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The map label for this gene is ppiD [H]

Identifier: 75676027

GI number: 75676027

Start: 2009269

End: 2011179

Strand: Direct

Name: ppiD [H]

Synonym: Nwi_1836

Alternate gene names: 75676027

Gene position: 2009269-2011179 (Clockwise)

Preceding gene: 75676023

Following gene: 75676028

Centisome position: 59.06

GC content: 64.42

Gene sequence:

>1911_bases
ATGCTTCGAGGAATACGCAACGCCTCATCAAACTGGCTCGGCAAGACCCTCATGACGATCGTGATGGGCCTGTTGATCGT
CGCCTTCGGCATCTGGGGCATCGCGGACATCTTTCACGGCTTCGGCCAGTCCGCGCTGGCCACGGTGGGCGGCACCGAGA
TTTCGACCGAGCAGTTCCGGCAGATCTACAACGACCGGCTGCAACAGATCGGACGCCAGTTCGGCCGCCCGCTGCCTCCC
GATCAGGTCAGGGCTCTCGGCCTCGACCGCCAGATCCTGCAGCAGGTGATCGCGGAGGCAGCGCTCGACGAAGACGCCCA
GCGCAAGGGTCTCAAGGTGTCGGACGAGGAGATCGGCCGACAGATCAAGAGCGATCCCAACTTCAAGGGTGCGAATAACG
CCTTCGACGCGGCGCGTTTCGCCGGCCTCATCCGCCAGCTGGGATACACCGAGCAGCGCTACGTCGCCGAGCAGCGAAAC
ATGGCGCTGCGCCGCCAGATCGTCGGAACGATGACGGCCGGCGTCGAGCCCTCGAAAACGCTGCTGGAGGCGTTGAACCG
CTTCCAGAACGAGCAGCGGACCATCGACTACGTCAAGCTCGGCGCGGCGCAGGCCGGAACCATCGATCCTCCCACGGCGG
ACCAGTTGTCCGGATATTTCGACGCCCACAAGGTGCAGTTCCGCGCGCCGGAATATCGCAAGGTGGCTTTCGTGGTCTTG
ACGCCCGAGGAAGTCGCCAAATGGACCGCCGTGTCCGACGACGACGCCAGAAAAATCTACGAGGAGCGCAAGGACAAGCT
GTCCACGCCCGAACGGCGACAACTCCGGCAGATCATGTTCCCCAGCGTCACGGACGCCCAGGCCGCGCGGGAGAAGATCG
CCGGCGGCGCGTCGTTCGACGACATCGCCAGGGAGCGCGGCCTTGCGACCTCGGACATCGACCTTGGCACGATCTCGAAA
GCCGAGATCATCGATCCCGCCATCGCCAATGCAGCGTTCTCGATCAACAGCGATGAAGTCAGCCAGCCGACCCAGGGTCG
ATTTGGAGTCGCGCTGATCAAGGTCGGCCGCATTGAGCCGGGCAACCAGCCGACTTATGAAAGCGTTGCCGAAAAACTGA
AGCGCGACGTCGCGCTCGACCGCGCGCGCGCTGAAATCAACAACCTCCACAACAAGATGGAGGACGAGCGCGGAGGCGGC
GCGAGCGTTGTCGAAGCGGCCAAGAAAGTCGGGCTGTCCGCGGTCACCATCGAAGCCACCGACCGCTCCGGGCGCGCGCC
GGACGGCAAACCCGTGTCTGGAATTCCGCAGGGCGTCGACCTGATCGCGCAGGCGTTCGCCAGCGATGTCGGCGTCGACA
ACGACACGCTGCAACTCGGCAACAACGGCTTCATCTGGTTCGACGTTATCGGCGTCACCCCCTCGCGTGACCGCACGCTC
GACGAGGTCAAGGACAAGGTCGAAGCGAGGTGGCGCGAAGACCAGATCAGCAGCCGCCTGATGACCAAAGCGACGGATAC
GATCCGCAAACTTGAGCAGGGCGGCAAGCTCGCCGACGAGGCGGCCAGCCTCGGTCTCAAGGTCGAGAGCGCGAGCGCGA
TCAAGCGGGACGCCACGACGACCGCCCTTCCCGCCGCCGTGGTCGCCGCCGTATGCCGCGCCGCCAAGGACGCAGCCGGC
CAGGCGCCCGGCGCGGGCAATGACGAATGGTTCATTTTCCGCGTCACCGACGTGAAGGTGCCGACGCTCGATCTCGCCTC
CGATGAGACGAAAAAGCTGCGTGAAGGCGTCCAGCGCGGCCTGTCGGATGAGTATATCGGCCAGTACATCGTCAAGCTCG
AAGCCGAGATCGGCACCAAGATCAATCAGGCGGCGGTGGCGCAGATCACCGGCGCCAGCAGCAACTTCTGA

Upstream 100 bases:

>100_bases
AGTGCGACCCGCTTCCCATACGACCTGCTTCCCATACGACCTGCTTCCCATACGACCTGCTTCCCATACGACCTGCTTCC
CTCCTGCAAAAGACGGACTC

Downstream 100 bases:

>100_bases
CGAGAACCGGCGAGCGCCGCATCCCGAAAGCATCCGATGGACGATCTCAAGGTTCTCATTGGAAAGGTCGCCACCGGCGC
GACACTGACGCGGGAGGAAG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MLRGIRNASSNWLGKTLMTIVMGLLIVAFGIWGIADIFHGFGQSALATVGGTEISTEQFRQIYNDRLQQIGRQFGRPLPP
DQVRALGLDRQILQQVIAEAALDEDAQRKGLKVSDEEIGRQIKSDPNFKGANNAFDAARFAGLIRQLGYTEQRYVAEQRN
MALRRQIVGTMTAGVEPSKTLLEALNRFQNEQRTIDYVKLGAAQAGTIDPPTADQLSGYFDAHKVQFRAPEYRKVAFVVL
TPEEVAKWTAVSDDDARKIYEERKDKLSTPERRQLRQIMFPSVTDAQAAREKIAGGASFDDIARERGLATSDIDLGTISK
AEIIDPAIANAAFSINSDEVSQPTQGRFGVALIKVGRIEPGNQPTYESVAEKLKRDVALDRARAEINNLHNKMEDERGGG
ASVVEAAKKVGLSAVTIEATDRSGRAPDGKPVSGIPQGVDLIAQAFASDVGVDNDTLQLGNNGFIWFDVIGVTPSRDRTL
DEVKDKVEARWREDQISSRLMTKATDTIRKLEQGGKLADEAASLGLKVESASAIKRDATTTALPAAVVAAVCRAAKDAAG
QAPGAGNDEWFIFRVTDVKVPTLDLASDETKKLREGVQRGLSDEYIGQYIVKLEAEIGTKINQAAVAQITGASSNF

Sequences:

>Translated_636_residues
MLRGIRNASSNWLGKTLMTIVMGLLIVAFGIWGIADIFHGFGQSALATVGGTEISTEQFRQIYNDRLQQIGRQFGRPLPP
DQVRALGLDRQILQQVIAEAALDEDAQRKGLKVSDEEIGRQIKSDPNFKGANNAFDAARFAGLIRQLGYTEQRYVAEQRN
MALRRQIVGTMTAGVEPSKTLLEALNRFQNEQRTIDYVKLGAAQAGTIDPPTADQLSGYFDAHKVQFRAPEYRKVAFVVL
TPEEVAKWTAVSDDDARKIYEERKDKLSTPERRQLRQIMFPSVTDAQAAREKIAGGASFDDIARERGLATSDIDLGTISK
AEIIDPAIANAAFSINSDEVSQPTQGRFGVALIKVGRIEPGNQPTYESVAEKLKRDVALDRARAEINNLHNKMEDERGGG
ASVVEAAKKVGLSAVTIEATDRSGRAPDGKPVSGIPQGVDLIAQAFASDVGVDNDTLQLGNNGFIWFDVIGVTPSRDRTL
DEVKDKVEARWREDQISSRLMTKATDTIRKLEQGGKLADEAASLGLKVESASAIKRDATTTALPAAVVAAVCRAAKDAAG
QAPGAGNDEWFIFRVTDVKVPTLDLASDETKKLREGVQRGLSDEYIGQYIVKLEAEIGTKINQAAVAQITGASSNF
>Mature_636_residues
MLRGIRNASSNWLGKTLMTIVMGLLIVAFGIWGIADIFHGFGQSALATVGGTEISTEQFRQIYNDRLQQIGRQFGRPLPP
DQVRALGLDRQILQQVIAEAALDEDAQRKGLKVSDEEIGRQIKSDPNFKGANNAFDAARFAGLIRQLGYTEQRYVAEQRN
MALRRQIVGTMTAGVEPSKTLLEALNRFQNEQRTIDYVKLGAAQAGTIDPPTADQLSGYFDAHKVQFRAPEYRKVAFVVL
TPEEVAKWTAVSDDDARKIYEERKDKLSTPERRQLRQIMFPSVTDAQAAREKIAGGASFDDIARERGLATSDIDLGTISK
AEIIDPAIANAAFSINSDEVSQPTQGRFGVALIKVGRIEPGNQPTYESVAEKLKRDVALDRARAEINNLHNKMEDERGGG
ASVVEAAKKVGLSAVTIEATDRSGRAPDGKPVSGIPQGVDLIAQAFASDVGVDNDTLQLGNNGFIWFDVIGVTPSRDRTL
DEVKDKVEARWREDQISSRLMTKATDTIRKLEQGGKLADEAASLGLKVESASAIKRDATTTALPAAVVAAVCRAAKDAAG
QAPGAGNDEWFIFRVTDVKVPTLDLASDETKKLREGVQRGLSDEYIGQYIVKLEAEIGTKINQAAVAQITGASSNF

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=621, Percent_Identity=25.2818035426731, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69143; Mature: 69143

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRGIRNASSNWLGKTLMTIVMGLLIVAFGIWGIADIFHGFGQSALATVGGTEISTEQFR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHH
QIYNDRLQQIGRQFGRPLPPDQVRALGLDRQILQQVIAEAALDEDAQRKGLKVSDEEIGR
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHH
QIKSDPNFKGANNAFDAARFAGLIRQLGYTEQRYVAEQRNMALRRQIVGTMTAGVEPSKT
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LLEALNRFQNEQRTIDYVKLGAAQAGTIDPPTADQLSGYFDAHKVQFRAPEYRKVAFVVL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCHHHHHEEEECCCCCCEEEEEEE
TPEEVAKWTAVSDDDARKIYEERKDKLSTPERRQLRQIMFPSVTDAQAAREKIAGGASFD
CHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCHH
DIARERGLATSDIDLGTISKAEIIDPAIANAAFSINSDEVSQPTQGRFGVALIKVGRIEP
HHHHHCCCCCCCCCCCCCCHHHHCCHHHHHCEEECCCHHCCCCCCCCCCEEEEEECCCCC
GNQPTYESVAEKLKRDVALDRARAEINNLHNKMEDERGGGASVVEAAKKVGLSAVTIEAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEC
DRSGRAPDGKPVSGIPQGVDLIAQAFASDVGVDNDTLQLGNNGFIWFDVIGVTPSRDRTL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCCCCCCHH
DEVKDKVEARWREDQISSRLMTKATDTIRKLEQGGKLADEAASLGLKVESASAIKRDATT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEECCHHHHHHCCHH
TALPAAVVAAVCRAAKDAAGQAPGAGNDEWFIFRVTDVKVPTLDLASDETKKLREGVQRG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHC
LSDEYIGQYIVKLEAEIGTKINQAAVAQITGASSNF
CCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLRGIRNASSNWLGKTLMTIVMGLLIVAFGIWGIADIFHGFGQSALATVGGTEISTEQFR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHH
QIYNDRLQQIGRQFGRPLPPDQVRALGLDRQILQQVIAEAALDEDAQRKGLKVSDEEIGR
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHH
QIKSDPNFKGANNAFDAARFAGLIRQLGYTEQRYVAEQRNMALRRQIVGTMTAGVEPSKT
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LLEALNRFQNEQRTIDYVKLGAAQAGTIDPPTADQLSGYFDAHKVQFRAPEYRKVAFVVL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCHHHHHEEEECCCCCCEEEEEEE
TPEEVAKWTAVSDDDARKIYEERKDKLSTPERRQLRQIMFPSVTDAQAAREKIAGGASFD
CHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCHH
DIARERGLATSDIDLGTISKAEIIDPAIANAAFSINSDEVSQPTQGRFGVALIKVGRIEP
HHHHHCCCCCCCCCCCCCCHHHHCCHHHHHCEEECCCHHCCCCCCCCCCEEEEEECCCCC
GNQPTYESVAEKLKRDVALDRARAEINNLHNKMEDERGGGASVVEAAKKVGLSAVTIEAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEC
DRSGRAPDGKPVSGIPQGVDLIAQAFASDVGVDNDTLQLGNNGFIWFDVIGVTPSRDRTL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCCCCCCHH
DEVKDKVEARWREDQISSRLMTKATDTIRKLEQGGKLADEAASLGLKVESASAIKRDATT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEECCHHHHHHCCHH
TALPAAVVAAVCRAAKDAAGQAPGAGNDEWFIFRVTDVKVPTLDLASDETKKLREGVQRG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHC
LSDEYIGQYIVKLEAEIGTKINQAAVAQITGASSNF
CCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]