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The map label for this gene is mogA [H]

Identifier: 74318161

GI number: 74318161

Start: 2228852

End: 2229406

Strand: Direct

Name: mogA [H]

Synonym: Tbd_2143

Alternate gene names: 74318161

Gene position: 2228852-2229406 (Clockwise)

Preceding gene: 74318158

Following gene: 74318162

Centisome position: 76.6

GC content: 67.93

Gene sequence:

>555_bases
ATGAACCACGATTCCGTCCGTGTCGGTCTGGTCTCGATCAGCGACCGCGCCAGCAGCGGCATTTACGAAGACCAGGGGCT
GCCCGCGTTGCAGACCTGGCTGGGCGAGGTGCTCGCCAATCCCGTCGAATTCGTCACGCGCCTGATCCCCGACGAGCAGG
AGCGCATCGAGGCCGTGCTGATCGAACTCGCCGACGGCGAACGCTGTTCGCTGATTCTGACCACCGGCGGCACCGGCCCG
GCGCCGCGCGACGTGACGCCCGAAGCGACGCTGGCCGTCGCGCACAAGGTATTGCCCGGTTTCGGCGAAGCCATGCGCGC
GGTGTCGCTCAAATACGTGCCGACCGCGATCCTCTCGCGCCAGGTCGGCGTCACGCGTGGCGCGAGCCTGATCCTCAATC
TGCCGGGGCAGCCCAAGGCGATCAAGGAAACGCTCGACGGCGTCTTCGCCGCAGTCCCCTATTGCGTCGACCTCATAGGC
GGCCCCTATCTCGAAGCTCGGCCCGGCACGGTCGCGGTGTTCCGCCCGAAGTCGGCGCTGCGGCCGCCAGCATGA

Upstream 100 bases:

>100_bases
CATCAGAAGAATTCTCGTCAGCCTCATTTTTGACTCCCGCGGCAGTGTCGCCCCCATTCTGCTAGATTGAAGCCCTCCCG
CAACCCTCCTTTTTGACCAT

Downstream 100 bases:

>100_bases
GCACGGTTATTGCGGCGGCCGCGGGCGCGTTGCGCGATCTGTTCAGCCTGCGTGTGCTCTGGATCATCGTCTGGCCGATC
CTGGTCGCGACCCTGCTATG

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNHDSVRVGLVSISDRASSGIYEDQGLPALQTWLGEVLANPVEFVTRLIPDEQERIEAVLIELADGERCSLILTTGGTGP
APRDVTPEATLAVAHKVLPGFGEAMRAVSLKYVPTAILSRQVGVTRGASLILNLPGQPKAIKETLDGVFAAVPYCVDLIG
GPYLEARPGTVAVFRPKSALRPPA

Sequences:

>Translated_184_residues
MNHDSVRVGLVSISDRASSGIYEDQGLPALQTWLGEVLANPVEFVTRLIPDEQERIEAVLIELADGERCSLILTTGGTGP
APRDVTPEATLAVAHKVLPGFGEAMRAVSLKYVPTAILSRQVGVTRGASLILNLPGQPKAIKETLDGVFAAVPYCVDLIG
GPYLEARPGTVAVFRPKSALRPPA
>Mature_184_residues
MNHDSVRVGLVSISDRASSGIYEDQGLPALQTWLGEVLANPVEFVTRLIPDEQERIEAVLIELADGERCSLILTTGGTGP
APRDVTPEATLAVAHKVLPGFGEAMRAVSLKYVPTAILSRQVGVTRGASLILNLPGQPKAIKETLDGVFAAVPYCVDLIG
GPYLEARPGTVAVFRPKSALRPPA

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=161, Percent_Identity=40.3726708074534, Blast_Score=111, Evalue=4e-25,
Organism=Homo sapiens, GI66932975, Length=161, Percent_Identity=40.3726708074534, Blast_Score=111, Evalue=4e-25,
Organism=Escherichia coli, GI1786190, Length=190, Percent_Identity=63.1578947368421, Blast_Score=241, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17564954, Length=157, Percent_Identity=37.5796178343949, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17136978, Length=157, Percent_Identity=40.1273885350318, Blast_Score=106, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24638841, Length=157, Percent_Identity=40.1273885350318, Blast_Score=106, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19477; Mature: 19477

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHDSVRVGLVSISDRASSGIYEDQGLPALQTWLGEVLANPVEFVTRLIPDEQERIEAVL
CCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHH
IELADGERCSLILTTGGTGPAPRDVTPEATLAVAHKVLPGFGEAMRAVSLKYVPTAILSR
HCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QVGVTRGASLILNLPGQPKAIKETLDGVFAAVPYCVDLIGGPYLEARPGTVAVFRPKSAL
HCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECCHHCC
RPPA
CCCC
>Mature Secondary Structure
MNHDSVRVGLVSISDRASSGIYEDQGLPALQTWLGEVLANPVEFVTRLIPDEQERIEAVL
CCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHH
IELADGERCSLILTTGGTGPAPRDVTPEATLAVAHKVLPGFGEAMRAVSLKYVPTAILSR
HCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QVGVTRGASLILNLPGQPKAIKETLDGVFAAVPYCVDLIGGPYLEARPGTVAVFRPKSAL
HCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECCHHCC
RPPA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]