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The map label for this gene is xerD [H]

Identifier: 74318396

GI number: 74318396

Start: 2451958

End: 2452848

Strand: Direct

Name: xerD [H]

Synonym: Tbd_2378

Alternate gene names: 74318396

Gene position: 2451958-2452848 (Clockwise)

Preceding gene: 74318395

Following gene: 74318400

Centisome position: 84.27

GC content: 67.56

Gene sequence:

>891_bases
ATGAACGACGCGCTGATTGATCGTTTCTGCGACCACCTGTGGCTGGAGGACGGGCTCGCCGAACTGACCCTGGCTGCGTA
CCGGCGCGACCTCAGAAGCTTTGCCGGGTGGCTGGACAAAACGCGCGCGCGCTCGCTCGACGCGGTCGCGCCCGGAGATG
TCGAAGCCTATCTCGGGTGGCGCTTCGCCCACCACGTCGGGCCACGCAGCGCAGCGCGTTATACCTCCGCGCTCAAGCGT
TTCTATCGTTACCTGCTCCGCGAAAACCTAATCGCCGCCGACCCGACGCTGAACCTCGACCGCCCGAAACTGCCGCGCGC
GCTTCCCGCCAGCCTGAGCGAAACCGACGTCGAACGCCTGCTCGAGCGCGCGGACAGCGACACGCCGCAGGGCCTGCGCG
ACCGGGCGATGCTCGAGACGCTATATGCTACGGGGCTCAGGGTGTCCGAACTCGTCGGCTTGAAGTTGAACGCGCTCAAC
CTCGACGACGGTGTATTGCGCGTGACGGGCAAGGGCAACAAGGACCGGCTGGTGCCGCTCGGTGAAGAGGCCGTGCGCCG
GCTTCGGCACTATCTCGCCGAGGCGCGCTCGCAGCTCCTGCGCCGCCAGGTCTCCGACGCCGTGTTCGTCACCCCTCGCG
GCGCCGCGATGACCCGGCAAGCCTTCTGGTACCTGATCAAGCGGCGCGCAGCGGCAGCCGGCGTCACGCGTCAGCTGTCG
CCGCACACGCTGCGCCACGCCTTCGCTACCCATCTTCTCAATCACGGTGCCGACCTGCGCGTCGTGCAGATGTTGCTCGG
ACACAGCGACATCTCGACCACTCAGATCTACACCCACGTCGCGCGCGAGCGGATGAAGCGCCTGCACGCCGCGCACCATC
CGCGCGGCTAG

Upstream 100 bases:

>100_bases
CTGATTCCCTGCCATCGCGTCGTTGCCGCGCGCGGCGTCGGCGGATTCATGCACGCCGACTCGGGAATGCCGCTGGACGT
GAAGCTCTCGCTGCTGGCCC

Downstream 100 bases:

>100_bases
CGTTACACGCGGCCGCTCGCCTCCGCGAGGTAGAACCACTCCTGTCCGGGCAAGGCGCCCGGATTGGGAAAAACGACATA
GCCTTCTCGGTCGGCGCGAA

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNDALIDRFCDHLWLEDGLAELTLAAYRRDLRSFAGWLDKTRARSLDAVAPGDVEAYLGWRFAHHVGPRSAARYTSALKR
FYRYLLRENLIAADPTLNLDRPKLPRALPASLSETDVERLLERADSDTPQGLRDRAMLETLYATGLRVSELVGLKLNALN
LDDGVLRVTGKGNKDRLVPLGEEAVRRLRHYLAEARSQLLRRQVSDAVFVTPRGAAMTRQAFWYLIKRRAAAAGVTRQLS
PHTLRHAFATHLLNHGADLRVVQMLLGHSDISTTQIYTHVARERMKRLHAAHHPRG

Sequences:

>Translated_296_residues
MNDALIDRFCDHLWLEDGLAELTLAAYRRDLRSFAGWLDKTRARSLDAVAPGDVEAYLGWRFAHHVGPRSAARYTSALKR
FYRYLLRENLIAADPTLNLDRPKLPRALPASLSETDVERLLERADSDTPQGLRDRAMLETLYATGLRVSELVGLKLNALN
LDDGVLRVTGKGNKDRLVPLGEEAVRRLRHYLAEARSQLLRRQVSDAVFVTPRGAAMTRQAFWYLIKRRAAAAGVTRQLS
PHTLRHAFATHLLNHGADLRVVQMLLGHSDISTTQIYTHVARERMKRLHAAHHPRG
>Mature_296_residues
MNDALIDRFCDHLWLEDGLAELTLAAYRRDLRSFAGWLDKTRARSLDAVAPGDVEAYLGWRFAHHVGPRSAARYTSALKR
FYRYLLRENLIAADPTLNLDRPKLPRALPASLSETDVERLLERADSDTPQGLRDRAMLETLYATGLRVSELVGLKLNALN
LDDGVLRVTGKGNKDRLVPLGEEAVRRLRHYLAEARSQLLRRQVSDAVFVTPRGAAMTRQAFWYLIKRRAAAAGVTRQLS
PHTLRHAFATHLLNHGADLRVVQMLLGHSDISTTQIYTHVARERMKRLHAAHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=56.4625850340136, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1790244, Length=290, Percent_Identity=35.8620689655172, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1790767, Length=168, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790768, Length=152, Percent_Identity=34.2105263157895, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33487; Mature: 33487

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDALIDRFCDHLWLEDGLAELTLAAYRRDLRSFAGWLDKTRARSLDAVAPGDVEAYLGW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RFAHHVGPRSAARYTSALKRFYRYLLRENLIAADPTLNLDRPKLPRALPASLSETDVERL
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LERADSDTPQGLRDRAMLETLYATGLRVSELVGLKLNALNLDDGVLRVTGKGNKDRLVPL
HHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCCC
GEEAVRRLRHYLAEARSQLLRRQVSDAVFVTPRGAAMTRQAFWYLIKRRAAAAGVTRQLS
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PHTLRHAFATHLLNHGADLRVVQMLLGHSDISTTQIYTHVARERMKRLHAAHHPRG
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNDALIDRFCDHLWLEDGLAELTLAAYRRDLRSFAGWLDKTRARSLDAVAPGDVEAYLGW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RFAHHVGPRSAARYTSALKRFYRYLLRENLIAADPTLNLDRPKLPRALPASLSETDVERL
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LERADSDTPQGLRDRAMLETLYATGLRVSELVGLKLNALNLDDGVLRVTGKGNKDRLVPL
HHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCCC
GEEAVRRLRHYLAEARSQLLRRQVSDAVFVTPRGAAMTRQAFWYLIKRRAAAAGVTRQLS
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PHTLRHAFATHLLNHGADLRVVQMLLGHSDISTTQIYTHVARERMKRLHAAHHPRG
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]