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The map label for this gene is mraY [H]

Identifier: 75675241

GI number: 75675241

Start: 1142425

End: 1143531

Strand: Direct

Name: mraY [H]

Synonym: Nwi_1048

Alternate gene names: 75675241

Gene position: 1142425-1143531 (Clockwise)

Preceding gene: 75675240

Following gene: 75675242

Centisome position: 33.58

GC content: 63.05

Gene sequence:

>1107_bases
ATGTTTTACTGGTTGATCGATCTTTCCAATACGGTCCCGGGGCTCGGCATCTTCAAGCCGCTTCTGAACGTCTTTCGCTA
CATCACCTTCCGCACCGGCGGCGCGGTGGTGACGGGCGCGCTGTTCGTGTTCCTGTTCGGGCCCTGGATCATCGACAATC
TTCGCCTGCGACAGGGTAAAGGACAACCGATCCGCGCCGACGGCCCGCAGTCGCACCTCGTCAGCAAGAAGGGCACGCCG
ACGATGGGGGGCCTGATGATTCTGTCGGGGCTTGTCGTGTCGACCGTGCTGTGGGCCAATCCTCTCAATCCCTATGTCTG
GATCGTGCTCGCGGTGACGCTTGGTTTCGGCCTCATCGGCTTCTATGACGACTATCTGAAGGTGACGAAGCAGACCCATG
CCGGATTCTCCGGACGCACCCGCCTGCTGCTTGAACTCCTGATCGCGCTGGCCGCGTGCTATGCGCTGACCCGGCTCGGC
CGCGAGCCCTTCTCCACGGCGCTGGTGATCCCGTTCTTCAAGGACGTGGCGCTGGATCTCGGCTGGTTCTTTCTCGGCTT
TGGCGCGTTCATCATCGTCGGAGCCGGCAACGCGGTGAATCTCACCGACGGCCTCGACGGTCTCGCCATCGTGCCGGTCA
TGATCGCGGCGGCGAGCTTCGCGATGATCGCCTATCTCGCCGGCAACGCGGTGTTCGCCGACTATCTCCAGATCAACTAC
ATCGCCGGCGCGGGCGAACTGGCTGTGCTGTGCGGGGCAGTGCTCGGGGCCGGCCTCGGTTTTCTCTGGTTCAACGCCCC
GCCGGCCTCGATCTTCATGGGCGACACCGGTTCGCTCGCGCTCGGCGGCATGCTCGGCTCGATCGCGGTGGCGGTGAAGC
ATGAAATCGTGCTGGCCGTGATCGGCGGCCTGTTCGTGCTGGAAGCGGTGTCGGTGATCGTGCAGGTGGCGTCGTTCAAG
CTCACGGGAAAGCGCATCTTCAAGATGGCGCCGATCCACCACCACTTCGAGCAGCTCGGCTGGACCGAGCCGCAGATCGT
GATCAGGTTCTGGATCATTTCGGTGATGCTGGCGCTGGCGGGTCTTTCGACGCTGAAGTTGCGGTGA

Upstream 100 bases:

>100_bases
CGCGGCTGAAATTCTGTAAGTTGCGGGGTGCCCCTTTGAATCCGGAGTTCGCTCAAGGGAGGCTTGCCAGAACTGGCGAA
CTTCGGAGTCGGGATACCCG

Downstream 100 bases:

>100_bases
TGAAGCCCCCATGATCCCCGTCACATCCTTTTCCGGCAAGACCGTCGCGGTATTTGGCCTCGGCGGTTCGGGCCTTGCGA
GTTGTCACGCCCTGAAGGCG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MFYWLIDLSNTVPGLGIFKPLLNVFRYITFRTGGAVVTGALFVFLFGPWIIDNLRLRQGKGQPIRADGPQSHLVSKKGTP
TMGGLMILSGLVVSTVLWANPLNPYVWIVLAVTLGFGLIGFYDDYLKVTKQTHAGFSGRTRLLLELLIALAACYALTRLG
REPFSTALVIPFFKDVALDLGWFFLGFGAFIIVGAGNAVNLTDGLDGLAIVPVMIAAASFAMIAYLAGNAVFADYLQINY
IAGAGELAVLCGAVLGAGLGFLWFNAPPASIFMGDTGSLALGGMLGSIAVAVKHEIVLAVIGGLFVLEAVSVIVQVASFK
LTGKRIFKMAPIHHHFEQLGWTEPQIVIRFWIISVMLALAGLSTLKLR

Sequences:

>Translated_368_residues
MFYWLIDLSNTVPGLGIFKPLLNVFRYITFRTGGAVVTGALFVFLFGPWIIDNLRLRQGKGQPIRADGPQSHLVSKKGTP
TMGGLMILSGLVVSTVLWANPLNPYVWIVLAVTLGFGLIGFYDDYLKVTKQTHAGFSGRTRLLLELLIALAACYALTRLG
REPFSTALVIPFFKDVALDLGWFFLGFGAFIIVGAGNAVNLTDGLDGLAIVPVMIAAASFAMIAYLAGNAVFADYLQINY
IAGAGELAVLCGAVLGAGLGFLWFNAPPASIFMGDTGSLALGGMLGSIAVAVKHEIVLAVIGGLFVLEAVSVIVQVASFK
LTGKRIFKMAPIHHHFEQLGWTEPQIVIRFWIISVMLALAGLSTLKLR
>Mature_368_residues
MFYWLIDLSNTVPGLGIFKPLLNVFRYITFRTGGAVVTGALFVFLFGPWIIDNLRLRQGKGQPIRADGPQSHLVSKKGTP
TMGGLMILSGLVVSTVLWANPLNPYVWIVLAVTLGFGLIGFYDDYLKVTKQTHAGFSGRTRLLLELLIALAACYALTRLG
REPFSTALVIPFFKDVALDLGWFFLGFGAFIIVGAGNAVNLTDGLDGLAIVPVMIAAASFAMIAYLAGNAVFADYLQINY
IAGAGELAVLCGAVLGAGLGFLWFNAPPASIFMGDTGSLALGGMLGSIAVAVKHEIVLAVIGGLFVLEAVSVIVQVASFK
LTGKRIFKMAPIHHHFEQLGWTEPQIVIRFWIISVMLALAGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=346, Percent_Identity=54.6242774566474, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39452; Mature: 39452

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYWLIDLSNTVPGLGIFKPLLNVFRYITFRTGGAVVTGALFVFLFGPWIIDNLRLRQGK
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEECCC
GQPIRADGPQSHLVSKKGTPTMGGLMILSGLVVSTVLWANPLNPYVWIVLAVTLGFGLIG
CCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FYDDYLKVTKQTHAGFSGRTRLLLELLIALAACYALTRLGREPFSTALVIPFFKDVALDL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHH
GWFFLGFGAFIIVGAGNAVNLTDGLDGLAIVPVMIAAASFAMIAYLAGNAVFADYLQINY
HHHHHHHHHEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEEE
IAGAGELAVLCGAVLGAGLGFLWFNAPPASIFMGDTGSLALGGMLGSIAVAVKHEIVLAV
ECCCCHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
IGGLFVLEAVSVIVQVASFKLTGKRIFKMAPIHHHFEQLGWTEPQIVIRFWIISVMLALA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GLSTLKLR
CCHHHCCC
>Mature Secondary Structure
MFYWLIDLSNTVPGLGIFKPLLNVFRYITFRTGGAVVTGALFVFLFGPWIIDNLRLRQGK
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEECCC
GQPIRADGPQSHLVSKKGTPTMGGLMILSGLVVSTVLWANPLNPYVWIVLAVTLGFGLIG
CCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FYDDYLKVTKQTHAGFSGRTRLLLELLIALAACYALTRLGREPFSTALVIPFFKDVALDL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHH
GWFFLGFGAFIIVGAGNAVNLTDGLDGLAIVPVMIAAASFAMIAYLAGNAVFADYLQINY
HHHHHHHHHEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEEE
IAGAGELAVLCGAVLGAGLGFLWFNAPPASIFMGDTGSLALGGMLGSIAVAVKHEIVLAV
ECCCCHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
IGGLFVLEAVSVIVQVASFKLTGKRIFKMAPIHHHFEQLGWTEPQIVIRFWIISVMLALA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GLSTLKLR
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA