Click here to switch to the map view.

The map label for this gene is paaE [H]

Identifier: 74317122

GI number: 74317122

Start: 1162880

End: 1163584

Strand: Reverse

Name: paaE [H]

Synonym: Tbd_1104

Alternate gene names: 74317122

Gene position: 1163584-1162880 (Counterclockwise)

Preceding gene: 74317123

Following gene: 74317121

Centisome position: 39.99

GC content: 66.38

Gene sequence:

>705_bases
TTGCACGTCTTTGAAGCCGAGATCGCGGCAGTCGTCGCCGCCACCCCCCAGATACGTGTTCTCCGCCTCGCCGTCGCCGA
CCCCGGCTTCCGCTTCCTGCCCGGGCAGTGGGTCGATCTGAGCGTCGATGTCGACGGCGCCAGGCACACGTCCGGTTACT
CGATCACGACCTCGCCGCTGCATCCCGGCACGATCGAACTCGCCGTCAAGGCGAGCGCGCGGCATCCGCTCGCGCGTTGG
GTTCACGACGAGGCCGCGCCGGGTGACCGCGTGCGCGTGAGCCAGGGCCAGGGGCCGTTCGTCTACCTGCCCGAGATGAG
CGACAACGTCGTGCTGATCGGCGGCGGCGTGGGCATCACGCCGATGCTCTCGATCTTTCGCCACGTCCGCGACGCCGGAC
TGGGGACGCAGGCGCACCTGGTCTACAGCGTATCGGACAGTCGCGAAATCCTCTTCCGCGACGAACTCGAAGCCGCGGTC
CGCAACCACCGCAACCTGCATCTCAGCATCACGGTCACCCAACCCGATCCGGCGTGGCATGGTCTGACCGGCCGCATCGA
TCCGGTCAAGCTGCATGCGCTCGACGTGCCGGACGATACGCTCTATTACCTGTGCGGGCCGCGCGGAATGGTCGAAGACA
TGAGCACGCTGCTCCACGACCTCGGCGTGCCGATGAACCGGATCATCTTCGAAAAATGGTGGTAG

Upstream 100 bases:

>100_bases
CTCGCACCTCGGCCACGTCTTCCCCGACGGGCCGCCGCCCACCGGTCTGCGCTACTGCATCAATTCGGCGTCGCTCAGTT
TTCACCCGAAGGACTGAGCC

Downstream 100 bases:

>100_bases
GCGTTTTCGACCATTAAACTCTCAGGGTTGTCTGTGTATGGTTCCGCAACCACAAGGAGACTCTGATATGCGCCTACTTC
CGCTGCTCGCCACCCTCGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MHVFEAEIAAVVAATPQIRVLRLAVADPGFRFLPGQWVDLSVDVDGARHTSGYSITTSPLHPGTIELAVKASARHPLARW
VHDEAAPGDRVRVSQGQGPFVYLPEMSDNVVLIGGGVGITPMLSIFRHVRDAGLGTQAHLVYSVSDSREILFRDELEAAV
RNHRNLHLSITVTQPDPAWHGLTGRIDPVKLHALDVPDDTLYYLCGPRGMVEDMSTLLHDLGVPMNRIIFEKWW

Sequences:

>Translated_234_residues
MHVFEAEIAAVVAATPQIRVLRLAVADPGFRFLPGQWVDLSVDVDGARHTSGYSITTSPLHPGTIELAVKASARHPLARW
VHDEAAPGDRVRVSQGQGPFVYLPEMSDNVVLIGGGVGITPMLSIFRHVRDAGLGTQAHLVYSVSDSREILFRDELEAAV
RNHRNLHLSITVTQPDPAWHGLTGRIDPVKLHALDVPDDTLYYLCGPRGMVEDMSTLLHDLGVPMNRIIFEKWW
>Mature_234_residues
MHVFEAEIAAVVAATPQIRVLRLAVADPGFRFLPGQWVDLSVDVDGARHTSGYSITTSPLHPGTIELAVKASARHPLARW
VHDEAAPGDRVRVSQGQGPFVYLPEMSDNVVLIGGGVGITPMLSIFRHVRDAGLGTQAHLVYSVSDSREILFRDELEAAV
RNHRNLHLSITVTQPDPAWHGLTGRIDPVKLHALDVPDDTLYYLCGPRGMVEDMSTLLHDLGVPMNRIIFEKWW

Specific function: May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI19923907, Length=256, Percent_Identity=35.546875, Blast_Score=127, Evalue=6e-30,
Organism=Escherichia coli, GI1787658, Length=238, Percent_Identity=32.3529411764706, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788903, Length=233, Percent_Identity=27.8969957081545, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788104, Length=236, Percent_Identity=25.4237288135593, Blast_Score=71, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323510, Length=226, Percent_Identity=24.3362831858407, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR011884
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25801; Mature: 25801

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVFEAEIAAVVAATPQIRVLRLAVADPGFRFLPGQWVDLSVDVDGARHTSGYSITTSPL
CEEEHHHHEEEEECCCCEEEEEEEECCCCCEECCCCEEEEEEECCCCCCCCCCEEEECCC
HPGTIELAVKASARHPLARWVHDEAAPGDRVRVSQGQGPFVYLPEMSDNVVLIGGGVGIT
CCCEEEEEEEECCCCHHHHHHCCCCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCHH
PMLSIFRHVRDAGLGTQAHLVYSVSDSREILFRDELEAAVRNHRNLHLSITVTQPDPAWH
HHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEHHHHHHHHHCCCEEEEEEEEECCCCCCC
GLTGRIDPVKLHALDVPDDTLYYLCGPRGMVEDMSTLLHDLGVPMNRIIFEKWW
CCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHEEECCC
>Mature Secondary Structure
MHVFEAEIAAVVAATPQIRVLRLAVADPGFRFLPGQWVDLSVDVDGARHTSGYSITTSPL
CEEEHHHHEEEEECCCCEEEEEEEECCCCCEECCCCEEEEEEECCCCCCCCCCEEEECCC
HPGTIELAVKASARHPLARWVHDEAAPGDRVRVSQGQGPFVYLPEMSDNVVLIGGGVGIT
CCCEEEEEEEECCCCHHHHHHCCCCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCHH
PMLSIFRHVRDAGLGTQAHLVYSVSDSREILFRDELEAAVRNHRNLHLSITVTQPDPAWH
HHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEHHHHHHHHHCCCEEEEEEEEECCCCCCC
GLTGRIDPVKLHALDVPDDTLYYLCGPRGMVEDMSTLLHDLGVPMNRIIFEKWW
CCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]