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The map label for this gene is norD [H]

Identifier: 74316843

GI number: 74316843

Start: 866976

End: 869000

Strand: Direct

Name: norD [H]

Synonym: Tbd_0825

Alternate gene names: 74316843

Gene position: 866976-869000 (Clockwise)

Preceding gene: 74316842

Following gene: 74316849

Centisome position: 29.79

GC content: 72.54

Gene sequence:

>2025_bases
ATGCCCGAGGCGGAAGAACTCATCATCGATGCCGCGCGCCATGCCGGCACCGCGGTGCACGGATTCTGGCGGCGCCGCCA
CGCCCCGCCGCCGACGCCGACGGTATTCCTGCGCGACGTGCGCACGCGCCTCGAGATGCTGATCGACGCCGTGCTCGGTT
GCGAGCTGCCGGTGCGGGCGGCGCAGGCGGCCGCGCCGATGCCGCTTCTGCGCAGGCTGTTCACGCGCGGTGGACGGAAG
ACGGCGGCCGCCGGACCGCTTCCGGCGACCGACGGCACGGCGGTTTTCCTGCCGCCGAGCCTTCCCGTATCGCCGCCGGC
GTCGGCGGCGTTCACCGACGACTACTGCCTGCTCGCGCTGCTGCAGGCGCTGCATCACCTGCGCGGAAGCGCAGGCGAAA
TCGCGCGCCTGGAGTCGGACCTCGCGCGCGACCTGTACCTGATCGCCGAAGCCGCGGCGGTCGACCACCGGCTGCGCCGG
CTCATGCCGGGATGGTCGCAGGCGCTCGACGCGCTTTACGTGCGGATGGACCGCGCGCTTGCGCAGCGCCGCCTGCGGGA
CGCGCTCGAGGCCGACGTCGCGGCGCGTTACCGGAATTTCCTGCGTGGCCGCGCGGGCGCGGAAACGCTGCACGCGAATC
CGGCCGCGGCGCTCGACTGGGCGAATGCACAGGCGCGCGCCCTGCGTCTGCGCGTGCCTGCCAGGCGCTATGTCGCCTGG
CTCGGCGACCTCGTCGTCGGCCGCCTGCTGCCACCCGAAGGCGCGCCGCGGGCGCGTGTGCGCGCATCCTCGAAGGCGGC
GGCGGCCGCGGACGCGCGGGCCGGCGCGCGCACGGCCTCGCTCGTGCGGCGTCCGCGCGTGCGCGACGGCCGCGACGAGG
ACGATGCGAAACCGGGCGTATCGATGGTCCAGACCTCCGAGCCGCATCCGCACGCCGAGGATCCCTTCGGCCTCAACCGT
CCGGAAGACCAGGAGCCGGAAGACGACTTGGGGGGCGCGGCGGAGTCGCTGGCCGAAATGGAAGAGGCGCGGCTGGTCCA
CAGCCCCGGCGCTGCGCGCGAAGCCTTCGAGGCAAGCGATCCGCCGCCACGGCTCGAAAGCGCGGCGGACACCGCACTGC
CGCCCTGTGCATTCAGCTACCCGGAATGGGATTGCCGCACGAGTCGTTACCGTGAAAACGCTGTTGCACTTTTCTCGCAT
CCGGCGAAACCGGGCGGCGCGAAATGGGTCGCCGACGCGTTGCAGCGCAACGCCGGCCTGCTCGCACAGATCCGCCGGCG
GCTCGGCGCGATTCGTCCCGACCGCACGATCCTGCGCGGGCAGACCGCGGGGGACGAGATCGACCTCGACGCGGTCGTCG
CCGCGCGGGGCGAGCGCCGGGCCGGCGCGACAGGCGACGCGCGCTTCTACCGCTCCCGTCGTCCGGCGCCGCGCACGCTC
GCGCTTGTGCTCCTGGTCGACGCGAGCGCGTCGACCGACGCATGGGTGACGCGCAAGGACCGCGTCATCGACATCGAGAA
GGAGGCGGCGCTGCTCGCCGCGGCGGGGCTCGAGACCTTGCGAACGCGCTTCGCGGTGCTCGCGTTTTCGGGCGAAGGCC
CGGCCGGCGTGCAGATACGCGAGATCAAGCGTTTCGACGAGACCTGGGATGCAAGCGCACAGCGTCGCCTCGCCGGCCTC
GAGCCCGACCGCTACACCCGGCTCGGCGCCGCCCTACGCCACGCCAACGCCTTGCTCGCGGCGTGCGCGGCTGACCACCG
GCTGTTGCTACTTTTGTCGGACGGGCGGCCCAACGACTGCGACCGCTACGCGAGCCGCTACGGCATCGAAGACGCGCGCC
AAGCGCTCACCGAGGCGCGGCTCAAGCGCATTTCGCCCTACTGCTTCACGGTCGACCGCGCCGGCGGCAGTTATCTGCCG
ACGATTTTCGGCAGCGAGGGCTACACAGTGGTGCAGCACCCGCAACAGCTGCCGGTCGCGTTCATCAACTGGCTGCGGCG
CGCGGCGCGCGTGTGCATGCGCTAG

Upstream 100 bases:

>100_bases
GCGCCGCGCCTGCGAGGTCGCGATCGCCGACGCGCTGACCGACGACCCGCTGCTGCTCGGTACCCTCGGCGATCTGATCG
CCGGCAGCTTTCCCTGAGCA

Downstream 100 bases:

>100_bases
ACGCGCCGCTGGCTCAGCCTTCGTCGTAGCCTTCGTCGACCGGGTTGTCGACCAGATGGAACGGATGGTCGATCGGCATA
TCCATGAATTCCTTGCGCGT

Product: nitric oxide reductase activase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MPEAEELIIDAARHAGTAVHGFWRRRHAPPPTPTVFLRDVRTRLEMLIDAVLGCELPVRAAQAAAPMPLLRRLFTRGGRK
TAAAGPLPATDGTAVFLPPSLPVSPPASAAFTDDYCLLALLQALHHLRGSAGEIARLESDLARDLYLIAEAAAVDHRLRR
LMPGWSQALDALYVRMDRALAQRRLRDALEADVAARYRNFLRGRAGAETLHANPAAALDWANAQARALRLRVPARRYVAW
LGDLVVGRLLPPEGAPRARVRASSKAAAAADARAGARTASLVRRPRVRDGRDEDDAKPGVSMVQTSEPHPHAEDPFGLNR
PEDQEPEDDLGGAAESLAEMEEARLVHSPGAAREAFEASDPPPRLESAADTALPPCAFSYPEWDCRTSRYRENAVALFSH
PAKPGGAKWVADALQRNAGLLAQIRRRLGAIRPDRTILRGQTAGDEIDLDAVVAARGERRAGATGDARFYRSRRPAPRTL
ALVLLVDASASTDAWVTRKDRVIDIEKEAALLAAAGLETLRTRFAVLAFSGEGPAGVQIREIKRFDETWDASAQRRLAGL
EPDRYTRLGAALRHANALLAACAADHRLLLLLSDGRPNDCDRYASRYGIEDARQALTEARLKRISPYCFTVDRAGGSYLP
TIFGSEGYTVVQHPQQLPVAFINWLRRAARVCMR

Sequences:

>Translated_674_residues
MPEAEELIIDAARHAGTAVHGFWRRRHAPPPTPTVFLRDVRTRLEMLIDAVLGCELPVRAAQAAAPMPLLRRLFTRGGRK
TAAAGPLPATDGTAVFLPPSLPVSPPASAAFTDDYCLLALLQALHHLRGSAGEIARLESDLARDLYLIAEAAAVDHRLRR
LMPGWSQALDALYVRMDRALAQRRLRDALEADVAARYRNFLRGRAGAETLHANPAAALDWANAQARALRLRVPARRYVAW
LGDLVVGRLLPPEGAPRARVRASSKAAAAADARAGARTASLVRRPRVRDGRDEDDAKPGVSMVQTSEPHPHAEDPFGLNR
PEDQEPEDDLGGAAESLAEMEEARLVHSPGAAREAFEASDPPPRLESAADTALPPCAFSYPEWDCRTSRYRENAVALFSH
PAKPGGAKWVADALQRNAGLLAQIRRRLGAIRPDRTILRGQTAGDEIDLDAVVAARGERRAGATGDARFYRSRRPAPRTL
ALVLLVDASASTDAWVTRKDRVIDIEKEAALLAAAGLETLRTRFAVLAFSGEGPAGVQIREIKRFDETWDASAQRRLAGL
EPDRYTRLGAALRHANALLAACAADHRLLLLLSDGRPNDCDRYASRYGIEDARQALTEARLKRISPYCFTVDRAGGSYLP
TIFGSEGYTVVQHPQQLPVAFINWLRRAARVCMR
>Mature_673_residues
PEAEELIIDAARHAGTAVHGFWRRRHAPPPTPTVFLRDVRTRLEMLIDAVLGCELPVRAAQAAAPMPLLRRLFTRGGRKT
AAAGPLPATDGTAVFLPPSLPVSPPASAAFTDDYCLLALLQALHHLRGSAGEIARLESDLARDLYLIAEAAAVDHRLRRL
MPGWSQALDALYVRMDRALAQRRLRDALEADVAARYRNFLRGRAGAETLHANPAAALDWANAQARALRLRVPARRYVAWL
GDLVVGRLLPPEGAPRARVRASSKAAAAADARAGARTASLVRRPRVRDGRDEDDAKPGVSMVQTSEPHPHAEDPFGLNRP
EDQEPEDDLGGAAESLAEMEEARLVHSPGAAREAFEASDPPPRLESAADTALPPCAFSYPEWDCRTSRYRENAVALFSHP
AKPGGAKWVADALQRNAGLLAQIRRRLGAIRPDRTILRGQTAGDEIDLDAVVAARGERRAGATGDARFYRSRRPAPRTLA
LVLLVDASASTDAWVTRKDRVIDIEKEAALLAAAGLETLRTRFAVLAFSGEGPAGVQIREIKRFDETWDASAQRRLAGLE
PDRYTRLGAALRHANALLAACAADHRLLLLLSDGRPNDCDRYASRYGIEDARQALTEARLKRISPYCFTVDRAGGSYLPT
IFGSEGYTVVQHPQQLPVAFINWLRRAARVCMR

Specific function: Part of the operon norEFCBQD encoding nitric oxide reductase. Essential virulence factor, probably involved in the detoxification of nitric oxide (NO) produced in the macrophages during the innate response against infection [H]

COG id: COG4548

COG function: function code P; Nitric oxide reductase activation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002035 [H]

Pfam domain/function: PF00092 VWA [H]

EC number: NA

Molecular weight: Translated: 73587; Mature: 73456

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEAEELIIDAARHAGTAVHGFWRRRHAPPPTPTVFLRDVRTRLEMLIDAVLGCELPVRA
CCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AQAAAPMPLLRRLFTRGGRKTAAAGPLPATDGTAVFLPPSLPVSPPASAAFTDDYCLLAL
HHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHH
LQALHHLRGSAGEIARLESDLARDLYLIAEAAAVDHRLRRLMPGWSQALDALYVRMDRAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AQRRLRDALEADVAARYRNFLRGRAGAETLHANPAAALDWANAQARALRLRVPARRYVAW
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHCCCCCHHHEEEEECCHHHHHHH
LGDLVVGRLLPPEGAPRARVRASSKAAAAADARAGARTASLVRRPRVRDGRDEDDAKPGV
HHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCC
SMVQTSEPHPHAEDPFGLNRPEDQEPEDDLGGAAESLAEMEEARLVHSPGAAREAFEASD
CEEECCCCCCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
PPPRLESAADTALPPCAFSYPEWDCRTSRYRENAVALFSHPAKPGGAKWVADALQRNAGL
CCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCH
LAQIRRRLGAIRPDRTILRGQTAGDEIDLDAVVAARGERRAGATGDARFYRSRRPAPRTL
HHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCEE
ALVLLVDASASTDAWVTRKDRVIDIEKEAALLAAAGLETLRTRFAVLAFSGEGPAGVQIR
EEEEEEECCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHH
EIKRFDETWDASAQRRLAGLEPDRYTRLGAALRHANALLAACAADHRLLLLLSDGRPNDC
HHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHH
DRYASRYGIEDARQALTEARLKRISPYCFTVDRAGGSYLPTIFGSEGYTVVQHPQQLPVA
HHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCCEEECCCCCCHHH
FINWLRRAARVCMR
HHHHHHHHHHHHCC
>Mature Secondary Structure 
PEAEELIIDAARHAGTAVHGFWRRRHAPPPTPTVFLRDVRTRLEMLIDAVLGCELPVRA
CCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AQAAAPMPLLRRLFTRGGRKTAAAGPLPATDGTAVFLPPSLPVSPPASAAFTDDYCLLAL
HHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHH
LQALHHLRGSAGEIARLESDLARDLYLIAEAAAVDHRLRRLMPGWSQALDALYVRMDRAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AQRRLRDALEADVAARYRNFLRGRAGAETLHANPAAALDWANAQARALRLRVPARRYVAW
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHCCCCCHHHEEEEECCHHHHHHH
LGDLVVGRLLPPEGAPRARVRASSKAAAAADARAGARTASLVRRPRVRDGRDEDDAKPGV
HHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCC
SMVQTSEPHPHAEDPFGLNRPEDQEPEDDLGGAAESLAEMEEARLVHSPGAAREAFEASD
CEEECCCCCCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
PPPRLESAADTALPPCAFSYPEWDCRTSRYRENAVALFSHPAKPGGAKWVADALQRNAGL
CCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCH
LAQIRRRLGAIRPDRTILRGQTAGDEIDLDAVVAARGERRAGATGDARFYRSRRPAPRTL
HHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCEE
ALVLLVDASASTDAWVTRKDRVIDIEKEAALLAAAGLETLRTRFAVLAFSGEGPAGVQIR
EEEEEEECCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHH
EIKRFDETWDASAQRRLAGLEPDRYTRLGAALRHANALLAACAADHRLLLLLSDGRPNDC
HHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHH
DRYASRYGIEDARQALTEARLKRISPYCFTVDRAGGSYLPTIFGSEGYTVVQHPQQLPVA
HHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCCEEECCCCCCHHH
FINWLRRAARVCMR
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA