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The map label for this gene is dksA [H]

Identifier: 74318551

GI number: 74318551

Start: 2605056

End: 2605475

Strand: Direct

Name: dksA [H]

Synonym: Tbd_2533

Alternate gene names: 74318551

Gene position: 2605056-2605475 (Clockwise)

Preceding gene: 74318546

Following gene: 74318552

Centisome position: 89.53

GC content: 64.76

Gene sequence:

>420_bases
ATGCCCAGTTCGTCGAAGCCCCTCACTGAAGCCGCCCTGCTGAAGATGCCTGCGTCCGCCTACATGAACGCCGCGCAACT
GGCATTCTTCCGCGAGCGGCTCGAAGCCCTGCGTGACGAGATGCTGAGCAACGCCGCCGACACCGGCGAGCACCTCAAGG
AAAACGAGAATTTCGCCGACCCCAACGACCGCGCGACGGTCGAGGAAGAGCACATGCTCGAGCAGCGCGTGCGCGACCGC
GAACGCAAGCTGCTGAAAAAGATCAACAGCGCGCTCACCCGCATCGAAACCGGCGAATACGGCTGGTGCCTTGAGACCGG
CGATCCGATCGGGCTGCCGCGCCTGCTCGCCCGGCCGACCGCCGAGTACTCGATCGAAGCGCAGGAGCGGCACGAACGCA
AGGAAAAGCTGCACGCCTGA

Upstream 100 bases:

>100_bases
GTTATGATGCGGGACGCATCGCGTGGCAACCGGCTTCCGGTTGTCGGCCGGATCCCTATTTGGCCCTGCTTTAACCTTTA
TATCCGTACGGAGTTGTCCC

Downstream 100 bases:

>100_bases
CGCGCGCCCCTCTCGTCCGGGCGCCGTTCAGGCCGGCGCTCGGCCGCCCCGCCGACATCCGCTTCCGCCGTGATCCCGCC
AGAACCCATTCCCGTCACCC

Product: TraR/DksA family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MPSSSKPLTEAALLKMPASAYMNAAQLAFFRERLEALRDEMLSNAADTGEHLKENENFADPNDRATVEEEHMLEQRVRDR
ERKLLKKINSALTRIETGEYGWCLETGDPIGLPRLLARPTAEYSIEAQERHERKEKLHA

Sequences:

>Translated_139_residues
MPSSSKPLTEAALLKMPASAYMNAAQLAFFRERLEALRDEMLSNAADTGEHLKENENFADPNDRATVEEEHMLEQRVRDR
ERKLLKKINSALTRIETGEYGWCLETGDPIGLPRLLARPTAEYSIEAQERHERKEKLHA
>Mature_138_residues
PSSSKPLTEAALLKMPASAYMNAAQLAFFRERLEALRDEMLSNAADTGEHLKENENFADPNDRATVEEEHMLEQRVRDRE
RKLLKKINSALTRIETGEYGWCLETGDPIGLPRLLARPTAEYSIEAQERHERKEKLHA

Specific function: Dosage-Dependent Suppressor Of A Dnak Deletion Mutation. It Suppressed Not Only The Temperature-Sensitive Growth But Also The Filamentous Phenotype Of The Dnak Deletion Strain, While The Defect Of Lambda Growth Is Not Suppressed. [C]

COG id: COG1734

COG function: function code T; DnaK suppressor protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 dksA C4-type zinc finger [H]

Homologues:

Organism=Escherichia coli, GI1786338, Length=124, Percent_Identity=47.5806451612903, Blast_Score=103, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012784
- InterPro:   IPR000962
- InterPro:   IPR020458 [H]

Pfam domain/function: PF01258 zf-dskA_traR [H]

EC number: NA

Molecular weight: Translated: 15906; Mature: 15775

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS51128 ZF_DKSA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSSKPLTEAALLKMPASAYMNAAQLAFFRERLEALRDEMLSNAADTGEHLKENENFAD
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PNDRATVEEEHMLEQRVRDRERKLLKKINSALTRIETGEYGWCLETGDPIGLPRLLARPT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHCCC
AEYSIEAQERHERKEKLHA
CHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
PSSSKPLTEAALLKMPASAYMNAAQLAFFRERLEALRDEMLSNAADTGEHLKENENFAD
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PNDRATVEEEHMLEQRVRDRERKLLKKINSALTRIETGEYGWCLETGDPIGLPRLLARPT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHCCC
AEYSIEAQERHERKEKLHA
CHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9555902 [H]