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The map label for this gene is corA [H]

Identifier: 74318158

GI number: 74318158

Start: 2226087

End: 2227058

Strand: Direct

Name: corA [H]

Synonym: Tbd_2140

Alternate gene names: 74318158

Gene position: 2226087-2227058 (Clockwise)

Preceding gene: 74318157

Following gene: 74318161

Centisome position: 76.5

GC content: 64.81

Gene sequence:

>972_bases
GTGAGGAGTGCCATCATCGACTGCCTGCTCTTCCACGACGGCAAGGTGCAATCGATCGCGTTCGAGGACATCAGCGACCA
CGTCGGCGATCCCGAGCGTTTTCTCTGGGTCGAGCTCAAATCTCCCGACGTGCATACGGTGGCCAAGCTCGGCGACGAGT
TCGGCCTGCACGAACTCGCGCTCGAGGATGCGATCTCGACGCACCAGCGGCCCAAGCTCGAGGAATACGGCGAACACCTG
TTCATCGCCGTGCGCACGGTCCAGCTCTGGCAGACGCGGATCGAGATCGGCGAAACCCACGTCTTCGCCGGCGCCAATTT
CGTCATCGCGATCCGCCACGGCGCCGGCAGCAACTACACCCGCGTCGCCGAACGACTGCGTGCGCCGAAGAACGGCATCC
GTCCCGGCGCGCCCTACGCGCTATATCTCGTGCTCGACCTCATCGTCGATCAATTGAAACCGGTCATGGACGGGCTGCAC
GAGCGTTTCCAGTCGGTCGAGAGCGTCCTCGTCGGCGGCGAACTGCGCCGCGGCAATCTCGAGCACCTCTATGCGCTGAA
GCGCGACCTGACGCAACTGCGCGACGCGGTCGACCCGGTGCAGGACATCACGCAGGACCTCATCCGCCTGCATCCCGAAT
TCGTCGTGCGCGAACTCAAGGCCTATTACCGCGACGTGCATGACCACGCGGCACGCATCTCCGCGGCGATCGGCCACTTG
CGCAATTCGGCCTCGGACGCGATGCAGTTCCACCTCGCGTCGCTCTCGCTGCAGCAGAACGAGTCAGTGCAGAAGCTCGC
GGGCTGGGGCGCGTTGCTCGCCCTGCCGACGGTGATCTTCAGTCTCTACGGCATGAATTTCCGCCACATGCCCGAACTCG
AATGGCCCTGGGCCTACCCGGCCCTGCTCCTCGGCACGGGGGCTGCGGCAGTCGTGCTGTATCGGCGGCTCAAGCGCCGC
GGCTGGATATAG

Upstream 100 bases:

>100_bases
GCTCTACACCGATCTGCGCCGCGGCGTTTCAGCCGCCTGACACGGCGCGGCGCCACGGGCGCGCGATACGGCGTCTAGAA
TTCAGGCTCATCATCCTTAG

Downstream 100 bases:

>100_bases
GATCGGCGCCGACGCCGGATCTACCGTCCAACGGCGCGGCTCGACTCAAGATGGCGTGGCGTCCCCCTGGCATAGCGGAT
ACGTGCACCCTTGGCCTCGT

Product: magnesium/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MRSAIIDCLLFHDGKVQSIAFEDISDHVGDPERFLWVELKSPDVHTVAKLGDEFGLHELALEDAISTHQRPKLEEYGEHL
FIAVRTVQLWQTRIEIGETHVFAGANFVIAIRHGAGSNYTRVAERLRAPKNGIRPGAPYALYLVLDLIVDQLKPVMDGLH
ERFQSVESVLVGGELRRGNLEHLYALKRDLTQLRDAVDPVQDITQDLIRLHPEFVVRELKAYYRDVHDHAARISAAIGHL
RNSASDAMQFHLASLSLQQNESVQKLAGWGALLALPTVIFSLYGMNFRHMPELEWPWAYPALLLGTGAAAVVLYRRLKRR
GWI

Sequences:

>Translated_323_residues
MRSAIIDCLLFHDGKVQSIAFEDISDHVGDPERFLWVELKSPDVHTVAKLGDEFGLHELALEDAISTHQRPKLEEYGEHL
FIAVRTVQLWQTRIEIGETHVFAGANFVIAIRHGAGSNYTRVAERLRAPKNGIRPGAPYALYLVLDLIVDQLKPVMDGLH
ERFQSVESVLVGGELRRGNLEHLYALKRDLTQLRDAVDPVQDITQDLIRLHPEFVVRELKAYYRDVHDHAARISAAIGHL
RNSASDAMQFHLASLSLQQNESVQKLAGWGALLALPTVIFSLYGMNFRHMPELEWPWAYPALLLGTGAAAVVLYRRLKRR
GWI
>Mature_323_residues
MRSAIIDCLLFHDGKVQSIAFEDISDHVGDPERFLWVELKSPDVHTVAKLGDEFGLHELALEDAISTHQRPKLEEYGEHL
FIAVRTVQLWQTRIEIGETHVFAGANFVIAIRHGAGSNYTRVAERLRAPKNGIRPGAPYALYLVLDLIVDQLKPVMDGLH
ERFQSVESVLVGGELRRGNLEHLYALKRDLTQLRDAVDPVQDITQDLIRLHPEFVVRELKAYYRDVHDHAARISAAIGHL
RNSASDAMQFHLASLSLQQNESVQKLAGWGALLALPTVIFSLYGMNFRHMPELEWPWAYPALLLGTGAAAVVLYRRLKRR
GWI

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36526; Mature: 36526

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAIIDCLLFHDGKVQSIAFEDISDHVGDPERFLWVELKSPDVHTVAKLGDEFGLHELA
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCHHHHH
LEDAISTHQRPKLEEYGEHLFIAVRTVQLWQTRIEIGETHVFAGANFVIAIRHGAGSNYT
HHHHHHHCCCCCHHHHCCEEEHHHHHHHHHHHHHHHCCEEEEECCCEEEEEEECCCCCHH
RVAERLRAPKNGIRPGAPYALYLVLDLIVDQLKPVMDGLHERFQSVESVLVGGELRRGNL
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EHLYALKRDLTQLRDAVDPVQDITQDLIRLHPEFVVRELKAYYRDVHDHAARISAAIGHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNSASDAMQFHLASLSLQQNESVQKLAGWGALLALPTVIFSLYGMNFRHMPELEWPWAYP
HCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
ALLLGTGAAAVVLYRRLKRRGWI
HHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSAIIDCLLFHDGKVQSIAFEDISDHVGDPERFLWVELKSPDVHTVAKLGDEFGLHELA
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCHHHHH
LEDAISTHQRPKLEEYGEHLFIAVRTVQLWQTRIEIGETHVFAGANFVIAIRHGAGSNYT
HHHHHHHCCCCCHHHHCCEEEHHHHHHHHHHHHHHHCCEEEEECCCEEEEEEECCCCCHH
RVAERLRAPKNGIRPGAPYALYLVLDLIVDQLKPVMDGLHERFQSVESVLVGGELRRGNL
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EHLYALKRDLTQLRDAVDPVQDITQDLIRLHPEFVVRELKAYYRDVHDHAARISAAIGHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNSASDAMQFHLASLSLQQNESVQKLAGWGALLALPTVIFSLYGMNFRHMPELEWPWAYP
HCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
ALLLGTGAAAVVLYRRLKRRGWI
HHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]