTATCCACATTCAGCTTATCAACTATGTCAAGATTAG

Upstream 100 bases:

>100_bases
GCCAATATCAAAATTCAGCCTAATATATTCTTTACGTTATATTTTGTCTGTTTCCACGATATTCAACGATAAAATCCAAT
GGCATCTTCATGGAGAAGAA

Downstream 100 bases:

>100_bases
GGACAGGGGGCATGAGGAAGAATATCTTATCTCATGGCTCAGCACTCCTTTAACTAGCTATTTAAGTAGAACAAGGTAAA
TAATCAAACGTTTGTAGTGA

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MYLTNSFISDNKKHYSQQPLVLAVEDHDDSLLLISYALESIGCRFICQKDSSATVLVAKEYQPDLIMLDILLPGLNGLEV
VRHLKEEPLTQEIPVIAVTALATKEDQNKIMKAGFDEYICKPYMIEDLEAVIHRILCGKFYPHSAYQLCQD

Sequences:

>Translated_151_residues
MYLTNSFISDNKKHYSQQPLVLAVEDHDDSLLLISYALESIGCRFICQKDSSATVLVAKEYQPDLIMLDILLPGLNGLEV
VRHLKEEPLTQEIPVIAVTALATKEDQNKIMKAGFDEYICKPYMIEDLEAVIHRILCGKFYPHSAYQLCQD
>Mature_151_residues
MYLTNSFISDNKKHYSQQPLVLAVEDHDDSLLLISYALESIGCRFICQKDSSATVLVAKEYQPDLIMLDILLPGLNGLEV
VRHLKEEPLTQEIPVIAVTALATKEDQNKIMKAGFDEYICKPYMIEDLEAVIHRILCGKFYPHSAYQLCQD

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=35.2941176470588, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1786911, Length=110, Percent_Identity=34.5454545454545, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 17148; Mature: 17148

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLTNSFISDNKKHYSQQPLVLAVEDHDDSLLLISYALESIGCRFICQKDSSATVLVAKE
CCCCCCHHCCCHHHCCCCCEEEEEECCCCCEEHHHHHHHHCCEEEEEECCCCCEEEEEEC
YQPDLIMLDILLPGLNGLEVVRHLKEEPLTQEIPVIAVTALATKEDQNKIMKAGFDEYIC
CCCCEEEEEEHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHCCCHHHHC
KPYMIEDLEAVIHRILCGKFYPHSAYQLCQD
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
>Mature Secondary Structure
MYLTNSFISDNKKHYSQQPLVLAVEDHDDSLLLISYALESIGCRFICQKDSSATVLVAKE
CCCCCCHHCCCHHHCCCCCEEEEEECCCCCEEHHHHHHHHCCEEEEEECCCCCEEEEEEC
YQPDLIMLDILLPGLNGLEVVRHLKEEPLTQEIPVIAVTALATKEDQNKIMKAGFDEYIC
CCCCEEEEEEHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHCCCHHHHC
KPYMIEDLEAVIHRILCGKFYPHSAYQLCQD
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]