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The map label for this gene is trpD [H]

Identifier: 75676028

GI number: 75676028

Start: 2011216

End: 2012229

Strand: Direct

Name: trpD [H]

Synonym: Nwi_1837

Alternate gene names: 75676028

Gene position: 2011216-2012229 (Clockwise)

Preceding gene: 75676027

Following gene: 75676029

Centisome position: 59.12

GC content: 67.55

Gene sequence:

>1014_bases
ATGGACGATCTCAAGGTTCTCATTGGAAAGGTCGCCACCGGCGCGACACTGACGCGGGAGGAAGCCGCCGCCGCGTTCAA
CAGCATGATGTCCGGCGAAGCGACTCCCTCGCAGATGGGCGGCCTTTTGATGGCGCTGCGCGTGCGCGGGGAAACCGTCG
ACGAGATCACCGGGGCGGTCTCGGCGATGAGATCCATGATGCTGCGGGTCAAGGCGCCCGTGGATGCGGTCGACGTCGTC
GGCACCGGCGGCGACGGCTCGGGCTCGGTGAATGTCTCGACCTGCGCGTCATTCATCGTCGCAGGCGCCGGCGTGACCGT
CGCCAAGCACGGCAATCGCGCGCTGTCCTCCAGATCCGGGGCCGCCGACTGTCTCGCCGCGCTCGGCATCAGGATCGACC
TCACCCCCGAACAGGTCGGCCGCTGCATCAACGAGGCCGGCATCGGCTTCATGTTCGCGCCCGCGCATCACCCCGCGATG
AAGAATGTCGGCCCGACCCGCGTCGAACTCGCGACCCGCACCATCTTCAACCTGCTGGGACCGCTGTCCAATCCCGCGGG
CGTCAGGCGGCAGATGGTCGGCGTGTTCTCGCGGCAATGGGTGCAGCCGCTGGCGCAGGTGCTCAAGAATCACGGCTCGG
AATCGGCATGGGTCGTTCACGGCTCGGACGGCCTGGACGAGATCACCCTCGCCGGCCCGACATTCGTCGCCGCACTCGAA
GACGGCAATATCCGCACCTTCGAGGTGACGCCTGAAGATGCGGGACTGGAGCGCGCCGACGGCGACGCGCTGAAAGGCGG
AGACGCCGAGGCGAACGCGGCCTCCTTGCGCGCGGTGCTCGAAGGCAAGCCGGGCGCCTTCCGCGATGTCGCGCTGCTCA
ACGCGGCGGCGGCGCTGATCGTGGCCGGCAAGGCGAAGACCTTGAAGGAGGGTGTCGCGCTTGGGGCGAAATCGCTCGAC
GGCGGCGGCGCGCTGAACAAGCTGAAGCAATTGATCGCGGTTTCCAACGGTTGA

Upstream 100 bases:

>100_bases
GATCGGCACCAAGATCAATCAGGCGGCGGTGGCGCAGATCACCGGCGCCAGCAGCAACTTCTGACGAGAACCGGCGAGCG
CCGCATCCCGAAAGCATCCG

Downstream 100 bases:

>100_bases
GGACGATGGCGTGGCCGACATCCTGACCAGGATCGAAACCTACAAGCGCGAGGAGATCGCGAGCGCAAAGCGTGCACGTC
CCCTCGGCGAGGTCACGGCC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MDDLKVLIGKVATGATLTREEAAAAFNSMMSGEATPSQMGGLLMALRVRGETVDEITGAVSAMRSMMLRVKAPVDAVDVV
GTGGDGSGSVNVSTCASFIVAGAGVTVAKHGNRALSSRSGAADCLAALGIRIDLTPEQVGRCINEAGIGFMFAPAHHPAM
KNVGPTRVELATRTIFNLLGPLSNPAGVRRQMVGVFSRQWVQPLAQVLKNHGSESAWVVHGSDGLDEITLAGPTFVAALE
DGNIRTFEVTPEDAGLERADGDALKGGDAEANAASLRAVLEGKPGAFRDVALLNAAAALIVAGKAKTLKEGVALGAKSLD
GGGALNKLKQLIAVSNG

Sequences:

>Translated_337_residues
MDDLKVLIGKVATGATLTREEAAAAFNSMMSGEATPSQMGGLLMALRVRGETVDEITGAVSAMRSMMLRVKAPVDAVDVV
GTGGDGSGSVNVSTCASFIVAGAGVTVAKHGNRALSSRSGAADCLAALGIRIDLTPEQVGRCINEAGIGFMFAPAHHPAM
KNVGPTRVELATRTIFNLLGPLSNPAGVRRQMVGVFSRQWVQPLAQVLKNHGSESAWVVHGSDGLDEITLAGPTFVAALE
DGNIRTFEVTPEDAGLERADGDALKGGDAEANAASLRAVLEGKPGAFRDVALLNAAAALIVAGKAKTLKEGVALGAKSLD
GGGALNKLKQLIAVSNG
>Mature_337_residues
MDDLKVLIGKVATGATLTREEAAAAFNSMMSGEATPSQMGGLLMALRVRGETVDEITGAVSAMRSMMLRVKAPVDAVDVV
GTGGDGSGSVNVSTCASFIVAGAGVTVAKHGNRALSSRSGAADCLAALGIRIDLTPEQVGRCINEAGIGFMFAPAHHPAM
KNVGPTRVELATRTIFNLLGPLSNPAGVRRQMVGVFSRQWVQPLAQVLKNHGSESAWVVHGSDGLDEITLAGPTFVAALE
DGNIRTFEVTPEDAGLERADGDALKGGDAEANAASLRAVLEGKPGAFRDVALLNAAAALIVAGKAKTLKEGVALGAKSLD
GGGALNKLKQLIAVSNG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=284, Percent_Identity=40.8450704225352, Blast_Score=220, Evalue=9e-59,
Organism=Saccharomyces cerevisiae, GI6320561, Length=325, Percent_Identity=31.0769230769231, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 34375; Mature: 34375

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDLKVLIGKVATGATLTREEAAAAFNSMMSGEATPSQMGGLLMALRVRGETVDEITGAV
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHEEEEHHCCCHHHHHHHHH
SAMRSMMLRVKAPVDAVDVVGTGGDGSGSVNVSTCASFIVAGAGVTVAKHGNRALSSRSG
HHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHCCCEEEEECCCHHHHCCCC
AADCLAALGIRIDLTPEQVGRCINEAGIGFMFAPAHHPAMKNVGPTRVELATRTIFNLLG
HHHHHHHHCCEEEECHHHHHHHHHHCCCCEEECCCCCCHHHCCCCHHHHHHHHHHHHHHC
PLSNPAGVRRQMVGVFSRQWVQPLAQVLKNHGSESAWVVHGSDGLDEITLAGPTFVAALE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCEEEEEEE
DGNIRTFEVTPEDAGLERADGDALKGGDAEANAASLRAVLEGKPGAFRDVALLNAAAALI
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VAGKAKTLKEGVALGAKSLDGGGALNKLKQLIAVSNG
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDDLKVLIGKVATGATLTREEAAAAFNSMMSGEATPSQMGGLLMALRVRGETVDEITGAV
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHEEEEHHCCCHHHHHHHHH
SAMRSMMLRVKAPVDAVDVVGTGGDGSGSVNVSTCASFIVAGAGVTVAKHGNRALSSRSG
HHHHHHHHHHCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHCCCEEEEECCCHHHHCCCC
AADCLAALGIRIDLTPEQVGRCINEAGIGFMFAPAHHPAMKNVGPTRVELATRTIFNLLG
HHHHHHHHCCEEEECHHHHHHHHHHCCCCEEECCCCCCHHHCCCCHHHHHHHHHHHHHHC
PLSNPAGVRRQMVGVFSRQWVQPLAQVLKNHGSESAWVVHGSDGLDEITLAGPTFVAALE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCEEEEEEE
DGNIRTFEVTPEDAGLERADGDALKGGDAEANAASLRAVLEGKPGAFRDVALLNAAAALI
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VAGKAKTLKEGVALGAKSLDGGGALNKLKQLIAVSNG
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA