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The map label for this gene is tbpA [C]

Identifier: 74317008

GI number: 74317008

Start: 1056286

End: 1057335

Strand: Reverse

Name: tbpA [C]

Synonym: Tbd_0990

Alternate gene names: 74317008

Gene position: 1057335-1056286 (Counterclockwise)

Preceding gene: 74317009

Following gene: 74317007

Centisome position: 36.34

GC content: 62.67

Gene sequence:

>1050_bases
ATGCCGCACAATCCCTTTCACCCCAAGGAAACGAAGATGAAATCGACGCTCACCCGGCTCCTCTCCGTCGTAGCCCTCGG
CCTCGCCTCGCTGCCTGCCCTGGCAGAGGAAGTCGTCGTCTACTCGGCGCGCAACGAGCAGCTGATCAAGCCCCTGTTCG
ACGCTTACACGCGCGAGACCGGCGTACAAGTCAAGTTCGTGACCGACAAGGAAGGCCCCCTGATGGCGCGCCTCAAGGCG
GAGGGCAAGAACACGCCGGCCGACGTGCTGCTGACGGTCGACGCCGGCAACCTGTGGCAGGCGTCGGAAGAAGGCCTGCT
GCGCCCGATCAAGTCGAAGACCCTGCAGACCAACGTGCCGGCCCACCTGCGCGACCCCGACAACGAGTGGTTCGGCCTGT
CGGTGCGCGCGCGCACGATGGTCTACAACACCGGCAAGGTGAAGCCCGGCGAATTGTCGACCTATGAAGACCTCGCCAAC
CCCAAATGGAAAGGCCGCCTCTGCCTGCGCACCTCGAAGAAGGTCTACAACCAGAGCCTGGTCGCGATGATGATCACCGA
ATACGGCGAGGACAAGACCGAAGACATGGTGCGCGGCTGGGTCGCCAACCTCGCGACCTCGCCCTTCCCCGACGACACCA
AGGCAATGGAAGCCGTCGCCGCCGGGCAATGTGACGTCACGCTCGTCAACACCTATTACTTCGGTCGCCTGATGGACAAG
AAGTCCGACCTGCCGCTCGCGATCTTCTGGCCGAACCAGAATCTCAAGAACAAGGCCGCCGGCGTGCACGTCAACGTCTC
GGGTGCCGGCGTCACACGCCATGCGAGAAACCCGGCGGGGGCACAAAAGCTGATCGAGTGGCTGTCGTCGGAAAAGGCGC
AGAACCAGTTCGCCGACGTCAACCTCGAATACCCGGTCAACCCGAAGGTCTCGCCCGACCAGAAGGTCGCCGCCTGGGGC
AACTTCAAGCAGAACCTCATCAACGTGAAGGACGCTGGCAGCCTGCAGGCCAAGGCCGTAAAATTGATGGACCGCGCTGG
CTACAAATAA

Upstream 100 bases:

>100_bases
TGAAGCTCGACACGCATTTCGAAGGGGAACTGCGCCTTGTGTTCCAGTTCGAGCACCGCTGAACGGCATATTATTGATAA
CCGTTCTCATTAGTAGTAGG

Downstream 100 bases:

>100_bases
ACACACCTTGTCCGAAACCGCTGCAGCACCTGCAAAAACGCCCCCCGCGGGCGTTTTTGTTTTCCCTGCGTCCCGCCGGC
GGGCAAGCGGCTGGATGCTG

Product: ABC transporter iron binding protein

Products: ADP; phosphate; thiamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MPHNPFHPKETKMKSTLTRLLSVVALGLASLPALAEEVVVYSARNEQLIKPLFDAYTRETGVQVKFVTDKEGPLMARLKA
EGKNTPADVLLTVDAGNLWQASEEGLLRPIKSKTLQTNVPAHLRDPDNEWFGLSVRARTMVYNTGKVKPGELSTYEDLAN
PKWKGRLCLRTSKKVYNQSLVAMMITEYGEDKTEDMVRGWVANLATSPFPDDTKAMEAVAAGQCDVTLVNTYYFGRLMDK
KSDLPLAIFWPNQNLKNKAAGVHVNVSGAGVTRHARNPAGAQKLIEWLSSEKAQNQFADVNLEYPVNPKVSPDQKVAAWG
NFKQNLINVKDAGSLQAKAVKLMDRAGYK

Sequences:

>Translated_349_residues
MPHNPFHPKETKMKSTLTRLLSVVALGLASLPALAEEVVVYSARNEQLIKPLFDAYTRETGVQVKFVTDKEGPLMARLKA
EGKNTPADVLLTVDAGNLWQASEEGLLRPIKSKTLQTNVPAHLRDPDNEWFGLSVRARTMVYNTGKVKPGELSTYEDLAN
PKWKGRLCLRTSKKVYNQSLVAMMITEYGEDKTEDMVRGWVANLATSPFPDDTKAMEAVAAGQCDVTLVNTYYFGRLMDK
KSDLPLAIFWPNQNLKNKAAGVHVNVSGAGVTRHARNPAGAQKLIEWLSSEKAQNQFADVNLEYPVNPKVSPDQKVAAWG
NFKQNLINVKDAGSLQAKAVKLMDRAGYK
>Mature_348_residues
PHNPFHPKETKMKSTLTRLLSVVALGLASLPALAEEVVVYSARNEQLIKPLFDAYTRETGVQVKFVTDKEGPLMARLKAE
GKNTPADVLLTVDAGNLWQASEEGLLRPIKSKTLQTNVPAHLRDPDNEWFGLSVRARTMVYNTGKVKPGELSTYEDLANP
KWKGRLCLRTSKKVYNQSLVAMMITEYGEDKTEDMVRGWVANLATSPFPDDTKAMEAVAAGQCDVTLVNTYYFGRLMDKK
SDLPLAIFWPNQNLKNKAAGVHVNVSGAGVTRHARNPAGAQKLIEWLSSEKAQNQFADVNLEYPVNPKVSPDQKVAAWGN
FKQNLINVKDAGSLQAKAVKLMDRAGYK

Specific function: Part Of The Binding-Protein-Dependent Transport System Tbpa-Thipq For Thiamine And Tpp. [C]

COG id: COG1840

COG function: function code P; ABC-type Fe3+ transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 38628; Mature: 38496

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHNPFHPKETKMKSTLTRLLSVVALGLASLPALAEEVVVYSARNEQLIKPLFDAYTRET
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCC
GVQVKFVTDKEGPLMARLKAEGKNTPADVLLTVDAGNLWQASEEGLLRPIKSKTLQTNVP
CCEEEEEECCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCEECCCC
AHLRDPDNEWFGLSVRARTMVYNTGKVKPGELSTYEDLANPKWKGRLCLRTSKKVYNQSL
CCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
VAMMITEYGEDKTEDMVRGWVANLATSPFPDDTKAMEAVAAGQCDVTLVNTYYFGRLMDK
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHCC
KSDLPLAIFWPNQNLKNKAAGVHVNVSGAGVTRHARNPAGAQKLIEWLSSEKAQNQFADV
CCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCE
NLEYPVNPKVSPDQKVAAWGNFKQNLINVKDAGSLQAKAVKLMDRAGYK
EEECCCCCCCCCCCCCHHHCCHHHHEECCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PHNPFHPKETKMKSTLTRLLSVVALGLASLPALAEEVVVYSARNEQLIKPLFDAYTRET
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCC
GVQVKFVTDKEGPLMARLKAEGKNTPADVLLTVDAGNLWQASEEGLLRPIKSKTLQTNVP
CCEEEEEECCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCEECCCC
AHLRDPDNEWFGLSVRARTMVYNTGKVKPGELSTYEDLANPKWKGRLCLRTSKKVYNQSL
CCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
VAMMITEYGEDKTEDMVRGWVANLATSPFPDDTKAMEAVAAGQCDVTLVNTYYFGRLMDK
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHCC
KSDLPLAIFWPNQNLKNKAAGVHVNVSGAGVTRHARNPAGAQKLIEWLSSEKAQNQFADV
CCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCE
NLEYPVNPKVSPDQKVAAWGNFKQNLINVKDAGSLQAKAVKLMDRAGYK
EEECCCCCCCCCCCCCHHHCCHHHHEECCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; thiamine [Periplasm]; H2O [C]

Specific reaction: ATP + thiamine [Periplasm] + H2O = ADP + phosphate + thiamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]