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The map label for this gene is fixN [H]

Identifier: 74316661

GI number: 74316661

Start: 681042

End: 682463

Strand: Reverse

Name: fixN [H]

Synonym: Tbd_0643

Alternate gene names: 74316661

Gene position: 682463-681042 (Counterclockwise)

Preceding gene: 74316662

Following gene: 74316660

Centisome position: 23.45

GC content: 62.31

Gene sequence:

>1422_bases
ATGGAAGCGGCAACCTACAACTACAAAGTGGTCCGCCAGTTCGCCATCATGACGGTGGTGTGGGGGATCGTCGGCATGTT
GGTGGGGGTGATCATCGCCTCGCAACTGATCTGGCCCGACCTGACGTTCGGCATCGAATGGCTTTCCTACGGGCGTCTGC
GGCCGCTGCATACGAACGCGGTGATCTTCGCCTTCGGCGGCTCGGCGATGTTCGCCGTGTCCTACTACATCGTCCAGCGC
ACCTGCCAGGTGCGACTTTGGGCCGAGAAGCTCGCGGCCTTCACGTTCTGGGGCTGGATGGCGGTGATCGTGCTGGCGGC
GATCTCGCTGCCGATGGGCTACACGAGTTCGAAGGAATACGCCGAGCTCGAGTGGCCGATCGATCTCCTGATCGCCGCCG
TCTGGGTGTCCTACGCGCTGGTGTTCTTCGGCACCATCGTCAAGCGCAAGACGAAACATATCTACGTCTCGAACTGGTTC
TTCGGCGCCTACATTCTCGTGATCGCGCTGCTGCACATCGTCAACAGCGCCGAGCTGCCGGTGACCTTGACCAAGTCCTA
CTCGGCCTACGCCGGCGTACAGGACGCGATGGTGCAGTGGTGGTACGGGCACAACGCGGTCGGCTTCTTCTTGACCACCG
CCTTCCTCGGCATGATGTACTACTTCATTCCGAAGCAGGCCGGGCGGCCGATCTACTCGTATCGGCTTTCAGTGGTTCAC
TTCTGGTCGCTCAACTTCATCTACATGTGGGCCGGCCCGCACCATCTGCAATACACAGCGCTGCCCGACTGGGCGCAGTC
GCTCGGCATGGTGTTTTCGCTGATGCTGCTCGCGCCGTCGTGGGGCGGCATGATGAACGGGATCATGACGCTGTCGGGCG
CATGGCACAAACTGCGCACCGACCCGATCCTCAAGTTCATGGTCACTGCGCTGTCGTTCTACGGCATGTCGACCTTCGAA
GGGCCGATGATGTCGATCAAGACCGTCAACGCGCTCTCGCACTACACCGAATGGACCGTCGGCCACGTGCACTCGGGCGC
GCTCGGCTGGGTCGCGATGATCACGATCGGCTCGATGTACTACCTGATCCCGCGGCTCTTCGGCCGTGATTCGATGGCGA
GCATACGGCTGATCGAGTGGCACTTCTGGCTGTCGACGATCGGCGTCGTGCTCTACATCGCGTCGATGTGGATCGCCGGT
GTCGCGCAGGGCCTGATGTGGCGCGCGGCGAACGCCGACGGCACGCTGGCGTACAGCTTCGCCCAGGTCGTCAACACGAT
GTATCCCTTCTACGGCATCCGTCTGCTCGGCGGCGCGATGTTCCTCTCGGGCATGCTGATGATGGCGTACAACGTCTGGC
AGACCGTCCGCGTCGGCCGCGTCGTCAACGACGCCCCGATCCCGCAAGCCGTCCACGCCTAA

Upstream 100 bases:

>100_bases
CCGACTAACGAGATATATTTATCCACATATGCGTAAATCATTATTGGATTCGCATGTACTAAACCAGTAATACAGTTATC
AATCACGGGAGGCGTGTGGA

Downstream 100 bases:

>100_bases
GGAGACCGACCATGATTTCGCATGAAAGCATTGAAAAGAACCTCGGTCTGCTGATCGTGCTGACCATCCTGATCGTCAGC
GTCGGCGGCCTGGTGCAGAT

Product: cytochrome c oxidase cbb3-type subunit I

Products: NA

Alternate protein names: Cytochrome CBB3 subunit 1; Cytochrome c oxidase polypeptide I homolog; Heme B/copper cytochrome c oxidase subunit [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MEAATYNYKVVRQFAIMTVVWGIVGMLVGVIIASQLIWPDLTFGIEWLSYGRLRPLHTNAVIFAFGGSAMFAVSYYIVQR
TCQVRLWAEKLAAFTFWGWMAVIVLAAISLPMGYTSSKEYAELEWPIDLLIAAVWVSYALVFFGTIVKRKTKHIYVSNWF
FGAYILVIALLHIVNSAELPVTLTKSYSAYAGVQDAMVQWWYGHNAVGFFLTTAFLGMMYYFIPKQAGRPIYSYRLSVVH
FWSLNFIYMWAGPHHLQYTALPDWAQSLGMVFSLMLLAPSWGGMMNGIMTLSGAWHKLRTDPILKFMVTALSFYGMSTFE
GPMMSIKTVNALSHYTEWTVGHVHSGALGWVAMITIGSMYYLIPRLFGRDSMASIRLIEWHFWLSTIGVVLYIASMWIAG
VAQGLMWRAANADGTLAYSFAQVVNTMYPFYGIRLLGGAMFLSGMLMMAYNVWQTVRVGRVVNDAPIPQAVHA

Sequences:

>Translated_473_residues
MEAATYNYKVVRQFAIMTVVWGIVGMLVGVIIASQLIWPDLTFGIEWLSYGRLRPLHTNAVIFAFGGSAMFAVSYYIVQR
TCQVRLWAEKLAAFTFWGWMAVIVLAAISLPMGYTSSKEYAELEWPIDLLIAAVWVSYALVFFGTIVKRKTKHIYVSNWF
FGAYILVIALLHIVNSAELPVTLTKSYSAYAGVQDAMVQWWYGHNAVGFFLTTAFLGMMYYFIPKQAGRPIYSYRLSVVH
FWSLNFIYMWAGPHHLQYTALPDWAQSLGMVFSLMLLAPSWGGMMNGIMTLSGAWHKLRTDPILKFMVTALSFYGMSTFE
GPMMSIKTVNALSHYTEWTVGHVHSGALGWVAMITIGSMYYLIPRLFGRDSMASIRLIEWHFWLSTIGVVLYIASMWIAG
VAQGLMWRAANADGTLAYSFAQVVNTMYPFYGIRLLGGAMFLSGMLMMAYNVWQTVRVGRVVNDAPIPQAVHA
>Mature_473_residues
MEAATYNYKVVRQFAIMTVVWGIVGMLVGVIIASQLIWPDLTFGIEWLSYGRLRPLHTNAVIFAFGGSAMFAVSYYIVQR
TCQVRLWAEKLAAFTFWGWMAVIVLAAISLPMGYTSSKEYAELEWPIDLLIAAVWVSYALVFFGTIVKRKTKHIYVSNWF
FGAYILVIALLHIVNSAELPVTLTKSYSAYAGVQDAMVQWWYGHNAVGFFLTTAFLGMMYYFIPKQAGRPIYSYRLSVVH
FWSLNFIYMWAGPHHLQYTALPDWAQSLGMVFSLMLLAPSWGGMMNGIMTLSGAWHKLRTDPILKFMVTALSFYGMSTFE
GPMMSIKTVNALSHYTEWTVGHVHSGALGWVAMITIGSMYYLIPRLFGRDSMASIRLIEWHFWLSTIGVVLYIASMWIAG
VAQGLMWRAANADGTLAYSFAQVVNTMYPFYGIRLLGGAMFLSGMLMMAYNVWQTVRVGRVVNDAPIPQAVHA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG3278

COG function: function code O; Cbb3-type cytochrome oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004677
- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 53350; Mature: 53350

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB ; PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8386371; 12597275 [H]