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The map label for this gene is acpS

Identifier: 74316746

GI number: 74316746

Start: 770683

End: 771078

Strand: Reverse

Name: acpS

Synonym: Tbd_0728

Alternate gene names: 74316746

Gene position: 771078-770683 (Counterclockwise)

Preceding gene: 74316747

Following gene: 74316745

Centisome position: 26.5

GC content: 70.45

Gene sequence:

>396_bases
ATGATCCACGGCATCGGCACCGACCTGCTCGACGCGCGCCGCATCCGCGCCGGGCTCGCGCGCTACGGCGAGCACTACGC
CGACCGCATCCTCGCGCCGGCCGAGCACACGCGCTATTACGCGAGCCGCGACCCCGCGGGCTTTCTCGCCAAGTGCTTCG
CCGCCAAGGAAGCCTTCGCCAAGGCGCTCGGCACGGGGCTGCGCGCGCCGGTCACGCTGCGCAACATCGCCGTCATGCGC
GACGCGCACGGCAAGCCCCACATCGACTGCGCGCCCGAACTCACCGCGTTTCTGCGCGAACGCGGCGTCACCGCGCAGCA
CGTTTCGCTTTCCGACGAGGGCGACTTCGTGCTCGCCTTCGTCGTGCTCGAACAATCCGCGACGCAGGAGGACTGA

Upstream 100 bases:

>100_bases
TGCAGCCGCAGGCGAGCCGGCTCTCGGCGCTGCCGGCCGAATGGCTCGAGGCTTACGCCGAGCGGATTCGCGCCGCGGGC
CTGCCGGTGCGCGTCTCGCC

Downstream 100 bases:

>100_bases
CGTGACCCTTGGACCCTTGATGCTCGACGTCGCCGGCACCGAACTGTGCGACGACGACCGCCGCCGCCTCAGCGACCCGC
TGGTCGGCGGCGTCATTCTT

Product: Holo-acyl carrier protein synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MIHGIGTDLLDARRIRAGLARYGEHYADRILAPAEHTRYYASRDPAGFLAKCFAAKEAFAKALGTGLRAPVTLRNIAVMR
DAHGKPHIDCAPELTAFLRERGVTAQHVSLSDEGDFVLAFVVLEQSATQED

Sequences:

>Translated_131_residues
MIHGIGTDLLDARRIRAGLARYGEHYADRILAPAEHTRYYASRDPAGFLAKCFAAKEAFAKALGTGLRAPVTLRNIAVMR
DAHGKPHIDCAPELTAFLRERGVTAQHVSLSDEGDFVLAFVVLEQSATQED
>Mature_131_residues
MIHGIGTDLLDARRIRAGLARYGEHYADRILAPAEHTRYYASRDPAGFLAKCFAAKEAFAKALGTGLRAPVTLRNIAVMR
DAHGKPHIDCAPELTAFLRERGVTAQHVSLSDEGDFVLAFVVLEQSATQED

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=124, Percent_Identity=38.7096774193548, Blast_Score=86, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_THIDA (Q3SKU1)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314486.1
- ProteinModelPortal:   Q3SKU1
- SMR:   Q3SKU1
- STRING:   Q3SKU1
- GeneID:   3673819
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0728
- NMPDR:   fig|292415.3.peg.884
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q3SKU1
- BioCyc:   TDEN292415:TBD_0728-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14319; Mature: 14319

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHGIGTDLLDARRIRAGLARYGEHYADRILAPAEHTRYYASRDPAGFLAKCFAAKEAFA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
KALGTGLRAPVTLRNIAVMRDAHGKPHIDCAPELTAFLRERGVTAQHVSLSDEGDFVLAF
HHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEH
VVLEQSATQED
EEHHHHCCCCC
>Mature Secondary Structure
MIHGIGTDLLDARRIRAGLARYGEHYADRILAPAEHTRYYASRDPAGFLAKCFAAKEAFA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
KALGTGLRAPVTLRNIAVMRDAHGKPHIDCAPELTAFLRERGVTAQHVSLSDEGDFVLAF
HHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEH
VVLEQSATQED
EEHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA