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The map label for this gene is yheS [H]

Identifier: 74318369

GI number: 74318369

Start: 2424910

End: 2426862

Strand: Reverse

Name: yheS [H]

Synonym: Tbd_2351

Alternate gene names: 74318369

Gene position: 2426862-2424910 (Counterclockwise)

Preceding gene: 74318371

Following gene: 74318368

Centisome position: 83.4

GC content: 67.38

Gene sequence:

>1953_bases
ATGATCCTCCTGAAGAATCTGAGCCTGCGGCGCGGCGCGAAAGTGCTGCTCGACGACGCCTCGGTCGCGATCAATCCCGG
CGAGAAAGTCGGACTCGTCGGCCGCAACGGCGCCGGAAAATCGAGCCTGTTCGCGCTCCTGAACGGCTCGCTGCATGAAG
ATAAGGGCGACTTCTCGGTCCCGTCGCAATGGCGGCTCGCGCAGGTCGCGCAGGACATGCCCGAGACCGATGCGCCGGCG
ACCGACTTCGTTATCGCCGGCGACACGCGGCTCGTCGCCGCCCAGGCCGAAGTGGAAGCGGCCGAAGCGAGCGACGACGG
CGAACGCATGGCGCACGCCTACATGGCGCTGCACGACGCGGGCGCCCACGACGCCGAATCGCGGGCGCAGGCCTTGATTC
TCGGCCTCGGGTTCCAGGTTCGCGAGCTGAGCCAACCGGTCAACAGCTTCTCCGGCGGATGGCGCATGCGTCTGCAGCTC
GCGCGTGCGCTGATGTGCCCGTCCGATCTGCTGCTGCTCGACGAACCGACCAACCACCTCGACCTCGATGCCCTGGTGTG
GCTCGAGGCCTGGCTGAAGAAATACGCCGGCACGCTGCTGGTGATCAGCCACGACCGCGATTTCCTCGACGCCGTCACCG
ACGTCACGCTCCACATCGAGAACGGCCGGCTGACCCGCTACGGCGGCAACTACAGCACCTTCGAGGACATGCGCGTCGAG
CAGATGGCCTTGCAGCAGGCAGCCTACGCCCGTCAGCAGGAAAAGATCGCCCATCTCAAGAAGTTCATTGATCGCTTCAA
GGCCAAGGCGAGCAAGGCCAAGCAGGCGCAAAGCCGGGTCAAGGCGCTCGACCGCATGGAGCGCCTCGCGCCGCTCCTCG
CCGACGCCGAGTTCTCGTTCGAATTCCAGGAACCCGAGAGCCTGCCGAACCCGATGCTCACGATCGACGACGCGAGCTTC
GGCTACCCCCCGCCCGACGGGGCGCCGGCCGGCACGCCGCCGACCGTGATCGTCCAGCACGTCAGCAGGTCGGTATTCGC
CGGCCAGCGCATCGGCATCCTCGGTGCCAACGGCCAGGGCAAGTCGACGCTCGTGAAGACGATCGCGCGCACGCTGCCCG
TCGTCGCCGGCAGCGTGATTGAAGGCAAGGGCCTCAACATCGGCTATTTCGCGCAGCAGGAGCTCGACGTGCTGCGTCCG
GCCGACACGCCGCTCGAGCACATGATCCGGCTCGCGCGCGACGTCATCGCCAACGGCGGCGCCGGCCGCTTCAGCAGCCG
CGAACAGGACCTGCGCAATTTCCTCGGCACCTTCAATTTCAGCGGCGACATGGTCAAGCAGGCGGTCGGCAGCATGAGCG
GCGGCGAGAAGGCGCGCCTCGTGCTGTGCATGATCGTGTGGCAGCGGCCGAATCTGCTGCTGCTCGACGAGCCGACCAAC
CACCTCGACCTCGCGACGCGCGAGGCGCTCGCGATGGCCTTGAACGAGTTCGAGGGGACGCTGATGCTGGTCAGTCACGA
CCGCGCCCTGCTGCGTTCGGTGTGCGACGAGTTCTGGCTTGTCACGCGCGGCGGCGTCGTGCCCTTCGACGGCGATCTCG
ACGACTACCAGCGCTACCTGCTCGACGAGGCGAAACGCCTGCGCGAAAGCCTGAAGGCGGCGGACAAGGCGGTGGAAACG
CCCGCGCCGAAGGCGCCGCTGGCGCCCGCGAAGCGTGCGCCCTCGGGCAAGCTCAAGCCGCTCAAGCAGTCGCTCGAGAA
GAGCGAGCAACGCCTCGCGGCGTTGCAGGCCGAAAAGGCCACGCTCGAGGCGCGTCTCGACGGCGCCGTCGCGCGCGACG
AAATCGCCGCGGCTGGCACCCGGCTTCAACAGCTCGCCGACGAACTCGAGCGCGAAGAAGAAAGGTGGCTGCAGATATCG
GGAGAGATCGAGACGCACGAGGCGAGCGCCTGA

Upstream 100 bases:

>100_bases
TTCAACAGCTCACGGCCAGGCGCCTGCCGGGCACCCGTGCACGACACGGTAGAATTCGGCTTTTCCTTGGGGCGACGGGC
TGCGGCGCGTCGCATCGTGC

Downstream 100 bases:

>100_bases
GCCGCCGCGGTCGCTTGGATTCCGCGCGCCGCCCGCCTATGCTGCACAGGCCAAAGGCGCAGCGAATTGCCGAGGGATTT
CAATGCCGACATCCGAGCAG

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MILLKNLSLRRGAKVLLDDASVAINPGEKVGLVGRNGAGKSSLFALLNGSLHEDKGDFSVPSQWRLAQVAQDMPETDAPA
TDFVIAGDTRLVAAQAEVEAAEASDDGERMAHAYMALHDAGAHDAESRAQALILGLGFQVRELSQPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLKKYAGTLLVISHDRDFLDAVTDVTLHIENGRLTRYGGNYSTFEDMRVE
QMALQQAAYARQQEKIAHLKKFIDRFKAKASKAKQAQSRVKALDRMERLAPLLADAEFSFEFQEPESLPNPMLTIDDASF
GYPPPDGAPAGTPPTVIVQHVSRSVFAGQRIGILGANGQGKSTLVKTIARTLPVVAGSVIEGKGLNIGYFAQQELDVLRP
ADTPLEHMIRLARDVIANGGAGRFSSREQDLRNFLGTFNFSGDMVKQAVGSMSGGEKARLVLCMIVWQRPNLLLLDEPTN
HLDLATREALAMALNEFEGTLMLVSHDRALLRSVCDEFWLVTRGGVVPFDGDLDDYQRYLLDEAKRLRESLKAADKAVET
PAPKAPLAPAKRAPSGKLKPLKQSLEKSEQRLAALQAEKATLEARLDGAVARDEIAAAGTRLQQLADELEREEERWLQIS
GEIETHEASA

Sequences:

>Translated_650_residues
MILLKNLSLRRGAKVLLDDASVAINPGEKVGLVGRNGAGKSSLFALLNGSLHEDKGDFSVPSQWRLAQVAQDMPETDAPA
TDFVIAGDTRLVAAQAEVEAAEASDDGERMAHAYMALHDAGAHDAESRAQALILGLGFQVRELSQPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLKKYAGTLLVISHDRDFLDAVTDVTLHIENGRLTRYGGNYSTFEDMRVE
QMALQQAAYARQQEKIAHLKKFIDRFKAKASKAKQAQSRVKALDRMERLAPLLADAEFSFEFQEPESLPNPMLTIDDASF
GYPPPDGAPAGTPPTVIVQHVSRSVFAGQRIGILGANGQGKSTLVKTIARTLPVVAGSVIEGKGLNIGYFAQQELDVLRP
ADTPLEHMIRLARDVIANGGAGRFSSREQDLRNFLGTFNFSGDMVKQAVGSMSGGEKARLVLCMIVWQRPNLLLLDEPTN
HLDLATREALAMALNEFEGTLMLVSHDRALLRSVCDEFWLVTRGGVVPFDGDLDDYQRYLLDEAKRLRESLKAADKAVET
PAPKAPLAPAKRAPSGKLKPLKQSLEKSEQRLAALQAEKATLEARLDGAVARDEIAAAGTRLQQLADELEREEERWLQIS
GEIETHEASA
>Mature_650_residues
MILLKNLSLRRGAKVLLDDASVAINPGEKVGLVGRNGAGKSSLFALLNGSLHEDKGDFSVPSQWRLAQVAQDMPETDAPA
TDFVIAGDTRLVAAQAEVEAAEASDDGERMAHAYMALHDAGAHDAESRAQALILGLGFQVRELSQPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLKKYAGTLLVISHDRDFLDAVTDVTLHIENGRLTRYGGNYSTFEDMRVE
QMALQQAAYARQQEKIAHLKKFIDRFKAKASKAKQAQSRVKALDRMERLAPLLADAEFSFEFQEPESLPNPMLTIDDASF
GYPPPDGAPAGTPPTVIVQHVSRSVFAGQRIGILGANGQGKSTLVKTIARTLPVVAGSVIEGKGLNIGYFAQQELDVLRP
ADTPLEHMIRLARDVIANGGAGRFSSREQDLRNFLGTFNFSGDMVKQAVGSMSGGEKARLVLCMIVWQRPNLLLLDEPTN
HLDLATREALAMALNEFEGTLMLVSHDRALLRSVCDEFWLVTRGGVVPFDGDLDDYQRYLLDEAKRLRESLKAADKAVET
PAPKAPLAPAKRAPSGKLKPLKQSLEKSEQRLAALQAEKATLEARLDGAVARDEIAAAGTRLQQLADELEREEERWLQIS
GEIETHEASA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=556, Percent_Identity=36.8705035971223, Blast_Score=350, Evalue=2e-96,
Organism=Homo sapiens, GI27881506, Length=543, Percent_Identity=34.4383057090239, Blast_Score=317, Evalue=2e-86,
Organism=Homo sapiens, GI10947137, Length=543, Percent_Identity=34.4383057090239, Blast_Score=317, Evalue=3e-86,
Organism=Homo sapiens, GI10947135, Length=557, Percent_Identity=33.9317773788151, Blast_Score=262, Evalue=8e-70,
Organism=Homo sapiens, GI69354671, Length=557, Percent_Identity=33.9317773788151, Blast_Score=262, Evalue=1e-69,
Organism=Homo sapiens, GI255708477, Length=314, Percent_Identity=22.9299363057325, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789751, Length=649, Percent_Identity=46.6872110939908, Blast_Score=573, Evalue=1e-164,
Organism=Escherichia coli, GI1787041, Length=546, Percent_Identity=32.6007326007326, Blast_Score=292, Evalue=6e-80,
Organism=Escherichia coli, GI1787182, Length=529, Percent_Identity=31.1909262759924, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI2367384, Length=539, Percent_Identity=30.2411873840445, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1788506, Length=256, Percent_Identity=27.34375, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786345, Length=210, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790190, Length=226, Percent_Identity=25.2212389380531, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI145693107, Length=581, Percent_Identity=21.1703958691911, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=28.2722513089005, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787029, Length=231, Percent_Identity=24.6753246753247, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081709, Length=234, Percent_Identity=24.7863247863248, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786398, Length=215, Percent_Identity=26.5116279069767, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=549, Percent_Identity=35.8834244080146, Blast_Score=333, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17559834, Length=570, Percent_Identity=33.1578947368421, Blast_Score=304, Evalue=8e-83,
Organism=Caenorhabditis elegans, GI17555318, Length=562, Percent_Identity=32.9181494661922, Blast_Score=291, Evalue=7e-79,
Organism=Saccharomyces cerevisiae, GI6321121, Length=556, Percent_Identity=33.6330935251799, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6320874, Length=545, Percent_Identity=33.9449541284404, Blast_Score=310, Evalue=6e-85,
Organism=Saccharomyces cerevisiae, GI6325030, Length=402, Percent_Identity=29.8507462686567, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324314, Length=396, Percent_Identity=27.2727272727273, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6323278, Length=396, Percent_Identity=26.7676767676768, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24666836, Length=551, Percent_Identity=38.8384754990926, Blast_Score=384, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24642252, Length=546, Percent_Identity=34.981684981685, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI18859989, Length=546, Percent_Identity=34.981684981685, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI24641342, Length=558, Percent_Identity=31.3620071684588, Blast_Score=279, Evalue=4e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71104; Mature: 71104

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLKNLSLRRGAKVLLDDASVAINPGEKVGLVGRNGAGKSSLFALLNGSLHEDKGDFSV
CEEEECCCCCCCCEEEEECCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCC
PSQWRLAQVAQDMPETDAPATDFVIAGDTRLVAAQAEVEAAEASDDGERMAHAYMALHDA
CCHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHCC
GAHDAESRAQALILGLGFQVRELSQPVNSFSGGWRMRLQLARALMCPSDLLLLDEPTNHL
CCCCHHHHHHEEHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
DLDALVWLEAWLKKYAGTLLVISHDRDFLDAVTDVTLHIENGRLTRYGGNYSTFEDMRVE
CHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCEEEEEECCEEEEECCCCCCHHHHHHH
QMALQQAAYARQQEKIAHLKKFIDRFKAKASKAKQAQSRVKALDRMERLAPLLADAEFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
EFQEPESLPNPMLTIDDASFGYPPPDGAPAGTPPTVIVQHVSRSVFAGQRIGILGANGQG
EECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCC
KSTLVKTIARTLPVVAGSVIEGKGLNIGYFAQQELDVLRPADTPLEHMIRLARDVIANGG
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
AGRFSSREQDLRNFLGTFNFSGDMVKQAVGSMSGGEKARLVLCMIVWQRPNLLLLDEPTN
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHEEEEEEEECCCCEEEEECCCC
HLDLATREALAMALNEFEGTLMLVSHDRALLRSVCDEFWLVTRGGVVPFDGDLDDYQRYL
CHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEHHCCCCCCCCCCHHHHHHHH
LDEAKRLRESLKAADKAVETPAPKAPLAPAKRAPSGKLKPLKQSLEKSEQRLAALQAEKA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TLEARLDGAVARDEIAAAGTRLQQLADELEREEERWLQISGEIETHEASA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC
>Mature Secondary Structure
MILLKNLSLRRGAKVLLDDASVAINPGEKVGLVGRNGAGKSSLFALLNGSLHEDKGDFSV
CEEEECCCCCCCCEEEEECCCEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCC
PSQWRLAQVAQDMPETDAPATDFVIAGDTRLVAAQAEVEAAEASDDGERMAHAYMALHDA
CCHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHCC
GAHDAESRAQALILGLGFQVRELSQPVNSFSGGWRMRLQLARALMCPSDLLLLDEPTNHL
CCCCHHHHHHEEHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
DLDALVWLEAWLKKYAGTLLVISHDRDFLDAVTDVTLHIENGRLTRYGGNYSTFEDMRVE
CHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHCCEEEEEECCEEEEECCCCCCHHHHHHH
QMALQQAAYARQQEKIAHLKKFIDRFKAKASKAKQAQSRVKALDRMERLAPLLADAEFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
EFQEPESLPNPMLTIDDASFGYPPPDGAPAGTPPTVIVQHVSRSVFAGQRIGILGANGQG
EECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCC
KSTLVKTIARTLPVVAGSVIEGKGLNIGYFAQQELDVLRPADTPLEHMIRLARDVIANGG
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
AGRFSSREQDLRNFLGTFNFSGDMVKQAVGSMSGGEKARLVLCMIVWQRPNLLLLDEPTN
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHEEEEEEEECCCCEEEEECCCC
HLDLATREALAMALNEFEGTLMLVSHDRALLRSVCDEFWLVTRGGVVPFDGDLDDYQRYL
CHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEHHCCCCCCCCCCHHHHHHHH
LDEAKRLRESLKAADKAVETPAPKAPLAPAKRAPSGKLKPLKQSLEKSEQRLAALQAEKA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TLEARLDGAVARDEIAAAGTRLQQLADELEREEERWLQISGEIETHEASA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]