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The map label for this gene is ubiH [H]

Identifier: 74318351

GI number: 74318351

Start: 2406620

End: 2407756

Strand: Reverse

Name: ubiH [H]

Synonym: Tbd_2333

Alternate gene names: 74318351

Gene position: 2407756-2406620 (Counterclockwise)

Preceding gene: 74318352

Following gene: 74318350

Centisome position: 82.75

GC content: 73.0

Gene sequence:

>1137_bases
GTGAACGAGGTCATCGTCGTCGGCGCCGGACCCGTGGGAGCCGTCAGTGCGCTGGCCTTGCAACAGCACGGCGTCGCCGC
GCGCGTGCTCGAAGCGCGCGCCGAGGACGCCCGCGCCGATACGCGGACCCTGGCGCTCGCGCACGGCGCGCGTCTGATTC
TCGAGCGGCTCGGGGTCTGGGCCCGCGTGCAGGACGTCACGCCGATCACGCGCATCCACATCTCGCAGCGCGGCGCGCTC
GGCGTGACCCGGCTCTCCGCCGAGGCGCTCGGCGTCCCGGCCCTCGGTTACGTACTGTCCTACGCGCACCTGACCGAGGT
GCTGAAGCAGGCGCTGGCTGAAGCGCCCATCGCCGTCGAGTACGGCGTGCCGGTCGAGCGCATCGAACCGGGCATCGAGG
CAGCCTGCGTACAGGCGGCGGACGGTCGCACCTGGTCGGCCCCACTCGTCGCGGTCGCCGACGGCGGACGGGGCACGCAG
ACGCCCGCGCCGCGCTTCGCGCACGATTACGCGCAGACGGCCGTGGTGTGCGAAGTGCGGACCGAGCTCGCGCACGGCGG
GCAGGCCTTCGAGCGCTTCACGCCGGAAGGCCCGGCGGCCTTGCTACCCAAGCGCGACGGCTACGCGCTGGTGTGGACCG
CCGCGAGCGCCGAGGCCATGCGTATCGCCGCATTGTCCGACGCGGAATTTCTTGCCGCGCTCCAGCGCCATTTCGGCGGG
CGCCAGGGCTTGTTCCTCGCCGCGACGCCGCGCAAGACCTTTCCGCTGCATTGTGTCTACGCCGGGCGCGAAGTCGGCGC
GCGCGTCGTGCGCATCGGCAACGCGGCCCAGACGCTGCATCCGGTCGCAGGCCAGGGTTTCAACATCGGCCTGCGCGACG
CCTGGGAGCTCGCGCGCCTCTGTGCCGACACCCCGGCGACCGCCCTCGGCGGCGAGGCGATGCTGCACGCCTACGCGCGC
GGCCGCCGCTTCGACGTCGTCGCCGGACTCGGCTTCACCGACTTCCTGGTGCGCATGTTTTCGAACGACGTCGCGGTGCT
GCGTCACGCCCGCGGGCTCGGCTTGCTGGCGCTCGAGGCGCTGCCGCCGCTGAAGGCCTTCGTCGCGCGGCGCATGATGT
TCGGGGCGCGCGGGTGA

Upstream 100 bases:

>100_bases
GCATTCGCATCGAGGACGACGTCGCCGTGACCGAATCCGCGTGCGAGGTGCTGACCCATGCACCGAAGACCGTCGCCGAG
ATCGAGGCGTGGATGCGTCC

Downstream 100 bases:

>100_bases
GCCGCGCCCGCCATCAGGTAGTGGTCGTCGGCGCTGGCCTCGTCGGCGCCGCAACGGCACTCGCGCTCGCGCGACAAGGC
CTGCGCGTGGCCTTGATCGA

Product: 2-octaprenyl-6-methoxyphenol hydroxylase / 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNEVIVVGAGPVGAVSALALQQHGVAARVLEARAEDARADTRTLALAHGARLILERLGVWARVQDVTPITRIHISQRGAL
GVTRLSAEALGVPALGYVLSYAHLTEVLKQALAEAPIAVEYGVPVERIEPGIEAACVQAADGRTWSAPLVAVADGGRGTQ
TPAPRFAHDYAQTAVVCEVRTELAHGGQAFERFTPEGPAALLPKRDGYALVWTAASAEAMRIAALSDAEFLAALQRHFGG
RQGLFLAATPRKTFPLHCVYAGREVGARVVRIGNAAQTLHPVAGQGFNIGLRDAWELARLCADTPATALGGEAMLHAYAR
GRRFDVVAGLGFTDFLVRMFSNDVAVLRHARGLGLLALEALPPLKAFVARRMMFGARG

Sequences:

>Translated_378_residues
MNEVIVVGAGPVGAVSALALQQHGVAARVLEARAEDARADTRTLALAHGARLILERLGVWARVQDVTPITRIHISQRGAL
GVTRLSAEALGVPALGYVLSYAHLTEVLKQALAEAPIAVEYGVPVERIEPGIEAACVQAADGRTWSAPLVAVADGGRGTQ
TPAPRFAHDYAQTAVVCEVRTELAHGGQAFERFTPEGPAALLPKRDGYALVWTAASAEAMRIAALSDAEFLAALQRHFGG
RQGLFLAATPRKTFPLHCVYAGREVGARVVRIGNAAQTLHPVAGQGFNIGLRDAWELARLCADTPATALGGEAMLHAYAR
GRRFDVVAGLGFTDFLVRMFSNDVAVLRHARGLGLLALEALPPLKAFVARRMMFGARG
>Mature_378_residues
MNEVIVVGAGPVGAVSALALQQHGVAARVLEARAEDARADTRTLALAHGARLILERLGVWARVQDVTPITRIHISQRGAL
GVTRLSAEALGVPALGYVLSYAHLTEVLKQALAEAPIAVEYGVPVERIEPGIEAACVQAADGRTWSAPLVAVADGGRGTQ
TPAPRFAHDYAQTAVVCEVRTELAHGGQAFERFTPEGPAALLPKRDGYALVWTAASAEAMRIAALSDAEFLAALQRHFGG
RQGLFLAATPRKTFPLHCVYAGREVGARVVRIGNAAQTLHPVAGQGFNIGLRDAWELARLCADTPATALGGEAMLHAYAR
GRRFDVVAGLGFTDFLVRMFSNDVAVLRHARGLGLLALEALPPLKAFVARRMMFGARG

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Escherichia coli, GI1789274, Length=390, Percent_Identity=36.9230769230769, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1786883, Length=374, Percent_Identity=32.0855614973262, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789273, Length=392, Percent_Identity=29.3367346938776, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 40031; Mature: 40031

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVIVVGAGPVGAVSALALQQHGVAARVLEARAEDARADTRTLALAHGARLILERLGVW
CCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
ARVQDVTPITRIHISQRGALGVTRLSAEALGVPALGYVLSYAHLTEVLKQALAEAPIAVE
EEECCCCCEEEEEECCCCCCEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
YGVPVERIEPGIEAACVQAADGRTWSAPLVAVADGGRGTQTPAPRFAHDYAQTAVVCEVR
CCCCHHHHCCCHHHHHEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
TELAHGGQAFERFTPEGPAALLPKRDGYALVWTAASAEAMRIAALSDAEFLAALQRHFGG
HHHHCCCHHHHHCCCCCCCEECCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHCCC
RQGLFLAATPRKTFPLHCVYAGREVGARVVRIGNAAQTLHPVAGQGFNIGLRDAWELARL
CCCEEEEECCCCCCCEEEEECCHHHCCEEEEECCHHHHHCCCCCCCCCCCHHHHHHHHHH
CADTPATALGGEAMLHAYARGRRFDVVAGLGFTDFLVRMFSNDVAVLRHARGLGLLALEA
HCCCCCHHCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHCCCCEEEEHH
LPPLKAFVARRMMFGARG
CCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNEVIVVGAGPVGAVSALALQQHGVAARVLEARAEDARADTRTLALAHGARLILERLGVW
CCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
ARVQDVTPITRIHISQRGALGVTRLSAEALGVPALGYVLSYAHLTEVLKQALAEAPIAVE
EEECCCCCEEEEEECCCCCCEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
YGVPVERIEPGIEAACVQAADGRTWSAPLVAVADGGRGTQTPAPRFAHDYAQTAVVCEVR
CCCCHHHHCCCHHHHHEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
TELAHGGQAFERFTPEGPAALLPKRDGYALVWTAASAEAMRIAALSDAEFLAALQRHFGG
HHHHCCCHHHHHCCCCCCCEECCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHCCC
RQGLFLAATPRKTFPLHCVYAGREVGARVVRIGNAAQTLHPVAGQGFNIGLRDAWELARL
CCCEEEEECCCCCCCEEEEECCHHHCCEEEEECCHHHHHCCCCCCCCCCCHHHHHHHHHH
CADTPATALGGEAMLHAYARGRRFDVVAGLGFTDFLVRMFSNDVAVLRHARGLGLLALEA
HCCCCCHHCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHCCCCEEEEHH
LPPLKAFVARRMMFGARG
CCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]