Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 75908534

GI number: 75908534

Start: 2878682

End: 2879680

Strand: Direct

Name: thiL [H]

Synonym: Ava_2317

Alternate gene names: 75908534

Gene position: 2878682-2879680 (Clockwise)

Preceding gene: 75908533

Following gene: 75908537

Centisome position: 45.22

GC content: 46.35

Gene sequence:

>999_bases
ATGACCACAGTTAAAGATATTGGCGAACAAGGACTATTGAAAATATTGCAGCGCTTTTGTCCACCAGAAATTATTGGTGA
TGATGCGGCGGTGTTGGTGACAGAACCAGAGCAGTCTTTAGTTGTCACTACAGATATGCTGGTTGATGGGGTGCATTTTA
GCGATGTCACAACTTCCCCAGAAGATGCGGGATGGCGTGCTGCGGCTGCGAATTTGTCAGATTTAGCGGCGATGGGTGCT
ACTCCTTTGGGTATTACTATTGCGTTGGCGCTTCCTGGGGATTTGAGCGTGAGTTGGGTAGAACGCTTATACCAAGGAAT
TACAGAATGCCTACAAAAATACAATACTCCCATTGTTGGTGGAGATGTGGTGCGATCGCCTATCACTACTCTATCCATTA
CCGCTTTTGGTCAAGTCCACCCCAATAGGATTATCCGCCGTTCTACTGCTCAAGTTGGGGATGCGATCGCAGTTACAGGT
ATTCACGGAGCCTCCCATGCGGGTTTAAAGTTGCTTCTAGACCCCAAAACAGGAAAAGACCTTACCCCCGAAGAAAAGGC
GGCTTTAATTAAAGCCCACCAGCGTCCCCAGCCACGTTTAGATGTTCTTCCCTATCTCTGGCAAATCTCCCAATCTCCAT
TCCCTATCACCGGTATGGATAGCAGCGATGGTTTAGCGGATGCTGTACTACAAATCTGCCGAACCAGTGGTGTTGGTGCT
GTTATAGAAAGCGACCAAATACCCCTACCAACAGCCTTCAACCACTGGCTAACACCAGAACAAGCTTTAAATTATGCTTT
ATACGGCGGTGAAGATTTTGAATTAGTGTTGTGTTTACCACCAGACCTAGCAAAAACCCTAGTACAAAATTTGGGTCAAA
GTGCAGCTATTATTGGCACCATTACATCAGATACCGACGTGATACTGCACCATCGAAACACAAAAATCCCTGACCAAGTA
CTCACCCTCAGTCAGGGATTTCAACATTTTAGTCACTAG

Upstream 100 bases:

>100_bases
AACAGATAACCTGTTTGCGTAAGTCCTAGTTCAGAGTGAGAAGGCAATAAACAATACTCAGTTGTTACTTGTCTTTCTCT
CTCATCCCTCATTCCTTCCA

Downstream 100 bases:

>100_bases
GATTAATTGCTAGTTGTCACTGCTTAGTAATACTAAACACAACTAACAACTAACAATTGACCAAATTAACTTAAACCCAT
TTTTCAGCCACTAATTCTGC

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTTVKDIGEQGLLKILQRFCPPEIIGDDAAVLVTEPEQSLVVTTDMLVDGVHFSDVTTSPEDAGWRAAAANLSDLAAMGA
TPLGITIALALPGDLSVSWVERLYQGITECLQKYNTPIVGGDVVRSPITTLSITAFGQVHPNRIIRRSTAQVGDAIAVTG
IHGASHAGLKLLLDPKTGKDLTPEEKAALIKAHQRPQPRLDVLPYLWQISQSPFPITGMDSSDGLADAVLQICRTSGVGA
VIESDQIPLPTAFNHWLTPEQALNYALYGGEDFELVLCLPPDLAKTLVQNLGQSAAIIGTITSDTDVILHHRNTKIPDQV
LTLSQGFQHFSH

Sequences:

>Translated_332_residues
MTTVKDIGEQGLLKILQRFCPPEIIGDDAAVLVTEPEQSLVVTTDMLVDGVHFSDVTTSPEDAGWRAAAANLSDLAAMGA
TPLGITIALALPGDLSVSWVERLYQGITECLQKYNTPIVGGDVVRSPITTLSITAFGQVHPNRIIRRSTAQVGDAIAVTG
IHGASHAGLKLLLDPKTGKDLTPEEKAALIKAHQRPQPRLDVLPYLWQISQSPFPITGMDSSDGLADAVLQICRTSGVGA
VIESDQIPLPTAFNHWLTPEQALNYALYGGEDFELVLCLPPDLAKTLVQNLGQSAAIIGTITSDTDVILHHRNTKIPDQV
LTLSQGFQHFSH
>Mature_331_residues
TTVKDIGEQGLLKILQRFCPPEIIGDDAAVLVTEPEQSLVVTTDMLVDGVHFSDVTTSPEDAGWRAAAANLSDLAAMGAT
PLGITIALALPGDLSVSWVERLYQGITECLQKYNTPIVGGDVVRSPITTLSITAFGQVHPNRIIRRSTAQVGDAIAVTGI
HGASHAGLKLLLDPKTGKDLTPEEKAALIKAHQRPQPRLDVLPYLWQISQSPFPITGMDSSDGLADAVLQICRTSGVGAV
IESDQIPLPTAFNHWLTPEQALNYALYGGEDFELVLCLPPDLAKTLVQNLGQSAAIIGTITSDTDVILHHRNTKIPDQVL
TLSQGFQHFSH

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=313, Percent_Identity=37.3801916932907, Blast_Score=158, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35570; Mature: 35439

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVKDIGEQGLLKILQRFCPPEIIGDDAAVLVTEPEQSLVVTTDMLVDGVHFSDVTTSP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEHHHHHCCCCCCCCCCCC
EDAGWRAAAANLSDLAAMGATPLGITIALALPGDLSVSWVERLYQGITECLQKYNTPIVG
CCCCCHHHHCCHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
GDVVRSPITTLSITAFGQVHPNRIIRRSTAQVGDAIAVTGIHGASHAGLKLLLDPKTGKD
CHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEECCCCCCC
LTPEEKAALIKAHQRPQPRLDVLPYLWQISQSPFPITGMDSSDGLADAVLQICRTSGVGA
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHCCCCCE
VIESDQIPLPTAFNHWLTPEQALNYALYGGEDFELVLCLPPDLAKTLVQNLGQSAAIIGT
EEECCCCCCCCCHHCCCCHHHHHCEEEECCCCCEEEEECCCHHHHHHHHHCCCCEEEEEE
ITSDTDVILHHRNTKIPDQVLTLSQGFQHFSH
ECCCCEEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTVKDIGEQGLLKILQRFCPPEIIGDDAAVLVTEPEQSLVVTTDMLVDGVHFSDVTTSP
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEHHHHHCCCCCCCCCCCC
EDAGWRAAAANLSDLAAMGATPLGITIALALPGDLSVSWVERLYQGITECLQKYNTPIVG
CCCCCHHHHCCHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
GDVVRSPITTLSITAFGQVHPNRIIRRSTAQVGDAIAVTGIHGASHAGLKLLLDPKTGKD
CHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEECCCCCCC
LTPEEKAALIKAHQRPQPRLDVLPYLWQISQSPFPITGMDSSDGLADAVLQICRTSGVGA
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHCCCCCE
VIESDQIPLPTAFNHWLTPEQALNYALYGGEDFELVLCLPPDLAKTLVQNLGQSAAIIGT
EEECCCCCCCCCHHCCCCHHHHHCEEEECCCCCEEEEECCCHHHHHHHHHCCCCEEEEEE
ITSDTDVILHHRNTKIPDQVLTLSQGFQHFSH
ECCCCEEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA