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The map label for this gene is hypD [C]

Identifier: 74317402

GI number: 74317402

Start: 1462285

End: 1463382

Strand: Direct

Name: hypD [C]

Synonym: Tbd_1384

Alternate gene names: 74317402

Gene position: 1462285-1463382 (Clockwise)

Preceding gene: 74317401

Following gene: 74317403

Centisome position: 50.25

GC content: 68.76

Gene sequence:

>1098_bases
ATGGACGAAGCACGGATCTGGCTCGAGAAAGTCCACGCGCTCGCGTTCGACCGCAAGGTCAAGATCATGAACGTATGCGG
CGGGCACGAGCGCTCGATCACCCATGCCGGACTGCGCGGCGCGCTGCCGGACTGGCTCGAGCTCGTGCCCGGACCCGGCT
GCCCGGTCTGCGTGTGCCCCGAAGAAGACGTCTACCAGGCGATCCAGCTCGCGCTGCAGGACAGGGTCATTCTCGTCGCC
TACGGCGACATGCTGCGGGTACCGGTCAACGTCAAGAAAGGCGAAATTCGATCACTGGCCGAGGCGCAGGCCGCGGGGGC
GGACGTGCGGCCGATCGCGAGCCCGCTCGACGCCCGCAGGATCGCAGCCGAAAACCCGACGCGGCCCGTGGTGTTCTTCG
CCGCGGGCTTCGAAACGACGACCGCGCCGACCGCCGCCATGCTGGCCGAAGGCGTTCCCGACAATCTGAGCATTCTGCTG
TCCGGGCGCCTGACCTGGCCCGCGGTCGCGATGCTGCTCGACTCGGGCAGCCCCGGCTTCGACGCGCTGATCGCCCCCGG
CCACGTGTCGACCGTGATGGGGCCCGAGGAATGGAACTTCGTCGTCCAACGCCACGAGATCCCCGCCGCGGTCGCCGGGT
TCGGCACGGCCTCGCTGCTCGCCTCCTTCTATTCGGTGCTGCGCCAGCTCGAGAGCGGTGAACGCTTTCTCGACAACTGC
TACCGCGAAGTCGCGCACCCGGACGGGAATCCAACGGCGCGTCGAATGATGGCCCGCGCGTTCGACGTGGTCGACGCGAA
CTGGCGCGGCATCGGCGTGATCGCTCGCTCGGGATACGCACTCAAACCGGGCCTCGCGCAGCACGACGCACGCGTCCTGT
TCGACGACCACACCGATCCGGCGCGCTGGCGCGCCGGCGAAATGCCGCCCGGATGCGACTGCGCGCAAGTCGTTCTCGGC
AAGATCTATCCCAACCAGTGCCGCATCTACGGCAAGGCCTGCACGCCGCGCAAGCCGGTGGGACCGTGCATGGTCTCGGA
CGAAGGCGCCTGCCGCATCTGGTGGGCCGGTGGCGTGCGCGTCGCGGCCGATGCCTGA

Upstream 100 bases:

>100_bases
GCGTGCAGCTGGCGCAGCAGCTTGCGCGCGTCGCCGCGGGGCAGTCCAGGCGGCCGGCGATCCAGCCCGACGGCGCGCGC
TACCACCACACGGAGGCGTG

Downstream 100 bases:

>100_bases
GCGCATCGCGCAATTCATCACGATCGGCGGGCGCGTGCAGGGGGTCGGCTTTCGGCCTTTCGTCTACCGCGCCGCGCGCG
CGCACGCGCTTGCAGGATGG

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MDEARIWLEKVHALAFDRKVKIMNVCGGHERSITHAGLRGALPDWLELVPGPGCPVCVCPEEDVYQAIQLALQDRVILVA
YGDMLRVPVNVKKGEIRSLAEAQAAGADVRPIASPLDARRIAAENPTRPVVFFAAGFETTTAPTAAMLAEGVPDNLSILL
SGRLTWPAVAMLLDSGSPGFDALIAPGHVSTVMGPEEWNFVVQRHEIPAAVAGFGTASLLASFYSVLRQLESGERFLDNC
YREVAHPDGNPTARRMMARAFDVVDANWRGIGVIARSGYALKPGLAQHDARVLFDDHTDPARWRAGEMPPGCDCAQVVLG
KIYPNQCRIYGKACTPRKPVGPCMVSDEGACRIWWAGGVRVAADA

Sequences:

>Translated_365_residues
MDEARIWLEKVHALAFDRKVKIMNVCGGHERSITHAGLRGALPDWLELVPGPGCPVCVCPEEDVYQAIQLALQDRVILVA
YGDMLRVPVNVKKGEIRSLAEAQAAGADVRPIASPLDARRIAAENPTRPVVFFAAGFETTTAPTAAMLAEGVPDNLSILL
SGRLTWPAVAMLLDSGSPGFDALIAPGHVSTVMGPEEWNFVVQRHEIPAAVAGFGTASLLASFYSVLRQLESGERFLDNC
YREVAHPDGNPTARRMMARAFDVVDANWRGIGVIARSGYALKPGLAQHDARVLFDDHTDPARWRAGEMPPGCDCAQVVLG
KIYPNQCRIYGKACTPRKPVGPCMVSDEGACRIWWAGGVRVAADA
>Mature_365_residues
MDEARIWLEKVHALAFDRKVKIMNVCGGHERSITHAGLRGALPDWLELVPGPGCPVCVCPEEDVYQAIQLALQDRVILVA
YGDMLRVPVNVKKGEIRSLAEAQAAGADVRPIASPLDARRIAAENPTRPVVFFAAGFETTTAPTAAMLAEGVPDNLSILL
SGRLTWPAVAMLLDSGSPGFDALIAPGHVSTVMGPEEWNFVVQRHEIPAAVAGFGTASLLASFYSVLRQLESGERFLDNC
YREVAHPDGNPTARRMMARAFDVVDANWRGIGVIARSGYALKPGLAQHDARVLFDDHTDPARWRAGEMPPGCDCAQVVLG
KIYPNQCRIYGKACTPRKPVGPCMVSDEGACRIWWAGGVRVAADA

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=353, Percent_Identity=38.5269121813031, Blast_Score=233, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 39402; Mature: 39402

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEARIWLEKVHALAFDRKVKIMNVCGGHERSITHAGLRGALPDWLELVPGPGCPVCVCP
CCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCCCCHHHHHCCCCCCCEEECC
EEDVYQAIQLALQDRVILVAYGDMLRVPVNVKKGEIRSLAEAQAAGADVRPIASPLDARR
CHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHH
IAAENPTRPVVFFAAGFETTTAPTAAMLAEGVPDNLSILLSGRLTWPAVAMLLDSGSPGF
HHCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCCCC
DALIAPGHVSTVMGPEEWNFVVQRHEIPAAVAGFGTASLLASFYSVLRQLESGERFLDNC
CEEECCCCCEECCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHH
YREVAHPDGNPTARRMMARAFDVVDANWRGIGVIARSGYALKPGLAQHDARVLFDDHTDP
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCEEECCCCCCCCCEEEEECCCCH
ARWRAGEMPPGCDCAQVVLGKIYPNQCRIYGKACTPRKPVGPCMVSDEGACRIWWAGGVR
HHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCCCCEEEEEECCEE
VAADA
EEECC
>Mature Secondary Structure
MDEARIWLEKVHALAFDRKVKIMNVCGGHERSITHAGLRGALPDWLELVPGPGCPVCVCP
CCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCCCCHHHHHCCCCCCCEEECC
EEDVYQAIQLALQDRVILVAYGDMLRVPVNVKKGEIRSLAEAQAAGADVRPIASPLDARR
CHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHH
IAAENPTRPVVFFAAGFETTTAPTAAMLAEGVPDNLSILLSGRLTWPAVAMLLDSGSPGF
HHCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCCCC
DALIAPGHVSTVMGPEEWNFVVQRHEIPAAVAGFGTASLLASFYSVLRQLESGERFLDNC
CEEECCCCCEECCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHH
YREVAHPDGNPTARRMMARAFDVVDANWRGIGVIARSGYALKPGLAQHDARVLFDDHTDP
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCEEECCCCCCCCCEEEEECCCCH
ARWRAGEMPPGCDCAQVVLGKIYPNQCRIYGKACTPRKPVGPCMVSDEGACRIWWAGGVR
HHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCCCCEEEEEECCEE
VAADA
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]