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The map label for this gene is hypB [H]

Identifier: 74317401

GI number: 74317401

Start: 1461479

End: 1462285

Strand: Direct

Name: hypB [H]

Synonym: Tbd_1383

Alternate gene names: 74317401

Gene position: 1461479-1462285 (Clockwise)

Preceding gene: 74317400

Following gene: 74317402

Centisome position: 50.23

GC content: 66.29

Gene sequence:

>807_bases
ATGTGCGACACCTGCGGCTGCAACCTCACCCCGGGCAACAGGCATCTTGCCTACAAGCCGGTCGCCCGCGGCGCGACCGC
GGTTTCCGTCCTCAAGGGCCTGCTCGCGAAGAACGACGACCAGGCCGGACACAATCGCGCGCACTTCGACCGGCGCGGCA
TCCTCGCGCTCAACCTGATGTCTTCGCCGGGCTCGGGCAAGACAGCGCTGCTCGAAGCGACGCTTACGGCGCTGAAGGGT
GAATTCACCTGCGCGGTGATCGAGGGCGACCTCGAAACCGAGAACGACGCCGAGCGCATCCGTGCCAAAGGGGTGCAGGC
CCACCAGATCGTCACCGGGACGGCCTGCCACCTCGACGCGCATCTCGTGCACGACGCACTGCATGAGATGAAGCTCGACG
GCGTCGACATCCTGTTCATCGAAAACGTGGGCAATCTCGTCTGCCCCGCAAGCTTCGACCTCGGCCAGCATCTCAACGTC
ACGCTGCTCTCGGTCACCGAGGGCGACGACAAACCGGCGAAGTATCCGGTGATGTTCCGTGCGGCCGATGCGCTGCTTTT
GACCAAGACCGATCTGTTGCCGGTGCTCGACGATTTCGACCTTGACCGCGCCGAAGCGCATCTGCGCAATCTCGCGAATC
CGGCGCCGGTGCTACATCTGTCGGCGCGCAAGGATGCCGGAATGGGCCCGTGGCTCGACTGGATCCGCGTGCAGCTGGCG
CAGCAGCTTGCGCGCGTCGCCGCGGGGCAGTCCAGGCGGCCGGCGATCCAGCCCGACGGCGCGCGCTACCACCACACGGA
GGCGTGA

Upstream 100 bases:

>100_bases
CTGGCATACCCGCATCGTCTCCGGAGACGAATTGCTGCTCGAAAGCGTCGAACTCGAAACCGCCGCTTCCCCGTCCCCTG
CATCCTGAGCCCCCCGAAAA

Downstream 100 bases:

>100_bases
TGGACGAAGCACGGATCTGGCTCGAGAAAGTCCACGCGCTCGCGTTCGACCGCAAGGTCAAGATCATGAACGTATGCGGC
GGGCACGAGCGCTCGATCAC

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MCDTCGCNLTPGNRHLAYKPVARGATAVSVLKGLLAKNDDQAGHNRAHFDRRGILALNLMSSPGSGKTALLEATLTALKG
EFTCAVIEGDLETENDAERIRAKGVQAHQIVTGTACHLDAHLVHDALHEMKLDGVDILFIENVGNLVCPASFDLGQHLNV
TLLSVTEGDDKPAKYPVMFRAADALLLTKTDLLPVLDDFDLDRAEAHLRNLANPAPVLHLSARKDAGMGPWLDWIRVQLA
QQLARVAAGQSRRPAIQPDGARYHHTEA

Sequences:

>Translated_268_residues
MCDTCGCNLTPGNRHLAYKPVARGATAVSVLKGLLAKNDDQAGHNRAHFDRRGILALNLMSSPGSGKTALLEATLTALKG
EFTCAVIEGDLETENDAERIRAKGVQAHQIVTGTACHLDAHLVHDALHEMKLDGVDILFIENVGNLVCPASFDLGQHLNV
TLLSVTEGDDKPAKYPVMFRAADALLLTKTDLLPVLDDFDLDRAEAHLRNLANPAPVLHLSARKDAGMGPWLDWIRVQLA
QQLARVAAGQSRRPAIQPDGARYHHTEA
>Mature_268_residues
MCDTCGCNLTPGNRHLAYKPVARGATAVSVLKGLLAKNDDQAGHNRAHFDRRGILALNLMSSPGSGKTALLEATLTALKG
EFTCAVIEGDLETENDAERIRAKGVQAHQIVTGTACHLDAHLVHDALHEMKLDGVDILFIENVGNLVCPASFDLGQHLNV
TLLSVTEGDDKPAKYPVMFRAADALLLTKTDLLPVLDDFDLDRAEAHLRNLANPAPVLHLSARKDAGMGPWLDWIRVQLA
QQLARVAAGQSRRPAIQPDGARYHHTEA

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=205, Percent_Identity=54.6341463414634, Blast_Score=209, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 28946; Mature: 28946

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDTCGCNLTPGNRHLAYKPVARGATAVSVLKGLLAKNDDQAGHNRAHFDRRGILALNLM
CCCCCCCCCCCCCCEEEECCHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEE
SSPGSGKTALLEATLTALKGEFTCAVIEGDLETENDAERIRAKGVQAHQIVTGTACHLDA
CCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCCCEEEEEECCCHHHHH
HLVHDALHEMKLDGVDILFIENVGNLVCPASFDLGQHLNVTLLSVTEGDDKPAKYPVMFR
HHHHHHHHHHCCCCEEEEEEECCCCEECCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEE
AADALLLTKTDLLPVLDDFDLDRAEAHLRNLANPAPVLHLSARKDAGMGPWLDWIRVQLA
ECCEEEEECCCCHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
QQLARVAAGQSRRPAIQPDGARYHHTEA
HHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MCDTCGCNLTPGNRHLAYKPVARGATAVSVLKGLLAKNDDQAGHNRAHFDRRGILALNLM
CCCCCCCCCCCCCCEEEECCHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEE
SSPGSGKTALLEATLTALKGEFTCAVIEGDLETENDAERIRAKGVQAHQIVTGTACHLDA
CCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCCCEEEEEECCCHHHHH
HLVHDALHEMKLDGVDILFIENVGNLVCPASFDLGQHLNVTLLSVTEGDDKPAKYPVMFR
HHHHHHHHHHCCCCEEEEEEECCCCEECCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEE
AADALLLTKTDLLPVLDDFDLDRAEAHLRNLANPAPVLHLSARKDAGMGPWLDWIRVQLA
ECCEEEEECCCCHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
QQLARVAAGQSRRPAIQPDGARYHHTEA
HHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]