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The map label for this gene is resA [H]

Identifier: 74318136

GI number: 74318136

Start: 2206467

End: 2206961

Strand: Reverse

Name: resA [H]

Synonym: Tbd_2118

Alternate gene names: 74318136

Gene position: 2206961-2206467 (Counterclockwise)

Preceding gene: 74318139

Following gene: 74318135

Centisome position: 75.85

GC content: 59.19

Gene sequence:

>495_bases
ATGCAGACGTTGCAAAGAACGCGATTTTATCCCATGTGGTTTGGCGCACTGCTGCTCGCACTGGCGGCGAGTGTCGCGCA
GGCGGCGGGTTTCAAGGTGACCGACACCAATGGAAAAACGCACACGCTCGACGGCTACAAGGGAAAGTGGGTGCTGGTGA
ATTACTGGGCGACATGGTGTCCGCCGTGCTTGGAGGAGATCCCCGATCTCATCGCGCTGCACGGCGACAAGAAGAACAAT
CTTGTGGTGATCGGCATCGCGCTTGATTACCGGAATGCCAAGCAGGTCACCGATTTCACCGAGGGTCTCCTCGTCGACTA
TCCGATCGTGCTCGGCAACCACCAGATCGTGAGCCAGATCGGCCCGGTGCGCGGGCTGCCGACGACCTATTTGTTCAACC
CCGAAGGTAAAATGGTCGCGCAGCAGGTCGGTGCCGTCACGCGCGAAGCGGTGGAAAGCTATCTCAAGGGCAAAGGGGCC
CGGCCCGCAAAATAA

Upstream 100 bases:

>100_bases
GCCCGTGCGGTCTGGGCGCCGTACCACGCGTCTCGGGGAACCCGGACTTCGCCGAGCGAGTCCTTCTCGGTGCGGAATTC
ATTCATGATCGGGGGAAGTA

Downstream 100 bases:

>100_bases
TCGGGAGATGTCCATGCGCCAACTGTTTCTTGCTTTCGTCCTGCTACTGGCGGCGCCTGCCTGGGCCGAGACGCGCGATC
CGGCGAGCCATTTCTTCCAG

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MQTLQRTRFYPMWFGALLLALAASVAQAAGFKVTDTNGKTHTLDGYKGKWVLVNYWATWCPPCLEEIPDLIALHGDKKNN
LVVIGIALDYRNAKQVTDFTEGLLVDYPIVLGNHQIVSQIGPVRGLPTTYLFNPEGKMVAQQVGAVTREAVESYLKGKGA
RPAK

Sequences:

>Translated_164_residues
MQTLQRTRFYPMWFGALLLALAASVAQAAGFKVTDTNGKTHTLDGYKGKWVLVNYWATWCPPCLEEIPDLIALHGDKKNN
LVVIGIALDYRNAKQVTDFTEGLLVDYPIVLGNHQIVSQIGPVRGLPTTYLFNPEGKMVAQQVGAVTREAVESYLKGKGA
RPAK
>Mature_164_residues
MQTLQRTRFYPMWFGALLLALAASVAQAAGFKVTDTNGKTHTLDGYKGKWVLVNYWATWCPPCLEEIPDLIALHGDKKNN
LVVIGIALDYRNAKQVTDFTEGLLVDYPIVLGNHQIVSQIGPVRGLPTTYLFNPEGKMVAQQVGAVTREAVESYLKGKGA
RPAK

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 18061; Mature: 18061

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLQRTRFYPMWFGALLLALAASVAQAAGFKVTDTNGKTHTLDGYKGKWVLVNYWATWC
CCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEECCCCCCCEEEEECCHHCC
PPCLEEIPDLIALHGDKKNNLVVIGIALDYRNAKQVTDFTEGLLVDYPIVLGNHQIVSQI
CHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCHHHHHHHCCCEEECCEEECCHHHHHHC
GPVRGLPTTYLFNPEGKMVAQQVGAVTREAVESYLKGKGARPAK
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQTLQRTRFYPMWFGALLLALAASVAQAAGFKVTDTNGKTHTLDGYKGKWVLVNYWATWC
CCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEECCCCCCCEEEEECCHHCC
PPCLEEIPDLIALHGDKKNNLVVIGIALDYRNAKQVTDFTEGLLVDYPIVLGNHQIVSQI
CHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCHHHHHHHCCCEEECCEEECCHHHHHHC
GPVRGLPTTYLFNPEGKMVAQQVGAVTREAVESYLKGKGARPAK
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 12637552 [H]