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The map label for this gene is ubiG

Identifier: 74316964

GI number: 74316964

Start: 1006439

End: 1007137

Strand: Reverse

Name: ubiG

Synonym: Tbd_0946

Alternate gene names: 74316964

Gene position: 1007137-1006439 (Counterclockwise)

Preceding gene: 74316965

Following gene: 74316963

Centisome position: 34.61

GC content: 65.38

Gene sequence:

>699_bases
ATGAGCAACGTCGACGCTGCCGAAATCGCCAAGTTTTCCGAGCTTGCCCACCGCTGGTGGGACCCGAACTCCGAATTCAA
GCCGCTGCACGAAATCAACCCGCTGCGCCTGAGATGGGTCGACACGCGCGCGCCGCTCGCCGGCAAGAAAGTGCTCGACG
TCGGCTGCGGCGGCGGCATCCTCGCCGAAGCGATGGCCGGTGTCGGCGCGACCGTGAGCGGAATCGACCTCTCCGAGAAG
GCGCTCAAGGTTGCCCGCCTCCATCTCTACGAATCCGGCAAGAGCGTCGACTACGAACTCGTCTCGGCCGAAGACTACGC
CGCCGCCCACCCCGGCGAATTCGACGTCGTGACCTGCATGGAAATGCTCGAACACGTTCCCGACCCCGCCTCGGTCGTCG
CCGCCTGCGCGCGCCTCGTCAAACCGGGCGGCTGGGTGTTCTTCTCGACGCTCAACCGCAACGCCAAGAGCTACCTGCTC
GCCGTGGTCGGCGCCGAATACATTCTCAAGCTGCTGCCGCGCGGCACCCACGACTACGCCAAGTTCATCAAGCCCGCCGA
ACTCGCGCGGATGGCGCGCGAAGCCGGGCTCGAAACCGAGGAGCTGACCGGCATGACCTACAACCCGCTGACCAAGGTTT
ACCGGCTCGAAGCCGACACCGACGTCAACTACCTGATGGCGACCCGCCGTGAAGCCTGA

Upstream 100 bases:

>100_bases
AGCCCAAACTCAGGGAACGCAGCCTGGTCGGGCTCGACGCCGACGACCTCGCCGCCCGCGCCGTCTACTGGCGCACCAAA
CTCACCGCAGAAGGACAGTC

Downstream 100 bases:

>100_bases
GCACGCGCGGCTCGACGGCATCCGCGCAGTCCTGTTCGACCTCGACGGCACGCTGGTCGACACGGCGCCCGACCTCGGCA
ACGCGCTCAACCTGCAGCGC

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSNVDAAEIAKFSELAHRWWDPNSEFKPLHEINPLRLRWVDTRAPLAGKKVLDVGCGGGILAEAMAGVGATVSGIDLSEK
ALKVARLHLYESGKSVDYELVSAEDYAAAHPGEFDVVTCMEMLEHVPDPASVVAACARLVKPGGWVFFSTLNRNAKSYLL
AVVGAEYILKLLPRGTHDYAKFIKPAELARMAREAGLETEELTGMTYNPLTKVYRLEADTDVNYLMATRREA

Sequences:

>Translated_232_residues
MSNVDAAEIAKFSELAHRWWDPNSEFKPLHEINPLRLRWVDTRAPLAGKKVLDVGCGGGILAEAMAGVGATVSGIDLSEK
ALKVARLHLYESGKSVDYELVSAEDYAAAHPGEFDVVTCMEMLEHVPDPASVVAACARLVKPGGWVFFSTLNRNAKSYLL
AVVGAEYILKLLPRGTHDYAKFIKPAELARMAREAGLETEELTGMTYNPLTKVYRLEADTDVNYLMATRREA
>Mature_231_residues
SNVDAAEIAKFSELAHRWWDPNSEFKPLHEINPLRLRWVDTRAPLAGKKVLDVGCGGGILAEAMAGVGATVSGIDLSEKA
LKVARLHLYESGKSVDYELVSAEDYAAAHPGEFDVVTCMEMLEHVPDPASVVAACARLVKPGGWVFFSTLNRNAKSYLLA
VVGAEYILKLLPRGTHDYAKFIKPAELARMAREAGLETEELTGMTYNPLTKVYRLEADTDVNYLMATRREA

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=238, Percent_Identity=34.8739495798319, Blast_Score=171, Evalue=7e-43,
Organism=Escherichia coli, GI1788564, Length=230, Percent_Identity=61.7391304347826, Blast_Score=294, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI115533050, Length=237, Percent_Identity=32.4894514767932, Blast_Score=133, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6324476, Length=279, Percent_Identity=30.4659498207885, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI281365311, Length=244, Percent_Identity=33.6065573770492, Blast_Score=151, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24585589, Length=203, Percent_Identity=36.9458128078818, Blast_Score=140, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_THIDA (Q3SK91)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314704.1
- ProteinModelPortal:   Q3SK91
- SMR:   Q3SK91
- STRING:   Q3SK91
- GeneID:   3672738
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0946
- NMPDR:   fig|292415.3.peg.536
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- PhylomeDB:   Q3SK91
- ProtClustDB:   PRK05134
- BioCyc:   TDEN292415:TBD_0946-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 25482; Mature: 25351

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVDAAEIAKFSELAHRWWDPNSEFKPLHEINPLRLRWVDTRAPLAGKKVLDVGCGGGI
CCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEEEECCCCCCCCCEEEEECCCCHH
LAEAMAGVGATVSGIDLSEKALKVARLHLYESGKSVDYELVSAEDYAAAHPGEFDVVTCM
HHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHH
EMLEHVPDPASVVAACARLVKPGGWVFFSTLNRNAKSYLLAVVGAEYILKLLPRGTHDYA
HHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
KFIKPAELARMAREAGLETEELTGMTYNPLTKVYRLEADTDVNYLMATRREA
HHCCHHHHHHHHHHHCCCHHHHCCCCCCCHHHHEEECCCCCCHHHHHHCCCC
>Mature Secondary Structure 
SNVDAAEIAKFSELAHRWWDPNSEFKPLHEINPLRLRWVDTRAPLAGKKVLDVGCGGGI
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEEEECCCCCCCCCEEEEECCCCHH
LAEAMAGVGATVSGIDLSEKALKVARLHLYESGKSVDYELVSAEDYAAAHPGEFDVVTCM
HHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHH
EMLEHVPDPASVVAACARLVKPGGWVFFSTLNRNAKSYLLAVVGAEYILKLLPRGTHDYA
HHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
KFIKPAELARMAREAGLETEELTGMTYNPLTKVYRLEADTDVNYLMATRREA
HHCCHHHHHHHHHHHCCCHHHHCCCCCCCHHHHEEECCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA