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The map label for this gene is lpsI [H]

Identifier: 75675203

GI number: 75675203

Start: 1106113

End: 1107102

Strand: Direct

Name: lpsI [H]

Synonym: Nwi_1010

Alternate gene names: 75675203

Gene position: 1106113-1107102 (Clockwise)

Preceding gene: 75675201

Following gene: 75675204

Centisome position: 32.51

GC content: 60.81

Gene sequence:

>990_bases
GTGACGCCTGCCGGTTCCGCGCTGTCCGGCGGCGCGCGCAACTTGATTGGTTTTCTTGACGCTTTCAAGGCCGCCGATCG
TTCGATTTTGACATTTGCGGGCCGCCACGGCGCGTTTGATCTTCGCAGCCAGATCGCTGCACCGAGGCCAGCGATTGTCA
AATTCGCGTCGCCAGGATCGGATAAGCCTCCAATTGACGCCCCGCGCGTATTTTGCCTAACTACTTCTCGTTCTGCCCGC
GCCGGCAAGCGGCGCCATTCTCCATGCAGGTCGCAACTCATGAAAAAGGTCTACCCTGACGCCAAATCGGCCCTCGACGG
CCTTCTCAGGGACGGCATGATGATCATGTCAGGCGGATTCGGCTTGTGCGGCATCCCGGAAACGCTGTCCGAGGCCATTC
GTGACTCGGGAGTCAAGGATCTGACATTCGTGTCCAATAACGCCGGCGTCGATGGCATCGGACTGAGTCGCTTGCTCGAA
ACGCGGCAAATCAGGAAGATGATTTCGTCCTATGTCGGTGAGAACAAGCTTTTCGCCCAGCAGTATCTCGCCGGCGATCT
GGAGCTTGAATTCAATCCACAGGGCACGCTGGCCGAGCGCATTCGCGCGGGCGGCGCCGGCATTCCGGCATTCTACACCA
AGACCGGCGTCGGCACGCTCATTGCCGAGGGCAAGGAGGTGAAGGAATTCGACGGCCAGAAGTACCTCATGGAGCGAGGA
CTGTTCGCCGATCTCGCCATCGTTCACGCCTGGAAGGGCGACACCGCCGGCAATCTGGTCTATCGCAAGACCGCGCGAAA
CTTCAATCCGATGATGGCGACCGCCGCGAAGGTGACCGTCGCGGAAGTCGAACATCTGGTGCCTGCCGGCGAGATCGATC
CCGATCACGTCCACACCCCCGGCATCTTCGTCAAGCGCATCGTCGAGGTCGGCGGCGCCAGGAAGCACATCGAGTTCCGT
AATACCCGTCCACGCCCGGCGGCGGCATGA

Upstream 100 bases:

>100_bases
TCACCGCAACTCCCAGAATGGCCGCGACCGATATTCCCAGGCGCTTCATTCCTTGGGCCATCGTCCTTGGGTCATCGTCA
ATCAACATGTCCGGGATGGG

Downstream 100 bases:

>100_bases
TCCGGAAAAGCACCAAGCTCCTTGCAATGATGACAAGGTGACAGGAGAGCCTCATGGCCTGGACCCGCGAGCAGATGGCG
GCGCGCGCCGCCAAGGAATT

Product: coenzyme A transferase

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTPAGSALSGGARNLIGFLDAFKAADRSILTFAGRHGAFDLRSQIAAPRPAIVKFASPGSDKPPIDAPRVFCLTTSRSAR
AGKRRHSPCRSQLMKKVYPDAKSALDGLLRDGMMIMSGGFGLCGIPETLSEAIRDSGVKDLTFVSNNAGVDGIGLSRLLE
TRQIRKMISSYVGENKLFAQQYLAGDLELEFNPQGTLAERIRAGGAGIPAFYTKTGVGTLIAEGKEVKEFDGQKYLMERG
LFADLAIVHAWKGDTAGNLVYRKTARNFNPMMATAAKVTVAEVEHLVPAGEIDPDHVHTPGIFVKRIVEVGGARKHIEFR
NTRPRPAAA

Sequences:

>Translated_329_residues
MTPAGSALSGGARNLIGFLDAFKAADRSILTFAGRHGAFDLRSQIAAPRPAIVKFASPGSDKPPIDAPRVFCLTTSRSAR
AGKRRHSPCRSQLMKKVYPDAKSALDGLLRDGMMIMSGGFGLCGIPETLSEAIRDSGVKDLTFVSNNAGVDGIGLSRLLE
TRQIRKMISSYVGENKLFAQQYLAGDLELEFNPQGTLAERIRAGGAGIPAFYTKTGVGTLIAEGKEVKEFDGQKYLMERG
LFADLAIVHAWKGDTAGNLVYRKTARNFNPMMATAAKVTVAEVEHLVPAGEIDPDHVHTPGIFVKRIVEVGGARKHIEFR
NTRPRPAAA
>Mature_328_residues
TPAGSALSGGARNLIGFLDAFKAADRSILTFAGRHGAFDLRSQIAAPRPAIVKFASPGSDKPPIDAPRVFCLTTSRSARA
GKRRHSPCRSQLMKKVYPDAKSALDGLLRDGMMIMSGGFGLCGIPETLSEAIRDSGVKDLTFVSNNAGVDGIGLSRLLET
RQIRKMISSYVGENKLFAQQYLAGDLELEFNPQGTLAERIRAGGAGIPAFYTKTGVGTLIAEGKEVKEFDGQKYLMERGL
FADLAIVHAWKGDTAGNLVYRKTARNFNPMMATAAKVTVAEVEHLVPAGEIDPDHVHTPGIFVKRIVEVGGARKHIEFRN
TRPRPAAA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=246, Percent_Identity=50.4065040650407, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI11545841, Length=245, Percent_Identity=49.7959183673469, Blast_Score=227, Evalue=1e-59,
Organism=Escherichia coli, GI1788551, Length=202, Percent_Identity=45.5445544554455, Blast_Score=193, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=248, Percent_Identity=50.8064516129032, Blast_Score=242, Evalue=2e-64,
Organism=Drosophila melanogaster, GI21358325, Length=277, Percent_Identity=47.6534296028881, Blast_Score=246, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24655794, Length=277, Percent_Identity=47.6534296028881, Blast_Score=246, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 35394; Mature: 35263

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAGSALSGGARNLIGFLDAFKAADRSILTFAGRHGAFDLRSQIAAPRPAIVKFASPGS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCEEEECCCCC
DKPPIDAPRVFCLTTSRSARAGKRRHSPCRSQLMKKVYPDAKSALDGLLRDGMMIMSGGF
CCCCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCC
GLCGIPETLSEAIRDSGVKDLTFVSNNAGVDGIGLSRLLETRQIRKMISSYVGENKLFAQ
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QYLAGDLELEFNPQGTLAERIRAGGAGIPAFYTKTGVGTLIAEGKEVKEFDGQKYLMERG
HHHCCCEEEEECCCCHHHHHHHCCCCCCCHHHHHCCCHHHHHCCCHHHHHCCHHHHHHCC
LFADLAIVHAWKGDTAGNLVYRKTARNFNPMMATAAKVTVAEVEHLVPAGEIDPDHVHTP
CHHHHHHEEEECCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GIFVKRIVEVGGARKHIEFRNTRPRPAAA
HHHHHHHHHHCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TPAGSALSGGARNLIGFLDAFKAADRSILTFAGRHGAFDLRSQIAAPRPAIVKFASPGS
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCEEEECCCCC
DKPPIDAPRVFCLTTSRSARAGKRRHSPCRSQLMKKVYPDAKSALDGLLRDGMMIMSGGF
CCCCCCCCEEEEEECCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCC
GLCGIPETLSEAIRDSGVKDLTFVSNNAGVDGIGLSRLLETRQIRKMISSYVGENKLFAQ
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QYLAGDLELEFNPQGTLAERIRAGGAGIPAFYTKTGVGTLIAEGKEVKEFDGQKYLMERG
HHHCCCEEEEECCCCHHHHHHHCCCCCCCHHHHHCCCHHHHHCCCHHHHHCCHHHHHHCC
LFADLAIVHAWKGDTAGNLVYRKTARNFNPMMATAAKVTVAEVEHLVPAGEIDPDHVHTP
CHHHHHHEEEECCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GIFVKRIVEVGGARKHIEFRNTRPRPAAA
HHHHHHHHHHCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]