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The map label for this gene is dapD

Identifier: 74317238

GI number: 74317238

Start: 1273921

End: 1274745

Strand: Reverse

Name: dapD

Synonym: Tbd_1220

Alternate gene names: 74317238

Gene position: 1274745-1273921 (Counterclockwise)

Preceding gene: 74317239

Following gene: 74317237

Centisome position: 43.81

GC content: 63.03

Gene sequence:

>825_bases
ATGCAAGAACTCCAGCCCATCATCGAAGAAGCCTTCGAACGCCGCGCCGACATCACGCCGCGCAACGCGACCCCGCAGGT
CAAGGACGCCGTCATGGCCGTCATCGACCTGCTCGACATGGGACAGCTGCGCGTCGCCGAGCGGACGGACGGCCAGAACT
GGACGACGAACCAGTGGGTCAAGAAGGCCGTGCTGCTGTCGTTCCGCCTCGAGGACAACGCCTTCATCAAGGGCGGCTAC
ACCAATTATTACGACAAGGTGCCGTCGAAGTTCGCCGACTTCAACTCGAAGGACTTCCGCGAAGGCGGCTTCCGCGTCGT
GCCGCCTGCGGCCGCGCGCAAGGGCTCCTACATCGGCAAGAACGTCGTGCTGATGCCTTCCTACGTCAACATCGGCGCCT
ACGTCGACGAAGGCACGATGGTCGACACCTGGGCGACGGTTGGTTCCTGCGCGCAGATCGGCAAGAACGTCCACCTCTCG
GGCGGTGTTGGCATCGGCGGCGTGCTCGAGCCGGTGCAGGCCAACCCGACGATCATCGGCGACAACTGCTTCATCGGCGC
GCGTTCCGAAGTCGTCGAGGGCGTGATCGTCGAGGACAACTGCGTGATCTCGATGGGCGTCTACATCGGCCAATCGACCA
AGATCTACGACCGCGAGACCGGCGAAATCCACTACGGCCGCGTGCCGGCCGGCTCGGTCGTCGTCTCCGGCAACCTCCCT
TCCAAGGACGGCAGCTATAGTCTGTATTGTGCGGTGATCGTGAAGAAGGTCGACGCCAAGACGCTGTCCAAGGTCGGCAT
CAACGAACTGCTGCGCGGAATCTGA

Upstream 100 bases:

>100_bases
CGCTCGACGCCTGCGTCGAGGCCGCTGAACGCATCGCGGCCTTCGTCACCGAGGCCGCCTGACTCTTTCTCCAACTTTCT
TGAAACGGACCGCACAGATC

Downstream 100 bases:

>100_bases
GTCTGAATGAACGCGGCGCCTGCCCGGCGTTCGCCCGGGGCATCAGCCGCGACGAAGCTGCACCCCTGATCTTCCTCAAG
GAGCGACCATGAACCGCAAA

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MQELQPIIEEAFERRADITPRNATPQVKDAVMAVIDLLDMGQLRVAERTDGQNWTTNQWVKKAVLLSFRLEDNAFIKGGY
TNYYDKVPSKFADFNSKDFREGGFRVVPPAAARKGSYIGKNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLS
GGVGIGGVLEPVQANPTIIGDNCFIGARSEVVEGVIVEDNCVISMGVYIGQSTKIYDRETGEIHYGRVPAGSVVVSGNLP
SKDGSYSLYCAVIVKKVDAKTLSKVGINELLRGI

Sequences:

>Translated_274_residues
MQELQPIIEEAFERRADITPRNATPQVKDAVMAVIDLLDMGQLRVAERTDGQNWTTNQWVKKAVLLSFRLEDNAFIKGGY
TNYYDKVPSKFADFNSKDFREGGFRVVPPAAARKGSYIGKNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLS
GGVGIGGVLEPVQANPTIIGDNCFIGARSEVVEGVIVEDNCVISMGVYIGQSTKIYDRETGEIHYGRVPAGSVVVSGNLP
SKDGSYSLYCAVIVKKVDAKTLSKVGINELLRGI
>Mature_274_residues
MQELQPIIEEAFERRADITPRNATPQVKDAVMAVIDLLDMGQLRVAERTDGQNWTTNQWVKKAVLLSFRLEDNAFIKGGY
TNYYDKVPSKFADFNSKDFREGGFRVVPPAAARKGSYIGKNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLS
GGVGIGGVLEPVQANPTIIGDNCFIGARSEVVEGVIVEDNCVISMGVYIGQSTKIYDRETGEIHYGRVPAGSVVVSGNLP
SKDGSYSLYCAVIVKKVDAKTLSKVGINELLRGI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=274, Percent_Identity=78.8321167883212, Blast_Score=420, Evalue=1e-119,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_THIDA (Q3SJI4)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314978.1
- ProteinModelPortal:   Q3SJI4
- SMR:   Q3SJI4
- STRING:   Q3SJI4
- GeneID:   3673309
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1220
- NMPDR:   fig|292415.3.peg.1240
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- PhylomeDB:   Q3SJI4
- ProtClustDB:   PRK11830
- BioCyc:   TDEN292415:TBD_1220-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29717; Mature: 29717

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 105-105 BINDING 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQELQPIIEEAFERRADITPRNATPQVKDAVMAVIDLLDMGQLRVAERTDGQNWTTNQWV
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
KKAVLLSFRLEDNAFIKGGYTNYYDKVPSKFADFNSKDFREGGFRVVPPAAARKGSYIGK
HHHHHEEEEECCCCEEECCCCHHHHHHHHHHHCCCCCHHHCCCCEEECCHHHCCCCCCCC
NVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPVQANPTIIG
CEEEECCEEEECEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEC
DNCFIGARSEVVEGVIVEDNCVISMGVYIGQSTKIYDRETGEIHYGRVPAGSVVVSGNLP
CCEEECCHHHHHCCEEECCCEEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEEECCCC
SKDGSYSLYCAVIVKKVDAKTLSKVGINELLRGI
CCCCCEEEEEEEEHHHHHHHHHHHHCHHHHHHCC
>Mature Secondary Structure
MQELQPIIEEAFERRADITPRNATPQVKDAVMAVIDLLDMGQLRVAERTDGQNWTTNQWV
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
KKAVLLSFRLEDNAFIKGGYTNYYDKVPSKFADFNSKDFREGGFRVVPPAAARKGSYIGK
HHHHHEEEEECCCCEEECCCCHHHHHHHHHHHCCCCCHHHCCCCEEECCHHHCCCCCCCC
NVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPVQANPTIIG
CEEEECCEEEECEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEC
DNCFIGARSEVVEGVIVEDNCVISMGVYIGQSTKIYDRETGEIHYGRVPAGSVVVSGNLP
CCEEECCHHHHHCCEEECCCEEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEEECCCC
SKDGSYSLYCAVIVKKVDAKTLSKVGINELLRGI
CCCCCEEEEEEEEHHHHHHHHHHHHCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA