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The map label for this gene is xerC [H]

Identifier: 74318546

GI number: 74318546

Start: 2598405

End: 2599289

Strand: Direct

Name: xerC [H]

Synonym: Tbd_2528

Alternate gene names: 74318546

Gene position: 2598405-2599289 (Clockwise)

Preceding gene: 74318545

Following gene: 74318551

Centisome position: 89.3

GC content: 70.17

Gene sequence:

>885_bases
TTGAATCCTTTCGCACCCTATCTGCAACACCTCGCCGCCGAAAGGCGGCTGTCTGCCCACACGCTTTCCGCCTACGCGCG
CGACCTCGAAAACCTCGCCCGGCTGACCGACGGCAAGCCACTCGACACGCTGACGAGCCACGACATTCGCGGCGCCATCG
TGAAGCTGCGTGCCGGCGGCCTGGCCGCGGCGAGCGTCGCGCGTCAACTGTCGAGCTGGCGCGGCTTTTACGCCTTCGCG
TGCCGGCGGCTCGGCTACCCCGACAACCCTTGCGCCGGCCTGCGTCCGCCGAAGGCGTCGCGCGCGCTGCCGGACATTCT
TTCGCCGGACGCCTGCGCGCGGCTTCTCGACGCACCCGACGGCGACGAGGATCTGCTCGCGACGCGCGACCGGGCGATGT
TCGAACTGTTTTATTCGTCCGGCCTGCGCCTGTCCGAACTCGTCGGCATCGATCTGCCCGACCTCGACCTCGCGAGCGGC
GAGGCCCGCGTGACCGGCAAGGGCAAGAAGACACGGCTGGTCCCGGTCGGCCGGCAGGCGGTCGCGGCGATCACCGCCTG
GCTACCGTTGCGGCTCACGCTCGTGCGCACGCCGACCGAGGCGCTTTTCGTCGGCCAGCGCGGGGCGCGCCTCACCCCGC
GCAACGTGCAATTGCGGCTCGCGCGTTGGGCGCGCGCGTCGGGCCTCGGCCAGCACGTCCATCCGCACATGCTCCGCCAC
GCGTTCGCCACGCACGTCCTGCAGTCCTCGGGCGATCTGCGCGCGGTGCAGGAAATGCTCGGCCACGCGAGCATCAGCAC
GACCCAGGTCTATACCCATCTCGACTGGCAGCACCTCGCCAAGGCCTACGACCAGGCGCATCCGCGCGCGCGCAAGAAGG
ACTGA

Upstream 100 bases:

>100_bases
TCGCCTCCGAGGAAGCGCGCCGCTTCTACCCGGGCATGGGCACGCTCTATCTCGAACGACTCGGACAGATGCTCGGCGCC
GCGCTGGTGCGGATGCAGGA

Downstream 100 bases:

>100_bases
GGAAGCCGACTCGAGCGCCCGCGCCCCGCGACGGCAGCGAGACGGGCGGCCGAGCGGAGCCCGGTCGAATCAGATGATCG
GTGTCCCGGCAACGCCGGCG

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MNPFAPYLQHLAAERRLSAHTLSAYARDLENLARLTDGKPLDTLTSHDIRGAIVKLRAGGLAAASVARQLSSWRGFYAFA
CRRLGYPDNPCAGLRPPKASRALPDILSPDACARLLDAPDGDEDLLATRDRAMFELFYSSGLRLSELVGIDLPDLDLASG
EARVTGKGKKTRLVPVGRQAVAAITAWLPLRLTLVRTPTEALFVGQRGARLTPRNVQLRLARWARASGLGQHVHPHMLRH
AFATHVLQSSGDLRAVQEMLGHASISTTQVYTHLDWQHLAKAYDQAHPRARKKD

Sequences:

>Translated_294_residues
MNPFAPYLQHLAAERRLSAHTLSAYARDLENLARLTDGKPLDTLTSHDIRGAIVKLRAGGLAAASVARQLSSWRGFYAFA
CRRLGYPDNPCAGLRPPKASRALPDILSPDACARLLDAPDGDEDLLATRDRAMFELFYSSGLRLSELVGIDLPDLDLASG
EARVTGKGKKTRLVPVGRQAVAAITAWLPLRLTLVRTPTEALFVGQRGARLTPRNVQLRLARWARASGLGQHVHPHMLRH
AFATHVLQSSGDLRAVQEMLGHASISTTQVYTHLDWQHLAKAYDQAHPRARKKD
>Mature_294_residues
MNPFAPYLQHLAAERRLSAHTLSAYARDLENLARLTDGKPLDTLTSHDIRGAIVKLRAGGLAAASVARQLSSWRGFYAFA
CRRLGYPDNPCAGLRPPKASRALPDILSPDACARLLDAPDGDEDLLATRDRAMFELFYSSGLRLSELVGIDLPDLDLASG
EARVTGKGKKTRLVPVGRQAVAAITAWLPLRLTLVRTPTEALFVGQRGARLTPRNVQLRLARWARASGLGQHVHPHMLRH
AFATHVLQSSGDLRAVQEMLGHASISTTQVYTHLDWQHLAKAYDQAHPRARKKD

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=289, Percent_Identity=50.5190311418685, Blast_Score=269, Evalue=1e-73,
Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=40.2061855670103, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI1790768, Length=147, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790767, Length=196, Percent_Identity=26.530612244898, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32304; Mature: 32304

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFAPYLQHLAAERRLSAHTLSAYARDLENLARLTDGKPLDTLTSHDIRGAIVKLRAGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHEEEEEECCC
LAAASVARQLSSWRGFYAFACRRLGYPDNPCAGLRPPKASRALPDILSPDACARLLDAPD
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHCCHHHHHHHHCCCC
GDEDLLATRDRAMFELFYSSGLRLSELVGIDLPDLDLASGEARVTGKGKKTRLVPVGRQA
CCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEECCHHH
VAAITAWLPLRLTLVRTPTEALFVGQRGARLTPRNVQLRLARWARASGLGQHVHPHMLRH
HHHHHHHHHHEEEEEECCHHHEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
AFATHVLQSSGDLRAVQEMLGHASISTTQVYTHLDWQHLAKAYDQAHPRARKKD
HHHHHHHHCCCCHHHHHHHHCCCCCCHHHHEECCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNPFAPYLQHLAAERRLSAHTLSAYARDLENLARLTDGKPLDTLTSHDIRGAIVKLRAGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHEEEEEECCC
LAAASVARQLSSWRGFYAFACRRLGYPDNPCAGLRPPKASRALPDILSPDACARLLDAPD
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHCCHHHHHHHHCCCC
GDEDLLATRDRAMFELFYSSGLRLSELVGIDLPDLDLASGEARVTGKGKKTRLVPVGRQA
CCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEECCHHH
VAAITAWLPLRLTLVRTPTEALFVGQRGARLTPRNVQLRLARWARASGLGQHVHPHMLRH
HHHHHHHHHHEEEEEECCHHHEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
AFATHVLQSSGDLRAVQEMLGHASISTTQVYTHLDWQHLAKAYDQAHPRARKKD
HHHHHHHHCCCCHHHHHHHHCCCCCCHHHHEECCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA