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The map label for this gene is pksL [H]

Identifier: 75908807

GI number: 75908807

Start: 3210892

End: 3214221

Strand: Direct

Name: pksL [H]

Synonym: Ava_2593

Alternate gene names: 75908807

Gene position: 3210892-3214221 (Clockwise)

Preceding gene: 75908806

Following gene: 75908808

Centisome position: 50.44

GC content: 43.84

Gene sequence:

>3330_bases
ATGTTTGCAGCAGAAAATAACAACACAGCAAAAATCGCCATTGTAGGTATGGATGCCTTCTTTGGTGAGTGCAATGGCTT
AGATGCTTTTGAACGCAGTATTTATGATGGTAAGCAGCATTTCATTACCCTACCGCCGAAAAGATGGTACGGTATTGACG
AGCAGAAAGACTTACTGCAAGAGTATGGTTTAACTGATGGTAAAGCCCCTGTAGGTGCTTATATCAAAGACTTTGATTTA
GACACTCTCGCTTATAAGATTCCTCCTAACGAAGTCGAAAAACTCAACCCTCAACAATTGCTACTGTTGACAGTGGCCGA
TCGCGCCCTGAAAGATGCGAAAATTCCTGAAGGTGGCAATGTAGCTGTGATTATTGCGGCTGAAGCCGAATTGTCTGTAC
ACAAGCTACAGCAACGGTGGGATTCATCTTGGCAAGTTAAAGATGGTTTGAATGCGGCGGAAATTACCTTACCATCAACC
CAAGTTTCCCAACTGGAAAGTATTGTTAAAGACAGTGTTCACCATCAGGTAGAAATTGGTGAGTATTTGAGCTACATCAC
CAATATCATGGCTAGTCGGATTTCCTCTTTGTGGAATTTCACCGGCCCTTCTTTCACCCTTACGGCTGTAGAAAGTTCGG
CTTTTAAGGCGGTGGAAGTTGCCCAAATGCTGTTGATGACTCAAGAAGTGGATGCAGTGGTTGTGGGTGCGGTAGATTTG
GCTGGCGGTGTGGAAAACGTATTATTACGTAGTCAAACCGCACCAATTAATACTGGCGCTAATACTCTCAGCTATGACCA
AAAAGCCAATGGTTGGACGGTGGGAGAAGGGGCGGGTGCTGTTGTTCTCAAGCGTCATCAGCAAGCGATAGAAAATGGCG
ATCGCATTTATGCTGTAATTGATGCTATTAGTATTGGGCAATCCCACACCAAAGTCTATGGGGGCAGTGTTAACCAAGCC
TGTCAGCAAGCCTTAAAGATGGCGGGTGTGCCACCTGAGCAAGTCAAGTATGTGGAGGTTTGCGCTAGTGGGATTCCCCA
GGAAGATGAGGCAGAAATCGCTGGTTTAGTTCAGGCTTATCCATCGGTGGGTGATGGTTTGCACTGTGCAATTGGCAGTG
TCAAAGCGAACATTGGTCATACTTTTGTGGCTTCGGGAATTGCCAGTTTAATTAAAACTGCTCTGTGTTTGTATTACAGA
TATATCCCGGCTACTCCTAACTGGTCTGGTGTGAAGACTCCCCAAGCATTTGAGGGTAGCCCCTTCTATGTAGTTACAGA
ATCTAGACCTTGGTTTCTCAGCAAGAACGCCTCCCGACGTATTGCGGCGATTAATGGTATGGGGTGTGATGGTAGTTATG
CCCATGTCATCTTGTCGGAAGAAACTAATCAAGCCGAACGCCCGAATCAGTATTTGGAACAGATGCCCTTTTTGCTGTTC
CCGGTGGCTGGTGATGACCGGACAAGCCTTTTAGAGGCTTTGGATAAGCTGCAAAAGAGTATTGCTGAGAGTGCTGATTT
TTCTCGTAGTGCTAGCCTGGCTTTTACTACTTTCCAGCAGCAATCACAAGCTAACTACGCGGTATCAATTACGGGGCGGA
ACAAAAAAGAACTCCTCCGAGAAATCGAATCGGCACGGAAAGGTATTAACACAGCTTTTGATAAGGGTACAGATTGGCAA
ACCCCTGTAGGTAGTTATTTCACAGCCCAACCCTTGGGTAAAAAGGGTGAAGTGGCTTACGTGTATCCGGCGGCGGTTAA
TTCTTATATAGGTATCGGGCGCAATCTTTTCCGCCTCTTTCCCAAACTCCACGATAATTCTTTTGTTAAGAGCCTCTACA
AACGGGCTGCGGATATTGAACGCTTAGTTTTCCCCAGAAGCTTAAGTAAGTTATCTACTAGGCAGTTAGAACAGCTAGAG
AAAAAACTCTTGAGCGATTCCCTAGCGATGTTTGAAGCAGAAATTTTCTGCACCAGATTGCTGACGACAATTATTCGGGA
TGATTTTCAAGTCCACCCCAAATATGTGTTTGGCTACAGCTTGGGTGAAACCAGTATGATGGTTGCTCAAGGGATTTGGA
GCAATTTTTCGGAAGTTAGTAACTCTTTTAACTCATCAACTTTATTTGGTGATAGGTTATCCGGGCCGAAAAATTCGGTG
CGTGAGTATTGGGGATTACCAAAAGCTGCTACGGCTTCAGGTGATAATTTATGGGGTAATTATGTGCTGATGGCTAGTCC
TGTCCAAGTGCGGGATGCTATCCGAAACGAACCCCGTGTTTATCTGACGCAAATTAATACACCGGAAGAGGTATTAATTG
CCGGTGACCCAGCAGCTTGTCAAAGGGTGATTAAAACCATTGGCTGTAATTCTTTCACAGCGCCCTTTGATCATGTAATT
CATTGTCAGGCCATGCGATCGGAGTATGATGAGTTTGTGCAATTAAATAGCTTACCAGTCCAAGATATTGCTGATATCAC
CTTCTACTCTGCGGCGGAGTATCAACCTATAAAACTGGAGACTGGAGTTGTGGCTAAAAGTCTGGCGACTGGGTTATCCC
AAGAACTGGATTTTCCCAAATTAGTAAACCGCATCTACGACGACGGGGCAAAAATCTTTATTGAGGCTGGCCCTGGTAGT
GTTTGTTCTCGTTGGATTGACAAAATTTTAGAAGACAAAGAACACATCACCGTTTCCCTCAATCGTCGAGGAATTGATGA
CCATACTTCTTTCGTGAAAGCTTTAGCTAAACTTGTCAGTCATCGGGTGAATGTGGATTTGTCACCACTGTACAGCCCAG
TGATTGAAACTAGCAACTTAAATAAAGTCACACTGCGGAAGATAACCGTCGGTGGTGACTCCATCAGTGGCAAAATCTTG
AGTCCAGAAAACCTCCAGCTATTTGCAGAAATTAGGGAGAAAAAGCAACAAAATATAGCACCCTCTGGTAATGCTTTAGG
TATTAATTCAACGTATTTATCTCATCAAAAAAGTCTACCAAAGCCAAAACCATTTTCCGCAGAAAATATCATTGAACACG
GTTTAAAGCCAGAAGAACCATTAAAATCGTCTGAGTTAACTGCAACTCAACCAGCCAAACCGTCAGATTTTCTCTCCAAT
ACCACCACCGATATCGAATTTGCCACCATCATCAATATGTTGGATTTAAATAAGGCTCAGTATCAAAAACTGAATGCGAA
TAATCTGCAAATAACGCAAAATCACACAGCCTTCTTAAAAGCCAGACAAGATTTTAGTCAGCAAATGAGCGAAATTATTC
AATTACAAATGGTTTGTGCCGAAGATTTATTGCAGGAAGACGGTAACTAG

Upstream 100 bases:

>100_bases
TATGTTTAGGTTTTATTGCACTGACGCACCTTACATCTACTCACTTCTGCCTCCTGCCTTTCTTCTATCAATTCAACCTT
GACAGGCTAATAGTAAAGTG

Downstream 100 bases:

>100_bases
TTTAGTAAGAGTTTTAGTTTGAGGGGGATTTGGTAATAGATAATTGGTCATTCTCTACCCCCCATTACCTATTACCCATT
ACCCATTACCAATAGGTAGT

Product: beta-ketoacyl synthase

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: PKS [H]

Number of amino acids: Translated: 1109; Mature: 1109

Protein sequence:

>1109_residues
MFAAENNNTAKIAIVGMDAFFGECNGLDAFERSIYDGKQHFITLPPKRWYGIDEQKDLLQEYGLTDGKAPVGAYIKDFDL
DTLAYKIPPNEVEKLNPQQLLLLTVADRALKDAKIPEGGNVAVIIAAEAELSVHKLQQRWDSSWQVKDGLNAAEITLPST
QVSQLESIVKDSVHHQVEIGEYLSYITNIMASRISSLWNFTGPSFTLTAVESSAFKAVEVAQMLLMTQEVDAVVVGAVDL
AGGVENVLLRSQTAPINTGANTLSYDQKANGWTVGEGAGAVVLKRHQQAIENGDRIYAVIDAISIGQSHTKVYGGSVNQA
CQQALKMAGVPPEQVKYVEVCASGIPQEDEAEIAGLVQAYPSVGDGLHCAIGSVKANIGHTFVASGIASLIKTALCLYYR
YIPATPNWSGVKTPQAFEGSPFYVVTESRPWFLSKNASRRIAAINGMGCDGSYAHVILSEETNQAERPNQYLEQMPFLLF
PVAGDDRTSLLEALDKLQKSIAESADFSRSASLAFTTFQQQSQANYAVSITGRNKKELLREIESARKGINTAFDKGTDWQ
TPVGSYFTAQPLGKKGEVAYVYPAAVNSYIGIGRNLFRLFPKLHDNSFVKSLYKRAADIERLVFPRSLSKLSTRQLEQLE
KKLLSDSLAMFEAEIFCTRLLTTIIRDDFQVHPKYVFGYSLGETSMMVAQGIWSNFSEVSNSFNSSTLFGDRLSGPKNSV
REYWGLPKAATASGDNLWGNYVLMASPVQVRDAIRNEPRVYLTQINTPEEVLIAGDPAACQRVIKTIGCNSFTAPFDHVI
HCQAMRSEYDEFVQLNSLPVQDIADITFYSAAEYQPIKLETGVVAKSLATGLSQELDFPKLVNRIYDDGAKIFIEAGPGS
VCSRWIDKILEDKEHITVSLNRRGIDDHTSFVKALAKLVSHRVNVDLSPLYSPVIETSNLNKVTLRKITVGGDSISGKIL
SPENLQLFAEIREKKQQNIAPSGNALGINSTYLSHQKSLPKPKPFSAENIIEHGLKPEEPLKSSELTATQPAKPSDFLSN
TTTDIEFATIINMLDLNKAQYQKLNANNLQITQNHTAFLKARQDFSQQMSEIIQLQMVCAEDLLQEDGN

Sequences:

>Translated_1109_residues
MFAAENNNTAKIAIVGMDAFFGECNGLDAFERSIYDGKQHFITLPPKRWYGIDEQKDLLQEYGLTDGKAPVGAYIKDFDL
DTLAYKIPPNEVEKLNPQQLLLLTVADRALKDAKIPEGGNVAVIIAAEAELSVHKLQQRWDSSWQVKDGLNAAEITLPST
QVSQLESIVKDSVHHQVEIGEYLSYITNIMASRISSLWNFTGPSFTLTAVESSAFKAVEVAQMLLMTQEVDAVVVGAVDL
AGGVENVLLRSQTAPINTGANTLSYDQKANGWTVGEGAGAVVLKRHQQAIENGDRIYAVIDAISIGQSHTKVYGGSVNQA
CQQALKMAGVPPEQVKYVEVCASGIPQEDEAEIAGLVQAYPSVGDGLHCAIGSVKANIGHTFVASGIASLIKTALCLYYR
YIPATPNWSGVKTPQAFEGSPFYVVTESRPWFLSKNASRRIAAINGMGCDGSYAHVILSEETNQAERPNQYLEQMPFLLF
PVAGDDRTSLLEALDKLQKSIAESADFSRSASLAFTTFQQQSQANYAVSITGRNKKELLREIESARKGINTAFDKGTDWQ
TPVGSYFTAQPLGKKGEVAYVYPAAVNSYIGIGRNLFRLFPKLHDNSFVKSLYKRAADIERLVFPRSLSKLSTRQLEQLE
KKLLSDSLAMFEAEIFCTRLLTTIIRDDFQVHPKYVFGYSLGETSMMVAQGIWSNFSEVSNSFNSSTLFGDRLSGPKNSV
REYWGLPKAATASGDNLWGNYVLMASPVQVRDAIRNEPRVYLTQINTPEEVLIAGDPAACQRVIKTIGCNSFTAPFDHVI
HCQAMRSEYDEFVQLNSLPVQDIADITFYSAAEYQPIKLETGVVAKSLATGLSQELDFPKLVNRIYDDGAKIFIEAGPGS
VCSRWIDKILEDKEHITVSLNRRGIDDHTSFVKALAKLVSHRVNVDLSPLYSPVIETSNLNKVTLRKITVGGDSISGKIL
SPENLQLFAEIREKKQQNIAPSGNALGINSTYLSHQKSLPKPKPFSAENIIEHGLKPEEPLKSSELTATQPAKPSDFLSN
TTTDIEFATIINMLDLNKAQYQKLNANNLQITQNHTAFLKARQDFSQQMSEIIQLQMVCAEDLLQEDGN
>Mature_1109_residues
MFAAENNNTAKIAIVGMDAFFGECNGLDAFERSIYDGKQHFITLPPKRWYGIDEQKDLLQEYGLTDGKAPVGAYIKDFDL
DTLAYKIPPNEVEKLNPQQLLLLTVADRALKDAKIPEGGNVAVIIAAEAELSVHKLQQRWDSSWQVKDGLNAAEITLPST
QVSQLESIVKDSVHHQVEIGEYLSYITNIMASRISSLWNFTGPSFTLTAVESSAFKAVEVAQMLLMTQEVDAVVVGAVDL
AGGVENVLLRSQTAPINTGANTLSYDQKANGWTVGEGAGAVVLKRHQQAIENGDRIYAVIDAISIGQSHTKVYGGSVNQA
CQQALKMAGVPPEQVKYVEVCASGIPQEDEAEIAGLVQAYPSVGDGLHCAIGSVKANIGHTFVASGIASLIKTALCLYYR
YIPATPNWSGVKTPQAFEGSPFYVVTESRPWFLSKNASRRIAAINGMGCDGSYAHVILSEETNQAERPNQYLEQMPFLLF
PVAGDDRTSLLEALDKLQKSIAESADFSRSASLAFTTFQQQSQANYAVSITGRNKKELLREIESARKGINTAFDKGTDWQ
TPVGSYFTAQPLGKKGEVAYVYPAAVNSYIGIGRNLFRLFPKLHDNSFVKSLYKRAADIERLVFPRSLSKLSTRQLEQLE
KKLLSDSLAMFEAEIFCTRLLTTIIRDDFQVHPKYVFGYSLGETSMMVAQGIWSNFSEVSNSFNSSTLFGDRLSGPKNSV
REYWGLPKAATASGDNLWGNYVLMASPVQVRDAIRNEPRVYLTQINTPEEVLIAGDPAACQRVIKTIGCNSFTAPFDHVI
HCQAMRSEYDEFVQLNSLPVQDIADITFYSAAEYQPIKLETGVVAKSLATGLSQELDFPKLVNRIYDDGAKIFIEAGPGS
VCSRWIDKILEDKEHITVSLNRRGIDDHTSFVKALAKLVSHRVNVDLSPLYSPVIETSNLNKVTLRKITVGGDSISGKIL
SPENLQLFAEIREKKQQNIAPSGNALGINSTYLSHQKSLPKPKPFSAENIIEHGLKPEEPLKSSELTATQPAKPSDFLSN
TTTDIEFATIINMLDLNKAQYQKLNANNLQITQNHTAFLKARQDFSQQMSEIIQLQMVCAEDLLQEDGN

Specific function: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=484, Percent_Identity=24.5867768595041, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI8923559, Length=338, Percent_Identity=23.9644970414201, Blast_Score=75, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17550940, Length=402, Percent_Identity=24.6268656716418, Blast_Score=93, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI212642053, Length=462, Percent_Identity=24.6753246753247, Blast_Score=90, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24581345, Length=475, Percent_Identity=26.3157894736842, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI221330659, Length=714, Percent_Identity=21.7086834733894, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920632, Length=708, Percent_Identity=21.7514124293785, Blast_Score=98, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009081
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR011254
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 122037; Mature: 122037

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAAENNNTAKIAIVGMDAFFGECNGLDAFERSIYDGKQHFITLPPKRWYGIDEQKDLLQ
CCCCCCCCEEEEEEEEEHHHHCCCCCCHHHHHHHHCCCCCEEECCCHHHCCCCHHHHHHH
EYGLTDGKAPVGAYIKDFDLDTLAYKIPPNEVEKLNPQQLLLLTVADRALKDAKIPEGGN
HCCCCCCCCCCCCHHHCCCCCCEEEECCCHHHHHCCHHHEEEEHHHHHHHHHCCCCCCCC
VAVIIAAEAELSVHKLQQRWDSSWQVKDGLNAAEITLPSTQVSQLESIVKDSVHHQVEIG
EEEEEEECCHHHHHHHHHHHCCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
EYLSYITNIMASRISSLWNFTGPSFTLTAVESSAFKAVEVAQMLLMTQEVDAVVVGAVDL
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCEEEEEHHHH
AGGVENVLLRSQTAPINTGANTLSYDQKANGWTVGEGAGAVVLKRHQQAIENGDRIYAVI
HCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEE
DAISIGQSHTKVYGGSVNQACQQALKMAGVPPEQVKYVEVCASGIPQEDEAEIAGLVQAY
EHHHCCCCHHEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
PSVGDGLHCAIGSVKANIGHTFVASGIASLIKTALCLYYRYIPATPNWSGVKTPQAFEGS
CCCCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PFYVVTESRPWFLSKNASRRIAAINGMGCDGSYAHVILSEETNQAERPNQYLEQMPFLLF
CEEEEECCCCEEECCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHCCEEEE
PVAGDDRTSLLEALDKLQKSIAESADFSRSASLAFTTFQQQSQANYAVSITGRNKKELLR
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHCCCCEEEEEECCCHHHHHH
EIESARKGINTAFDKGTDWQTPVGSYFTAQPLGKKGEVAYVYPAAVNSYIGIGRNLFRLF
HHHHHHHCCCHHHCCCCCCCCCCCCCEECCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHH
PKLHDNSFVKSLYKRAADIERLVFPRSLSKLSTRQLEQLEKKLLSDSLAMFEAEIFCTRL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTTIIRDDFQVHPKYVFGYSLGETSMMVAQGIWSNFSEVSNSFNSSTLFGDRLSGPKNSV
HHHHHHCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHH
REYWGLPKAATASGDNLWGNYVLMASPVQVRDAIRNEPRVYLTQINTPEEVLIAGDPAAC
HHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCEEEEECCCCCEEEEECCHHHH
QRVIKTIGCNSFTAPFDHVIHCQAMRSEYDEFVQLNSLPVQDIADITFYSAAEYQPIKLE
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCEEEC
TGVVAKSLATGLSQELDFPKLVNRIYDDGAKIFIEAGPGSVCSRWIDKILEDKEHITVSL
CHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEE
NRRGIDDHTSFVKALAKLVSHRVNVDLSPLYSPVIETSNLNKVTLRKITVGGDSISGKIL
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCEE
SPENLQLFAEIREKKQQNIAPSGNALGINSTYLSHQKSLPKPKPFSAENIIEHGLKPEEP
CCCHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCC
LKSSELTATQPAKPSDFLSNTTTDIEFATIINMLDLNKAQYQKLNANNLQITQNHTAFLK
CCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCEEEECCCHHHHH
ARQDFSQQMSEIIQLQMVCAEDLLQEDGN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFAAENNNTAKIAIVGMDAFFGECNGLDAFERSIYDGKQHFITLPPKRWYGIDEQKDLLQ
CCCCCCCCEEEEEEEEEHHHHCCCCCCHHHHHHHHCCCCCEEECCCHHHCCCCHHHHHHH
EYGLTDGKAPVGAYIKDFDLDTLAYKIPPNEVEKLNPQQLLLLTVADRALKDAKIPEGGN
HCCCCCCCCCCCCHHHCCCCCCEEEECCCHHHHHCCHHHEEEEHHHHHHHHHCCCCCCCC
VAVIIAAEAELSVHKLQQRWDSSWQVKDGLNAAEITLPSTQVSQLESIVKDSVHHQVEIG
EEEEEEECCHHHHHHHHHHHCCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
EYLSYITNIMASRISSLWNFTGPSFTLTAVESSAFKAVEVAQMLLMTQEVDAVVVGAVDL
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCEEEEEHHHH
AGGVENVLLRSQTAPINTGANTLSYDQKANGWTVGEGAGAVVLKRHQQAIENGDRIYAVI
HCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEE
DAISIGQSHTKVYGGSVNQACQQALKMAGVPPEQVKYVEVCASGIPQEDEAEIAGLVQAY
EHHHCCCCHHEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
PSVGDGLHCAIGSVKANIGHTFVASGIASLIKTALCLYYRYIPATPNWSGVKTPQAFEGS
CCCCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PFYVVTESRPWFLSKNASRRIAAINGMGCDGSYAHVILSEETNQAERPNQYLEQMPFLLF
CEEEEECCCCEEECCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHCCEEEE
PVAGDDRTSLLEALDKLQKSIAESADFSRSASLAFTTFQQQSQANYAVSITGRNKKELLR
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHCCCCEEEEEECCCHHHHHH
EIESARKGINTAFDKGTDWQTPVGSYFTAQPLGKKGEVAYVYPAAVNSYIGIGRNLFRLF
HHHHHHHCCCHHHCCCCCCCCCCCCCEECCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHH
PKLHDNSFVKSLYKRAADIERLVFPRSLSKLSTRQLEQLEKKLLSDSLAMFEAEIFCTRL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTTIIRDDFQVHPKYVFGYSLGETSMMVAQGIWSNFSEVSNSFNSSTLFGDRLSGPKNSV
HHHHHHCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHH
REYWGLPKAATASGDNLWGNYVLMASPVQVRDAIRNEPRVYLTQINTPEEVLIAGDPAAC
HHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCEEEEECCCCCEEEEECCHHHH
QRVIKTIGCNSFTAPFDHVIHCQAMRSEYDEFVQLNSLPVQDIADITFYSAAEYQPIKLE
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCEEEC
TGVVAKSLATGLSQELDFPKLVNRIYDDGAKIFIEAGPGSVCSRWIDKILEDKEHITVSL
CHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEE
NRRGIDDHTSFVKALAKLVSHRVNVDLSPLYSPVIETSNLNKVTLRKITVGGDSISGKIL
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCEE
SPENLQLFAEIREKKQQNIAPSGNALGINSTYLSHQKSLPKPKPFSAENIIEHGLKPEEP
CCCHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCC
LKSSELTATQPAKPSDFLSNTTTDIEFATIINMLDLNKAQYQKLNANNLQITQNHTAFLK
CCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCEEEECCCHHHHH
ARQDFSQQMSEIIQLQMVCAEDLLQEDGN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8344529; 9384377; 10568751 [H]