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The map label for this gene is ppnK [H]

Identifier: 75908142

GI number: 75908142

Start: 2384636

End: 2385622

Strand: Direct

Name: ppnK [H]

Synonym: Ava_1921

Alternate gene names: 75908142

Gene position: 2384636-2385622 (Clockwise)

Preceding gene: 75908141

Following gene: 75908143

Centisome position: 37.46

GC content: 47.42

Gene sequence:

>987_bases
ATGACTGGTGATCCAAAATGTGTAACGATTACAAAAGACAAAGCGTCGCTTAAACTTGGATATTTGAGTGTGCCGAAAGT
AGGCATTATATACAACGACATTAAACCGGTAGCCGGTCGTGTTGCTATCGAGTTAAAAGATAAGCTAACCACAGCCGGTT
GGGATGTATCTATCACATCTAGTATCGGTGGCATATTGGGCTACTCTAATCCCGAAAGCCCTGTGTGCCACACACCAATT
GACGGTTTGACACCCCCTGGTTTTGATTCAGAGATGAAGTTTGCCATAGTGCTGGGGGGCGATGGTACTGTTTTAGCCGC
ATCGCGTCAGGTAGCGCCTTGCGGTATCCCGATTTTGGCCATCAATACCGGACACATGGGGTTCCTAACGGAAACTTACC
TAAATCAATTACCCCAAGCTATAGATCAGGCGATCGCCGGTGAGTATGAAATCGAAGAACGAGCCATGCTCACAGTCAAA
GTGCTACGAGGAGAATCAGTACTTTGGGAGGCTCTATGCTTGAACGAAATGGTTTTGCATCGTGAACCATTAACGTCAAT
GTGTCATTTTGAGATTGCTGTAGGTCGTCATGCGCCAGTTGATATTGCCGCAGATGGGGTAATTGTTTCTACGCCTACAG
GCTCCACCGCTTACTCTTTAAGCGCAGGTGGGCCAGTTGTCACCCCCGGCGTACCCGCATTGCAGCTCGTTCCTATTTGT
CCCCATTCTTTGGCTTCTAGGGCTTTGGTATTTCCCGATACTGAACCAGTCAATATTTACCCGGTGAACATTCCCCGGTT
GGTGATGGTAGTCGATGGCAACGGGGGATGCTATATTTTTCCCGAAGATAGAGTATATCTGGAGCGCTCGCCATACAGTG
TCAAATTTATTCGCCTCCAACCACCAGAATTTTTCCGTATTTTGCGAGAAAAACTGGGTTGGGGTCTACCGCATATCGCC
AAACCAACTTCAGTAGAATTACCTTAG

Upstream 100 bases:

>100_bases
AAAAACTCCCTTTAAAAAAGTCAATAGTTAATAGTCGCCAGTCAACAGTCAGTAATCAACAGTTTTTTACCATAGAGTAT
AGACTTTTGATGCCAAACTA

Downstream 100 bases:

>100_bases
TCAATAGTCAATAGTTATTCCCCTTTCCCCCACTCCCCATTTATTGCCTATACAATTAAACATCCTAATATCCCCAAATC
TTATGATAGCTACTCATAGC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTGDPKCVTITKDKASLKLGYLSVPKVGIIYNDIKPVAGRVAIELKDKLTTAGWDVSITSSIGGILGYSNPESPVCHTPI
DGLTPPGFDSEMKFAIVLGGDGTVLAASRQVAPCGIPILAINTGHMGFLTETYLNQLPQAIDQAIAGEYEIEERAMLTVK
VLRGESVLWEALCLNEMVLHREPLTSMCHFEIAVGRHAPVDIAADGVIVSTPTGSTAYSLSAGGPVVTPGVPALQLVPIC
PHSLASRALVFPDTEPVNIYPVNIPRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQPPEFFRILREKLGWGLPHIA
KPTSVELP

Sequences:

>Translated_328_residues
MTGDPKCVTITKDKASLKLGYLSVPKVGIIYNDIKPVAGRVAIELKDKLTTAGWDVSITSSIGGILGYSNPESPVCHTPI
DGLTPPGFDSEMKFAIVLGGDGTVLAASRQVAPCGIPILAINTGHMGFLTETYLNQLPQAIDQAIAGEYEIEERAMLTVK
VLRGESVLWEALCLNEMVLHREPLTSMCHFEIAVGRHAPVDIAADGVIVSTPTGSTAYSLSAGGPVVTPGVPALQLVPIC
PHSLASRALVFPDTEPVNIYPVNIPRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQPPEFFRILREKLGWGLPHIA
KPTSVELP
>Mature_327_residues
TGDPKCVTITKDKASLKLGYLSVPKVGIIYNDIKPVAGRVAIELKDKLTTAGWDVSITSSIGGILGYSNPESPVCHTPID
GLTPPGFDSEMKFAIVLGGDGTVLAASRQVAPCGIPILAINTGHMGFLTETYLNQLPQAIDQAIAGEYEIEERAMLTVKV
LRGESVLWEALCLNEMVLHREPLTSMCHFEIAVGRHAPVDIAADGVIVSTPTGSTAYSLSAGGPVVTPGVPALQLVPICP
HSLASRALVFPDTEPVNIYPVNIPRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQPPEFFRILREKLGWGLPHIAK
PTSVELP

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=257, Percent_Identity=30.7392996108949, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1788968, Length=289, Percent_Identity=31.1418685121107, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320794, Length=257, Percent_Identity=32.6848249027237, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6322509, Length=244, Percent_Identity=31.9672131147541, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6325068, Length=168, Percent_Identity=33.9285714285714, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573828, Length=253, Percent_Identity=29.2490118577075, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573832, Length=254, Percent_Identity=29.1338582677165, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573826, Length=254, Percent_Identity=29.1338582677165, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573830, Length=254, Percent_Identity=29.1338582677165, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161077047, Length=253, Percent_Identity=29.2490118577075, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20129957, Length=278, Percent_Identity=27.6978417266187, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281363321, Length=278, Percent_Identity=27.6978417266187, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653422, Length=278, Percent_Identity=27.6978417266187, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653424, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363323, Length=278, Percent_Identity=27.6978417266187, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 35250; Mature: 35119

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDPKCVTITKDKASLKLGYLSVPKVGIIYNDIKPVAGRVAIELKDKLTTAGWDVSITS
CCCCCEEEEEECCCCEEEEEEEECCCEEEEEECCCCCCCEEEEEEECCEEECCCCEEECC
SIGGILGYSNPESPVCHTPIDGLTPPGFDSEMKFAIVLGGDGTVLAASRQVAPCGIPILA
CCCCEECCCCCCCCEEECCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEEE
INTGHMGFLTETYLNQLPQAIDQAIAGEYEIEERAMLTVKVLRGESVLWEALCLNEMVLH
EECCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEEECCCHHHHHHHHHHHHHHC
REPLTSMCHFEIAVGRHAPVDIAADGVIVSTPTGSTAYSLSAGGPVVTPGVPALQLVPIC
CCCCHHHEEEEEEECCCCCCEEEECCEEEECCCCCCEEEECCCCCEECCCCCCEEEEECC
PHSLASRALVFPDTEPVNIYPVNIPRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQ
CHHHHCCEEECCCCCCCEEEEECCCEEEEEEECCCCEEEEECCEEEEECCCCEEEEEEEC
PPEFFRILREKLGWGLPHIAKPTSVELP
CHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGDPKCVTITKDKASLKLGYLSVPKVGIIYNDIKPVAGRVAIELKDKLTTAGWDVSITS
CCCCEEEEEECCCCEEEEEEEECCCEEEEEECCCCCCCEEEEEEECCEEECCCCEEECC
SIGGILGYSNPESPVCHTPIDGLTPPGFDSEMKFAIVLGGDGTVLAASRQVAPCGIPILA
CCCCEECCCCCCCCEEECCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEEE
INTGHMGFLTETYLNQLPQAIDQAIAGEYEIEERAMLTVKVLRGESVLWEALCLNEMVLH
EECCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEEECCCHHHHHHHHHHHHHHC
REPLTSMCHFEIAVGRHAPVDIAADGVIVSTPTGSTAYSLSAGGPVVTPGVPALQLVPIC
CCCCHHHEEEEEEECCCCCCEEEECCEEEECCCCCCEEEECCCCCEECCCCCCEEEEECC
PHSLASRALVFPDTEPVNIYPVNIPRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQ
CHHHHCCEEECCCCCCCEEEEECCCEEEEEEECCCCEEEEECCEEEEECCCCEEEEEEEC
PPEFFRILREKLGWGLPHIAKPTSVELP
CHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA