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The map label for this gene is ackA [H]

Identifier: 74316850

GI number: 74316850

Start: 878966

End: 880057

Strand: Direct

Name: ackA [H]

Synonym: Tbd_0832

Alternate gene names: 74316850

Gene position: 878966-880057 (Clockwise)

Preceding gene: 74316849

Following gene: 74316851

Centisome position: 30.21

GC content: 72.07

Gene sequence:

>1092_bases
ATGGGCGCGCTAACCCGCAGCGTACTGACGCTCAACAGCGGCTCGTCGAGCCTCAAGGTGAGTCTGTTCCGCGCCGACGG
CACGCGCAGCAACTGGCATTACCGCGCGCGCAGCGGCGCCGACGACGAGGCCTTCGCCGGCCTGCTGCGCGACCTCGACG
GCGAGGCGCCGGACGCGGTCGGGCACCGCTTCGTCCACGGCGGCGAGATTGCCGAGGCCGCCCGCCTGCTCGACGACGCC
GAGCTCGCGCGATTGGGTCAACTCGTCCCGCTCGCGCCGCTGCACCTGCCCGGCAACCTGCACGGCGTCGAATGGTGCCG
CGCGCACTTCGATCTGCCGCAGGTCGCGTGCTTCGATACCGCCTTCCACCACACGCTGCCCGAACTCGCGCGCCGGTTGC
CGATCCCGCGCGAACTCGGGCTGCGACGCTACGGTTTCCACGGCCTCAACTACAGCTACGTCGCCGCGCGCCTGCCCGCG
CTGCTCGGCGCGGCGGCGCACGGGCGCGTCGTCGTCGCCCATCTCGGTTCCGGCGCGAGCCTGTGCCTGCTCGAAAATCT
GCGCTCGGCCGACACGACCATGGGCTGGTCGCCGGCAGGCGGCATCCCGATGGCGACGCGCAGCGGCGACCTCGACCCCG
GCGTCATGCTCGAACTCGCCGGGCGCTTCGACGGCGAGGCCTTGCGCGAACTCGTCTACCGGCGGATGGGACTTCTCGCC
CTGTCGGATGGCGAAAGCGCCGAAATGTCGGCCCTGCTCGCAAGCGAAAGCGCGGCGGCGGCGTTCGCGGTCGACTACTT
CTGCCGCCAGGTGCGTGCCGCGATCGGCGCCTTCGCCGCGAAGAGCGGGGGCATCGACGCGTTGGTGTTCACCGGCGGCA
TCGGCGAGCACGCGCCCGAGGTGCGCGCCCGCGTCTGCGCGCCGCTCGGCTTCCTCGGTTTCGCGCTCGACGCCGCTGCG
AACGAAGCCGGGCGCGAGGCGCTTCGTGCGCCGGGGTCGAAGCCGGTGCTGAAGATCGCGGCCGGCGAGGAGGACGTCAT
ACGGGACGAGGTGGAACGCGTACTCGACGGCGCACCGTGCCCTGAACCCTAG

Upstream 100 bases:

>100_bases
AGGCGGCGCACCTGCAGCAGCAGATGCTCGACAAGCTCGGCGCGCACACGCAATACATCCACGCCCACGGCGAGGACATG
CCCGAGATCCGGGACTGGAA

Downstream 100 bases:

>100_bases
CCCCGCGGGCTCCTTCGCGCGCCGGCGCCCGAGCCTCCCCGGTCTTGGGCGCGAGCCCGCGTGCCCCTAGAATTGAAAAG
TGCCCACCTCCACCGCGCCT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGALTRSVLTLNSGSSSLKVSLFRADGTRSNWHYRARSGADDEAFAGLLRDLDGEAPDAVGHRFVHGGEIAEAARLLDDA
ELARLGQLVPLAPLHLPGNLHGVEWCRAHFDLPQVACFDTAFHHTLPELARRLPIPRELGLRRYGFHGLNYSYVAARLPA
LLGAAAHGRVVVAHLGSGASLCLLENLRSADTTMGWSPAGGIPMATRSGDLDPGVMLELAGRFDGEALRELVYRRMGLLA
LSDGESAEMSALLASESAAAAFAVDYFCRQVRAAIGAFAAKSGGIDALVFTGGIGEHAPEVRARVCAPLGFLGFALDAAA
NEAGREALRAPGSKPVLKIAAGEEDVIRDEVERVLDGAPCPEP

Sequences:

>Translated_363_residues
MGALTRSVLTLNSGSSSLKVSLFRADGTRSNWHYRARSGADDEAFAGLLRDLDGEAPDAVGHRFVHGGEIAEAARLLDDA
ELARLGQLVPLAPLHLPGNLHGVEWCRAHFDLPQVACFDTAFHHTLPELARRLPIPRELGLRRYGFHGLNYSYVAARLPA
LLGAAAHGRVVVAHLGSGASLCLLENLRSADTTMGWSPAGGIPMATRSGDLDPGVMLELAGRFDGEALRELVYRRMGLLA
LSDGESAEMSALLASESAAAAFAVDYFCRQVRAAIGAFAAKSGGIDALVFTGGIGEHAPEVRARVCAPLGFLGFALDAAA
NEAGREALRAPGSKPVLKIAAGEEDVIRDEVERVLDGAPCPEP
>Mature_362_residues
GALTRSVLTLNSGSSSLKVSLFRADGTRSNWHYRARSGADDEAFAGLLRDLDGEAPDAVGHRFVHGGEIAEAARLLDDAE
LARLGQLVPLAPLHLPGNLHGVEWCRAHFDLPQVACFDTAFHHTLPELARRLPIPRELGLRRYGFHGLNYSYVAARLPAL
LGAAAHGRVVVAHLGSGASLCLLENLRSADTTMGWSPAGGIPMATRSGDLDPGVMLELAGRFDGEALRELVYRRMGLLAL
SDGESAEMSALLASESAAAAFAVDYFCRQVRAAIGAFAAKSGGIDALVFTGGIGEHAPEVRARVCAPLGFLGFALDAAAN
EAGREALRAPGSKPVLKIAAGEEDVIRDEVERVLDGAPCPEP

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=401, Percent_Identity=32.4189526184539, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI145693184, Length=350, Percent_Identity=34.5714285714286, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 38298; Mature: 38167

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS01075 ACETATE_KINASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALTRSVLTLNSGSSSLKVSLFRADGTRSNWHYRARSGADDEAFAGLLRDLDGEAPDAV
CCCHHCEEEEECCCCCCEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCHHH
GHRFVHGGEIAEAARLLDDAELARLGQLVPLAPLHLPGNLHGVEWCRAHFDLPQVACFDT
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHH
AFHHTLPELARRLPIPRELGLRRYGFHGLNYSYVAARLPALLGAAAHGRVVVAHLGSGAS
HHHHHHHHHHHHCCCCHHHCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
LCLLENLRSADTTMGWSPAGGIPMATRSGDLDPGVMLELAGRFDGEALRELVYRRMGLLA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCEEE
LSDGESAEMSALLASESAAAAFAVDYFCRQVRAAIGAFAAKSGGIDALVFTGGIGEHAPE
ECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHH
VRARVCAPLGFLGFALDAAANEAGREALRAPGSKPVLKIAAGEEDVIRDEVERVLDGAPC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
PEP
CCC
>Mature Secondary Structure 
GALTRSVLTLNSGSSSLKVSLFRADGTRSNWHYRARSGADDEAFAGLLRDLDGEAPDAV
CCHHCEEEEECCCCCCEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCHHH
GHRFVHGGEIAEAARLLDDAELARLGQLVPLAPLHLPGNLHGVEWCRAHFDLPQVACFDT
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHH
AFHHTLPELARRLPIPRELGLRRYGFHGLNYSYVAARLPALLGAAAHGRVVVAHLGSGAS
HHHHHHHHHHHHCCCCHHHCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
LCLLENLRSADTTMGWSPAGGIPMATRSGDLDPGVMLELAGRFDGEALRELVYRRMGLLA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCEEE
LSDGESAEMSALLASESAAAAFAVDYFCRQVRAAIGAFAAKSGGIDALVFTGGIGEHAPE
ECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHH
VRARVCAPLGFLGFALDAAANEAGREALRAPGSKPVLKIAAGEEDVIRDEVERVLDGAPC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
PEP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA