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The map label for this gene is nagZ

Identifier: 74316745

GI number: 74316745

Start: 769602

End: 770681

Strand: Reverse

Name: nagZ

Synonym: Tbd_0727

Alternate gene names: 74316745

Gene position: 770681-769602 (Counterclockwise)

Preceding gene: 74316746

Following gene: 74316744

Centisome position: 26.49

GC content: 72.13

Gene sequence:

>1080_bases
GTGACCCTTGGACCCTTGATGCTCGACGTCGCCGGCACCGAACTGTGCGACGACGACCGCCGCCGCCTCAGCGACCCGCT
GGTCGGCGGCGTCATTCTTTTCTCGCGCAACTACCGCGACCCGGCGCAGCTCGCCGCGCTGTGCGAGGAGATCCACGCGC
TCAAGGCCGCGCCGCTCCTGATCGGCGTCGACCACGAAGGCGGGCGCGTGCAGCGCTTCCGCGACGGCTTCACCCGCCTG
CCGCCGATGCGCAGCCTCGGCGCGATCTGGAACGAGCACCCGCAGCGCGCCCGCGAACTCGCGCGCGAGACCGGCTACGT
GCTCGCAAGCGAGCTGCGCGCGCACGGCGTCGACTTCAGCTTCGCGCCCGTGCTCGACCTCGACTACGGCGCGTCGTCGG
TGATCGGCGACCGCGCCTTCCACGCCGACCCGCAGGCCGTGTTCCAGCTCGGGCAGGCGGTCATGCTCGGCATGAAGGAC
GCCGGCATGGCGGCCTGCGGCAAGCACTTCCCCGGCCACGGCTTCGTCATCGCCGATTCGCACGTCGACATTCCGGTCGA
CCGACGCACGCTCGGCGACATCGCTCGCGCCGACCTGGTGCCCTTCCGCCTGATGGTCGAGGCCGGGCTCGCGGCGATGA
TGCCCGCGCACGTGATCTATCCCGAGGTCGACGCGCAGCCGGCCGGCTTCTCGCGCGTCTGGCTGCAGAAGATCCTGCGC
CAGCAACTCGGCTTCGACGGCGCGGTGTTCAGCGACGACCTGTGCATGGCCGGCGCGGCGTTCGCCGGCGGCATCGTCGA
GCGCGTGCGGGCCGCGCTCGACGCCGGCTGCGACATGGCCCTCGTGTGCAACCACCCCGAGCTTGCCGACGAGGTGCTGG
CCAAGCTCGACGTCGACTGGCCGGCCCCGGCGCGCGCGCGGCTCGCGCGCATGCACGGCCATCCCGCCCACGCGCCGACG
ATGACCGCGCTGCGCGAATCGGCGCGTTATGCCGAGGCGCTGCACCACGTCGCCGGGCTCGGCCGGGATTCCGCCGAACT
CGATCTGTCCGACCCGACCGACTACTGTGGCCGCGCATAA

Upstream 100 bases:

>100_bases
GAACGCGGCGTCACCGCGCAGCACGTTTCGCTTTCCGACGAGGGCGACTTCGTGCTCGCCTTCGTCGTGCTCGAACAATC
CGCGACGCAGGAGGACTGAC

Downstream 100 bases:

>100_bases
GCACGACCACGCCGGCCACACGCACTTTCACGGCGCGCACGCGGGCGGGAGCCGCACGCTGCTCGTCGCGCTACTGCTGA
CGCTCGCGTTCGCCGGCATC

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MTLGPLMLDVAGTELCDDDRRRLSDPLVGGVILFSRNYRDPAQLAALCEEIHALKAAPLLIGVDHEGGRVQRFRDGFTRL
PPMRSLGAIWNEHPQRARELARETGYVLASELRAHGVDFSFAPVLDLDYGASSVIGDRAFHADPQAVFQLGQAVMLGMKD
AGMAACGKHFPGHGFVIADSHVDIPVDRRTLGDIARADLVPFRLMVEAGLAAMMPAHVIYPEVDAQPAGFSRVWLQKILR
QQLGFDGAVFSDDLCMAGAAFAGGIVERVRAALDAGCDMALVCNHPELADEVLAKLDVDWPAPARARLARMHGHPAHAPT
MTALRESARYAEALHHVAGLGRDSAELDLSDPTDYCGRA

Sequences:

>Translated_359_residues
MTLGPLMLDVAGTELCDDDRRRLSDPLVGGVILFSRNYRDPAQLAALCEEIHALKAAPLLIGVDHEGGRVQRFRDGFTRL
PPMRSLGAIWNEHPQRARELARETGYVLASELRAHGVDFSFAPVLDLDYGASSVIGDRAFHADPQAVFQLGQAVMLGMKD
AGMAACGKHFPGHGFVIADSHVDIPVDRRTLGDIARADLVPFRLMVEAGLAAMMPAHVIYPEVDAQPAGFSRVWLQKILR
QQLGFDGAVFSDDLCMAGAAFAGGIVERVRAALDAGCDMALVCNHPELADEVLAKLDVDWPAPARARLARMHGHPAHAPT
MTALRESARYAEALHHVAGLGRDSAELDLSDPTDYCGRA
>Mature_358_residues
TLGPLMLDVAGTELCDDDRRRLSDPLVGGVILFSRNYRDPAQLAALCEEIHALKAAPLLIGVDHEGGRVQRFRDGFTRLP
PMRSLGAIWNEHPQRARELARETGYVLASELRAHGVDFSFAPVLDLDYGASSVIGDRAFHADPQAVFQLGQAVMLGMKDA
GMAACGKHFPGHGFVIADSHVDIPVDRRTLGDIARADLVPFRLMVEAGLAAMMPAHVIYPEVDAQPAGFSRVWLQKILRQ
QLGFDGAVFSDDLCMAGAAFAGGIVERVRAALDAGCDMALVCNHPELADEVLAKLDVDWPAPARARLARMHGHPAHAPTM
TALRESARYAEALHHVAGLGRDSAELDLSDPTDYCGRA

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily

Homologues:

Organism=Escherichia coli, GI1787350, Length=330, Percent_Identity=48.7878787878788, Blast_Score=290, Evalue=7e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGZ_THIDA (Q3SKU2)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314485.1
- ProteinModelPortal:   Q3SKU2
- SMR:   Q3SKU2
- STRING:   Q3SKU2
- GeneID:   3673818
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0727
- NMPDR:   fig|292415.3.peg.883
- eggNOG:   COG1472
- HOGENOM:   HBG617255
- OMA:   DLTMEGA
- PhylomeDB:   Q3SKU2
- ProtClustDB:   PRK05337
- BioCyc:   TDEN292415:TBD_0727-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00364
- InterPro:   IPR022956
- InterPro:   IPR001764
- InterPro:   IPR017853
- Gene3D:   G3DSA:3.20.20.300

Pfam domain/function: PF00933 Glyco_hydro_3; SSF51445 Glyco_hydro_cat

EC number: =3.2.1.52

Molecular weight: Translated: 38793; Mature: 38662

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: ACT_SITE 252-252

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLGPLMLDVAGTELCDDDRRRLSDPLVGGVILFSRNYRDPAQLAALCEEIHALKAAPLL
CCCCCEEHHHCCCHHCCHHHHHHHCCHHCEEEEEECCCCCHHHHHHHHHHHHHHHHCCEE
IGVDHEGGRVQRFRDGFTRLPPMRSLGAIWNEHPQRARELARETGYVLASELRAHGVDFS
EEECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
FAPVLDLDYGASSVIGDRAFHADPQAVFQLGQAVMLGMKDAGMAACGKHFPGHGFVIADS
CCCEEECCCCCHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECC
HVDIPVDRRTLGDIARADLVPFRLMVEAGLAAMMPAHVIYPEVDAQPAGFSRVWLQKILR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHH
QQLGFDGAVFSDDLCMAGAAFAGGIVERVRAALDAGCDMALVCNHPELADEVLAKLDVDW
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCC
PAPARARLARMHGHPAHAPTMTALRESARYAEALHHVAGLGRDSAELDLSDPTDYCGRA
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure 
TLGPLMLDVAGTELCDDDRRRLSDPLVGGVILFSRNYRDPAQLAALCEEIHALKAAPLL
CCCCEEHHHCCCHHCCHHHHHHHCCHHCEEEEEECCCCCHHHHHHHHHHHHHHHHCCEE
IGVDHEGGRVQRFRDGFTRLPPMRSLGAIWNEHPQRARELARETGYVLASELRAHGVDFS
EEECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
FAPVLDLDYGASSVIGDRAFHADPQAVFQLGQAVMLGMKDAGMAACGKHFPGHGFVIADS
CCCEEECCCCCHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECC
HVDIPVDRRTLGDIARADLVPFRLMVEAGLAAMMPAHVIYPEVDAQPAGFSRVWLQKILR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHHH
QQLGFDGAVFSDDLCMAGAAFAGGIVERVRAALDAGCDMALVCNHPELADEVLAKLDVDW
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCC
PAPARARLARMHGHPAHAPTMTALRESARYAEALHHVAGLGRDSAELDLSDPTDYCGRA
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA